COMPLETE PEPTIDE REFERENCE GUIDE: DOSING & PROTOCOLS

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COMPLETE PEPTIDE REFERENCE GUIDE: DOSING & PROTOCOLS​

I. Nootropics & Neuroprotection​

Peptides designed to enhance cognitive function, neurogenesis, and mood stabilization.

Peptide	Primary Benefit	Standard Protocol	Key Evidence
Semax	Focus & Mental Clarity	200–600 mcg (Intranasal)	Increases BDNF levels; acts as a melanocortin derivative for neuro-restoration.
Selank	Anxiety & Stress	250–500 mcg (Intranasal)	Mimics Tuftsin; modulates GABA and enkephalins without sedation.
Cerebrolysin	Neuro-Repair	5 mL (IM/IV) daily for 5-day cycles	Mixture of porcine peptides; used for TBI and vascular dementia recovery.
Pinealon	Circadian Rhythm	5–10 mg (Oral/SQ)	Targets the pineal gland; improves sleep-wake cycles and DNA repair.

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II. Tissue Repair & Recovery​

The "gold standard" for healing connective tissue, muscle, and reducing systemic inflammation.

Peptide	Primary Benefit	Standard Protocol	Key Evidence
BPC-157	Systemic Healing	250–500 mcg (SQ/Oral) 1-2x daily	Angiogenic; promotes fibroblast activity in tendons and gut lining.
TB-500	Flexibility & Repair	2.5–5 mg (SQ) 2x weekly	Actin-sequestering; promotes cell migration to injury sites.
KPV	Inflammation	200–500 mcg (SQ/Oral)	Potent anti-inflammatory tripeptide; targets Mast Cell Activation (MCAS).

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III. Metabolic & Mitochondrial Health​

Focuses on cellular energy (ATP), fat oxidation, and mitochondrial biogenesis.

Peptide	Primary Benefit	Standard Protocol	Key Evidence
SS-31	Mitochondrial Repair	10–40 mg (SQ) daily	Targets cardiolipin in the inner mitochondrial membrane; reduces ROS.
MOTS-c	Exercise Mimetic	5 mg (SQ) 3x weekly	Regulates glucose metabolism via the AMPK pathway.
5-amino-1MQ	NAD+ Preservation	50 mg (Oral) 1-3x daily	Inhibits NNMT; prevents the depletion of NAD+ stores and improves metabolism.
NAD+	Energy & Longevity	100–500 mg (SQ/IV)	Coenzyme critical for redox reactions and sirtuin activation.

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IV. Aesthetics, Hair & Skin​

Peptides focused on collagen synthesis, hair growth, and pigmentation.

Peptide	Primary Benefit	Standard Protocol	Key Evidence
GHK-Cu	Skin & Collagen	1–2 mg (SQ) or 1-2% Topical	Remodels the extracellular matrix; powerful wound healing signal.
AHK-Cu	Hair Growth	1-5% Topical	Stimulates hair follicle dermal papilla cells; inhibits follicular apoptosis.
MT-1	Skin Pigmentation	500 mcg – 1 mg (SQ) daily	MC1R agonist; provides photoprotection and tanning with fewer side effects than MT-2.
Snap-8	Anti-Wrinkle	5-10% Topical	"Botox in a jar"; inhibits muscle contraction via SNARE complex modulation.

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V. Specialized & Hormonal Support​

Peptides for immune modulation, sleep, and GH secretion.

Peptide	Primary Benefit	Standard Protocol	Key Evidence
Thymosin Alpha-1	Immune Modulation	1.5 mg (SQ) 2x weekly	Increases T-cell maturation; used for chronic infections and immune lag.
DSIP	Deep Sleep	100 mcg (SQ) before bed	Modulates delta-wave sleep; effective for chronic insomnia.
Epithalon	Telomere Length	5–10 mg (SQ) daily (10-day cycle)	Increases telomerase activity; regulates pineal function.
Ipamorelin	GH Secretagogue	100–300 mcg (SQ) at night	Stimulates GH pulse without increasing hunger (Ghrelin) or Cortisol.

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PROVEN STACKING STRATEGIES​

1. The "Wolverine" Healing Stack​

• BPC-157: 250 mcg (SQ) twice daily.
• TB-500: 2.5 mg (SQ) twice weekly.
• Rationale: BPC-157 initiates the repair of the extracellular matrix, while TB-500 recruits progenitor cells to the site of injury.

2. The Mitochondrial Rescuer​

• SS-31: 20 mg (SQ) daily (20-day primer).
• MOTS-c: 5 mg (SQ) three times weekly (following SS-31).
• NAD+: 100 mg (SQ) daily.
• Rationale: SS-31 fixes the mitochondrial structure first, allowing NAD+ and MOTS-c to operate more efficiently.

3. The Brain & Focus Stack​

• Semax: 300 mcg (Intranasal) morning.
• Cerebrolysin: 5 mL (IM) five days on, two days off.
• Rationale: Combines immediate BDNF/ACTH signaling (Semax) with the long-term structural repair factors in Cerebrolysin.

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[!NOTE]
Safety & Administration: Most peptides are reconstituted with Bacteriostatic Water. Always use a fresh insulin syringe for each injection. Store all reconstituted peptides in the refrigerator to maintain stability.

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