Clearing Up Misinformation about HGH.

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nakus

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I see alot of misinformation about HGH floating around this forum.

Insane idiots telling people to take 15IU's per day :ROFLMAO:
Idiots saying "HGH only works if it's pharma grade!" :ROFLMAO:
And so much other shit.

First of all, the approved dose for HGH by the FDA for Idiopathic Short Statue, will be referred as ISS, is 0.37 mg/kg/wk now explain to why the standard on this forum became "10IU's or Cope" fucking retards thinking they need more HGH then someone trying to catch up to their genetic height WITH A DEFICIENCY, meaning they are making up for the deficiency and adding on top of it.

Just to put it into perspective 10IU's would mean you weigh 200kg according to the FDA approved dosage for ISS. YOU DO NOT NEED THIS MUCH

I would say use the FDA dosage and if you really feel like "oh it's not enough man!!!:geek:" then add on 2IU's to the dosage and you'll be fine.

In my opinion, 5IU's would fit most people but use the dosage and make your dosage fit you.

In Pfizers Genotropin manual 3IU's per day is described as overdose and I hate to break it to you, but the difference on your height on 5IU's and 10IU's IS NOTHING :eek:

THE DIFFERENCE IN NOSE GAINS BETWEEN THE 2 IS A SIGNIFICANT INCREASE FOR 10IU'S :hnghn:


So stop spreading misinformation and learn the dosages, follow the FDA approved dosage 0.37IU's x (body-weight-in-kg) / 7 to find your daily dose and if you want to find your weekly dose then times it by 7 don't divide.

Now, onto the next.

"HGH only works if it's pharma grade :geek:!!!"

Is HGH some wizard potion that only the top wizard in Kazaksthan hired by pharma companies the only one in the world can make HGH? :feelsmage:
IF CHINESE LABS CAN MAKE EVERY OTHER STEROID WHAT MAKES YOU THINK THEY CAN'T MAKE HGH :ROFLMAO:
HGH isn't hard to make and therefore don't believe anyone who says it only works if it's pharma grade.

Now something to watch out for, is if it's dosed right and if it's actual HGH, because HGH isn't cheap so get a reliable high quality source, just to name one at random Deus Medicals is good and you can find it everywhere.

Reply under if I missed something and I'll answer in the replies.
STOP THE MISINFORMATION :lasereyes:
 
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the biggest misconception is thinking you'll gain any significant amount of height from it.

all the trials conducted on children that had actual deficiencies still ended up with them reaching a short adult height, they only had modest gains that they might've gotten anyway if they hadn't taken it.
 
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the biggest misconception is thinking you'll gain any significant amount of height from it.

all the trials conducted on children that had actual deficiencies still ended up with them reaching a short adult height, they only had modest gains that they might've gotten anyway if they hadn't taken it.
This^^^
 
the biggest misconception is thinking you'll gain any significant amount of height from it.

all the trials conducted on children that had actual deficiencies still ended up with them reaching a short adult height, they only had modest gains that they might've gotten anyway if they hadn't taken it.
paired with ai?
 
the biggest misconception is thinking you'll gain any significant amount of height from it.

all the trials conducted on children that had actual deficiencies still ended up with them reaching a short adult height, they only had modest gains that they might've gotten anyway if they hadn't taken it.
A friend of mine was always a really short kid in elementary/middle school, and very frail/weak. Injured himself doing normal shit like playing kickball at recess. In early high school he was something like 5’2-5’3 before he got medical intervention, they have him on expensive ass HGH injections nightly.

Now he’s close to my height, I’m 6’0. He told me the doctors said he may grow to 6’2-6’3. He might be a special case or it may be a genetic thing/specific pharmaceutical protocol that gave him such height gains. But I think You are right in that people with normally functioning endocrine systems aren’t going to become 6’4 Chad because they started pinning GH.

The best heightmaxx is really just instilling good habits from a young age and making sure you get enough quality food, sleep, and exercise when you’re in puberty. Being insecure about your height is a faggot trait anyways if you’re 5’7 or taller.
 
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the biggest misconception is thinking you'll gain any significant amount of height from it.

all the trials conducted on children that had actual deficiencies still ended up with them reaching a short adult height, they only had modest gains that they might've gotten anyway if they hadn't taken it.
Brutal :feelswhy:
 
I see alot of misinformation about HGH floating around this forum.

Insane idiots telling people to take 15IU's per day :ROFLMAO:
Idiots saying "HGH only works if it's pharma grade!" :ROFLMAO:
And so much other shit.

First of all, the approved dose for HGH by the FDA for Idiopathic Short Statue, will be referred as ISS, is 0.37 mg/kg/wk now explain to why the standard on this forum became "10IU's or Cope" fucking retards thinking they need more HGH then someone trying to catch up to their genetic height WITH A DEFICIENCY, meaning they are making up for the deficiency and adding on top of it.

Just to put it into perspective 10IU's would mean you weigh 200kg according to the FDA approved dosage for ISS. YOU DO NOT NEED THIS MUCH

I would say use the FDA dosage and if you really feel like "oh it's not enough man!!!:geek:" then add on 2IU's to the dosage and you'll be fine.

In my opinion, 5IU's would fit most people but use the dosage and make your dosage fit you.

In Pfizers Genotropin manual 3IU's per day is described as overdose and I hate to break it to you, but the difference on your height on 5IU's and 10IU's IS NOTHING :eek:

THE DIFFERENCE IN NOSE GAINS BETWEEN THE 2 IS A SIGNIFICANT INCREASE FOR 10IU'S :hnghn:


So stop spreading misinformation and learn the dosages, follow the FDA approved dosage 0.37IU's x (body-weight-in-kg) / 7 to find your daily dose and if you want to find your weekly dose then times it by 7 don't divide.

Now, onto the next.

"HGH only works if it's pharma grade :geek:!!!"

Is HGH some wizard potion that only the top wizard in Kazaksthan hired by pharma companies the only one in the world can make HGH? :feelsmage:
IF CHINESE LABS CAN MAKE EVERY OTHER STEROID WHAT MAKES YOU THINK THEY CAN'T MAKE HGH :ROFLMAO:
HGH isn't hard to make and therefore don't believe anyone who says it only works if it's pharma grade.

Now something to watch out for, is if it's dosed right and if it's actual HGH, because HGH isn't cheap so get a reliable high quality source, just to name one at random Deus Medicals is good and you can find it everywhere.

Reply under if I missed something and I'll answer in the replies.
STOP THE MISINFORMATION :lasereyes:
You are so fucking retarded you forgot to convert milligrams to IUs. Fuck yourself you autistic faggot.
 
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the biggest misconception is thinking you'll gain any significant amount of height from it.

all the trials conducted on children that had actual deficiencies still ended up with them reaching a short adult height, they only had modest gains that they might've gotten anyway if they hadn't taken it.
this is some high-quality written cope, thank you cro
Cro open air tour 2023 by sol vianini
 
more like honesty
1) Study 1: "Final Height of Children with Idiopathic Short Stature: GH Therapy's Effectiveness during Peri-puberty – A Multicenter Study"



This study investigates the effectiveness of growth hormone (GH) therapies in children with idiopathic short stature (ISS) without GH deficiency. It demonstrates that longer durations of GH treatment significantly increase final adult height. Particularly, the study suggests that girls tend to approach target height more closely than boys. The average treatment duration for the group treated for over two years was approximately 2.92 years, with this group showing the greatest improvement in final height compared to baseline. Emphasizing the need for individually tailored treatment under medical supervision, the study highlights the potential to maximize growth in ISS patients.



2) Study 2: BMC Pediatrics "Therapeutic Effects on Final Adult Height in Males with Idiopathic Short Stature and Advanced Bone Age"



This study evaluates different therapy regimens aimed at increasing final adult height in male adolescents with idiopathic short stature and advanced bone age. Combining GH with GnRHa (a hormone delaying puberty) or an aromatase inhibitor (AI, a medication blocking the conversion of androgens to estrogens) showed a significant improvement in final adult height compared to GH treatment alone. Particularly, the combination of GH and AI led to a surprising surpassing of the predicted adult height by an average of 11.67 cm. These findings underscore the potential of these combination therapies to maximize final height in ISS adolescents but require careful monitoring for potential side effects.



3) Study 3: BMJ: "Impact of Growth Hormone Therapy on Adult Height of Children with Idiopathic Short Stature: A Systematic Review"



This systematic review aimed to determine the influence of growth hormone therapy on adult height in children with idiopathic short stature. Children were included if they exhibited initial short stature, defined as height more than 2 standard deviations below the mean, and had no history of growth hormone therapy or comorbid conditions affecting growth. The primary efficacy measure was the difference in adult height between treated and untreated children. The analysis revealed that growth hormone treatments can lead to a significant increase in adult height, with a mean difference of over 0.9 standard deviation points (approximately 6 cm) considered a satisfactory response to therapy.



4) Study 4: International Journal of Pediatric Endocrinology: "A Randomized Pilot Trial of Growth Hormone with Anastrozole versus Growth Hormone Alone, Starting at the Very End of Puberty in Adolescents with Idiopathic Short Stature"



In this pilot study, the effects of combining growth hormone with anastrozole (an aromatase inhibitor) versus growth hormone alone were investigated in adolescents with idiopathic short stature who were at the very end of puberty. The study questioned the assumption that it might be too late to use growth hormones to achieve a significant increase in height in adolescents nearing the end of their growth period. The results indicated that the combination treatment could be effective in increasing final height, particularly when administered toward the end of the growth process. This study provides valuable insights into potential treatment approaches for adolescents with ISS who are nearing the end of their growth phase.



5) Study 5: “Randomized Trial of Aromatase Inhibitors, Growth Hormone, or Combination in Pubertal Boys with Idiopathic, Short Stature”



Children were given AI alone, GH alone, and AI + GH among their respective groups and were treated at age 14 for periods of 12- 36 months. When using AI alone they gained height at a rate of 7cm per year, GH alone 8.5cm per year, and AI + GH was 9.45cm per year. It would help if you also considered your current bone age, the older it is the less likely you are to come close to these gains. But if your bone age is 16-17, you could squeeze a few extra cm out before adulthood.



6) Study 6: “Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit”



Eighty eight of our children (68 males and 20 females) attained an adult height or near adult height of -0.71 SDS (0.74 SD) (95% CI, -0.87 to -0.55) with a benefit over untreated controls of 9.5 cm (7.4 to 11.6 cm) for males and 8.6 cm (6.7 to 10.5 cm) for females.

In the analysis of the subgroups, the adult height and adult height gain of children with non-familial short stature were significantly higher than of familial short stature. No difference was found in the cohorts with normal or delayed puberty in any of the subgroups, except between the non-familial short stature and familial short stature puberty cohorts. This has implications for the interpretation of the benefit of treatment in studies where the number of children with familial short stature in the controls or treated subjects is not known.

The treatment was safe. There were no significant adverse events. The IGF-1 values were essentially within the levels expected for the stages of puberty.
 
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1) Study 1: "Final Height of Children with Idiopathic Short Stature: GH Therapy's Effectiveness during Peri-puberty – A Multicenter Study"



This study investigates the effectiveness of growth hormone (GH) therapies in children with idiopathic short stature (ISS) without GH deficiency. It demonstrates that longer durations of GH treatment significantly increase final adult height. Particularly, the study suggests that girls tend to approach target height more closely than boys. The average treatment duration for the group treated for over two years was approximately 2.92 years, with this group showing the greatest improvement in final height compared to baseline. Emphasizing the need for individually tailored treatment under medical supervision, the study highlights the potential to maximize growth in ISS patients.



2) Study 2: BMC Pediatrics "Therapeutic Effects on Final Adult Height in Males with Idiopathic Short Stature and Advanced Bone Age"



This study evaluates different therapy regimens aimed at increasing final adult height in male adolescents with idiopathic short stature and advanced bone age. Combining GH with GnRHa (a hormone delaying puberty) or an aromatase inhibitor (AI, a medication blocking the conversion of androgens to estrogens) showed a significant improvement in final adult height compared to GH treatment alone. Particularly, the combination of GH and AI led to a surprising surpassing of the predicted adult height by an average of 11.67 cm. These findings underscore the potential of these combination therapies to maximize final height in ISS adolescents but require careful monitoring for potential side effects.



3) Study 3: BMJ: "Impact of Growth Hormone Therapy on Adult Height of Children with Idiopathic Short Stature: A Systematic Review"



This systematic review aimed to determine the influence of growth hormone therapy on adult height in children with idiopathic short stature. Children were included if they exhibited initial short stature, defined as height more than 2 standard deviations below the mean, and had no history of growth hormone therapy or comorbid conditions affecting growth. The primary efficacy measure was the difference in adult height between treated and untreated children. The analysis revealed that growth hormone treatments can lead to a significant increase in adult height, with a mean difference of over 0.9 standard deviation points (approximately 6 cm) considered a satisfactory response to therapy.



4) Study 4: International Journal of Pediatric Endocrinology: "A Randomized Pilot Trial of Growth Hormone with Anastrozole versus Growth Hormone Alone, Starting at the Very End of Puberty in Adolescents with Idiopathic Short Stature"



In this pilot study, the effects of combining growth hormone with anastrozole (an aromatase inhibitor) versus growth hormone alone were investigated in adolescents with idiopathic short stature who were at the very end of puberty. The study questioned the assumption that it might be too late to use growth hormones to achieve a significant increase in height in adolescents nearing the end of their growth period. The results indicated that the combination treatment could be effective in increasing final height, particularly when administered toward the end of the growth process. This study provides valuable insights into potential treatment approaches for adolescents with ISS who are nearing the end of their growth phase.



5) Study 5: “Randomized Trial of Aromatase Inhibitors, Growth Hormone, or Combination in Pubertal Boys with Idiopathic, Short Stature”



Children were given AI alone, GH alone, and AI + GH among their respective groups and were treated at age 14 for periods of 12- 36 months. When using AI alone they gained height at a rate of 7cm per year, GH alone 8.5cm per year, and AI + GH was 9.45cm per year. It would help if you also considered your current bone age, the older it is the less likely you are to come close to these gains. But if your bone age is 16-17, you could squeeze a few extra cm out before adulthood.



6) Study 6: “Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit”



Eighty eight of our children (68 males and 20 females) attained an adult height or near adult height of -0.71 SDS (0.74 SD) (95% CI, -0.87 to -0.55) with a benefit over untreated controls of 9.5 cm (7.4 to 11.6 cm) for males and 8.6 cm (6.7 to 10.5 cm) for females.

In the analysis of the subgroups, the adult height and adult height gain of children with non-familial short stature were significantly higher than of familial short stature. No difference was found in the cohorts with normal or delayed puberty in any of the subgroups, except between the non-familial short stature and familial short stature puberty cohorts. This has implications for the interpretation of the benefit of treatment in studies where the number of children with familial short stature in the controls or treated subjects is not known.

The treatment was safe. There were no significant adverse events. The IGF-1 values were essentially within the levels expected for the stages of puberty.
ok i wont read all this but, we don't have ISS we have normal GH amounts, so therefore we cannot expect to grow insane amount like people with ISS, when you have ISS and you get administered GH you're basically catching up to what you should've been, if you have normal GH lvls then you should grow normally and adding more GH is only gonna be a boost, your body has a limit eventually, of how much you can intake and use and your height limit
 
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Is it possible to get a horse face because of growth hormone?
 
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Is it possible to get a horse face because of growth hormone?
it’ll just grow what ur current growth pattern is so if u already had horse face you’ll have more horse face
 
it’ll just grow what ur current growth pattern is so if u already had horse face you’ll have more horse face
Bcs of your thread, I stopped using hgh because I think it will change my face and fuck my proportions
 
ok i wont read all this but, we don't have ISS we have normal GH amounts, so therefore we cannot expect to grow insane amount like people with ISS, when you have ISS and you get administered GH you're basically catching up to what you should've been, if you have normal GH lvls then you should grow normally and adding more GH is only gonna be a boost, your body has a limit eventually, of how much you can intake and use and your height limit
retard, idiopathic short stature is when a child has normal gh levels however is still short asf, gh deficency is NOT iss.
 
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1) Study 1: "Final Height of Children with Idiopathic Short Stature: GH Therapy's Effectiveness during Peri-puberty – A Multicenter Study"



This study investigates the effectiveness of growth hormone (GH) therapies in children with idiopathic short stature (ISS) without GH deficiency. It demonstrates that longer durations of GH treatment significantly increase final adult height. Particularly, the study suggests that girls tend to approach target height more closely than boys. The average treatment duration for the group treated for over two years was approximately 2.92 years, with this group showing the greatest improvement in final height compared to baseline. Emphasizing the need for individually tailored treatment under medical supervision, the study highlights the potential to maximize growth in ISS patients.



2) Study 2: BMC Pediatrics "Therapeutic Effects on Final Adult Height in Males with Idiopathic Short Stature and Advanced Bone Age"



This study evaluates different therapy regimens aimed at increasing final adult height in male adolescents with idiopathic short stature and advanced bone age. Combining GH with GnRHa (a hormone delaying puberty) or an aromatase inhibitor (AI, a medication blocking the conversion of androgens to estrogens) showed a significant improvement in final adult height compared to GH treatment alone. Particularly, the combination of GH and AI led to a surprising surpassing of the predicted adult height by an average of 11.67 cm. These findings underscore the potential of these combination therapies to maximize final height in ISS adolescents but require careful monitoring for potential side effects.



3) Study 3: BMJ: "Impact of Growth Hormone Therapy on Adult Height of Children with Idiopathic Short Stature: A Systematic Review"



This systematic review aimed to determine the influence of growth hormone therapy on adult height in children with idiopathic short stature. Children were included if they exhibited initial short stature, defined as height more than 2 standard deviations below the mean, and had no history of growth hormone therapy or comorbid conditions affecting growth. The primary efficacy measure was the difference in adult height between treated and untreated children. The analysis revealed that growth hormone treatments can lead to a significant increase in adult height, with a mean difference of over 0.9 standard deviation points (approximately 6 cm) considered a satisfactory response to therapy.



4) Study 4: International Journal of Pediatric Endocrinology: "A Randomized Pilot Trial of Growth Hormone with Anastrozole versus Growth Hormone Alone, Starting at the Very End of Puberty in Adolescents with Idiopathic Short Stature"



In this pilot study, the effects of combining growth hormone with anastrozole (an aromatase inhibitor) versus growth hormone alone were investigated in adolescents with idiopathic short stature who were at the very end of puberty. The study questioned the assumption that it might be too late to use growth hormones to achieve a significant increase in height in adolescents nearing the end of their growth period. The results indicated that the combination treatment could be effective in increasing final height, particularly when administered toward the end of the growth process. This study provides valuable insights into potential treatment approaches for adolescents with ISS who are nearing the end of their growth phase.



5) Study 5: “Randomized Trial of Aromatase Inhibitors, Growth Hormone, or Combination in Pubertal Boys with Idiopathic, Short Stature”



Children were given AI alone, GH alone, and AI + GH among their respective groups and were treated at age 14 for periods of 12- 36 months. When using AI alone they gained height at a rate of 7cm per year, GH alone 8.5cm per year, and AI + GH was 9.45cm per year. It would help if you also considered your current bone age, the older it is the less likely you are to come close to these gains. But if your bone age is 16-17, you could squeeze a few extra cm out before adulthood.



6) Study 6: “Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit”



Eighty eight of our children (68 males and 20 females) attained an adult height or near adult height of -0.71 SDS (0.74 SD) (95% CI, -0.87 to -0.55) with a benefit over untreated controls of 9.5 cm (7.4 to 11.6 cm) for males and 8.6 cm (6.7 to 10.5 cm) for females.

In the analysis of the subgroups, the adult height and adult height gain of children with non-familial short stature were significantly higher than of familial short stature. No difference was found in the cohorts with normal or delayed puberty in any of the subgroups, except between the non-familial short stature and familial short stature puberty cohorts. This has implications for the interpretation of the benefit of treatment in studies where the number of children with familial short stature in the controls or treated subjects is not known.

The treatment was safe. There were no significant adverse events. The IGF-1 values were essentially within the levels expected for the stages of puberty.
Thanks for posting this. I don't know wtf is going on with the misinformation on those forum.

retard, idiopathic short stature is when a child has normal gh levels however is still short asf, gh deficency is NOT iss.
^ this. OP proved to be a retard who hasn't read a single study when he made that comment about ISS.
 
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ok i wont read all this but, we don't have ISS we have normal GH amounts, so therefore we cannot expect to grow insane amount like people with ISS, when you have ISS and you get administered GH you're basically catching up to what you should've been, if you have normal GH lvls then you should grow normally and adding more GH is only gonna be a boost, your body has a limit eventually, of how much you can intake and use and your height limit
ISS doesn't mean you have growth hormone deficiency

It just means you are shorter than a certain threshold in said population/local group.
1) Study 1: "Final Height of Children with Idiopathic Short Stature: GH Therapy's Effectiveness during Peri-puberty – A Multicenter Study"

...
Thank you for dispelling the cope that HGH is cope.

It can improve one's final height, though it won't take a 5ft6 manlet to 6ft4, a few inches is amazing results. Life changing for someone to grow to 5ft8 if he was destined to be 5ft6.
the biggest misconception is thinking you'll gain any significant amount of height from it.

all the trials conducted on children that had actual deficiencies still ended up with them reaching a short adult height, they only had modest gains that they might've gotten anyway if they hadn't taken it.
The problem is how many users here even have open growth plates and are able to source.

And even if they could, are they young enough even to reap maximum benefits? Realistically risking many other sides while having the possibility of only growing barely or even not at all.
Now something to watch out for, is if it's dosed right and if it's actual HGH, because HGH isn't cheap so get a reliable high quality source, just to name one at random Deus Medicals is good and you can find it everywhere.
As far as I've seen on other online posts people are just dosing it at flat 8 IU's?

It should be dosed on bodyweight no?
 
As far as I've seen on other online posts people are just dosing it at flat 8 IU's?

It should be dosed on bodyweight no?
yes there are dose for different kilos/heights its 5 iu for me
But when I dosed 6 units, I reduced it to 4 because I noticed a change in my jaw and teeth.
 
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I see alot of misinformation about HGH floating around this forum.

Insane idiots telling people to take 15IU's per day :ROFLMAO:
Idiots saying "HGH only works if it's pharma grade!" :ROFLMAO:
And so much other shit.

First of all, the approved dose for HGH by the FDA for Idiopathic Short Statue, will be referred as ISS, is 0.37 mg/kg/wk now explain to why the standard on this forum became "10IU's or Cope" fucking retards thinking they need more HGH then someone trying to catch up to their genetic height WITH A DEFICIENCY, meaning they are making up for the deficiency and adding on top of it.

Just to put it into perspective 10IU's would mean you weigh 200kg according to the FDA approved dosage for ISS. YOU DO NOT NEED THIS MUCH

I would say use the FDA dosage and if you really feel like "oh it's not enough man!!!:geek:" then add on 2IU's to the dosage and you'll be fine.

In my opinion, 5IU's would fit most people but use the dosage and make your dosage fit you.

In Pfizers Genotropin manual 3IU's per day is described as overdose and I hate to break it to you, but the difference on your height on 5IU's and 10IU's IS NOTHING :eek:

THE DIFFERENCE IN NOSE GAINS BETWEEN THE 2 IS A SIGNIFICANT INCREASE FOR 10IU'S :hnghn:


So stop spreading misinformation and learn the dosages, follow the FDA approved dosage 0.37IU's x (body-weight-in-kg) / 7 to find your daily dose and if you want to find your weekly dose then times it by 7 don't divide.

Now, onto the next.

"HGH only works if it's pharma grade :geek:!!!"

Is HGH some wizard potion that only the top wizard in Kazaksthan hired by pharma companies the only one in the world can make HGH? :feelsmage:
IF CHINESE LABS CAN MAKE EVERY OTHER STEROID WHAT MAKES YOU THINK THEY CAN'T MAKE HGH :ROFLMAO:
HGH isn't hard to make and therefore don't believe anyone who says it only works if it's pharma grade.

Now something to watch out for, is if it's dosed right and if it's actual HGH, because HGH isn't cheap so get a reliable high quality source, just to name one at random Deus Medicals is good and you can find it everywhere.

Reply under if I missed something and I'll answer in the replies.
STOP THE MISINFORMATION :lasereyes:
No shit there is kg to dose converters and its literally the first thing u see when i search hgh doses, like thx for shitty thread
 
No shit there is kg to dose converters and its literally the first thing u see when i search hgh doses, like thx for shitty thread
jk im a hater 😜
 
the biggest misconception is thinking you'll gain any significant amount of height from it.

all the trials conducted on children that had actual deficiencies still ended up with them reaching a short adult height, they only had modest gains that they might've gotten anyway if they hadn't taken it.
Diy shit poster with no knowledge on hormones talking about hormones “muh but orc joined before u” and then that nigga says this
 
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1) Study 1: "Final Height of Children with Idiopathic Short Stature: GH Therapy's Effectiveness during Peri-puberty – A Multicenter Study"



This study investigates the effectiveness of growth hormone (GH) therapies in children with idiopathic short stature (ISS) without GH deficiency. It demonstrates that longer durations of GH treatment significantly increase final adult height. Particularly, the study suggests that girls tend to approach target height more closely than boys. The average treatment duration for the group treated for over two years was approximately 2.92 years, with this group showing the greatest improvement in final height compared to baseline. Emphasizing the need for individually tailored treatment under medical supervision, the study highlights the potential to maximize growth in ISS patients.



2) Study 2: BMC Pediatrics "Therapeutic Effects on Final Adult Height in Males with Idiopathic Short Stature and Advanced Bone Age"



This study evaluates different therapy regimens aimed at increasing final adult height in male adolescents with idiopathic short stature and advanced bone age. Combining GH with GnRHa (a hormone delaying puberty) or an aromatase inhibitor (AI, a medication blocking the conversion of androgens to estrogens) showed a significant improvement in final adult height compared to GH treatment alone. Particularly, the combination of GH and AI led to a surprising surpassing of the predicted adult height by an average of 11.67 cm. These findings underscore the potential of these combination therapies to maximize final height in ISS adolescents but require careful monitoring for potential side effects.



3) Study 3: BMJ: "Impact of Growth Hormone Therapy on Adult Height of Children with Idiopathic Short Stature: A Systematic Review"



This systematic review aimed to determine the influence of growth hormone therapy on adult height in children with idiopathic short stature. Children were included if they exhibited initial short stature, defined as height more than 2 standard deviations below the mean, and had no history of growth hormone therapy or comorbid conditions affecting growth. The primary efficacy measure was the difference in adult height between treated and untreated children. The analysis revealed that growth hormone treatments can lead to a significant increase in adult height, with a mean difference of over 0.9 standard deviation points (approximately 6 cm) considered a satisfactory response to therapy.



4) Study 4: International Journal of Pediatric Endocrinology: "A Randomized Pilot Trial of Growth Hormone with Anastrozole versus Growth Hormone Alone, Starting at the Very End of Puberty in Adolescents with Idiopathic Short Stature"



In this pilot study, the effects of combining growth hormone with anastrozole (an aromatase inhibitor) versus growth hormone alone were investigated in adolescents with idiopathic short stature who were at the very end of puberty. The study questioned the assumption that it might be too late to use growth hormones to achieve a significant increase in height in adolescents nearing the end of their growth period. The results indicated that the combination treatment could be effective in increasing final height, particularly when administered toward the end of the growth process. This study provides valuable insights into potential treatment approaches for adolescents with ISS who are nearing the end of their growth phase.



5) Study 5: “Randomized Trial of Aromatase Inhibitors, Growth Hormone, or Combination in Pubertal Boys with Idiopathic, Short Stature”



Children were given AI alone, GH alone, and AI + GH among their respective groups and were treated at age 14 for periods of 12- 36 months. When using AI alone they gained height at a rate of 7cm per year, GH alone 8.5cm per year, and AI + GH was 9.45cm per year. It would help if you also considered your current bone age, the older it is the less likely you are to come close to these gains. But if your bone age is 16-17, you could squeeze a few extra cm out before adulthood.



6) Study 6: “Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit”



Eighty eight of our children (68 males and 20 females) attained an adult height or near adult height of -0.71 SDS (0.74 SD) (95% CI, -0.87 to -0.55) with a benefit over untreated controls of 9.5 cm (7.4 to 11.6 cm) for males and 8.6 cm (6.7 to 10.5 cm) for females.

In the analysis of the subgroups, the adult height and adult height gain of children with non-familial short stature were significantly higher than of familial short stature. No difference was found in the cohorts with normal or delayed puberty in any of the subgroups, except between the non-familial short stature and familial short stature puberty cohorts. This has implications for the interpretation of the benefit of treatment in studies where the number of children with familial short stature in the controls or treated subjects is not known.

The treatment was safe. There were no significant adverse events. The IGF-1 values were essentially within the levels expected for the stages of puberty.
id read this but its 3am 😔
 
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how many mcg 5 iu is?
 

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