Cilostazol is a elite bone growth drug

Cilostanzol is a vasodilator that works by relaxing the muscles in ur blood vessels to help them dilate-wided

The compound works for bone growth by elevating (cGMP) levels which promotes calcuim entry through TRPM7 channels enhacing bone growth

Cilostanzol also works as a pthrp analog and can double down by lowering fgr3 levels in bones and surporting (cAMP) receptors

Bone smashing in logic would be very viable with cilostazol

The drug is quite cheep and affordable and is a oral drug would recommend

The side affects could include head aches light headed and other symptons that would ocur with low blood pressure just remmeber to stay safe

 

[hypergamousfoids]

Cilostanzol is a vasodilator that works by relaxing the muscles in ur blood vessels to help them dilate-wided

The compound works for bone growth by elevating (cGMP) levels which promotes calcuim entry through TRPM7 channels enhacing bone growth

Cilostanzol also works as a pthrp analog and can double down by lowering fgr3 levels in bones and surporting (cAMP) receptors

Bone smashing in logic would be very viable with cilostazol

The drug is quite cheep and affordable and is a oral drug would recommend

The side affects could include head aches light headed and other symptons that would ocur with low blood pressure just remmeber to stay safe

you got any sources

 

[daudthe1_]

Cilostanzol is a vasodilator that works by relaxing the muscles in ur blood vessels to help them dilate-wided

The compound works for bone growth by elevating (cGMP) levels which promotes calcuim entry through TRPM7 channels enhacing bone growth

Cilostanzol also works as a pthrp analog and can double down by lowering fgr3 levels in bones and surporting (cAMP) receptors

Bone smashing in logic would be very viable with cilostazol

The drug is quite cheep and affordable and is a oral drug would recommend

The side affects could include head aches light headed and other symptons that would ocur with low blood pressure just remmeber to stay safe

Source? Also pth analogs can cause bone resorption if you're not careful

 

[holyhair6767]

any studies on this?

 

[Itsov3rlol]

Studies?

 

[nuclearNadal]

Non-unions represent a major complication in trauma and orthopedic surgery. Many factors contribute to bone regeneration, out of which an adequate vascularization has been recognized as crucial. The phosphodiesterase-3 (PDE-3) inhibitor cilostazol has been shown to exert pro-angiogenic and pro-osteogenic effects in a variety of preclinical studies. Hence, we herein investigated the effects of cilostazol on bone regeneration in an atrophic non-union model in mice. For this purpose, a 1.8 mm femoral segmental defect was stabilized by pin-clip fixation and the animals were treated daily with 30 mg/kg body weight cilostazol or saline (control) per os. At 2, 5 and 10 weeks after surgery the healing of femora was analyzed by X-ray, biomechanics, photoacoustic imaging, and micro-computed tomography (µCT). To investigate the cellular composition and the growth factor expression of the callus tissue additional histological, immunohistochemical and Western blot analyses were performed. Cilostazol-treated animals showed increased bone formation within the callus, resulting in an enhanced bending stiffness when compared to controls. This was associated with a more pronounced expression of vascular endothelial growth factor (VEGF), a higher number of CD31-positive microvessels and an increased oxygen saturation within the callus tissue. Furthermore, cilostazol induced higher numbers of tartrate-resistant acidic phosphate (TRAP)-positive osteoclasts and CD68-positive macrophages. Taken together, these findings demonstrate that cilostazol is a promising drug candidate for the adjuvant treatment of atrophic non-unions in clinical practice.



National Institutes of Health (.gov)

PubMed

PubMed® comprises more than 40 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.

pubmed.ncbi.nlm.nih.gov

Cilostazol promotes blood vessel formation and bone regeneration in a ...

 

[nuclearNadal]

any studies on this?

National Institutes of Health (.gov)

PubMed

PubMed® comprises more than 40 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.

pubmed.ncbi.nlm.nih.gov

Cilostazol promotes blood vessel formation and bone regeneration in a ...

 

[nuclearNadal]

you got any sources

Indiamart

 

[hypergamousfoids]

Indiamart

alright and last thing, sorry to ask im just too lazy to open a thread and ask but what is the triangle shipping method to not get seized, if you know ofc.

 

[nuclearNadal]

alright and last thing, sorry to ask im just too lazy to open a thread and ask but what is the triangle shipping method to not get seized, if you know ofc.

I dont know tbh

 

[holyhair6767]

alright and last thing, sorry to ask im just too lazy to open a thread and ask but what is the triangle shipping method to not get seized, if you know ofc.

its when you ship it to a company which relabels the package and then sends it to you im pretty sure