F**k Tretinoin, fucked my hooding, F**K, F**K, F**K!!!

[Soalian]

F**KKKKKKKKKKKKK!!!!!!!!!

Research Note: All-trans retinoic acids induce adipogenic differentiation of chicken embryonic fibroblasts and preadipocytes

Adipocytes store excess energy in the form of lipids, whereas fat accretion contributes to feed efficiency, meat quality, and female reproduction in p…

www.sciencedirect.com

Distinct stages in adipogenesis revealed by retinoid inhibition of differentiation after induction of PPARgamma - PubMed

Retinoic acid (RA) inhibits adipocyte differentiation of 3T3-L1 preadipocytes but is effective only early in adipogenesis. RA prevented induction of the adipogenic factors PPARgamma and C/EBPalpha. Using receptor-specific ligands, we determined that the effects of RA were mediated by liganded RA...

pubmed.ncbi.nlm.nih.gov

Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation

Abstract. Retinoic acid (RA), a bioactive metabolite of vitamin A, is a critical mediator of cell differentiation. RA blocks adipogenesis, but mechanisms r

academic.oup.com

F**k Tretinoin.

 

[Deleted member 12758]

Mmmmmm kinda got the point, it messes your fat distribution or what, thats why I dont even take accutane who the f knows what that shit does

 

[Deleted member 2403]

I'm gonna keep using it idgaf, you fear mongerer, i need better skin

 

[Deleted member 7076]

retin a is literally my favourite looksmax go kys op

i still have full hooding after using 0.05% for several months

 

[Soalian]

Why didn't I read those studies sooner ffs.

Retinoic acid blocks adipogenesis by inhibiting C/EBPbeta-mediated transcription | Molecular and Cellular Biology

Adipocyte differentiation is thought to involve sequential induction of the transcription factors C/EBPbeta, peroxisome proliferator-activated receptor gamma (PPARgamma), and C/EBPalpha. C/EBPalpha expression is both necessary and sufficient for ...

mcb.asm.org

 

[Soalian]

I'm gonna keep using it idgaf, you fear mongerer, i need better skin

How long have you been using it for? Do you use it near the eyelids?

 

[Soalian]

Mmmmmm kinda got the point, it messes your fat distribution or what, thats why I dont even take accutane who the f knows what that shit does

Gotta try it for yourself I guess, responses to Tretinoin are highly individual, from what it seems.

 

[Soalian]

retin a is literally my favourite looksmax go kys op

i still have full hooding after using 0.05% for several months

You lucked out bro.

 

[sKdLeL]

Tldr?

 

[Deleted member 7651]

Only if u apply it on your eyes like the retard you are

 

[HeavenAdmιn]

Retina is unironically one of the most godtier looksmaxxes there are.

 

[Soalian]

Retina is unironically one of the most godtier looksmaxxes there are.

Name a better skincare looksmax. I'll wait.

 

[Deleted member 55559]

How long have you been using it for? Do you use it near the eyelids?

Wtf? Near the eyelids?? Also read the fat pads come back to normal after a week or weeks