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AmbitionBoySchemeingInTheDarkness
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Frontiers | Cyclooxygenase (COX)-2 Inhibitors Reduce Toxoplasma gondii Infection and Upregulate the Pro-inflammatory Immune Response in Calomys callosus Rodents and Human Monocyte Cell Line
Toxoplasma gondii is able to infect a wide range of vertebrates, including humans. Studies show that cyclooxygenase-2 (COX-2) is a modulator of immune respon...
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the study used the COX-2 inhibitors meloxicam and celecoxib not aspirin , but aspirin also inhibits COX-2
"Parasite burden and COX-2 expression in C. callosus after infection with T. gondii and treatment with COX-2 inhibitors. Females were infected orally with 50 cysts of T. gondii (ME49 strain), treated or untreated with meloxicam (0.5 mg/kg) or celecoxib (5 mg/kg) daily, euthanized after 40 days of infection and treatment, and the brains collected and analyzed by real-time PCR to quantify the parasite burden"
"The data are shown as T. gondii DNA (TgDNA) concentration in 100 ng/μL total DNA"