does running hgh along wiht mk677 shut down endogenous production?

[gamma2]

title and are there any advantages of running both?

 

[cumbutamoren]

Low iq to run mk with gh. The whole point of mk is cheap/easier to source, literally zero advantage over gh otherwise. Plus, you cant measure the gh increase from mk unless u test igf, while injecting gh increases it by an exact amount

 

[gamma2]

Low iq to run mk with gh. The whole point of mk is cheap/easier to source, literally zero advantage over gh otherwise. Plus, you cant measure the gh increase from mk unless u test igf, while injecting gh increases it by an exact amount

i was wondering because mk is speculated to reduce the effects somatostatin (gh inhibiting hormone) from the gh injections, not necessarily for increasing igf levels.

 

[cumbutamoren]

i was wondering because mk is speculated to reduce the effects somatostatin (gh inhibiting hormone) from the gh injections, not necessarily for increasing igf levels.

Not necessary. Running GH means you are replacing your endogenous gh production, at least while you are running it. Reducing somatostatin will have little effect, since your natural production will be crushed anyway.

Plus, mk does not reduce somatostatin long term, at least not in rats. “Somatostatin (SST) mRNA expression in the hypothalamus was markedly increased in the treatment group”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240568/

Mk may be useful to recover endogenous GH after your cycle, but you will naturally recover within a couple days anyway.

 

[gamma2]

Not necessary. Running GH means you are replacing your endogenous gh production, at least while you are running it. Reducing somatostatin will have little effect, since your natural production will be crushed anyway.

Plus, mk does not reduce somatostatin long term, at least not in rats. “Somatostatin (SST) mRNA expression in the hypothalamus was markedly increased in the treatment group”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240568/

Mk may be useful to recover endogenous GH after your cycle, but you will naturally recover within a couple days anyway.

how many ius a days do u think is enough to gain a net benefit of gh through injection (since you obviously replace endogenous production)? also how do u supplement the other shut endogenous growth hormones since you only supplement one type of gh through injection?

 

[cumbutamoren]

how many ius a days do u think is enough to gain a net benefit of gh through injection (since you obviously replace endogenous production)? also how do u supplement the other shut endogenous growth hormones since you only supplement one type of gh through injection?

To know your endogenous production, you should probably get tested since it may vary by age and other factors. Generally, 0.5 IU is the very minimum to see benefits, and 2iu is a common dose. Bodybuilders may take much higher doses, really depends on your purpose.

As for the other types of GH being shut down, theres not much you can do. the good news is that they all serve very similar functions anyway, so its not as big of a deal as it sounds.

 

[gamma2]

To know your endogenous production, you should probably get tested since it may vary by age and other factors. Generally, 0.5 IU is the very minimum to see benefits, and 2iu is a common dose. Bodybuilders may take much higher doses, really depends on your purpose.

As for the other types of GH being shut down, theres not much you can do. the good news is that they all serve very similar functions anyway, so its not as big of a deal as it sounds.

thanks that seems like a bit of a lifefuel