ndos
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What is DHEA?
View attachment 1691569852675.webp
Dehydroepiandrosterone (DHEA) is one of the most abundant circulating steroids found in humans. 75–90% of DHEA is synthesized in the adrenal gland (the zona reticularis to be specific) with the remainder being produced by the testes, skin and brain. DHEA is made from cholesterol and its production is stimulated by ACTH and cAMP, both of which can promote the production of cortisol as well.
DHEA provides ≥30% of total androgens in men, but less than 5% of the total circulating testosterone (T) levels are from the conversion of DHEA.
DHEA is a really important protective hormone and is touted as the “fountain of youth”, “the anti-ageing hormone”, to name a few, and should be kept at the high range of normal.
DHEA is reduced in various diseases, such as lupus, arthritis, IBD, Addison’s disease, Crohn’s disease, ulcerative colitis, asthma, allergic rhinitis, urticaria, chronic obstructive pulmonary disease.
DHEA is involved in the skin.
Improves collagen turnover, which helps to reduce wrinkles. Increases skin thickness, suppleness, hydration, sebum production in dry skin and increases skin brightness and reduces the papery look (R).
1) Ashwagandha (R) – Taking 300mg of the KSM-66 extract of Ashwagandha twice daily increased DHEA-S by 18% after 8 weeks.
2) MR-10 – MR-10 is an extract of rooibos and Korean dandelion. 400mg MR-10 taken daily for 4 weeks increased DHEA by 32% (R). MR-10 protects the Leydig cells from age-related stress via the ERK and Akt pathways and enhances endogenous male sex hormone synthesis in vivo.
3) Vitamin D (R) – Vitamin D promotes almost all enzymes involved in steroidogenesis and high vitamin D levels will help to keep DHEA high.
4) Japanese cedar wood essential oil (R) – Inhalation of this essential oil has been shown to have an anti-stress effect that increases DHEA-S.
5) Forskolin, coffee & caffeine – These compounds stimulate cAMP which increases the production of DHEA.
6) Liquorice (R) – The glycyrrhetinic acid in liquorice root increases DHEA by inhibiting its conjugation and detoxification.
7) Vitamin A (R) – Vitamin A increases many enzymes involved in steroidogenesis and the synthesis of DHEA.
8) Tribulus Terrestris (TT) (R) – TT effectively increases DHEA and DHT levels. It’s also effective at increasing dopamine and lowering prolactin and estrogen.
9) Proper sleep (R) – Proper sleep is essential to restore all good and anabolic hormones.
10) Meditation & Tai Chi (R, R) – Reducing stress via meditation or meditative martial arts increases DHEA-S.
View attachment 1691569852675.webp
Dehydroepiandrosterone (DHEA) is one of the most abundant circulating steroids found in humans. 75–90% of DHEA is synthesized in the adrenal gland (the zona reticularis to be specific) with the remainder being produced by the testes, skin and brain. DHEA is made from cholesterol and its production is stimulated by ACTH and cAMP, both of which can promote the production of cortisol as well.
DHEA provides ≥30% of total androgens in men, but less than 5% of the total circulating testosterone (T) levels are from the conversion of DHEA.
DHEA is a really important protective hormone and is touted as the “fountain of youth”, “the anti-ageing hormone”, to name a few, and should be kept at the high range of normal.
DHEA is reduced in various diseases, such as lupus, arthritis, IBD, Addison’s disease, Crohn’s disease, ulcerative colitis, asthma, allergic rhinitis, urticaria, chronic obstructive pulmonary disease.
DHEA is involved in the skin.
Improves collagen turnover, which helps to reduce wrinkles. Increases skin thickness, suppleness, hydration, sebum production in dry skin and increases skin brightness and reduces the papery look (R).
Ways to Increase DHEA levels
1) Ashwagandha (R) – Taking 300mg of the KSM-66 extract of Ashwagandha twice daily increased DHEA-S by 18% after 8 weeks.
2) MR-10 – MR-10 is an extract of rooibos and Korean dandelion. 400mg MR-10 taken daily for 4 weeks increased DHEA by 32% (R). MR-10 protects the Leydig cells from age-related stress via the ERK and Akt pathways and enhances endogenous male sex hormone synthesis in vivo.
3) Vitamin D (R) – Vitamin D promotes almost all enzymes involved in steroidogenesis and high vitamin D levels will help to keep DHEA high.
4) Japanese cedar wood essential oil (R) – Inhalation of this essential oil has been shown to have an anti-stress effect that increases DHEA-S.
5) Forskolin, coffee & caffeine – These compounds stimulate cAMP which increases the production of DHEA.
6) Liquorice (R) – The glycyrrhetinic acid in liquorice root increases DHEA by inhibiting its conjugation and detoxification.
7) Vitamin A (R) – Vitamin A increases many enzymes involved in steroidogenesis and the synthesis of DHEA.
8) Tribulus Terrestris (TT) (R) – TT effectively increases DHEA and DHT levels. It’s also effective at increasing dopamine and lowering prolactin and estrogen.
9) Proper sleep (R) – Proper sleep is essential to restore all good and anabolic hormones.
10) Meditation & Tai Chi (R, R) – Reducing stress via meditation or meditative martial arts increases DHEA-S.
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