TheGreatMountTai
Fatmaxxing
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Penile atrophy (shrinkage), reduction in length or girth, and decreased genital sensitivity are reported as part of Post-Finasteride Syndrome (PFS), a set of persistent sexual, physical, and mental side effects in some men taking finasteride.
While not officially listed on the FDA-approved labeling, these symptoms are documented in clinical reviews and patient reports.
www.peoplespharmacy.com
PFS describes the persistent negative sexual, neurological, and physical symptoms in patients who have taken 5ARIs (3). Although sexual side effects of 5ARIs are well described in the literature, many questions still exist surrounding other side effects including severe depression (4), cognitive decline and genitourinary and musculoskeletal complaints. A recent review indicated that finasteride may impact the physical, psychiatric, and cognitive domains (5) in addition to sexual and genital function.
Most of the current literature on PFS supports increased rates of ED and low libido in patients taking 5ARIs (6). More worrisome, however, are data observing an increased risk of persistent sexual side effects despite discontinuation of the medication (7,8). In addition to ED and low libido, adverse effects of finasteride may include penile atrophy, diminished ejaculatory volume and force, and an increased incidence of Peyronie’s disease; the latter of which may be mediated by a decreased effect of DHT on male genitalia (9-11).
While not officially listed on the FDA-approved labeling, these symptoms are documented in clinical reviews and patient reports.
Prostate Drugs Finasteride and Dutasteride May Shrink Prostate AND Penis
Finasteride and dutasteride shrink prostate glands but can have sexual side effects: lower libido and less pleasure. What about penis size?
PFS describes the persistent negative sexual, neurological, and physical symptoms in patients who have taken 5ARIs (3). Although sexual side effects of 5ARIs are well described in the literature, many questions still exist surrounding other side effects including severe depression (4), cognitive decline and genitourinary and musculoskeletal complaints. A recent review indicated that finasteride may impact the physical, psychiatric, and cognitive domains (5) in addition to sexual and genital function.
Most of the current literature on PFS supports increased rates of ED and low libido in patients taking 5ARIs (6). More worrisome, however, are data observing an increased risk of persistent sexual side effects despite discontinuation of the medication (7,8). In addition to ED and low libido, adverse effects of finasteride may include penile atrophy, diminished ejaculatory volume and force, and an increased incidence of Peyronie’s disease; the latter of which may be mediated by a decreased effect of DHT on male genitalia (9-11).
