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There is more noise around training splits than almost any other topic. This thread cuts through that and gives a direct breakdown of which splits are worth running for maximum hypertrophy, ranked by how well they hold up against practical application.
My ranking criteria: Weekly volume per muscle group, frequency optimization, recovery management, structure, and real-world adherence.
THE SPLITS RANKED
[S TIER] Full Body Every Other Day (FBEOD)
FBEOD is the most mechanically sound split for hypertrophy at an intermediate level. Every muscle group is trained every 48–72 hours, which aligns directly with the protein synthesis window observed in muscle tissue. You accumulate high weekly frequency without any single session becoming unsustainable in volume.
Training each muscle 3+ times per week consistently outperforms lower frequency approaches in hypertrophy research. FBEOD delivers this automatically. The structure forces compound movement prioritization, keeps sessions manageable, and produces the most even muscular development of any common split. For someone optimizing purely for muscle growth, this is the default recommendation.
[S TIER] Anterior / Posterior (AP Split)
The AP split divides the body into front-chain and back-chain sessions rather than the outdated push/pull/legs or body-part categorization. This approach is anatomically intelligent — it groups muscles by movement pattern and mechanical synergy.
The AP split produces exceptional structural balance and eliminates the common lagging posterior chain seen in bro splits. Because antagonist groups are trained on separate days, each session allows higher intensities on compound movements. On a 4-day AP schedule, you achieve near-optimal weekly frequency with clean recovery. It is also superior to PPL for upper-body development because it separates fatigue patterns more naturally than a push/pull division.
FULL COMPARISON TABLE
NOTES ON COMMON SPLITS
Upper / Lower- Solid and well-supported. A 4-day upper/lower is a reliable A-tier option. It falls short of the top two primarily because it does not inherently optimize anterior/posterior chain balance the way AP does, and frequency is lower than FBEOD. Still a strong default for anyone training 4 days.
Push / Pull / Legs- PPL on 6 days gets reasonable frequency but is mechanically inferior to AP because the push/pull division creates compound fatigue overlap — shoulder fatigue from push days bleeds into pulling sessions in ways that AP separation avoids. The 3-day PPL cycle only hits each muscle once per week, which is functionally a bro split with extra steps.
Bro Split- One session per muscle per week is the single largest structural disadvantage a split can have. Protein synthesis in trained individuals peaks at 24–48 hours and largely returns to baseline by 72 hours. Waiting 7 days to restimulate a muscle leaves significant hypertrophic stimulus on the table every single week. It is not an effective choice for maximizing muscle growth regardless of in-session volume.
WHICH TO RUN
SUMMARY
The research on training frequency is not ambiguous. Higher frequency within a recoverable volume range consistently produces superior hypertrophy outcomes. FBEOD and the AP split are the two structures best designed around this principle. Everything else involves meaningful tradeoffs that reduce their ceiling.
Scientific Literature used to back my claims:
(If you are interested in these, I can send more and more recent studies if ur interested lmk)
Schoenfeld, Brad J., Dan Ogborn, and James W. Krieger. "Effects of Resistance Training Frequency on Measures of Muscle Hypertrophy: A Systematic Review and Meta-Analysis." Journal of Sports Sciences, vol. 34, no. 13, 2016, pp. 1247–1253. PubMed, https://pubmed.ncbi.nlm.nih.gov/27102172/.
Schoenfeld, Brad J., et al. "How Many Times per Week Should a Muscle Be Trained to Maximize Muscle Hypertrophy? A Systematic Review and Meta-Analysis of Studies Examining the Effects of Resistance Training Frequency." Journal of Strength and Conditioning Research, vol. 33, no. 7, 2019, pp. 1906–1914. PubMed, https://pubmed.ncbi.nlm.nih.gov/30558493/.
Neves, Rodrigo P., et al. "Effect of Different Training Frequencies on Maximal Strength Performance and Muscle Hypertrophy in Trained Individuals — A Within-Subject Design." PLOS ONE, vol. 17, no. 10, 2022. PLOS ONE, https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0276154.
Hamarsland, Håvard, et al. "Equal-Volume Strength Training With Different Training Frequencies Induces Similar Muscle Hypertrophy and Strength Improvement in Trained Participants." Frontiers in Physiology, vol. 12, 2022, article 789403. Frontiers, https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2021.789403/full.
Nishimura, Akihiro, et al. "Higher Training Frequency Is Important for Gaining Muscular Strength Under Volume-Matched Training." Frontiers in Physiology, vol. 9, 2018, article 744. Frontiers, https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2018.00744/full.
Ralston, Grant W., et al. "The Effectiveness of Frequency-Based Resistance Training Protocols on Muscular Performance and Hypertrophy in Trained Males." Journal of Sport Rehabilitation, vol. 29, no. 7, 2020, pp. 1024–1032. Human Kinetics, https://journals.humankinetics.com/view/journals/jsr/29/7/article-p1024.xml.
Nuckols, Greg. "Training Frequency for Muscle Growth: What the Data Say." Stronger by Science, 26 Jan. 2020, https://www.strongerbyscience.com/frequency-muscle/.
Nuckols, Greg. "When and How to Increase Training Frequency." MASS Research Review, 15 Jan. 2024, https://massresearchreview.com/2024/01/15/when-and-how-to-increase-training-frequency/.
hope yall found this helpful, if you see any mistake or got any question, send me them.
(Note, I am new to posting and dont get this formatting shit so dont be surprised if I formatted this like a fucktard)
My ranking criteria: Weekly volume per muscle group, frequency optimization, recovery management, structure, and real-world adherence.
THE SPLITS RANKED
[S TIER] Full Body Every Other Day (FBEOD)
FBEOD is the most mechanically sound split for hypertrophy at an intermediate level. Every muscle group is trained every 48–72 hours, which aligns directly with the protein synthesis window observed in muscle tissue. You accumulate high weekly frequency without any single session becoming unsustainable in volume.
- Frequency: 3–4x per muscle group per week
- Recovery: Built-in rest days between full sessions
- Weekly volume: Easily 15–25+ sets per muscle across the week
- Flexibility: Works Mon/Wed/Fri or any alternating schedule
Training each muscle 3+ times per week consistently outperforms lower frequency approaches in hypertrophy research. FBEOD delivers this automatically. The structure forces compound movement prioritization, keeps sessions manageable, and produces the most even muscular development of any common split. For someone optimizing purely for muscle growth, this is the default recommendation.
[S TIER] Anterior / Posterior (AP Split)
The AP split divides the body into front-chain and back-chain sessions rather than the outdated push/pull/legs or body-part categorization. This approach is anatomically intelligent — it groups muscles by movement pattern and mechanical synergy.
- Anterior day: Quads, chest, front delts, biceps, abs
- Posterior day: Hamstrings, glutes, back, rear delts, triceps, calves
- Frequency: 2x per muscle at minimum; 4x on a 4-day schedule
- Overlap: Minimal — anterior and posterior groups do not significantly fatigue each other
The AP split produces exceptional structural balance and eliminates the common lagging posterior chain seen in bro splits. Because antagonist groups are trained on separate days, each session allows higher intensities on compound movements. On a 4-day AP schedule, you achieve near-optimal weekly frequency with clean recovery. It is also superior to PPL for upper-body development because it separates fatigue patterns more naturally than a push/pull division.
FULL COMPARISON TABLE
| Split | Freq/Muscle | Volume Ceiling | Recovery | Balance | Overall |
|---|---|---|---|---|---|
| FBEOD | 3–4x | BEST | Excellent | Excellent | S Tier |
| Anterior/Posterior | 2–4x | Very High | BEST | Excellent | S Tier |
| Upper/Lower (4-day) | 2x | High | Good | Good | A Tier |
| PPL (6-day) | 2x | High | Moderate | Moderate | A Tier |
| PPL (3-day) | 1x | Moderate | Good | Moderate | B Tier |
| Upper/Lower (2-day) | 1x | Low | Excellent | Good | B Tier |
| Bro Split (5-day) | 1x | Moderate | Good | Poor | C Tier |
NOTES ON COMMON SPLITS
Upper / Lower- Solid and well-supported. A 4-day upper/lower is a reliable A-tier option. It falls short of the top two primarily because it does not inherently optimize anterior/posterior chain balance the way AP does, and frequency is lower than FBEOD. Still a strong default for anyone training 4 days.
Push / Pull / Legs- PPL on 6 days gets reasonable frequency but is mechanically inferior to AP because the push/pull division creates compound fatigue overlap — shoulder fatigue from push days bleeds into pulling sessions in ways that AP separation avoids. The 3-day PPL cycle only hits each muscle once per week, which is functionally a bro split with extra steps.
Bro Split- One session per muscle per week is the single largest structural disadvantage a split can have. Protein synthesis in trained individuals peaks at 24–48 hours and largely returns to baseline by 72 hours. Waiting 7 days to restimulate a muscle leaves significant hypertrophic stimulus on the table every single week. It is not an effective choice for maximizing muscle growth regardless of in-session volume.
WHICH TO RUN
3–4 days available → Run FBEOD. Most frequency-efficient split in existence. Three full body sessions per week outperforms nearly every other structure for intermediate-level muscle growth.
4–5 days available, prefer structure → Run Anterior/Posterior. Four days of AP gives you elite frequency, excellent balance, and clean recovery. The most anatomically intelligent split for a proportionate physique.
6+ days available → FBEOD or AP on an extended cycle, not a 6-day bro split. More days do not produce more growth if frequency per muscle is not increasing.
SUMMARY
The research on training frequency is not ambiguous. Higher frequency within a recoverable volume range consistently produces superior hypertrophy outcomes. FBEOD and the AP split are the two structures best designed around this principle. Everything else involves meaningful tradeoffs that reduce their ceiling.
Scientific Literature used to back my claims:
(If you are interested in these, I can send more and more recent studies if ur interested lmk)
Schoenfeld, Brad J., Dan Ogborn, and James W. Krieger. "Effects of Resistance Training Frequency on Measures of Muscle Hypertrophy: A Systematic Review and Meta-Analysis." Journal of Sports Sciences, vol. 34, no. 13, 2016, pp. 1247–1253. PubMed, https://pubmed.ncbi.nlm.nih.gov/27102172/.
Schoenfeld, Brad J., et al. "How Many Times per Week Should a Muscle Be Trained to Maximize Muscle Hypertrophy? A Systematic Review and Meta-Analysis of Studies Examining the Effects of Resistance Training Frequency." Journal of Strength and Conditioning Research, vol. 33, no. 7, 2019, pp. 1906–1914. PubMed, https://pubmed.ncbi.nlm.nih.gov/30558493/.
Neves, Rodrigo P., et al. "Effect of Different Training Frequencies on Maximal Strength Performance and Muscle Hypertrophy in Trained Individuals — A Within-Subject Design." PLOS ONE, vol. 17, no. 10, 2022. PLOS ONE, https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0276154.
Hamarsland, Håvard, et al. "Equal-Volume Strength Training With Different Training Frequencies Induces Similar Muscle Hypertrophy and Strength Improvement in Trained Participants." Frontiers in Physiology, vol. 12, 2022, article 789403. Frontiers, https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2021.789403/full.
Nishimura, Akihiro, et al. "Higher Training Frequency Is Important for Gaining Muscular Strength Under Volume-Matched Training." Frontiers in Physiology, vol. 9, 2018, article 744. Frontiers, https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2018.00744/full.
Ralston, Grant W., et al. "The Effectiveness of Frequency-Based Resistance Training Protocols on Muscular Performance and Hypertrophy in Trained Males." Journal of Sport Rehabilitation, vol. 29, no. 7, 2020, pp. 1024–1032. Human Kinetics, https://journals.humankinetics.com/view/journals/jsr/29/7/article-p1024.xml.
Nuckols, Greg. "Training Frequency for Muscle Growth: What the Data Say." Stronger by Science, 26 Jan. 2020, https://www.strongerbyscience.com/frequency-muscle/.
Nuckols, Greg. "When and How to Increase Training Frequency." MASS Research Review, 15 Jan. 2024, https://massresearchreview.com/2024/01/15/when-and-how-to-increase-training-frequency/.
hope yall found this helpful, if you see any mistake or got any question, send me them.
(Note, I am new to posting and dont get this formatting shit so dont be surprised if I formatted this like a fucktard)