Eating a high fat/keto diet and raising your cholesterol will NOT raise your testosterone. It will only contribute to ASCVD, and likely even lower it.

[Deleted member 23391]

Stop listening to broscience from idiot gymcels. Cholesterol is NOT the rate-limiting factor of steroidogenesis. In men without damage to the testicles, the reason for lower testosterone is SECONDARY (having to do with the hypothalamus or pituitary not sending enough of a signal to the testicles). Not insufficient cholesterol or fat. That is to say that testosterone levels are regulated by brain signaling. The endogenous cholesterol production is more than enough to supply substrate for testosterone synthesis, hence why vegans have similar levels of testosterone to meat eaters despite eating little to no cholesterol.

Vegans have equal or higher testosterone levels:
https://pubmed.ncbi.nlm.nih.gov/32332862/
https://pubmed.ncbi.nlm.nih.gov/33599941/

For testosterone synthesis cholesterol requirements, healthy adult males produce ~14-42 micromoles testosterone per day:
https://www.ncbi.nlm.nih.gov/pubmed/14083165

One molecule of testosterone requires one molecule of cholesterol. Under gonadotropin stimulation, 700 million Leydig cells (however, adults can have up to 1573 million so this is a conservative estimate - pubmed.gov/3779804) synthesize ~13.2 micromoles per day when external sources are not provided:
https://www.ncbi.nlm.nih.gov/pubmed/736271
https://www.ncbi.nlm.nih.gov/pubmed/2226298

Meaning some plasma import is theoretically required. In humans, LDLR is the primary pathway for this, while SRB1 functions as a backup:
https://www.ncbi.nlm.nih.gov/pubmed/20515451

LDLR kinetics saturate at ~25mg/dL plasma LDL-C:
https://www.ncbi.nlm.nih.gov/pubmed/198627

whereas SRB1 kinetics saturate at ~30 mg/dL plasma HDL-C:
https://www.ncbi.nlm.nih.gov/pubmed/10872459

What that means is testosterone production is not substrate-limited unless there is extremely low blood cholesterol levels, achievable only with drugs and/or rare genetic disorders, not dietary cholesterol restriction. The human liver alone (the intestine being the other source of LDL and HDL) is capable of endogenously synthesizing ~2.6 micromoles of cholesterol per kg bodyweight per day, more than enough when considering ~70% circulating LDL-C remains unused and is simply taken up by the liver again for recycling:
https://www.ncbi.nlm.nih.gov/pubmed/8245716

Testosterone production in adult males is 4-12 mg/day, while endogenous cholesterol synthesis in humans is 12-13 mg/kg a day. The receptors responsible for delivering cholesterol to Leydig cells are saturated at 50 mg/dL and 30 mg/dL blood LDL-C and HDL-C, respectively. You have more than enough:
http://science.sciencemag.org/content/232/4746/34
http://science.sciencemag.org/content/271/5248/518

Over and above this is actually bad, for the cells can become overloaded with cholesterol or it can start to oxidize, both of which are toxic and impair production:
http://www.sciencedirect.com/science/article/pii/S002191509900310X
http://www.jbc.org/content/288/16/11509.short

Not to mention carbs are critical to have high testosterone because of SHBG, this is a protein that binds to testosterone and renders it inert. Eating carbohydrate blocks SHBG synthesis in the liver because of the increases in insulin which increases free testosterone. The more insulin you have over the course of the day, the lower the SHBG. Also, ketosis increases cortisol which reduces testosterone biosynthesis.

High SHBG is a common problem among carnivore diet practitioners. Their terrible blood work is a lot of the reason many such as Paul Saladino have started to embrace eating carbs. Also low insulin -> low IGF-1 -> stunted growth (teencels take note) @BrahminBoss

 

[Krakowski]

So how am I supposed to eat then

 

[thereallegend]

Simple (not refined) carbs do increase free testosterone and lower sex binding hormone globulin.

 

[BrahminBoss]

You are an idiot. People who have higher thyroid levels can eat more saturated fat as their rate of steroidogenesis is extremely high (hyperthyroid people produce DHT at 8x an euthyroid man's). Saturated fat also has some anti oxidant functions on its own, which is why artifically reducing cholestrol through statins actually increases mortality.

 

[Deleted member 47099]

High fat diet doesn’t make any sense, u only need little bit of fat for hormones, carbs and protein is way better building muscle and energy

 

[thereallegend]

Not to mention carbs are critical to have high testosterone because of SHBG, this is a protein that binds to testosterone and renders it inert. Eating carbohydrate blocks SHBG synthesis in the liver because of the increases in insulin which increases free testosterone. The more insulin you have over the course of the day, the lower the SHBG. Also, ketosis increases cortisol which reduces testosterone biosynthesis.

High SHBG is a common problem among carnivore diet practitioners. Their terrible blood work is a lot of the reason many such as Paul Saladino have started to embrace eating carbs. Also low insulin -> low IGF-1 -> stunted growth

This is why I'ved added simple carbs back in. Like fruits, vegetable juice, maple syrup, honey, custard

 

[thereallegend]

Keto does raise your cortisol. I became way more alert on keto. Taking carbs makes me feel so relaxed like I'm sedated.

 

[thereallegend]

High fat diet doesn’t make any sense, u only need little bit of fat for hormones, carbs and protein is way better building muscle and energy

Ketosis is a better source of energy than glucose.

 

[BrahminBoss]

High fat diet doesn’t make any sense, u only need little bit of fat for hormones, carbs and protein is way better building muscle and energy

High protein will cause hypothyroidism and aging if its high in methionine and cysteine

 

[bradpittshairline]

i dont have any low T symptoms or traits but can u make a guide on how to keep these levels intact or improve

 

[BrahminBoss]

i dont have any low T symptoms or traits

You hit the vape and look like a Dravidian fuckdoll for punjabi bvlls. Yoy are as low T as they get

 

[bradpittshairline]

You hit the vape and look like a Dravidian fuckdoll for punjabi bvlls. Yoy are as low T as they get

ur literally south indian dravidian why u dick riding punjabi jfl

low T self hating cuck

 

[BrahminBoss]

ur literally south indian dravidian why u dick riding punjabi jfl

low T self hating cuck

If im south indian then you are an abo (which you actually are but I didnt want to be mean)

 

[bradpittshairline]

If im south indian then you are an abo (which you actually are but I didnt want to be mean)

idc if im abo but no way ur not south indian + ur so doomed u gotta squint after getting chantoplasty

 

[DR. NICKGA]

Stop listening to broscience from idiot gymcels. Cholesterol is NOT the rate-limiting factor of steroidogenesis. In men without damage to the testicles, the reason for lower testosterone is SECONDARY (having to do with the hypothalamus or pituitary not sending enough of a signal to the testicles). Not insufficient cholesterol or fat. That is to say that testosterone levels are regulated by brain signaling. The endogenous cholesterol production is more than enough to supply substrate for testosterone synthesis, hence why vegans have similar levels of testosterone to meat eaters despite eating little to no cholesterol.

Vegans have equal or higher testosterone levels:
https://pubmed.ncbi.nlm.nih.gov/32332862/
https://pubmed.ncbi.nlm.nih.gov/33599941/

For testosterone synthesis cholesterol requirements, healthy adult males produce ~14-42 micromoles testosterone per day:
https://www.ncbi.nlm.nih.gov/pubmed/14083165

One molecule of testosterone requires one molecule of cholesterol. Under gonadotropin stimulation, 700 million Leydig cells (however, adults can have up to 1573 million so this is a conservative estimate - pubmed.gov/3779804) synthesize ~13.2 micromoles per day when external sources are not provided:
https://www.ncbi.nlm.nih.gov/pubmed/736271
https://www.ncbi.nlm.nih.gov/pubmed/2226298

Meaning some plasma import is theoretically required. In humans, LDLR is the primary pathway for this, while SRB1 functions as a backup:
https://www.ncbi.nlm.nih.gov/pubmed/20515451

LDLR kinetics saturate at ~25mg/dL plasma LDL-C:
https://www.ncbi.nlm.nih.gov/pubmed/198627

whereas SRB1 kinetics saturate at ~30 mg/dL plasma HDL-C:
https://www.ncbi.nlm.nih.gov/pubmed/10872459

What that means is testosterone production is not substrate-limited unless there is extremely low blood cholesterol levels, achievable only with drugs and/or rare genetic disorders, not dietary cholesterol restriction. The human liver alone (the intestine being the other source of LDL and HDL) is capable of endogenously synthesizing ~2.6 micromoles of cholesterol per kg bodyweight per day, more than enough when considering ~70% circulating LDL-C remains unused and is simply taken up by the liver again for recycling:
https://www.ncbi.nlm.nih.gov/pubmed/8245716

Testosterone production in adult males is 4-12 mg/day, while endogenous cholesterol synthesis in humans is 12-13 mg/kg a day. The receptors responsible for delivering cholesterol to Leydig cells are saturated at 50 mg/dL and 30 mg/dL blood LDL-C and HDL-C, respectively. You have more than enough:
http://science.sciencemag.org/content/232/4746/34
http://science.sciencemag.org/content/271/5248/518

Over and above this is actually bad, for the cells can become overloaded with cholesterol or it can start to oxidize, both of which are toxic and impair production:
http://www.sciencedirect.com/science/article/pii/S002191509900310X
http://www.jbc.org/content/288/16/11509.short

Not to mention carbs are critical to have high testosterone because of SHBG, this is a protein that binds to testosterone and renders it inert. Eating carbohydrate blocks SHBG synthesis in the liver because of the increases in insulin which increases free testosterone. The more insulin you have over the course of the day, the lower the SHBG. Also, ketosis increases cortisol which reduces testosterone biosynthesis.

High SHBG is a common problem among carnivore diet practitioners. Their terrible blood work is a lot of the reason many such as Paul Saladino have started to embrace eating carbs. Also low insulin -> low IGF-1 -> stunted growth (teencels take note) @BrahminBoss

You are an idiot. People who have higher thyroid levels can eat more saturated fat as their rate of steroidogenesis is extremely high (hyperthyroid people produce DHT at 8x an euthyroid man's). Saturated fat also has some anti oxidant functions on its own, which is why artifically reducing cholestrol through statins actually increases mortality.

THE NERD FIGHT IS GONNA HAPPEND

WHICH AUTIST WILL WIN THE DEBATE?

 

[Deleted member 47099]

Ketosis is a better source of energy than glucose.

Your muscles literally made of glucose/glycogen/sugar+water

 

[thereallegend]

Your muscles literally made of glucose/glycogen/sugar+water

Your body creates it's own glucose. It's called gluconeogenesis. Carbs aren't essential to the human diet. It's only the cherry on top.

 

[Deleted member 47099]

Your body creates its own glucose. It's called gluconeogenesis. Carbs aren't essential to the human diet. It's only the cherry on top.

Maybe if you’re sedentary u don’t need it but u need it if u wanna build any muscle or have good cardio

 

[OENKENNETH]

This thread is so retarded.Keto does give higher test but it lowers free t quite a bit.

 

[Deleted member 23391]

This thread is so retarded.Keto does give higher test but it lowers free t quite a bit.

support your claims retard, also free T is ultimately the only T that matters

if it does raise total T it's because your free T is cratered and SHBG is sky high, so BRAIN SIGNALING (NOT more fat and cholesterol) tells you testicles to produce more

fat/cholesterol was never the bottleneck

 

[Deleted member 23391]

Your body creates it's own glucose. It's called gluconeogenesis. Carbs aren't essential to the human diet. It's only the cherry on top.

"they aren't essential to the human diet but your body literally creates it because it would die without it"

 

[thereallegend]

"they aren't essential to the human diet but your body literally creates it because it would die without it"

GLUCOSE IS NECESSARY BUT CARBS ARE NOT