Debloating via eplerenone

[Deleted member 150029]

EPLERENONE:

What causes bloating?

Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.

What is aldosterone and its effects?

Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.

What is eplerenone?

Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).

Dosage and timing

Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below

Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.

Side notes (IMPORTANT !!!):

Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.

Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.

Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.

Where to buy?

Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use

TL;DR

Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl

 

[HighInhibHell]

ty, will read later

 

[vi24v_]

mirin

 

[Grievous]

Good thread

 

[sherry12]

Do you recommend, starting lower ex 12.5mgs and working up or just start at 50mgs? Mine arrives soon

 

[Deleted member 150029]

Do you recommend, starting lower ex 12.5mgs and working up or just start at 50mgs? Mine arrives soon

started on 25mg saw no difference hopped to 50mg its only to test whether your body can take it thats all

 

[Mercurius]

ever must be accounted for.

EPLERENONE:

What causes bloating?

Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.

What is aldosterone and its effects?

Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.

What is eplerenone?

Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).

Dosage and timing

Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below

View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.

Side notes (IMPORTANT !!!):

Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.

Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.

Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.

Where to buy?

Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use

TL;DR

Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl

how much water should you drink daily while on ep?

 

[Deleted member 150029]

how much water should you drink daily while on ep?

2.5 litres and above otherwise you get eyebags or opposite effects of what is intended

 

[Mercurius]

2.5 litres and above otherwise you get eyebags or opposite effects of what is intended

and is there anything you can take to prevent hyperkalemia ?

 

[Deleted member 150029]

and is there anything you can take to prevent hyperkalemia ?

not much aside from bloodwork and dosage past 50mg does risk it every dose does have a chance but overall dont go crazy with low sodium cutting it fully first signs are lethargy

 

[Uuatapoiemm]

Do you have to get blood work if you go past 50mg?

 

[Deleted member 150029]

Do you have to get blood work if you go past 50mg?

personally it is recommended but i dont if you do notice tingling weird heart changes those are the first times to stop and assess also bloodwork does clearly show as aldosterone will be high

 

[Uuatapoiemm]

personally it is recommended but i dont if you do notice tingling weird heart changes those are the first times to stop and assess also bloodwork does clearly show as aldosterone will be high

If you notice do you completely stop for a period or lower the dose?

 

[Deleted member 150029]

If you notice do you completely stop for a period or lower the dose?

id genuinely stop it fully but i have not reached a period of that my sample is a bit bias as i have only been on it 4 months never past 100mg also dont stack other diuretics or it increases this risk

 

[Uuatapoiemm]

id genuinely stop it fully but i have not reached a period of that my sample is a bit bias as i have only been on it 4 months never past 100mg also dont stack other diuretics or it increases this risk

Alr thanks so much botb thread btw

 

[Deleted member 150029]

Alr thanks so much botb thread btw

ty ty there are some spelling errors and i can phrase things better might redo it another time

 

[volgaTz]

again bookmarked

 

[Deleted member 150029]

again bookmarked

Ayyy much love lmk if you got questions asw

 

[volgaTz]

Ayyy much love lmk if you got questions asw

I will, thank you brah

 

[wannabemogger]

EPLERENONE:

What causes bloating?

Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.

What is aldosterone and its effects?

Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.

What is eplerenone?

Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).

Dosage and timing

Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below

View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.

Side notes (IMPORTANT !!!):

Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.

Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.

Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.

Where to buy?

Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use

TL;DR

Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl

theres better diuretics you can use to eliminate non hormonal caused water retention (which eplerenone focuses on doing)
good thread tho

 

[Deleted member 150029]

theres better diuretics you can use to eliminate non hormonal caused water retention (which eplerenone focuses on doing)
good thread tho

yeah i was trying to compare but eplerenone is least selective and best long term was thinking about loop as well but dont understand them enough what do you use for diuretics?

 

[wannabemogger]

yeah i was trying to compare but eplerenone is least selective and best long term was thinking about loop as well but dont understand them enough what do you use for diuretics?

eplerenone since im on hormones but also chlorthalidone which i feel can be used much more than loops and also dht steroids dry you out if you wanna try that

if you do use chlorthalidone, people say to use amiloride or potassium supplements to counter the potassium loss but hasnt been a problem for me personally

 

[Deleted member 150029]

eplerenone since im on hormones but also chlorthalidone which i feel can be used much more than loops and also dht steroids dry you out if you wanna try that

if you do use chlorthalidone, people say to use amiloride or potassium supplements to counter the potassium loss but hasnt been a problem for me personally

to be fair i will research this also try sodium free salt for the potassium loss thing it was an old method but worked for me in loop diuretics ty i will check both of them now

 

[Noun]

@hereforever

 

[SideDeltGod]

50mg eple 12,5mg hctz

 

[Deleted member 150029]

50mg eple 12,5mg hctz

Just ordered furosemide hctz chlorthalidone I will check which stack works best but in theory hctz is too weak due to half life chlorthaildone is superior

 

[gamma13]

EPLERENONE:

What causes bloating?

Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.

What is aldosterone and its effects?

Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.

What is eplerenone?

Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).

Dosage and timing

Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below

View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.

Side notes (IMPORTANT !!!):

Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.

Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.

Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.

Where to buy?

Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use

TL;DR

Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl

Dude, I'm feeling tingling in my fingertips, extreme fatigue, I'm sleeping more than 12 hours when the day before I took 50mg of eplerenone, and I have lower back pain. I'm going to end up in the hospital at this rate.

 

[Deleted member 150029]

Dude, I'm feeling tingling in my fingertips, extreme fatigue, I'm sleeping more than 12 hours when the day before I took 50mg of eplerenone, and I have lower back pain. I'm going to end up in the hospital at this rate.

If you’re on eplerneone getting that it’s either hyper or hypo kalemia potassium shit gotta be between 3 and 6 otherwise you just die gang

 

[gamma13]

If you’re on eplerneone getting that it’s either hyper or hypo kalemia potassium shit gotta be between 3 and 6 otherwise you just die gang

Ascend or die

 

[AlphaLooksmaxxer666]

ok thanks

 

[i_blamegamertag]

Ts is too expensive

 

[Deleted member 150029]

Ts is too expensive

ace inhibitors are cheaper however less selective affect entire raas system this is superior you could go for spironolactone instead but affects hormones hctz or chlorthalidone are as well worth a try

 

[i_blamegamertag]

ace inhibitors are cheaper however less selective affect entire raas system this is superior you could go for spironolactone instead but affects hormones hctz or chlorthalidone are as well worth a try

Yea i stole some hctz from my grandma the other day

 

[Deleted member 150029]

Yea i stole some hctz from my grandma the order day

damn lol its kinda useless though requires everyday otherwise it goes away fast good tho needed to mog theses banana copers

 

[i_blamegamertag]

Yea i have barely seen any effects from it sadly

 

[Deleted member 150029]

Yea i have barely seen any effets from it sadly

check sodium balances it causes everything to flush so it might mean potassium too low can counter via eplerenone or ace inhibitors here theres amazing studies combining them as well

 

[i_blamegamertag]

check sodium balances it causes everything to flush so it might mean potassium too low can counter via eplerenone or ace inhibitors here theres amazing studies combining them as well

I eat a fuckton of potassium and very little amount of sodium

 

[i_blamegamertag]

But i got lasix anyways

 

[Deleted member 150029]

I eat a fuckton of potassium and very little amount of sodium

opposite then sodium is too low it flushes everything its not selective at all

 

[i_blamegamertag]

opposite then sodium is too low it flushes everything its not selective at all

Idk bra

 

[Deleted member 150029]

Idk bra

try balance out with eplerenone and see how it works im about to test eplerenone 25mg with 25mg chlorthalidone

 

[i_blamegamertag]

opposite then sodium is too low it flushes everything its not selective at all

Im waiting for my uc machine to arrive and terramog my entire country

 

[i_blamegamertag]

try balance out with eplerenone and see how it works im about to test eplerenone 25mg with 25mg chlorthalidone

I will buy some eple once i start roiding

 

[Deleted member 150029]

Im waiting for my uc machine to arrive and terramog my entire country

YESSIR

I will buy some eple once i start roiding

to be fair i was researching here if youre doing hgh in theory it would only be mild effects due to cortisol and vassopressin also rising not only from hgh but from diuretics as well

 

[Deleted member 351683]

EPLERENONE:

What causes bloating?

Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.

What is aldosterone and its effects?

Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.

What is eplerenone?

Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).

Dosage and timing

Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below

View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.

Side notes (IMPORTANT !!!):

Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.

Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.

Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.

Where to buy?

Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use

TL;DR

Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl

dnr will read later

 

[introvertedextrover]

good guide but it should be used at 25mg for 1-2 weeks to test tolerence then upped to 50mg,
100mg shouldnt ever be taken this is a large dose which is unnesccary as furo should be used in place for quick debloating this is more of a background diuretic
IT takes about 4-6 weeks to see full results aswell

 

[Deleted member 150029]

good guide but it should be used at 25mg for 1-2 weeks to test tolerence then upped to 50mg,
100mg shouldnt ever be taken this is a large dose which is unnesccary as furo should be used in place for quick debloating this is more of a background diuretic
IT takes about 4-6 weeks to see full results aswell

just no need for any of these its already been included and 100mg has been used clinically furo has no similarities to eplerenone causes strong rebound this does not its just for not caring about everyday debloating

 

[themsstrbaiter]

EPLERENONE:

What causes bloating?

Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.

What is aldosterone and its effects?

Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.

What is eplerenone?

Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).

Dosage and timing

Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below

View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.

Side notes (IMPORTANT !!!):

Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.

Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.

Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.

Where to buy?

Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use

TL;DR

Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl

How to prevent hyperkalemia or electrolyte diasregulation?

 

[Deleted member 150029]

How to prevent hyperkalemia or electrolyte diasregulation?

just dont go crazy with potassium you get me
i did read up about a study within taurine actually further amplifying the benefits and potentially getting osmolyte effects however modest

 

[neko]

just dont go crazy with potassium you get me
i did read up about a study within taurine actually further amplifying the benefits and potentially getting osmolyte effects however modest

how much potassium would be to much while taking it?