Do Ai's get rid of local e2?

[Skeletal]

I honestly want to run something like 2 gramms of testoserone and crushing e2 with letrozole but people say ai won't get rid of local aromatisation I don't really believe this here is some proof

https://link.springer.com/article/10.1186/s13058-017-0910-x?utm

https://pubmed.ncbi.nlm.nih.gov/12915670/

https://pubmed.ncbi.nlm.nih.gov/15813607/

Ai's have been prooven to slow down bone age meaning it acts on the bone aswell.
Idk im a low iq user could someone enlighten me?

 

[Skeletal]

bump

 

[fataholic]

how old are you

 

[Skeletal]

how old are you

15

 

[Skeletal]

b

 

[fataholic]

15

2g is a lot have you done test previously and is there anything else you're running

 

[Skeletal]

2g is a lot have you done test previously and is there anything else you're running

yeah im running tren and low dose test.
don't worry about me I just want to if ai will be enough to not fuse my gp

 

[Skeletal]

b

 

[odb]

I honestly want to run something like 2 gramms of testoserone and crushing e2 with letrozole but people say ai won't get rid of local aromatisation I don't really believe this here is some proof

https://link.springer.com/article/10.1186/s13058-017-0910-x?utm

https://pubmed.ncbi.nlm.nih.gov/12915670/

https://pubmed.ncbi.nlm.nih.gov/15813607/

Ai's have been prooven to slow down bone age meaning it acts on the bone aswell.
Idk im a low iq user could someone enlighten me?

 

[Skeletal]

just answear bro

 

[ascend_forget]

ive had the same concern it seems it localizes in bone unfortounatelely you could use endoxofin the metabolite in nolvadex that works like a aggonist in bone just use a trt base and keep e2 10-15 and use dht derevatives that dont lower e2 like varr mast DHB deca or do a eq cycle with a estrogen base

 

[fataholic]

yeah im running tren and low dose test.
don't worry about me I just want to if ai will be enough to not fuse my gp

yes its enough but be safe and go with a higher dose you can always softmax denser bones but never longer limbs. May I ask what your dosages are right now and what you've seen from it

 

[copeuntilumakeit]

yeah im running tren and low dose test.
don't worry about me I just want to if ai will be enough to not fuse my gp

nigga do NOT use 2g of test if you are not a top bodybuilder what tf are you rthinking?

 

[Skeletal]

nigga do NOT use 2g of test if you are not a top bodybuilder what tf are you rthinking?

1g

 

[copeuntilumakeit]

1g

1g is and the higher end, i would do 500 of test and up the tren and hgh cuz increasing test will just age you

 

[fataholic]

oh good thats a safe dose just dont do 1.1 or you will spontaneously combust

1g

 

[ascend_forget]

yeah im running tren and low dose test.
don't worry about me I just want to if ai will be enough to not fuse my gp

same but careful with tren your brain is developing tren will fuck up a bit im 16 on tren to btw if youre curious run diehexa to protect your brain while you are still developing run forskolin also to activate CAMP to prevent epyphisial closure

 

[Skeletal]

are there high iq user who could actually show me evidence that ai doesn't get rid of local e2 cuz im really curious since test is hella cheap unlike dht deriv
@PharmaPhaggot sry for @ u so much but ur really one of the only i trust

 

[fataholic]

why would you wanna use a dht deriv

are there high iq user who could actually show me evidence that ai doesn't get rid of local e2 cuz im really curious since test is hella cheap unlike dht deriv
@PharmaPhaggot sry for @ u so much but ur really one of the only i trust

 

[fataholic]

are there high iq user who could actually show me evidence that ai doesn't get rid of local e2 cuz im really curious since test is hella cheap unlike dht deriv
@PharmaPhaggot sry for @ u so much but ur really one of the only i trust

Novel treatment of short stature with aromatase inhibitors - PubMed

Estrogens have an essential role in the regulation of bone maturation and importantly in the closure of growth plates in both sexes. This prospective, randomized, placebo-controlled study was undertaken to evaluate whether suppression of estrogen synthesis in pubertal boys delays bone maturation...

pubmed.ncbi.nlm.nih.gov

delayed pubertal boys given test and an aromatase inhibitor had their growth plate openness prolonged

aromatase inhibitors work locally not systemically

Expression of aromatase in the human growth plate - PubMed

Aromatase catalyzes the synthesis of estrogen from its androgen precursors. Estrogen is known to be important in regulating long bone growth and epiphyseal plate closure. To assess whether there may be growth plate-specific production of estrogen, we performed reverse transcriptase polymerase...

pubmed.ncbi.nlm.nih.gov

 

[Skeletal]

aromatase inhibitors work locally not systemically

ai do work systemically aswell

 

[Skeletal]

why would you wanna use a dht deriv

its almost like test but no aromatisation

 

[ascend_forget]

why would you wanna use a dht deriv

cause it dosent aromataise locally in bone

 

[fataholic]

cause it dosent aromataise locally in bone

good point i guess but thats what aromatase inhibitors are for and also wont destroy your hair

 

[Skeletal]

good point i guess but thats what aromatase inhibitors are for and also wont destroy your hair

yeah but seems like you can't block all e2 locally what most ppl claim I want actual evidence

 

[PharmaPhaggot]

are there high iq user who could actually show me evidence that ai doesn't get rid of local e2 cuz im really curious since test is hella cheap unlike dht deriv
@PharmaPhaggot sry for @ u so much but ur really one of the only i trust

There isnt, because ai does do that

And to your last mention, yes keep taking gh, you might not get extra height but theres good chances you do, and extra height for a few hundred $ is a steal

 

[fataholic]

cause it dosent aromataise locally in bone

i understand i just didnt get it cause you could use test with an ai but anavar would work nicely

 

[fataholic]

yeah but seems like you can't block all e2 locally what most ppl claim I want actual evidence

letrozole blocks 99% aromatase and anastrozole blocks 97% if you had no aromatase your whole life you'd grow for a comically long time, into your late 20s possibly even 30 but rare

 

[Skeletal]

There isnt, because ai does do that

And to your last mention, yes keep taking gh, you might not get extra height but theres good chances you do, and extra height for a few hundred $ is a steal

aight thanks man appreiciate you always helping me ill be blasting grams of test

 

[fataholic]

aight thanks man appreiciate you always helping me ill be blasting grams of test

update us or give us a before and after we'll be waiting to hear how it goes

 

[Skeletal]

update us or give us a before and after we'll be waiting to hear how it goes

sure man ill @ u

 

[fataholic]

sure man ill @ u

thank you bhai