Debunking SlayerJonas thread "The truth about steroids and peptides affecting bones/height"

[nwed]

DISCLAIMER!!!: No hate/beef towards @SlayerJonas i think he is a cool guy and makes high quality posts, the point of his thread is true, roiding for your face is idiotic but saying that roids dont affect your face is misinformation

His claim: The skull is done growing before the realization hits

This is in fact true, and once the bone tissue matures bones can no longer grow longer, we are completely ignoring how bones can grow thicker due to Periostal apposition, wich is directly driven by the Androgen Receptor (AR) and we got a lot of evidence that proves that it can continue throughout adulthood

So with this in mind, we know that even in adulthood, the periosteum continues to provide a source of osteoprogenitor cells, allowing for new osteblast in the outer surface of the bone to form


Some AAS like Nandrolone can drive bone growth through different ways like Sclerostin downregularion wich results in increased Wnt signaling and increased COL1A1 expression, nandrolone also decreases Osteoclasts activity.

So saying “AAS wont change your bone structure cause your bones are done growing by 5” is misinformation

ANYWAYS I LUV YALL AND I HOPE YALL LIKE THE THREAD SINCE I THREW THIS SHIT IN 2 FUCKING MOLECULES OF A SECOND

@flowiza @moliuny @Escanor1 @buccalfatremoval idk who else to ping tbh

 

[Amex.]

bump

 

[Navity]

 

[fraudster#1]

Here comes the so called "looksmaxxing coach"

 

[nwed]

Here comes the so called "looksmaxxing coach"
View attachment 5427183

I have a friend that did 44iu of gh a day and had a 159 FAH, now he is 178 still growing

 

[Yoshiteeq]

I have a friend that did 44iu of gh a day and had a 159 FAH, now he is 178 still growing

doing 44 iu a day meta

 

[Navity]

Here comes the so called "looksmaxxing coach"
View attachment 5427183

Yo bro should I hop on 28 IU HGH everyday, I'm 4'11 and my weight is 40kg

 

[Navity]

I have a friend that did 44iu of gh a day and had a 159 FAH, now he is 178 still growing

Mirrin

 

[fraudster#1]

DISCLAIMER!!!: No hate/beef towards @SlayerJonas i think he is a cool guy and makes high quality posts, the point of his thread is true, roiding for your face is idiotic but saying that roids dont affect your face is misinformation

His claim: The skull is done growing before the realization hits

This is in fact true, and once the bone tissue matures bones can no longer grow longer, we are completely ignoring how bones can grow thicker due to Periostal apposition, wich is directly driven by the Androgen Receptor (AR) and we got a lot of evidence that proves that it can continue throughout adulthood
View attachment 5426946
So with this in mind, we know that even in adulthood, the periosteum continues to provide a source of osteoprogenitor cells, allowing for new osteblast in the outer surface of the bone to form


Some AAS like Nandrolone can drive bone growth through different ways like Sclerostin downregularion wich results in increased Wnt signaling and increased COL1A1 expression, nandrolone also decreases Osteoclasts activity.

So saying “AAS wont change your bone structure cause your bones are done growing by 5” is misinformation

ANYWAYS I LUV YALL AND I HOPE YALL LIKE THE THREAD SINCE I THREW THIS SHIT IN 2 FUCKING MOLECULES OF A SECOND

@flowiza @moliuny @Escanor1 @buccalfatremoval idk who else to ping tbh

nice thread btw but i think you could add more things of things

(It has been shown that when DHT binds to receptors on osteoblasts, the body begins to produce even more androgen receptors)

(increase in igf-1 expression by DHT)

(Osteoblasts in the jaw respond exceptionally well to dht)

DHT and sclerostin expression decreased

and by end mandibular growth driven by nandrolone:

 

[nwed]

nice thread btw but i think you could add more things of things
View attachment 5427193(It has been shown that when DHT binds to receptors on osteoblasts, the body begins to produce even more androgen receptors)
View attachment 5427194(increase in igf-1 expression by DHT)
View attachment 5427195(Osteoblasts in the jaw respond exceptionally well to dht)

DHT and sclerostin expression decreased
View attachment 5427217
View attachment 5427218

and by end mandibular growth driven by nandrolone:
View attachment 5427232

Yess i could but i wrotten this on my phone, its 6am and i threw that in 2 micromolecules of a second

 

[fraudster#1]

Yess i could but i wrotten this on my phone, its 6am and i threw that in 2 micromolecules of a second

tbh i got surprised that almost no one responded his thread before, it's simply horrible

by hisclaim above your chin is supposed to finish growth at age 1 ROFL

 

[jeremyy]

DISCLAIMER!!!: No hate/beef towards @SlayerJonas i think he is a cool guy and makes high quality posts, the point of his thread is true, roiding for your face is idiotic but saying that roids dont affect your face is misinformation

His claim: The skull is done growing before the realization hits

This is in fact true, and once the bone tissue matures bones can no longer grow longer, we are completely ignoring how bones can grow thicker due to Periostal apposition, wich is directly driven by the Androgen Receptor (AR) and we got a lot of evidence that proves that it can continue throughout adulthood
View attachment 5426946
So with this in mind, we know that even in adulthood, the periosteum continues to provide a source of osteoprogenitor cells, allowing for new osteblast in the outer surface of the bone to form


Some AAS like Nandrolone can drive bone growth through different ways like Sclerostin downregularion wich results in increased Wnt signaling and increased COL1A1 expression, nandrolone also decreases Osteoclasts activity.

So saying “AAS wont change your bone structure cause your bones are done growing by 5” is misinformation

ANYWAYS I LUV YALL AND I HOPE YALL LIKE THE THREAD SINCE I THREW THIS SHIT IN 2 FUCKING MOLECULES OF A SECOND

@flowiza @moliuny @Escanor1 @buccalfatremoval idk who else to ping tbh

@SlayerJonas yo.

 

[nwed]

tbh i got surprised that almost no one responded his thread before, it's simply horrible
View attachment 5427242
by hisclaim above your chin is supposed to finish growth at age 1 ROFL

No hate but also jonas thread on diuretics was not that good, i could mention 20 threads that are botb worthy but did not end up in botb