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Kraken
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Firstly, you must realize the trade-off relationship between the objective of sexual success and the objective of youthfulness (health) preservation.
The Disposable Soma theory of aging states that:
“Organisms must devote limited resources either to produce more offspring or to live longer. Evolutionarily, it is beneficial to sacrifice the latter for the sake of the former.”
A problem with the Disposable Soma theory of aging is that if the resources were based on energy (measured in calories) then how come caloric restriction extends lifespan? A simple answer could be that the resource is not calories. But I have no lead on what that resource may be.
Well, another theory of aging based on trade-offs between sexual success and longevity is the Antagonistic Pleiotropy theory of aging. Pleiotropy is when a gene has multiple effects. Antagonistic Pleiotropy is when a gene has multiple effects, at least one beneficial and at least one detrimental. Usually, detrimental genes will get weeded out of the gene pool, but if that gene is packaged with a benefit as well that outweighs the draw-back, then that gene will be selected for through evolution. So this can relate to aging if a theoretical gene(s) increased reproductive fitness but accelerated aging.
You are hopefully aware of epigenetic alterations, which are alterations of gene expression, not genetic code, during an individual’s lifespan. I theorize that being around attractive females could upregulate genes that increase reproductive fitness, but this would come at the cost of increased aging if they were antagonistic pleiotropic genes that harmed longevity.
Evidence
Being around attractive females can increase testosterone:
https://pubmed.ncbi.nlm.nih.gov/18675269/
Based on the premise of the Disposable Soma theory, I speculate this also tells the body to allocate more resources (whatever that may be) to prepare for sexual success, which means less available for retaining your health/youth.
Based on the premise of the Antagonistic Pleiotropy theory of aging, I theorize that the increased testosterone either directly or indirectly upregulates genes associated with reproductive fitness, or that the increased testosterone indicates that those genes are being upregulated.
Fruit Fly Experiment:
Researchers exposed 33 day old virgin male fruit flies to female fruit flies for 48 hours (they were allowed to mate) and then all living males were “flash frozen” and their gene expression assayed. “Testis-specific” genes were upregulated and oxidation-reduction processes genes were down-regulated. Oxidation causes aging according to the Free Radical theory of aging so this is bad. Quite a lot of genes were affected and this also suggests that exposure to females in humans would affect gene expression.
Well, how did this affect their lifespan?
The black line is the survivor curve of virgin males and red is the survivorship of mated males (exposed to females from day 21-23)
Practicality:
Well, this suggests that we should avoid attractive females. Us basement dwellers probably already do IRL, but perhaps not online, which could potentially induce a similar response in our bodies. The main question is: to coom or not to coom? Based on the fruit fly study, I would propose NoFap as the answer. But remember the study on exposure of human males to attractive females? That study claims that no sexual activity in the past month increased the testosterone production response to attractive females. NoFap may therefore sensitize one to female exposure, even perhaps it may raise sex drive and therefore more resources will be allocated to the objective of reproduction or more associated genes upregulated. So I would say that reducing sex drive chemically or some other way would be the best option for longevity.
If you’re interested in more interesting anti-aging material:
@howtallareyou @crisis @Ragnar @Eriot Lodger @Nad @Suimaxxer @Kroker @Interested @CoffeeCel @HOLYFUARK @Acne Victim @Osie
The Disposable Soma theory of aging states that:
“Organisms must devote limited resources either to produce more offspring or to live longer. Evolutionarily, it is beneficial to sacrifice the latter for the sake of the former.”
A problem with the Disposable Soma theory of aging is that if the resources were based on energy (measured in calories) then how come caloric restriction extends lifespan? A simple answer could be that the resource is not calories. But I have no lead on what that resource may be.
Well, another theory of aging based on trade-offs between sexual success and longevity is the Antagonistic Pleiotropy theory of aging. Pleiotropy is when a gene has multiple effects. Antagonistic Pleiotropy is when a gene has multiple effects, at least one beneficial and at least one detrimental. Usually, detrimental genes will get weeded out of the gene pool, but if that gene is packaged with a benefit as well that outweighs the draw-back, then that gene will be selected for through evolution. So this can relate to aging if a theoretical gene(s) increased reproductive fitness but accelerated aging.
You are hopefully aware of epigenetic alterations, which are alterations of gene expression, not genetic code, during an individual’s lifespan. I theorize that being around attractive females could upregulate genes that increase reproductive fitness, but this would come at the cost of increased aging if they were antagonistic pleiotropic genes that harmed longevity.
Evidence
Being around attractive females can increase testosterone:
https://pubmed.ncbi.nlm.nih.gov/18675269/
Based on the premise of the Disposable Soma theory, I speculate this also tells the body to allocate more resources (whatever that may be) to prepare for sexual success, which means less available for retaining your health/youth.
Based on the premise of the Antagonistic Pleiotropy theory of aging, I theorize that the increased testosterone either directly or indirectly upregulates genes associated with reproductive fitness, or that the increased testosterone indicates that those genes are being upregulated.
Fruit Fly Experiment:
Researchers exposed 33 day old virgin male fruit flies to female fruit flies for 48 hours (they were allowed to mate) and then all living males were “flash frozen” and their gene expression assayed. “Testis-specific” genes were upregulated and oxidation-reduction processes genes were down-regulated. Oxidation causes aging according to the Free Radical theory of aging so this is bad. Quite a lot of genes were affected and this also suggests that exposure to females in humans would affect gene expression.
Well, how did this affect their lifespan?
The black line is the survivor curve of virgin males and red is the survivorship of mated males (exposed to females from day 21-23)
Practicality:
Well, this suggests that we should avoid attractive females. Us basement dwellers probably already do IRL, but perhaps not online, which could potentially induce a similar response in our bodies. The main question is: to coom or not to coom? Based on the fruit fly study, I would propose NoFap as the answer. But remember the study on exposure of human males to attractive females? That study claims that no sexual activity in the past month increased the testosterone production response to attractive females. NoFap may therefore sensitize one to female exposure, even perhaps it may raise sex drive and therefore more resources will be allocated to the objective of reproduction or more associated genes upregulated. So I would say that reducing sex drive chemically or some other way would be the best option for longevity.
If you’re interested in more interesting anti-aging material:
My interesting excerpts of ANTI-AGING literature!
This study proved that controlling time-of-feeding can override the anti-longevity effect of caloric intake and is sufficient for lifespan extension [88]. Caloric restriction, limiting calorie intake without causing malnutrition, has been shown to extend lifespan in multiple model systems (de...
looksmax.org
@howtallareyou @crisis @Ragnar @Eriot Lodger @Nad @Suimaxxer @Kroker @Interested @CoffeeCel @HOLYFUARK @Acne Victim @Osie