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I was PMing a user of this forum and they mentioned that they were going to be taking delta-sleep-inducing-peptide, aka DSIP. Delta sleep-inducing peptide was first discovered in 1974 by the Swiss Schoenenberger-Monnier group who isolated it from the cerebral venous blood of rabbits in an induced state of sleep. It was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits. Modern-day studies have concluded that this peptide can dramatically improve the sleep quality of those suffering from disorders such as chronic insomnia. So why would us 'looksmaxxers' use this peptide?
well for starters, sleep is a crucial aspect of looking good, feeling good and is detrimental for maintaining a good hormonal profile. In puberty, getting the correct amount of sleep is extremely important, the majority of our growth hormone, luteinizing hormone, and follicle-stimulating hormone are released in high amounts during sleep. LH then signals the Leydig cells in the testicles to produce testosterone creating a cascade of male androgens, growth hormone being converted to IGF-1 and inducing growth and repair in the cells of our body, causing hyperplasia within the tissue.
DSIP basically amplifies this effect by 5-10fold. Delta-sleep-inducing-peptide seems to increase LH by the release of GnRH, this means, more LH, more testosterone,
not only does it dramatically increase the release of LH but it also increases the release of somatropin (GH) and inhibits the release of somatostatin (the hormone that lowers blood serum levels of somatropin). Another contributor to the increase in testosterone is by inhibiting the release of corticotropin, thus decreasing blood serum cortisol and simultaneously increasing testosterone. Great, so by taking 250-300mcg of DSIP we are essentially doubling our release of both LH and GH. Base-line levels of LH in teenagers is already high, meaning you could possibly get your testosterone up into the 1000ng/dl range using this peptide with no negative feedback loops and damage to the HPTA.
Taking this peptide alone is fine, you could reap the benefits, but I'd say it'd be more worth your money if you combined it with either growth hormone or peptides. Combining it with peptides would work well as it has a positive effect on the inhibition of somatostatin, meaning more GH will be secreted via the peptides, you could definitely add exemestane into the mix as it has a very positive effect on the release of LH, you could 100% get your natural testosterone levels to breach 1000ng/dl with this stack, your nuts would become bowling balls with this amount of LH, Jesus christ.
If you're part of the small populace that aren't 'natural' than this peptide can work just as great post-cycle, a couple users on anabolic steroid forums suggest that it speeded up their recovery and increased their LH and testosterone dramatically.
this user on EROIDS, claims that after a couple weeks on his PCT protocol he decided to add DSIP, at 43 years old his testosterone was at 635ng/dl, LH 11, FSH 7, for an old guy who'd just ran compounds like tren you'd think he would have fucked up his HPTA pretty badly, so DSIP seems to be a good addition to a PCT stack.
well for starters, sleep is a crucial aspect of looking good, feeling good and is detrimental for maintaining a good hormonal profile. In puberty, getting the correct amount of sleep is extremely important, the majority of our growth hormone, luteinizing hormone, and follicle-stimulating hormone are released in high amounts during sleep. LH then signals the Leydig cells in the testicles to produce testosterone creating a cascade of male androgens, growth hormone being converted to IGF-1 and inducing growth and repair in the cells of our body, causing hyperplasia within the tissue.
DSIP basically amplifies this effect by 5-10fold. Delta-sleep-inducing-peptide seems to increase LH by the release of GnRH, this means, more LH, more testosterone,
Long term ovariectomized (OVX) Sprague-Dawley rats were injected intraventricularly (3rd ventricle) with 5 micrograms (2 microliters) of DSIP. This caused a significant elevation (p = 0.01) of LH levels within 30 min. The values remained elevated for 2 hr; however, FSH levels remained unchanged. The minimal effective dose of DSIP to evoke this effect was 1 microgram. If plasma PH was lowered by pretreatment of the animals with estradiol, the 5 micrograms dose evoked an even greater effect to elevate LH significantly at 30 and 60 min following its intraventricular injection. To determine the site of action of DSIP, dispersed, overnight cultured pituitary cells from OVX rats were incubated with varying concentrations (10(-7) to 10(-12) M) of DSIP in an in vitro system. There was no response to DSIP from the cells in the above system. To evaluate its possible action on the hypothalamus, median eminence (ME) fragments from male rats were incubated in vitro with DSIP in varying concentrations from 10(-7) to 10(-10) M. There was a significant (p less than 0.001) increase in LHRH released from the ME at a concentration of DSIP of 10(-7) M. A sleep-related increase in LH release is seen during puberty in man. It is possible that DSIP released within the hypothalamus may play a physiological role in sleep-related LH release.
not only does it dramatically increase the release of LH but it also increases the release of somatropin (GH) and inhibits the release of somatostatin (the hormone that lowers blood serum levels of somatropin). Another contributor to the increase in testosterone is by inhibiting the release of corticotropin, thus decreasing blood serum cortisol and simultaneously increasing testosterone. Great, so by taking 250-300mcg of DSIP we are essentially doubling our release of both LH and GH. Base-line levels of LH in teenagers is already high, meaning you could possibly get your testosterone up into the 1000ng/dl range using this peptide with no negative feedback loops and damage to the HPTA.
Taking this peptide alone is fine, you could reap the benefits, but I'd say it'd be more worth your money if you combined it with either growth hormone or peptides. Combining it with peptides would work well as it has a positive effect on the inhibition of somatostatin, meaning more GH will be secreted via the peptides, you could definitely add exemestane into the mix as it has a very positive effect on the release of LH, you could 100% get your natural testosterone levels to breach 1000ng/dl with this stack, your nuts would become bowling balls with this amount of LH, Jesus christ.
If you're part of the small populace that aren't 'natural' than this peptide can work just as great post-cycle, a couple users on anabolic steroid forums suggest that it speeded up their recovery and increased their LH and testosterone dramatically.
Forum: DSIP Delta sleep inducing peptide is a PCT game changer ~humpnpump, 2015
What is DSIP? Wiki explains it pretty well. https://en.m.wikipedia.org/wiki/Delta_sleep-inducing_peptide We've all seen it on the peptide companies menu, but like wtf is this stuff for, there's hardly any info on what it does or how to use it. I got some just to see what it did and to maybe see...
www.eroids.com