Can someone explain and teach me about these hairloss prevention stuff and if they’re a halo or failo (good or bad idea to use)

[RichardRich]

-cetirizine topical


-setipiprant topical


-tdm-105795 topical


-verteporfin (infinite hair transplant method)


-GT20029 topical


-alfatradiol topical



-Topical estriol and progesterone



Off topic question:
Also can I use topical finasteride/minoxidil mix while on oral dutasteride?

 

[7zyzz7]

the best hairloss treatments are scalp massage, a nice shampoo, and hair transplant everything else is a cope bandaid except for fin if u want to risk castration and min if u want heart palps

 

[AutistKhan]

A

-cetirizine topical


-setipiprant topical


-tdm-105795 topical


-verteporfin (infinite hair transplant method)


-GT20029 topical


-alfatradiol topical



-Topical estriol and progesterone



Off topic question:
Also can I use topical finasteride/minoxidil mix while on oral dutasteride?

Dude theyr all just un accessable drug or just estrogen mimic compounds your fucking up your health just use topical minox and dont be vitamin deficint until you get hairtransplant

 

[RichardRich]

the best hairloss treatments are scalp massage, a nice shampoo, and hair transplant everything else is a cope bandaid except for fin if u want to risk castration and min if u want heart palps

I’m already on the water information tier hairloss prevention and hair growth stuff, I wanna block everything that causes hairloss not just the water stuff like topical anti androgens and DHT blockers which I’m already on, I wanna nuke tf out of any pathway/hormones that causes Norwood reaper

 

[thegoldenlight]

the best hairloss treatments are scalp massage, a nice shampoo, and hair transplant everything else is a cope bandaid except for fin if u want to risk castration and min if u want heart palps

cope

 

[7zyzz7]

A

Dude theyr all just un accessable drug or just estrogen mimic compounds your fucking up your health just use topical minox and dont be vitamin deficint until you get hairtransplant

ngas would rather rub estrogen on their head and than do a scalp massage which has countless studies and anecdotes showing it being as effective as fin/min. And no the mechanism is not that more blood flow causes less hair loss but that the increased stimulation is actually cause a increase in progesterone in the hair cell which causes the DHT and cortisol of the hair to go lower.

 

[7zyzz7]

cope

Repeated scalp stretching → mechanical deformation of follicle-associated tissue → mechanosensitive signaling in dermal papilla cells → altered gene expression → longer/more robust anagen + less miniaturization.


Mechanical stimulus → integrins/cytoskeleton/mechanosensitive proteins → intracellular signaling → transcriptional changes in dermal papilla cells → altered follicle cycling and/or shaft caliber

 

[7zyzz7]

there could be like 20 different way that a scalp massage alter the hairs and causes less hairloss its not cope just try it.

 

[Prøphet]

alfatrafiol is shit not worth it

gt20029 is the most optimistic but I don't trust studies from Kintor that much

verteporfin sounds good mechanistically but still no nonfraudulent human evidence, although it does work in pigs

you can stack fin with dut some people react better to one of them just make you sure you don't get sides

 

[RichardRich]

View attachment 5681949View attachment 5681950View attachment 5681951View attachment 5681952

Repeated scalp stretching → mechanical deformation of follicle-associated tissue → mechanosensitive signaling in dermal papilla cells → altered gene expression → longer/more robust anagen + less miniaturization.


Mechanical stimulus → integrins/cytoskeleton/mechanosensitive proteins → intracellular signaling → transcriptional changes in dermal papilla cells → altered follicle cycling and/or shaft caliber

 

[thegoldenlight]

View attachment 5681949View attachment 5681950View attachment 5681951View attachment 5681952

Repeated scalp stretching → mechanical deformation of follicle-associated tissue → mechanosensitive signaling in dermal papilla cells → altered gene expression → longer/more robust anagen + less miniaturization.


Mechanical stimulus → integrins/cytoskeleton/mechanosensitive proteins → intracellular signaling → transcriptional changes in dermal papilla cells → altered follicle cycling and/or shaft caliber

bunch of bs, still cope

 

[RichardRich]

bunch of bs, still cope

Ik