DHT = Fucking useless hormone

[Hexmask]

Link thread, I’m always learning.

Go to my profile, I gotta get back to work xD

 

[halloweed]

Go to my profile, I gotta get back to work xD

I’ve checked your profile and couldn’t see it, just link it man.

 

[sb23]

I have 5-AR deficiency. AMA.

How many inches flaccid? Are you being serious? Have you considered enlargement surgery?

 

[St.TikTokcel]

How many inches flaccid? Are you being serious? Have you considered enlargement surgery?

Idk but my body looks like this with a flatter stomach.

 

[Hexmask]

Fine negroid. Only because u contribute to the forum

I’ve checked your profile and couldn’t see it, just link it man.

How To Avoid Nocebo From Finasteride/Dutasteride

This will be a quick and simple guide to avoid nocebo effect when taking finasteride or dutasteride. What is nocebo? Per the dictionary: "when a patient's negative expectations about a medical treatment cause them to experience undesirable symptoms or illnesses, even though the treatment has no...

looksmax.org

 

[halloweed]

Fine negroid. Only because u contribute to the forum

How To Avoid Nocebo From Finasteride/Dutasteride

This will be a quick and simple guide to avoid nocebo effect when taking finasteride or dutasteride. What is nocebo? Per the dictionary: "when a patient's negative expectations about a medical treatment cause them to experience undesirable symptoms or illnesses, even though the treatment has no...

looksmax.org

Thanks negro

 

[Saint Casanova]

DHT plays a vital role during gestation and somewhat during puberty. After then it’s useless but keep uploading images of little dicks if that’s your thing

 

[halloweed]

DHT plays a vital role during gestation and somewhat during puberty. After then it’s useless but keep uploading images of little dicks if that’s your thing

I’m still going through puberty negro

 

[noodlelover]

I’m pretty impressed how many fear mongering people got to some of you forum users. Let’s run some things through.

Wrong. In fact on the dutasteride insert depression and anxiety isn’t even listed as a side effect of the medication.

Not listing a symptom doesn't mean people don't experience it.

The only reason fin has it listed was because of the PFS foundation. They did follow up studies and declared they could not draw any conclusions on it causing mental issues, especially considering how many prescriptions were administered.

What study? Who funded it? How many participants? How long? How did they measure variables?


Here's a bunch of human studies that look at finasteride users that quit because of negative mental health effects, some of those long lasting.

Emotional Consequences of Finasteride: Fool’s Gold - PMC

Androgenetic alopecia, the gradual, progressive loss of hair frequently results in psychological despair, in part related to changes in self-image. Current androgenetic alopecia treatments are limited to hair transplantation and medications that ...

pmc.ncbi.nlm.nih.gov

Depression circumstantially related to the administration of finasteride for androgenetic alopecia - PubMed

In this paper we report 19 patients (14 males, 5 females; mean age 28.16 years +/- 7.68 SD) out of a series of 23 (17 males, 5 females) who developed a mood disturbance (moderate to severe depression) during treatment with finasteride, 1 mg/day orally, for androgenetic alopecia (Hamilton...

pubmed.ncbi.nlm.nih.gov

Persistent sexual, emotional, and cognitive impairment post-finasteride: a survey of men reporting symptoms - PubMed

Finasteride is a synthetic 5-α reductase inhibitor, which prevents the conversion of testosterone to dihydrotestosterone and has been used for more than 20 years in the treatment of male pattern hair loss. Randomized, controlled trials have associated finasteride with both reversible and...

pubmed.ncbi.nlm.nih.gov

Depressive symptoms and suicidal thoughts among former users of finasteride with persistent sexual side effects - PubMed

Clinicians and potential users of finasteride should be aware of the potential risk of depressive symptoms and suicidal thoughts. The preliminary findings of this study warrant further research with controlled studies.

pubmed.ncbi.nlm.nih.gov

Adverse side effects of 5α-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients - PubMed

We suggest discussion with patients on the potential sexual side effects of 5α-RIs before commencing therapy. Alternative therapies may be considered in the discussion, especially when treating androgenetic alopecia.

pubmed.ncbi.nlm.nih.gov

Secondly, if you look up the molecular weight of the molecule, it’s barely at the same amount of molecular weight needed to even be able to pass through the blood brain barrier.

It's not about the molecule. It's the fact that it inhibits DHT. That's going to have all kinds of downstream negative effects.

The mice studies are not comparable to humans. Not only because we are not mice but in the studies they used ten fold the normal dose something unachievable by humans to even take.

Yet humans report having the similar symptoms.

One study they dropped mice in water one on fin and the others not and recorded how long it would take for them to give up.

Willingness to fight for survival is a good measure of how much you want to live.

Insufficient evidence. Additionally, most “studies” done are mechanistic in nature which means it’s only looking at a fraction of what’s going on.

We have to make conclusions with the evidence we have. No study on anything in 100% conclusive.

They don’t continue doing studies because there have been plenty done on this topic to conclude there is zero reason to worry and most people just nocebo themselves.

Where are these studies you speak of?

I genuinely feel bad for people like you and for others who come across your comments of ignorance towards DHT blockers. It’s the best drug I’ve taken and millions of other men have taken. Good luck to you and your hairline. I hope minoxidil and a derma stamp can work JFL.

I tried finasteride, and it was the worst experience I've ever had. Felt depressed drugged up, out of it, unable to focus. It was not a placebo, I wasn't expecting to feel like that. Horrible horrible experience.

I'm lucky that the effects went away after I stopped. Not every one is as lucky as me.

@halloweed @Saint Casanova

 

[Hexmask]

Not listing a symptom doesn't mean people don't experience it.


What study? Who funded it? How many participants? How long? How did they measure variables?


Here's a bunch of human studies that look at finasteride users that quit because of negative mental health effects, some of those long lasting.

Emotional Consequences of Finasteride: Fool’s Gold - PMC

Androgenetic alopecia, the gradual, progressive loss of hair frequently results in psychological despair, in part related to changes in self-image. Current androgenetic alopecia treatments are limited to hair transplantation and medications that ...

pmc.ncbi.nlm.nih.gov

Depression circumstantially related to the administration of finasteride for androgenetic alopecia - PubMed

In this paper we report 19 patients (14 males, 5 females; mean age 28.16 years +/- 7.68 SD) out of a series of 23 (17 males, 5 females) who developed a mood disturbance (moderate to severe depression) during treatment with finasteride, 1 mg/day orally, for androgenetic alopecia (Hamilton...

pubmed.ncbi.nlm.nih.gov

Persistent sexual, emotional, and cognitive impairment post-finasteride: a survey of men reporting symptoms - PubMed

Finasteride is a synthetic 5-α reductase inhibitor, which prevents the conversion of testosterone to dihydrotestosterone and has been used for more than 20 years in the treatment of male pattern hair loss. Randomized, controlled trials have associated finasteride with both reversible and...

pubmed.ncbi.nlm.nih.gov

Depressive symptoms and suicidal thoughts among former users of finasteride with persistent sexual side effects - PubMed

Clinicians and potential users of finasteride should be aware of the potential risk of depressive symptoms and suicidal thoughts. The preliminary findings of this study warrant further research with controlled studies.

pubmed.ncbi.nlm.nih.gov

Adverse side effects of 5α-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients - PubMed

We suggest discussion with patients on the potential sexual side effects of 5α-RIs before commencing therapy. Alternative therapies may be considered in the discussion, especially when treating androgenetic alopecia.

pubmed.ncbi.nlm.nih.gov

It's not about the molecule. It's the fact that it inhibits DHT. That's going to have all kinds of downstream negative effects.


Yet humans report having the similar symptoms.

Willingness to fight for survival is a good measure of how much you want to live.

We have to make conclusions with the evidence we have. No study on anything in 100% conclusive.

Where are these studies you speak of?


I tried finasteride, and it was the worst experience I've ever had. Felt depressed drugged up, out of it, unable to focus. It was not a placebo, I wasn't expecting to feel like that. Horrible horrible experience.

I'm lucky that the effects went away after I stopped. Not every one is as lucky as me.

@halloweed @Saint Casanova

I honestly don’t have the patience to reply to every single one of these. I personally think though that you probably nocebo’d yourself. And yes the effects do away there is no solid evidence PFS is even real. Any symptoms are reversible(that happen to 1 percent of people out of millions)

 

[Hexmask]

Not listing a symptom doesn't mean people don't experience it.


What study? Who funded it? How many participants? How long? How did they measure variables?


Here's a bunch of human studies that look at finasteride users that quit because of negative mental health effects, some of those long lasting.

Emotional Consequences of Finasteride: Fool’s Gold - PMC

Androgenetic alopecia, the gradual, progressive loss of hair frequently results in psychological despair, in part related to changes in self-image. Current androgenetic alopecia treatments are limited to hair transplantation and medications that ...

pmc.ncbi.nlm.nih.gov

Depression circumstantially related to the administration of finasteride for androgenetic alopecia - PubMed

In this paper we report 19 patients (14 males, 5 females; mean age 28.16 years +/- 7.68 SD) out of a series of 23 (17 males, 5 females) who developed a mood disturbance (moderate to severe depression) during treatment with finasteride, 1 mg/day orally, for androgenetic alopecia (Hamilton...

pubmed.ncbi.nlm.nih.gov

Persistent sexual, emotional, and cognitive impairment post-finasteride: a survey of men reporting symptoms - PubMed

Finasteride is a synthetic 5-α reductase inhibitor, which prevents the conversion of testosterone to dihydrotestosterone and has been used for more than 20 years in the treatment of male pattern hair loss. Randomized, controlled trials have associated finasteride with both reversible and...

pubmed.ncbi.nlm.nih.gov

Depressive symptoms and suicidal thoughts among former users of finasteride with persistent sexual side effects - PubMed

Clinicians and potential users of finasteride should be aware of the potential risk of depressive symptoms and suicidal thoughts. The preliminary findings of this study warrant further research with controlled studies.

pubmed.ncbi.nlm.nih.gov

Adverse side effects of 5α-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients - PubMed

We suggest discussion with patients on the potential sexual side effects of 5α-RIs before commencing therapy. Alternative therapies may be considered in the discussion, especially when treating androgenetic alopecia.

pubmed.ncbi.nlm.nih.gov

It's not about the molecule. It's the fact that it inhibits DHT. That's going to have all kinds of downstream negative effects.


Yet humans report having the similar symptoms.

Willingness to fight for survival is a good measure of how much you want to live.

We have to make conclusions with the evidence we have. No study on anything in 100% conclusive.

Where are these studies you speak of?


I tried finasteride, and it was the worst experience I've ever had. Felt depressed drugged up, out of it, unable to focus. It was not a placebo, I wasn't expecting to feel like that. Horrible horrible experience.

I'm lucky that the effects went away after I stopped. Not every one is as lucky as me.

@halloweed @Saint Casanova

By the way, did you even go through any of those studies? All of them either aren’t actual testing or they have no conclusive evidence they can draw to. Honestly what a joke you even argued this.

 

[noodlelover]

I honestly don’t have the patience to reply to every single one of these.

I'm not surprised.

So you're admitting that you made up studies you mentioned in your first post, or they weren't strong enough for you to link.

I personally think though that you probably nocebo’d yourself.

I definitely didn't.

(that happen to 1 percent of people out of millions)

Made up statistic.

By the way, did you even go through any of those studies? All of them either aren’t actual testing or they have no conclusive evidence they can draw to.

I'm aware of what the studies I linked say.

What you're not considering is how to weigh evidence.

What is the default assumption, before you start weighing evidence to tip the scales to one side or another?

Why would you assume without evidence that ANYTHING naturally produced in the human body doesn't have purpose, and inhibiting it isn't going to have all kinds of negative down stream effects?

That's a bold assumption. And then on top of it, we see in mouse studies that it does have other effects, that help the mice fight for survival in a life or death situation.

The collection of self reported anecdotal human reports, of all the people stopping medication because they are having these side effects, is a low weight of evidence, but when you consider it in context and weigh it appropriately you see that most likely, yes inhibiting DHT is bad for you.

For clarity of discussion.

So, we start with the default assumption that blocking this random hormone that's not yet understood by science is probably bad. And then we look for evidence to change our default assumption one way or another.

Then we see the mice studies, tipping the scales further to, yes inhibiting DHT is even more likely to be bad.

Then the human reports on top, tipping the scales even further to the side of, there's risk here. Not definitive proof but the probabilities are weighted to one side.

Your thinking is, the default assumption is taking this random medication is most definitely safe, and I need a mountain of proof beyond a shadow of a doubt before I stop taking it. That's a crazy assumption, about any medication.

If it's working for you then go ahead and keep using it. But don't dismiss the experiences out of hand of so many other people so quickly.

Honestly what a joke you even argued this.

I wish you could discuss this logically, and not so emotionally, not give up and resort to ad hominins, provide the studies you claim exist to prove your claim about inhibiting DHT not having side effects on mental well being.

Maybe it's because you're inhibiting DHT that you can't think clearly.

 

[Mike141]

You if you had testosterone without DHT :
Right guy doesn’t have a 5-AR deficiency (enzyme which converts testosterone to DHT)
View attachment 3321625
https://www.sciencedirect.com/science/article/abs/pii/0002934377903138
Others look normal eh?
View attachment 3321633

Another cuck with a 5-AR deficiency.

View attachment 3321627
His dick:
View attachment 3321626
Microscopic penis

https://pubmed.ncbi.nlm.nih.gov/36268297/

Another 5-AR deficiency untermensch faggot

View attachment 3321624
Trash hormone
https://pubmed.ncbi.nlm.nih.gov/37180321/


View attachment 3321648
View attachment 3321650View attachment 3321651
Every subhuman soul here will look like these moggers after nuking that horrendous and dogshit hormone. Fuck DHT.

@20/04/2008 @craven @Jonas2k7 @sb23 @wastedspermcel

i’m dht filled and mog to the depths of gandys hell

 

[glaruz]

calling reduction of DHT production "weak ass" doesn't negate the effects on the body.

You still have 30%+ of your DHT and even more in tissues and DHT is useless in adults anyways.

 

[Alucard69]

This isn't just due to DHT deficiency, bad example

 

[balkancel000]

Dht haters will be raped by me in the depths of hell

 

[noodlelover]

You still have 30%+ of your DHT and even more in tissues

You're reducing it enough to make a change in the body. With hormones you can't think about quantities being proportional in size as being proportional in meaning. Hormones typically have non-linear effects.

and DHT is useless in adults anyways.

You don't know that.

 

[CalulArgintiu59]

Very important in puberty, but if prone to balding, def screw up DHT