current hgh dosing guidelines are likely too low

chudpiller

chudpiller

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TLDR: HGH dosing of 20ius + is probably worth it, especially if you are not planning on being in it for years.

Hello, wanted to share some research I have done on hgh dosing compared to what is produced naturally.
If you are a teen in late puberty, you on average produce about 1.8mg of gh endogenously per day (source). This translates to a bit over 5ius. Since pinning gh reduces natural production (source), pinning gh under 6ius is probably cope, and maybe even a net negative for certain people.

Also, the dose-response relationship appears to be quite preferable up to and exceeding .2ius/kg/day (source). This translates to 14ius for a 150lb person. Therefore, if clinical data shows that you can take such a high dose and not only be fine but have significantly more growth than people taking .1iu/kg/day, why would you not take 20ius or more?

Obviously 20iu/day is gonna be quite expensive, but imo is def worth it especially if you have been taking some cope ahh 4ius. Also, if you combine with teraparatide and tren you will get insane bone growth.

Thanks for reading my first thread, and lmk your thoughts.
 
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This makes me chuckle a little bit because every day I see 20+ posts about "Will CJC 1295 no DAC w IPA make me 6'2" "Will MK677 ascend me?

No mf it won't, HGH won't even do that unless you're taking a shit ton.
 
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Great first post

This makes me chuckle a little bit because every day I see 20+ posts about "Will CJC 1295 no DAC w IPA make me 6'2" "Will MK677 ascend me?

No mf it won't HGH won't even do that unless you're taking a shit ton.
Yea the mods need to pin a thread about how all that shit is cope peddled by people with affiliate links.
 
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learn about pulsatile secretion, this is not how it works

your IGF-1 levels will increase significantly with anywhere from 4ius+

ignore this thread
 
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learn about pulsatile secretion, this is not how it works

your IGF-1 levels will increase significantly with anywhere from 4ius+

ignore this thread
Can you explain why this makes exogenous administration better? Because if anything, not having the pulsation secretions would down regulate the gh signaling pathway.
 
TLDR: HGH dosing of 20ius + is probably worth it, especially if you are not planning on being in it for years.

Hello, wanted to share some research I have done on hgh dosing compared to what is produced naturally.
If you are a teen in late puberty, you on average produce about 1.8mg of gh endogenously per day (source). This translates to a bit over 5ius. Since pinning gh reduces natural production (source), pinning gh under 6ius is probably cope, and maybe even a net negative for certain people.

Also, the dose-response relationship appears to be quite preferable up to and exceeding .2ius/kg/day (source). This translates to 14ius for a 150lb person. Therefore, if clinical data shows that you can take such a high dose and not only be fine but have significantly more growth than people taking .1iu/kg/day, why would you not take 20ius or more?

Obviously 20iu/day is gonna be quite expensive, but imo is def worth it especially if you have been taking some cope ahh 4ius. Also, if you combine with teraparatide and tren you will get insane bone growth.

Thanks for reading my first thread, and lmk your thoughts.
Yeah but ur body doesnt sustain that level the whole day unlike exogenously. I’d just do 9-12iu daily it places u within abnormal igf levels without raping insulin and needing tirzepatide and stuff
 
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TLDR: HGH dosing of 20ius + is probably worth it, especially if you are not planning on being in it for years.

Hello, wanted to share some research I have done on hgh dosing compared to what is produced naturally.
If you are a teen in late puberty, you on average produce about 1.8mg of gh endogenously per day (source). This translates to a bit over 5ius. Since pinning gh reduces natural production (source), pinning gh under 6ius is probably cope, and maybe even a net negative for certain people.

Also, the dose-response relationship appears to be quite preferable up to and exceeding .2ius/kg/day (source). This translates to 14ius for a 150lb person. Therefore, if clinical data shows that you can take such a high dose and not only be fine but have significantly more growth than people taking .1iu/kg/day, why would you not take 20ius or more?

Obviously 20iu/day is gonna be quite expensive, but imo is def worth it especially if you have been taking some cope ahh 4ius. Also, if you combine with teraparatide and tren you will get insane bone growth.

Thanks for reading my first thread, and lmk your thoughts.
.
 
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Can you explain why this makes exogenous administration better? Because if anything, not having the pulsation secretions would down regulate the gh signaling pathway.

natural GH secretion is done in a pulsatile manner, these high levels of GH are for very short time periods throughout the day

exogenous hGH administration allows for these levels to be sustained for long periods of time
 
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Ahh i see, thanks bro. Is this due to the absorption into the bloodstream from subq taking more time as opposed to just getting released straight in?
natural GH secretion is done in a pulsatile manner, these high levels of GH are for very short time periods throughout the day

exogenous hGH administration allows for these levels to be sustained for long periods of tim
 
yes i love acromegaly
I mean according to the study on mega dosing the chinese kids for a year the incidence rate of sides were similar, but granted the study is small.
 
Difference is natural secretion is pulsatile, whereas exogenous hgh is constant receptor activation. 20IU’s is absurd, just look at the FDA approved doses and you’ll notice results can be achieved with much lower doses.
 
Difference is natural secretion is pulsatile, whereas exogenous hgh is constant receptor activation. 20IU’s is absurd, just look at the FDA approved doses and you’ll notice results can be achieved with much lower doses.
Thanks for the clarification. The FDA approved dosages are meant to be used by young children for multiple years though, so it may be different for oldcells on short cycles. Although I acknowledge the enhancement in igf1 from exogenous reguardless.
 
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