COOMERS BTFO, COOMERS GET DESTROYED BY BIG BLACK ESSAY [HD] [PREMIUM]

big black essay cucked by didn't read
 
Lol
Get destroyed you fucking idiot
Stop recommending shit to kids if u cant even read a study you utter subhuman
Kys faggot
I read both studies. If your point is that they were done in rats, you're invalid, because most studies are done on rats. Male rats have significantly similar endocrinology as male humans.

serum estradiol levels remained unchanged 24 h after one ejaculation or mating to satiety. These data suggest a relationship between sexual activity and an increase in the expression of ERalpha in specific brain areas, independently of estradiol levels in systemic circulation.

The expression of ERalpha increased in certain areas of the brain despite stagnate estradiol levels post ejaculation, again, the same thing applies to brain-specific androgen receptors, but on the opposite side of the spectrum, they downregulated, despite a lack of steroidal fluctuation. Your brain can't comprehend such things, don't worry about it.
 
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Atleast im not recommending alibaba hgh to kids
this is the same outdated conjecture that strike used to expel upon me. I've refuted the reliability of products from Alibaba, my stance has since changed, I'm not responsible for some retard stumbling across an old thread of mine and deciding to inject rat piss. Although in saying that, strike is objectively responsible to the outcome of his followers, because he actively pushes for dangerous drugs whilst simultaneously refering to them as 'lab rats'.
 
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this is the same outdated conjecture that strike used to expel upon me. I've refuted the reliability of products from Alibaba, my stance has since changed, I'm not responsible for some retard stumbling across an old thread of mine and deciding to inject rat piss. Although in saying that, strike is objectively responsible to the outcome of his followers, because he actively pushes for dangerous drugs whilst simultaneously refering to them as 'lab rats'.
Bruhh is it acc fake because I’ve ordered 3 months worth a couple days ago
 
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I read both studies. If your point is that they were done in rats, you're invalid, because most studies are done on rats. Male rats have significantly similar endocrinology as male humans.



The expression of ERalpha increased in certain areas of the brain despite stagnate estradiol levels post ejaculation, again, the same thing applies to brain-specific androgen receptors, but on the opposite side of the spectrum, they downregulated, despite a lack of steroidal fluctuation. Your brain can't comprehend such things, don't worry about it.
"specific brain areas,"
if u think that it nofap will help you build more muscle, help you develop secondary sexual characteristics
then u are wrong.
think again.
 
this is the same outdated conjecture that strike used to expel upon me. I've refuted the reliability of products from Alibaba, my stance has since changed, I'm not responsible for some retard stumbling across an old thread of mine and deciding to inject rat piss. Although in saying that, strike is objectively responsible to the outcome of his followers, because he actively pushes for dangerous drugs whilst simultaneously refering to them as 'lab rats'.
I wont read your bitchass essay stoo recommending drugs to kids idiot
 
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Bruhh is it acc fake because I’ve ordered 3 months worth a couple days ago
Unfortunately yes. All growth hormone is dangerous and useless.
 
A lot of high iq threads like these are not in the best of the best section
 
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"specific brain areas,"
if u think that it nofap will help you build more muscle, help you develop secondary sexual characteristics
then u are wrong.
think again.
Did I mention once that I agreed with the retards' stance on nofap? holy fuck you're an imbecile.
 
Buddy, next time, if you're going to ad-hominem the hell out of me, at least have some sort of valid argument to justify the belligerent behavior. I don't know why I even bother conversing with a monkey of the likes.
Lmao shut the fuck up
You are bitter as shit for no other reason then being a subhuman.
 
Androgen Receptors Density doesnt increase at all
I was referring to this post, in which I linked studies to. It was never about growing bigger muscles you fucking moron.
 
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I was referring to this post, in which I linked studies to. It was never about growing bigger muscles you fucking moron.
Yes
In the brain you fucking moron
Whats ur stance on nofap lol
You seem to change your opinion about everything lul
 
Unfortunately yes. All growth hormone is dangerous and useless.
I’m going to risk it, but what are the dangers I will be facing?
 
I can't believe this thread is still going on.

You coomers need to open your eyes and stop beating your meat, blindly assuming that it is a normal thing to do.
 
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In the brain you fucking moron
Please don't regurgitate my insults back at me, use your brain.
Whats ur stance on nofap lol
Depends on why you're doing it, I never once supported the notion that it supposedly increased muscle mass or masculine energy, all of that crap is pseudoscience junk.
You seem to change your opinion about everything lul
Barely, I haven't talked about nofap at all. Just keep cooming even though there is definitive evidence that it affects the brain. Increases prolactin which directly antagonizes dopamine, upregulates estradiol receptors, and downregulates androgen receptors in the brain.

I'm talking to a brick wall with a set of eyes and a dribbling mouth, there's no point conversing with you.
 
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I’m going to risk it, but what are the dangers I will be facing?
Don't do it. It's most likely not even growth hormone, probably a cheaper peptide like hexarelin or recombinant GHRH. I'm not going to dabble into the dangers, but growth hormone is a massive cope, and a dangerous one at that.

the pharmaceutical level recombinant growth hormone is a virtue for the rich, not for the likes of us.
 
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Please don't regurgitate my insults back at me, use your brain.

Depends on why you're doing it, I never once supported the notion that it supposedly increased muscle mass or masculine energy, all of that crap is pseudoscience junk.

Barely, I haven't talked about nofap at all. Just keep cooming even though there is definitive evidence that it affects the brain. Increases prolactin which directly antagonizes dopamine, upregulates estradiol receptors, and downregulates androgen receptors in the brain.

I'm talking to a brick wall with a set of eyes and a dribbling mouth, there's no point conversing with you.
Atleast you admitted it little boy
It wont have any effect on your body.
Idk why you posted those two research like its something groundbreaking lul
If u read the thread i said "no evidence at all"
To the hormones/andogen cope in the body.
So idk how im supposed to know what u mean by that two study
 
" Days 1-5 testosterone levels steadily increase, "


COMMERS HAD HIGHER TESTOSTERONE AT DAY 2-4 THEN NOFAPPERS
ITS OVER FOR YOU
YOU CANT EVER READ A STUDY
didn't read but I'm going to choose to believe this guy
 
It wont have any effect on your body.
the brain is the most important organ, it's apart of the body, beyond brainlet tier reply.
Idk why you posted those two research like its something groundbreaking lul
didn't suggest it was groundbreaking, all I did was reply to your conjectured post with two studies proving that both steroidal receptors downregulate/upregulate without fluctuations in steroidal hormone levels.
If u read the thread i said "no evidence at all"
You originally said, "Androgen Receptors Density doesn't increase at all". I'm refuting this statement through posting studies that prove that ejaculation actually downregulates androgen receptor density whilst simultaneously increasing the expression of ERalpha, both of which aren't desirable biological functions. There's your evidence. I don't know why you're still quoting me at this point, it's extremely egotistical and pathetic, don't worry, it's not the first time I've had you stop replying to me in an argument, after a couple of ad-hominems you eventually back down.
 
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the brain is the most important organ, it's apart of the body, beyond brainlet tier reply.

didn't suggest it was groundbreaking, all I did was reply to your conjectured post with two studies proving that both steroidal receptors downregulate/upregulate without fluctuations in steroidal hormone levels.

You originally said, "Androgen Receptors Density doesn't increase at all". I'm refuting this statement through posting studies that prove that ejaculation actually downregulates androgen receptor density whilst simultaneously increasing the expression of ERalpha, both of which aren't desirable biological functions. There's your evidence. I don't know why you're still quoting me at this point, it's extremely egotistical and pathetic, don't worry, it's not the first time I've had you stop replying to me in an argument, after a couple of ad-hominems you eventually back down.
You are such a fucking manlet faggot its unbeleivable
"It wont have any effect on your body.
the brain is the most important organ, it's apart of the body, beyond brainlet tier reply. "
single digit iq reply
i meant by developing sexual dimoprhic characteristics, or muscle building
its obvious by now that u are a dyslexic autist dog
kill urself.

" didn't suggest it was groundbreaking, all I did was reply to your conjectured post with two studies proving that both steroidal receptors downregulate/upregulate without fluctuations in steroidal hormone levels. "
you said "kill yourself" lul
You didnt even mention it that its in the brain, nobody argued that you fucking idiot
bet you didnt even read the study first
read the original thread low iq retard, such a brainlet faggot.


f u read the thread i said "no evidence at all"
You originally said, "Androgen Receptors Density doesn't increase at all". I'm refuting this statement through posting studies that prove that ejaculation actually downregulates androgen receptor density whilst simultaneously increasing the expression of ERalpha, both of which aren't desirable biological functions. There's your evidence. I don't know why you're still quoting me at this point, it's extremely egotistical and pathetic, don't worry, it's not the first time I've had you stop replying to me in an argument, after a couple of ad-hominems you eventually back down.
again you are a bitter faggot manlet
i already said that it downregulates in the brain,but it wont have any effect that the OP said you fucking brainlet
ironically you ve stopped replying to me in the last thread aswell
because you are suggesting ali baba hgh to kids you fucking dwarf low degenerate
stop acting like a biologist while you dont know shit you fucking idiot.
slit ur wrists.
 
I'm not interested in the benefits of nofap.

I don't care whether it will make my face better or not.

But fapping isn't normal, it's cucked. Life on nofap mogs. Not fapping > fapping.
Fapping makes me feel like shit tbh.
 
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the brain is the most important organ, it's apart of the body, beyond brainlet tier reply.

didn't suggest it was groundbreaking, all I did was reply to your conjectured post with two studies proving that both steroidal receptors downregulate/upregulate without fluctuations in steroidal hormone levels.

You originally said, "Androgen Receptors Density doesn't increase at all". I'm refuting this statement through posting studies that prove that ejaculation actually downregulates androgen receptor density whilst simultaneously increasing the expression of ERalpha, both of which aren't desirable biological functions. There's your evidence. I don't know why you're still quoting me at this point, it's extremely egotistical and pathetic, don't worry, it's not the first time I've had you stop replying to me in an argument, after a couple of ad-hominems you eventually back down.
and most importantly
stop trying to act tough when ur a skinny shrimp little beta
 
stop trying to act tough when ur a skinny shrimp little beta
I'd drop you on your neck in real life, also didn't read the crap above. Keep barking though. Reminder you called yourself low IQ, i didn't even need to call you it.

1596710301465
 
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I'd drop you on your neck in real life, also didn't read the crap above. Keep barking though. Reminder you called yourself low IQ, i didn't even need to call you it.

View attachment 570066
Nice you cant even read skinny nct twink
i already said it that strike destroyed you fucking subhuman kys
", also didn't read the crap above."
You are already on a suicide watch
i will get ur retarded pics soon it will be fun
i heard from others that ur an ugly twink i will laugh hard you faggot
 
Nice you cant even read skinny nct twink
i already said it that strike destroyed you fucking subhuman kys
", also didn't read the crap above."
You are already on a suicide watch
i will get ur retarded pics soon it will be fun
i heard from others that ur an ugly twink i will laugh hard you faggot
didn't read, can't stand looking at your foundationless ad hominem ridden paragraphs. Make a useful thread, you've got an orange name tag yet you've never actually contributed anything to this forum.

1596710643084
 
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didn't read, can't stand looking at your foundationless ad hominem ridden paragraphs. Make a useful thread, you've got an orange name tag yet you've never actually contributed anything to this forum.

View attachment 570071
Your only contribution is MAKING KIDS TAKE ALIBABA RAT PISS U UTTER SUBHUMAN JFL
 
i will get ur retarded pics soon it will be fun
also, those pictures were a LARP, I'm sure you're referring to the titbot/5ft8paki scandal.

only a couple of users have seen my face, and they've all left the forum. Feel free to reply again with a barrage of crap, I'm done talking to a brick wall.
 
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also, those pictures were a LARP, I'm sure you're referring to the titbot/5ft8paki scandal.

only a couple of users have seen my face, and they've all left the forum. Feel free to reply again with a barrage of crap, I'm done talking to a brick wall.
" I bought off of Alibaba and got legit good growth hormone. " -dyorotics2
Wow you are a legti DEGENERATE
kill urself low iq subhuman
fucking ugly twink
 
" I bought off of Alibaba and got legit good growth hormone. " -dyorotics2
Wow you are a legti DEGENERATE
kill urself low iq subhuman
fucking ugly twink
got yourself ignored. Not like it matters, none of your posts are actually worth reading. I can't believe how vulgar and barbaric you are, I'd drop you on your neck within seconds, that's the irony behind all this beligerant posting. Seeya.

1596710944868
 
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got yourself ignored. Not like it matters, none of your posts are actually worth reading. I can't believe how vulgar and barbaric you are, I'd drop you on your neck within seconds, that's the irony behind all this beligerant posting. Seeya.

View attachment 570075
lol GET BULLIED YOU NCT TWINK
LONG MIDFACE SUBHUMAN WEAK BETA
I WILL HAVE YOUR SUBHUMAN PICS SOON IT WILL BE FUNNY AS HELL
 
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Fapping makes me feel like shit tbh.
Yeah bro. Let's be honest to ourselves... life as a kid (when we didn't fap) was much more better. I used to feel very clean and pure back then.
 
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O
Semen retention is critical for the sexually dimorphic traits of males to manifest. Without it you become an undifferentiated ungendered pawn. Sexual dimorphism is primarily expressed via differing levels of testosterone and estradiol (estrogen in its biologically active form). The final controller of ALL hormone expression is the brain, and specifically the hypothalamus. The only intervention that works to increase testosterone is changing your brain structure. Masturbation is proven to do this.
Before we can even get to semen retention, we have to understand how your body works, and the critically misunderstood roles that hormones play.

Why Testosterone? Most of you, I'm sure, are already convinced about the beneficial effects of testosterone in men, but I want to give a brief overview of things you probably don't know about it. Testosterone increases sociability. It increases connection to and participation in your milieu, this is true for both men and women. For women, this typically manifests as slutty behavior and ultimately ends up as cuckoldry, women with higher testosterone have sluttier faces. They also have greater sexual arousal levels: https://ww.ncbi.nlm.nih.gov/pubmed/10665617 For men however, testosterone decrease the incidence of lying and they are more cooperative with other men. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468628 Men with high testosterone are fascistic ideal. They build, cooperate, and create civilization. Men with high testosterone are more driven to find not only mates, but to do all things. Testosterone receptors in the brain don't differentiate drive for sex from any other drive (that differentiation does occur, but requires other chemical receptors to be activated as well).

The Hypothalamus is King Androgen/Testosterone boosting supplements don't work unless you are supplementing androgens higher than 100% of your baseline test production. To understand why this is, you have to first understand the HP axes, and specifically the HPG axis. The hypothalamus acts as a prime regulator for almost all hormones related to growth, sex, and homeostasis. Hypothalamus notices an increased level of testosterone? It stops producing GnRH. GnRH is a signal to your pituitary gland to make FSH (follicle-stimulating hormone) and LH (luteinizing hormone); these signal the gonads in men to create sperm and testosterone respectively (in women's gonads these signal menstruation and estrogen). So at all times your hypothalamus is listening to the levels of sex hormones, and is only releasing enough GnRH to keep them at what it believes to be the proper homeostasis. This is why only highly potent anabolic steroids are really the only things which appear to have a phenotypic response in humans. They overpower even the hypothalamus's ability to regulate testosterone. So when taking anabolic steroids your level of GnRH is basically zero. There is no activity on the HPG axis and it permanently changes your hypothalamus to produce less GnRH, and hence why you hear stories of anabolic steroids shrinking your balls and causing infertility. So to maximize your GnRH you need to maximize the hormones which stimulate its production and minimize the ones that inhibit it. There are many hormones which either stimulate or inhibit the production of GnRH, we will get into why fapping is one of the worst things you can do if you want to maximize GnRH next.

There are several other axes of the hypothalamus which should also be mentioned. The hypothalamic—pituitary—prolactin axis (HPP) is responsible for lactation and mammary growth in females, but it is also present in males. It is not directly self-inhibiting like the HPG axis, but instead is inhibited by dopamine (this will seem contradictory at first, but is extremely important to understanding the dangers of masturbation). The main thing for now you should know is that excess prolactin causes typically feminine traits in men. The primary stimulating factor of the HPP axis is estrogen. Remember this is the only axis which isn't a direct feedback loop! More estrogen will always mean more prolactin. Finally, the higher your prolactin is, the lower GnRH output will be, which means the lower testosterone will be in males. The HPS axis has the ultimate byproduct of IGF-1, which is the most critical signal for muscle growth. HPS axis is stimulated by testosterone (via blunting the inhibitory effects of GH in the feedback loop).

Masturbation and Hormones Now to put it all together. Orgasm elevates prolactin massively. Prolactin causes a neurological effect of having little to no sexual desire, hence why you temporarily lose interest in the porn you watch after ejaculation. Now recall the previous section: Prolactin tells the hypothalamus to lower GnRH; GnRH stimulates production of sperm and testosterone; testosterone increases masculine traits and increases social cohesion in men; it also increases expression of muscles via the HPP axis. Dopamine which is high during the build-up of masturbation inhibits the HPP axis though, so how can masturbation be causing an increase of prolactin? Well, the hypothalamus can be very intelligent at what it does. It understands context. Not only that, but the massive acute hit of dopamine you are getting causes something called a hormetic effect. Hormesis is kind of like a biological blowback effect, the hypothalamus is massively inhibited on its HPP axis and then to compensate, it releases even more prolactin than it normally would in all that time as a huge burst after orgasm. Not only that, it appears to have "aftershocks" throughout the next few days and releases prolactin even more. But it gets worse. At least with a single mate in a monogamous sexual relationship your dopamine wouldn't be massively elevated, but with access to unlimited high speed pornography your dopamine will spike to never before seen levels due to the Coolidge effect (https://en.wikipedia.org/wiki/Coolidge_effect). What does this mean? For days after masturbation you will have low testosterone. But there's even more. The hypothalamus is a neurological structure. It learns and adapts. What does chronic masturbation and dopamine spiking do to the HPP axis? It makes it less and less sensitive to regular dopamine levels. Throughout the day its perfectly normal and healthy to have a moderate level of dopamine, and especially so for men. If HPP is no longer inhibited by this normal level of dopamine, then prolactin will be chronically elevated. Finally we get to the crux. Chronically elevated prolactin means a chronically inhibited HPG axis. A chronically inhibited HPG axis means chronically low levels of homeostatic testosterone. This is why the men of today have lower testosterone than the average 80 year old just 50 years ago. This is why we have trannies developing feminine traits due to increased prolactin.

Now there's even more danger to all of this. We have huge amounts of xenoestrogens from overcompensation of plant based foods and hygiene products (you really should only be consuming meat). Estrogen stimulates the HPP axis even more, and we have blown our dopamine circuits to defend against them with acute chronic spiking. But the brain can heal and adapt. Stop looking at porn. Stop masturbating. Stop consuming xenoestrogens. Stay monogamous, and only have sex for the purpose of procreation.

Extra Credit: Dangers of SSRIs and Weed SSRIs increase the re-uptake of serotonin in the brain. Serotonin has an antagonist relationship with dopamine, which means if dopamine is high serotonin is low and vice-versa. SSRIs will chronically lower dopamine, not only taking away your enjoyment of novelty, but also once again activating the HPP axis.
Weed is made of cannibinoids. The body produces its own endocannibinoids which have receptors all throughout the nervous system. The hypothalamus is filled with CB1 receptors which have 2-AG (an natural endocannibinoid) as an agonist. 2-AG is released upon orgasm and is used in the adaptation process mentioned earlier to train the hypothalamus to be less responsive to dopamine. What else is an agonist of the CB1 receptor? THC. In fact THC is far more potent than 2-AG could ever be, meaning that every time you smoke weed, you adapt your hypothalamus to be even less responsive to dopamine than if you were masturbating to porn the entire time you were high. THC is bad news if you value testosterone.

Testosterone molecule is totally inactive in the bloodstream. If's only a messenger which in most cells activates synthesis of certain proteins (hormones, enzymes muscle proteins etc,) The message is carried on only if the testosterone hormone binds to its receptor (androgen receptor, located in the nucleus)
For those interested in medicine: the binding of ligand (now lipid soluble steroid hormone) to ifs receptor (now androgen receptor) is much more random than you might think, It's not like ligand and receptor couple everytime they happen to be nearby. The possibility for coupling can be calculated and is called the receptors affinity for ligand

Now I want you to understand that the effect that testosterone has depends from the amount and activity of androgen receptors as well as from the amount of testosterone in bloodstream, So how do we increase the quantity of androgen receptors? -By abstinence, it seems. You all know the theory about our dopamine receptors and what PMO does to them. There is evidence that suggests that the changes in hormones and neurotransmitters caused by orgasm or ejaculation decreases the amount and activity of androgen receptors, Here's my theory from biochemical and medical standpoint

Days 1-5 testosterone levels steadily increase,

Days 6 7 testosterone levels spike radically. Because of abstinence and higher testosterone levels (positive feedback regulation of androgen receptors) quantify and activity of androgen receptors increases.

Days 8 10 testosterone levels crash back to normal, because plasma free testosterone is bound to increased amount of androgen receptors, This is where it gets truly interesting! Next chapter is a bit filled with medical terminology so bare with me...

Here's what should happen next, if my thinking and medicine textbooks are correct: because testosterone is lowered to the "baseline", negative feedback-loop kicks in Plasma testosterone levels are regulated by HPA-axis and many negative feedback-loops. Now that testosterone levels are lowered, hypothalamus (endocrine gland and part of autonomous nervous system) produces more gonadotrophin releasing hormone that stimulates the pituitary gland to produce more luteinizing hormone (LH) which is the major regulator of testosterone synthesis in the Leydig cells of testicles. LH greatly accelerates the ratelimiting reaction of the reaction-chain that synthetizes testosterone by speeding up the transport of cholesterol derivate to right cell compartment. The cholesterol derivate is used to make pro hormone pregnenolone. That's the first major reaction of testosterone biosynthesis.

In plain language this means that if abstinence continues testosterone levels will rise again well over the baseline and the same cycle begins all over again So your testosterone levels and most importantly your androgen receptors will increase more and more by every cycle. That would explain the flatlines and highs that you experience when on longer "streaks", bottom line being that all the time the impact that testosterone has on you will magnify.
Some benefits like better skin can be result from zinc that you save by not ejaculating frequently. It's a fact that the zinc concentration of seminal fluid is relatively highest of all human tissue. It's a fact too that human body does recycle sperm cells and seminal fluid at least to some extent.

@goat2x
“Only have sex for the purpose of procreation” yea you’re a Virgin.
 
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damn this thread is good
 
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@hopecel @wishsiwassalludon @autistic_tendencies @thereallegend
 
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Yeah on no fap you’re horny 24/7.
Not everyone can just deal with that but depends how much you want success
Not for the faint of heart
 
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