Doesn't carnivore nuke your IGF-1?!

[mandiblade]

I'm saying this as someone who was a carnivore for 3 weeks...but 2 weeks ago. I didn't quit for this reason, but if I'm to return, I will need this answered

My concern arose after reading this study(its abstract but whatever man).

Effects of fasting on the growth plate: systemic and local mechanisms - PubMed

Inadequate caloric intake inhibits longitudinal bone growth. This study was designed to investigate the mechanisms responsible for this suppression of growth plate function, focusing on the roles of systemic and local insulin-like growth factor 1 (IGF-1). Five week-old male rabbits were fasted...

pubmed.ncbi.nlm.nih.gov

These effects appear to be mediated by systemic endocrine mechanisms; circulating IGF-1 levels are diminished because of hepatic resistance to GH.

Especially if you do OMAD, your hGH levels will be very high. However, it won't able to do much because hGH is useless on its own for longitudinal bone growth. You need IGF-1. The small insulin release you get from fat and protein consumption will not necessarily be enough to reverse this resistance and produce IGF-1.

Short periods of hyperinsulinemia are very beneficial for IGF-1 levels for the following reasons

Insulin is molecularly similar to IGF-1, so an increase of insulin means more IGFBP is bound to insulin instead of IGF-1, giving you even more free IGF-1

The Association Between IGF-I and Insulin Resistance: A general population study in Danish adults - PMC

IGF-I has an almost 50% amino acid sequence homology with insulin and elicits nearly the same hypoglycemic response. Studies showed that low and high IGF-I levels are related to impaired glucose tolerance and to a higher risk of type 2 diabetes. The ...

pmc.ncbi.nlm.nih.gov

insulin stimulates hepatic IGF-I synthesis

The Association Between IGF-I and Insulin Resistance: A general population study in Danish adults - PMC

IGF-I has an almost 50% amino acid sequence homology with insulin and elicits nearly the same hypoglycemic response. Studies showed that low and high IGF-I levels are related to impaired glucose tolerance and to a higher risk of type 2 diabetes. The ...

pmc.ncbi.nlm.nih.gov

increases the fraction of circulating free IGF-I by downregulating hepatic synthesis of IGFBP-1 and, to a lesser extent, hepatic secretion of IGFBP-2

The Proliferating Role of Insulin and Insulin-Like Growth Factors in Cancer - PMC

Epidemiological studies have reported an increased risk of cancer in those with type 2 diabetes (T2DM) and obesity, related in part to hyperinsulinemia, secondary to insulin resistance. Hyperinsulinemia leads to increased insulin-like growth ...

pmc.ncbi.nlm.nih.gov

higher insulin levels in the portal circulation upregulate the growth hormone receptor

The last thing will cause you to secrete even more hGH, which would cause even higher amounts of IGF-1.


Calling all carnivores

@HostSamurai @IAMNOTANINCEL @Never Get Up @superpsycho
@MyDreamIsToBe183CM because you know about longitudinal bone growth

Btw please do not say things like "xyz is a jew" you're just going to make all of us carnivores look dumb

 

[socdom]

Yes

 

[willmogalways]

Yes, there is also associated studies to carnivores having less bone density

 

[mandiblade]

@Kelly Oubre Jr
You also encouraged carnivore on asdvek's randle cyle post

 

[They_are_all_whores]

Yes, there is also associated studies to carnivores having less bone density

where

 

[chadisbeingmade]

The only reason to eat carbs is pre workout to fuel your session, wether you are natural or not.

I have done all diets apart from vegan. Full carnivore is based if you don’t workout at all, and I got the most shredded I ever have on it.

 

[Never Get Up]

I hate this world.

 

[willmogalways]

The only reason to eat carbs is pre workout to fuel your session, wether you are natural or not.

I have done it all, 0 carbs, keto, high carb.

Carbohydrates are a source of energy yes, but you do need glucose to signal mTOR and growth pathways, by just eating carnivore you are willingly choosing not to.

 

[goyimslayer]

I hate this world.

That's okay, had you been vegan you would've been happier.

/s

 

[Sonneillon]

Yes, there is also associated studies to carnivores having less bone density

Im interested show

 

[They_are_all_whores]

Carbohydrates are a source of energy yes, but you do need glucose to signal mTOR and growth pathways, by just eating carnivore you are willingly choosing not to.

show us

 

[socdom]

Carbohydrates are a source of energy yes, but you do need glucose to signal mTOR and growth pathways, by just eating carnivore you are willingly choosing not to.

1kg carb binge

 

[chadisbeingmade]

Carbohydrates are a source of energy yes, but you do need glucose to signal mTOR and growth pathways, by just eating carnivore you are willingly choosing not to.

The science doesn’t mean shit. People now grow up to be subhuman due to their carbohydrate filled diet with a lack of micronutrients. Meat is the most importnt part of the diet and should be the main part.

 

[Never Get Up]

Carbohydrates are a source of energy yes, but you do need glucose to signal mTOR and growth pathways, by just eating carnivore you are willingly choosing not to.

You have a low IQ.

Gluconeogenesis exists for a reason.

 

[Kelly Oubre Jr]

@Kelly Oubre Jr
You also encouraged carnivore on asdvek's randle cyle post

theres probably a compensatory upregulation of igf1 receptors and other pathways, i wouldnt think it makes too much of a difference. and yeah i still think carnivore is one of the best diets for naturals, if youre really concerned about carbs/insulin/igf1 then add fruit post workout, youll stay in ketosis that way and still get an insulin spike when your hgh is high

 

[Never Get Up]

The science doesn’t mean shit. People now grow up to be subhuman due to their carbohydrate filled diet with a lack of micronutrients. Meat is the most importnt part of the diet and should be the main part.

should be the only part.*

 

[mandiblade]

Gluconeogenesis exists for a reason.

Well I guess this isn't the reason

Dietary Protein and the Blood Glucose Concentration - PMC

pmc.ncbi.nlm.nih.gov

Later, in 1924, MacLean (7) fed 50 g of meat protein to two subjects, one with and one without mild diabetes. The theoretical amount of glucose that could be produced was 25 g. However, there was no change in blood glucose

The idea that 50-80% of your dietary protein becomes glucose is a myth.

 

[mandiblade]

The pro-carb guys are glazing too hard and the zerocarb guys are hating too hard

There is no level of health or optimization that carbs give you that you cannot get while keto-adapted on carnivore. Their only purpose I can see is for blood sugar and IGF-1 spikes. I outlined a guide in this reddit comment(that is my account). I'll post it to r/carnivore in a while إنشاء الله.
(read both comments)



I forgot to mention this in my comments, but according to the OP of that reddit thread, bovine colostrum has bioavailable IGF-1 as well. Didn't research that but I'll take his word for it.


Carnivores, critique the "takeaway" section as needed - using logic, not brainless insults.

 

[mandiblade]

if youre really concerned about carbs/insulin/igf1 then add fruit post workout, youll stay in ketosis that way and still get an insulin spike when your hgh is high

I agree this does seem ideal
You would probbaly also want to drink a ton of raw milk for lactoferrin and stuff and pasteurized milk from injected cows for orally bioavailable IGF-1.

 

[willmogalways]

You have a low IQ.

Gluconeogenesis exists for a reason.

Gluconeogenesis doesnt apply to fatty acids in humans.

Do your research before trying to get at me, you are just a lower iq version of Edward A Goeke.

The science doesn’t mean shit. People now grow up to be subhuman due to their carbohydrate filled diet with a lack of micronutrients. Meat is the most importnt part of the diet and should be the main part.

This is just you admitting to pseudoscience.

 

[chadisbeingmade]

This is just you admitting to pseudoscience

With your theory they should he mogger due to sky high igf1 through constant eating of carbs. That’s not the case. Optimal diet is what we evolved off, which is prominently meat.

 

[IAMNOTANINCEL]

Yes

 

[pinterest]

The only reason to eat carbs is pre workout to fuel your session, wether you are natural or not.

I have done all diets apart from vegan. Full carnivore is based if you don’t workout at all, and I got the most shredded I ever have on it.

I’ve seen your pfp on Pinterest