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Deleted member 150029
Bloatcel
- Joined
- May 8, 2025
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- 946
- OP
- #101
yes however you will still bloat slightly from creatine sadly its quite inevitableIs it fine to pair it with cjc + dac and creatine?
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yes however you will still bloat slightly from creatine sadly its quite inevitableIs it fine to pair it with cjc + dac and creatine?
Yeah and so does cjcyes however you will still bloat slightly from creatine sadly its quite inevitable
yeah i mean hgh to igf1 then holds some extracellular but youd mostly get intra which is good but creatine is a mix of both sadly im not entirely familiar with cjc but the eplerenone might counter the hgh activation of aldosterone depending on dosage just experiment with itYeah and so does cjc![]()
Do you run 50mg 7 days a weekEPLERENONE:
What causes bloating?
Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.
What is aldosterone and its effects?
Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.
What is eplerenone?
Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).
Dosage and timing
Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below
View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.
Side notes (IMPORTANT !!!):
Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.
Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.
Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.
Where to buy?
Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use
TL;DR
Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl
at one point your vasopressin will rise i go for 2-3 months break for 2-4 weeks and its fine and yes daily go for exactly when you wake upDo you run 50mg 7 days a week
Is there a need to hop off for a certain time to let your body rest or can you js run it as long as desired
If you don’t drink enough it doesn’t really work fully if I’m honest you just get crazy eye bags maybe depends on person igHi me again, so is it neccesary to drink 2L-3L of water daily? Because I will never hit that goal honestly and im taking creatine aswell for strength in the gym but can this still keep me strong for lifts but debloat me and make me look sharp? In the sense of best of both worlds
It kinda takes a while to work you won’t really notice anythingIf I take some at 8pm will I be good
In the morning to gym?
alright im like 105lbs I thinkstart at 25mg also it matters not age but weight for most things if it ever starts giving heart palpitations, irregular heart rhythm, very low energy then either stop or lower dosage
Just go for 50mg lowkalright im like 105lbs I think
If I take it, do I need to reduce my potassium intake?EPLERENONE:
What causes bloating?
Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.
What is aldosterone and its effects?
Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.
What is eplerenone?
Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).
Dosage and timing
Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below
View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.
Side notes (IMPORTANT !!!):
Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.
Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.
Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.
Where to buy?
Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use
TL;DR
Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl
No just keep it stableIf I take it, do I need to reduce my potassium intake?
Love itEPLERENONE:
What causes bloating?
Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.
What is aldosterone and its effects?
Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.
What is eplerenone?
Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).
Dosage and timing
Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below
View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.
Side notes (IMPORTANT !!!):
Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.
Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.
Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.
Where to buy?
Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use
TL;DR
Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl
No just keep it stable
Is it dangerous to take 50 mg at 16 years old, 60 kg, 1.80 m tall?EPLERENONE:
What causes bloating?
Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.
What is aldosterone and its effects?
Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.
What is eplerenone?
Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).
Dosage and timing
Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below
View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.
Side notes (IMPORTANT !!!):
Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.
Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.
Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.
Where to buy?
Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use
TL;DR
Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl
Yes, you may die.Is it dangerous to take 50 mg at 16 years old, 60 kg, 1.80 m tall?
You’ll be fine you’re more prone to water at that weight to height ratio anywaysIs it dangerous to take 50 mg at 16 years old, 60 kg, 1.80 m tall?
Chlorthalidone not hctz as it’s longer half life and more effective it’s best to combine if you want cheaper combine chlorthalidone with an arb or worst case ace inhibitor but eplerenone is the cleanestYes, you may die.
Also OP hctz or eplerenone?
Im too much of a brokey for eplerenone and I need to stay debloated 24/7.
Then move on read it and don’t comment on this one retardshitty post we have a guide in botb about ts
i readed the botb thread ngaThen move on read it and don’t comment on this one retard
Illiterate retard don’t comment then bro move on about your dayi readed the botb thread nga
nope loldiuretics and eplerenone will give you erectile dysfunction, your face will look sharper but your dick wont get erect
a true paradox
Why would it take 1-2 weeks to start noticing it happens right awayClinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.
do yk where i can get some cuz wwb dont sellEPLERENONE:
What causes bloating?
Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.
What is aldosterone and its effects?
Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.
What is eplerenone?
Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).
Dosage and timing
Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below
View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.
Side notes (IMPORTANT !!!):
Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.
Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.
Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.
Where to buy?
Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use
TL;DR
Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl
Yes I’ve also been doing both however I’ve targeted dual raas via azilsartan as well genuinely works wonders broIve been using 50mg eple and 25mg hctz daily with no issues also confirmed by blood test. Its actually better to use them both because they balance each other out and you get better debloat obviously. Not a molecule of water in my face
Because it takes a while for fluid shifts as it’s not a loop diuretic it’s gradual and slow it blocks receptors which then lowers water doesn’t flush water directlyWhy would it take 1-2 weeks to start noticing it happens right away
Indiamartdo yk where i can get some cuz wwb dont sell
I’ve been on it for about 8 months now i don’t post my face but it workshave you tried it any before and afters?
8 months of taking diureticsI’ve been on it for about 8 months now i don’t post my face but it works
Half life is 6 hours it works right away and you see debloating same day and achieves peak receptor blockage same dayBecause it takes a while for fluid shifts as it’s not a loop diuretic it’s gradual and slow it blocks receptors which then lowers water doesn’t flush water directly
Existing channels to remove water have longer half life’s although eplerenone blocks faster it takes a while to actually see results it’s indirect diuretic anyways also receptor blocking is second day not same dayHalf life is 6 hours it works right away and you see debloating same day and achieves peak receptor blockage same day
Is still anecdotal/proven or gpt slopExisting channels to remove water have longer half life’s although eplerenone blocks faster it takes a while to actually see results it’s indirect diuretic anyways also receptor blocking is second day not same day
Google search on why diuretics aren’t instantIs still anecdotal/proven or gpt slop
Are you aware that main use of diuretics isn’t debloating you but rather lowering ur bp and improving ur heart conditions which is why google says they aren’t instantGoogle search on why diuretics aren’t instant
how does this compare to furosemideEPLERENONE:
What causes bloating?
Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.
What is aldosterone and its effects?
Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.
What is eplerenone?
Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).
Dosage and timing
Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below
View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.
Side notes (IMPORTANT !!!):
Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.
Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.
Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.
Where to buy?
Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use
TL;DR
Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl
when ur on it do you do anything diffrent, ex: vitamins, foods to watch out for, and other stuff like that or do you just live normally. might seem like a retard question but idk.EPLERENONE:
What causes bloating?
Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.
What is aldosterone and its effects?
Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.
What is eplerenone?
Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).
Dosage and timing
Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below
View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.
Side notes (IMPORTANT !!!):
Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.
Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.
Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.
Where to buy?
Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use
TL;DR
Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl
Boyo are you taking Lisinopril to stay alive or are you raw doggingBut i got lasix anyway
Yeah im 16 and I dont want anything that might even have the possibility of disrupting my hormones, can you please slide ur source for eplerenone? I know its on india mart but I have never bought anything from there before and I just want to cop it off a reputable source ykwimEPLERENONE:
What causes bloating?
Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.
What is aldosterone and its effects?
Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.
What is eplerenone?
Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).
Dosage and timing
Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below
View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.
Side notes (IMPORTANT !!!):
Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.
Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.
Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.
Where to buy?
Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use
TL;DR
Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl
Is this okay to take with hgh so it reduces bloating?EPLERENONE:
What causes bloating?
Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.
What is aldosterone and its effects?
Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.
What is eplerenone?
Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).
Dosage and timing
Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below
View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.
Side notes (IMPORTANT !!!):
Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.
Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.
Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.
Where to buy?
Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use
TL;DR
Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl
do you take 50mg everyday for 2 weeks to see results?EPLERENONE:
What causes bloating?
Bloating or water retention is caused by the balance of sodium potassium and magnesium. These are all regulated by aldosterone and vasopressin, For this guide we will focus on aldosterone.
What is aldosterone and its effects?
Aldosterone is a naturally recurring hormone that signals your body to retain sodium in kidneys and dump potassium into urine which is the exact opposite of what we want. Effects of aldosterone being presently high are persistent water retention, minimal urination, high blood pressure.
What is eplerenone?
Eplerenone is a selective mineralocorticoid receptor antagonist (a form of potassium sparring diuretic) it works by reducing the affect aldosterone has in the kidneys. This causes your body to hold less water by flushing out sodium. Effects are cumulative and persistent while on eplerenone (you will be debloated 24/7 basically no more morning puffiness).
Dosage and timing
Recommended time to take eplerenone is early in the morning just after waking as that is when aldosterone is at its peak. However some studies do show that there is no difference in timing. see below
View attachment 4678036
Clinical doses are most effective at 100mg which is close to fully blocking out receptors this is for the strongest possible receptor blockage. Personally 50mg is the bare minimum to see effects and it would take about 1-2 weeks to start noticing.
Side notes (IMPORTANT !!!):
Eplerenone can cause hyperkalemia which is when potassium levels are elevated in blood due to reduced excretion. Effects of hyperkalemia include; fatigue/numbness, nausea, palpitations, irregular heart rhythm. This will most likely happen on prolonged doses above 100mg very rarely happen on 50mg however must be accounted for.
Eplerenone can also be used to treat acne as it shows signs of mild anti-androgen activity effects are modest more of a bonus inferior to spironolactone.
Lab monitoring can be important but to be fair only useful on doses past 100mg and its a waste of effort.
Where to buy?
Personally, I had purchased via indiamart. Eplerenone is more expensive than other diuretics such as spironolactone however it is much more selective and does not disrupt any hormones which is significant in development. note: aside from renin angiotensen and aldosterone (increases aldosterone but lowers its usage strange) no meaningful effect on development safe to use
TL;DR
Eplerenone = debloat (please read the top though)
if it doesnt work youre just fat ngl