Doesn't carnivore nuke your IGF-1?!

mandiblade

mandiblade

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I'm saying this as someone who was a carnivore for 3 weeks...but 2 weeks ago. I didn't quit for this reason, but if I'm to return, I will need this answered

My concern arose after reading this study(its abstract but whatever man).
These effects appear to be mediated by systemic endocrine mechanisms; circulating IGF-1 levels are diminished because of hepatic resistance to GH.
Especially if you do OMAD, your hGH levels will be very high. However, it won't able to do much because hGH is useless on its own for longitudinal bone growth. You need IGF-1. The small insulin release you get from fat and protein consumption will not necessarily be enough to reverse this resistance and produce IGF-1.

Short periods of hyperinsulinemia are very beneficial for IGF-1 levels for the following reasons

Insulin is molecularly similar to IGF-1, so an increase of insulin means more IGFBP is bound to insulin instead of IGF-1, giving you even more free IGF-1

insulin stimulates hepatic IGF-I synthesis

increases the fraction of circulating free IGF-I by downregulating hepatic synthesis of IGFBP-1 and, to a lesser extent, hepatic secretion of IGFBP-2

higher insulin levels in the portal circulation upregulate the growth hormone receptor
The last thing will cause you to secrete even more hGH, which would cause even higher amounts of IGF-1.


Calling all carnivores

@HostSamurai @IAMNOTANINCEL @Never Get Up @superpsycho
@MyDreamIsToBe183CM because you know about longitudinal bone growth

Btw please do not say things like "xyz is a jew" you're just going to make all of us carnivores look dumb
 
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Yes, there is also associated studies to carnivores having less bone density
 
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@Kelly Oubre Jr
You also encouraged carnivore on asdvek's randle cyle post
 
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The only reason to eat carbs is pre workout to fuel your session, wether you are natural or not.

I have done all diets apart from vegan. Full carnivore is based if you don’t workout at all, and I got the most shredded I ever have on it.
 
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I hate this world.
 
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The only reason to eat carbs is pre workout to fuel your session, wether you are natural or not.

I have done it all, 0 carbs, keto, high carb.
Carbohydrates are a source of energy yes, but you do need glucose to signal mTOR and growth pathways, by just eating carnivore you are willingly choosing not to.
 
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Carbohydrates are a source of energy yes, but you do need glucose to signal mTOR and growth pathways, by just eating carnivore you are willingly choosing not to.
show us
 
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Carbohydrates are a source of energy yes, but you do need glucose to signal mTOR and growth pathways, by just eating carnivore you are willingly choosing not to.
1kg carb binge
 
Carbohydrates are a source of energy yes, but you do need glucose to signal mTOR and growth pathways, by just eating carnivore you are willingly choosing not to.
The science doesn’t mean shit. People now grow up to be subhuman due to their carbohydrate filled diet with a lack of micronutrients. Meat is the most importnt part of the diet and should be the main part.
 
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Carbohydrates are a source of energy yes, but you do need glucose to signal mTOR and growth pathways, by just eating carnivore you are willingly choosing not to.
You have a low IQ.

Gluconeogenesis exists for a reason.
 
@Kelly Oubre Jr
You also encouraged carnivore on asdvek's randle cyle post
theres probably a compensatory upregulation of igf1 receptors and other pathways, i wouldnt think it makes too much of a difference. and yeah i still think carnivore is one of the best diets for naturals, if youre really concerned about carbs/insulin/igf1 then add fruit post workout, youll stay in ketosis that way and still get an insulin spike when your hgh is high
 
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The science doesn’t mean shit. People now grow up to be subhuman due to their carbohydrate filled diet with a lack of micronutrients. Meat is the most importnt part of the diet and should be the main part.
should be the only part.*
 
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Gluconeogenesis exists for a reason.
Well I guess this isn't the reason

Later, in 1924, MacLean (7) fed 50 g of meat protein to two subjects, one with and one without mild diabetes. The theoretical amount of glucose that could be produced was 25 g. However, there was no change in blood glucose

The idea that 50-80% of your dietary protein becomes glucose is a myth.
 
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The pro-carb guys are glazing too hard and the zerocarb guys are hating too hard

There is no level of health or optimization that carbs give you that you cannot get while keto-adapted on carnivore. Their only purpose I can see is for blood sugar and IGF-1 spikes. I outlined a guide in this reddit comment(that is my account). I'll post it to r/carnivore in a while إنشاء الله.
(read both comments)



I forgot to mention this in my comments, but according to the OP of that reddit thread, bovine colostrum has bioavailable IGF-1 as well. Didn't research that but I'll take his word for it.


Carnivores, critique the "takeaway" section as needed - using logic, not brainless insults.
 
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if youre really concerned about carbs/insulin/igf1 then add fruit post workout, youll stay in ketosis that way and still get an insulin spike when your hgh is high
I agree this does seem ideal
You would probbaly also want to drink a ton of raw milk for lactoferrin and stuff and pasteurized milk from injected cows for orally bioavailable IGF-1.
 
You have a low IQ.

Gluconeogenesis exists for a reason.
Gluconeogenesis doesnt apply to fatty acids in humans.

Do your research before trying to get at me, you are just a lower iq version of Edward A Goeke.
The science doesn’t mean shit. People now grow up to be subhuman due to their carbohydrate filled diet with a lack of micronutrients. Meat is the most importnt part of the diet and should be the main part.
This is just you admitting to pseudoscience.
 
This is just you admitting to pseudoscience
With your theory they should he mogger due to sky high igf1 through constant eating of carbs. That’s not the case. Optimal diet is what we evolved off, which is prominently meat.
 
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Yes
 
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The only reason to eat carbs is pre workout to fuel your session, wether you are natural or not.

I have done all diets apart from vegan. Full carnivore is based if you don’t workout at all, and I got the most shredded I ever have on it.
I’ve seen your pfp on Pinterest
 
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I'm saying this as someone who was a carnivore for 3 weeks...but 2 weeks ago. I didn't quit for this reason, but if I'm to return, I will need this answered

My concern arose after reading this study(its abstract but whatever man).

Especially if you do OMAD, your hGH levels will be very high. However, it won't able to do much because hGH is useless on its own for longitudinal bone growth. You need IGF-1. The small insulin release you get from fat and protein consumption will not necessarily be enough to reverse this resistance and produce IGF-1.

Short periods of hyperinsulinemia are very beneficial for IGF-1 levels for the following reasons

Insulin is molecularly similar to IGF-1, so an increase of insulin means more IGFBP is bound to insulin instead of IGF-1, giving you even more free IGF-1






The last thing will cause you to secrete even more hGH, which would cause even higher amounts of IGF-1.


Calling all carnivores

@HostSamurai @IAMNOTANINCEL @Never Get Up @superpsycho
@MyDreamIsToBe183CM because you know about longitudinal bone growth

Btw please do not say things like "xyz is a jew" you're just going to make all of us carnivores look dumb
Yes carnivore is flawed
 
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I'm saying this as someone who was a carnivore for 3 weeks...but 2 weeks ago. I didn't quit for this reason, but if I'm to return, I will need this answered

My concern arose after reading this study(its abstract but whatever man).

Especially if you do OMAD, your hGH levels will be very high. However, it won't able to do much because hGH is useless on its own for longitudinal bone growth. You need IGF-1. The small insulin release you get from fat and protein consumption will not necessarily be enough to reverse this resistance and produce IGF-1.

Short periods of hyperinsulinemia are very beneficial for IGF-1 levels for the following reasons

Insulin is molecularly similar to IGF-1, so an increase of insulin means more IGFBP is bound to insulin instead of IGF-1, giving you even more free IGF-1






The last thing will cause you to secrete even more hGH, which would cause even higher amounts of IGF-1.


Calling all carnivores

@HostSamurai @IAMNOTANINCEL @Never Get Up @superpsycho
@MyDreamIsToBe183CM because you know about longitudinal bone growth

Btw please do not say things like "xyz is a jew" you're just going to make all of us carnivores look dumb
yea
 
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include sugar from milk honey fruits and berries, also, what many dont know, muscle meat is high in glucose
 
The science doesn’t mean shit. People now grow up to be subhuman due to their carbohydrate filled diet with a lack of micronutrients. Meat is the most importnt part of the diet and should be the main part.
real
 
Almost this entire thread is lowiq. Almost everyone here, including me, believed that exogenous carbohydrates are necessary for insulin secretion. This is not true. BCAA consumption causes an insulin spike, which you will need for your body not to go to waste as a carnivore(or a homo sapien in general lol).
This is that compensatory igf1 secretion mechanism that @Kelly Oubre Jr was speaking of.

Like I said earlier, OMAD may be suboptimal, but I am planning to come into contact with a highiqcel carnivore(got his email) to confirm.
Well I guess this isn't the reason



The idea that 50-80% of your dietary protein becomes glucose is a myth.
This is not the same as having an insulin spike. I might read the study later(I only skimmed the abstract earlier), but gluconeogenesis is not 100% supply driven or demand driven, so YMMV if you conduct this experiment yourself. It's not 100% extrapolatable onto anyone else.
I agree this does seem ideal
You would probbaly also want to drink a ton of raw milk for lactoferrin and stuff and pasteurized milk from injected cows for orally bioavailable IGF-1.
Lowiq lol. Fruits aren't necessarily needed for IGF-1, as your hepatic hGH sensitivity does not linearly increase with insulin spikes(like @chadisbeingmade was saying). Basically, insulin will sensitize your liver to hGH, but after you have reached the binary state of sensitivity, insulin will do you no good (it's technically a spectrum ofc, but there is obv a maximum). As rabits need insulin for hGH sensitivity as well, this dependency may be shared by all mammals, so I might look into this for carnivorous mammals as well, if I get bored enough(I have better things to do, looksmaxxing-wise, so prob not).
About raw milk, I still hold the position that raw uninfected milk would be better than normal milk for heightmaxxing, but you can just pin lactoferrin and hGH so the risk isn't really that worth it.
About injected milk, KEK at the idea that I thought that was good lol.



I may further evicerate and elaborate upon the takes in this threas, but someone should ping me in about 2 weeks for that.
@They_are_all_whores @Never Get Up
 
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Almost this entire thread is lowiq. Almost everyone here, including me, believed that exogenous carbohydrates are necessary for insulin secretion. This is not true. BCAA consumption causes an insulin spike, which you will need for your body not to go to waste as a carnivore(or a homo sapien in general lol).
This is that compensatory igf1 secretion mechanism that @Kelly Oubre Jr was speaking of.

Like I said earlier, OMAD may be suboptimal, but I am planning to come into contact with a highiqcel carnivore(got his email) to confirm.

This is not the same as having an insulin spike. I might read the study later(I only skimmed the abstract earlier), but gluconeogenesis is not 100% supply driven or demand driven, so YMMV if you conduct this experiment yourself. It's not 100% extrapolatable onto anyone else.

Lowiq lol. Fruits aren't necessarily needed for IGF-1, as your hepatic hGH sensitivity does not linearly increase with insulin spikes(like @chadisbeingmade was saying). Basically, insulin will sensitize your liver to hGH, but after you have reached the binary state of sensitivity, insulin will do you no good (it's technically a spectrum ofc, but there is obv a maximum). As rabits need insulin for hGH sensitivity as well, this dependency may be shared by all mammals, so I might look into this for carnivorous mammals as well, if I get bored enough(I have better things to do, looksmaxxing-wise, so prob not).
About raw milk, I still hold the position that raw uninfected milk would be better than normal milk for heightmaxxing, but you can just pin lactoferrin and hGH so the risk isn't really that worth it.
About injected milk, KEK at the idea that I thought that was good lol.



I may further evicerate and elaborate upon the takes in this threas, but someone should ping me in about 2 weeks for that.
@They_are_all_whores @Never Get Up
So in general what diet is best for growth and health

Is fiber and carbs a silent killer
 
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So in general what diet is best for growth and health
Growth: Our height decreased after the agricultural revolution, and the US's average height for 19 year olds finally evened out in 2023. Took 13K years for that to happen. Carnivore with sufficient insulin spikes will not take you beyond your genetic potential, but would rather prevent diet-based stunting.
Health: carnivore
Is fiber and carbs a silent killer
Fiber, no way. Doesn't mean you should be eating it though. Carbs aren't going to kill you before 70, but they will contribute to suboptimal health(glycation etc).
 
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Growth: Our height decreased after the agricultural revolution, and the US's average height for 19 year olds finally evened out in 2023. Took 13K years for that to happen. Carnivore with sufficient insulin spikes will not take you beyond your genetic potential, but would rather prevent diet-based stunting.
Health: carnivore

Fiber, no way. Doesn't mean you should be eating it though. Carbs aren't going to kill you before 70, but they will contribute to suboptimal health(glycation etc).
Where can I learn like u did bhai:owo:
 
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