fgfr3 inhibitor

[theprogresspath]

has anyone used fgfr3 inhibitor? to long gate the time your epiphyseal plates are active, if did how was your experience?

 

[Lauren de Graaf]

bro came from that one Anton video

 

[exsttttt]

has anyone used fgfr3 inhibitor? to long gate the time your epiphyseal plates are active, if did how was your experience?

im boutta hop on infi, but it aint used to prolong gp activity/delay fusion
it just increases prolif in pz and increases hypertrophy in hz slightly delays fusion but not as much as nuking e2 would

 

[exsttttt]

bro came from that one Anton video

that nigga talkin bout tyra300 it costs like 1k a gram its only benefit is its fgfr3 selective over infigratinib but ud need like 50mg per day to exceed infigs effectiveness at that point ur lookin at 50 bucks a day

 

[infrainfra]

im boutta hop on infi, but it aint used to prolong gp activity/delay fusion
it just increases prolif in pz and increases hypertrophy in hz slightly delays fusion but not as much as nuking e2 would

how would you source infig? it also inhibits fgfr2 which is needed later on for bone.

 

[exsttttt]

how would you source infig? it also inhibits fgfr2 which is needed later on for bone.

quite frankly fgfr2 also is a negative brake somewhat on the craniofacial bones just like fgfr3 is on long bones but to a less extent.

 

[pedro218]

fgfr2 also is a negative brake somewhat on the craniofacial bones

that's is new for me... thanks for spoke

 

[pedro218]

btw, vosoritide doesnt inhib directly FGFR3 and is more expensive than infigratinib

 

[pedro218]

that nigga talkin bout tyra300 it costs like 1k a gram its only benefit is its fgfr3 selective over infigratinib but ud need like 50mg per day to exceed infigs effectiveness at that point ur lookin at 50 bucks a day

what dosage mg/kg do you think that is ideal for infi?

 

[blamelars]

im boutta hop on infi, but it aint used to prolong gp activity/delay fusion
it just increases prolif in pz and increases hypertrophy in hz slightly delays fusion but not as much as nuking e2 would

yo bro dm me

 

[exsttttt]

what dosage mg/kg do you think that is ideal for infi?

0.25mg/kg/day was found effective and safe in dwarf children, u prolly could push it to 0.4mg/kg if you manage phosphate levels since 0.25mg/kg was found to be effective in dwarf kids not normal kids, dwarfs obviously will need a much lower dose to increase velocity since their fgfr3 is so hyperactive that even a 30% inhibition could lead to dramatic results.

 

[exsttttt]

btw, vosoritide doesnt inhib directly FGFR3 and is more expensive than infigratinib

well its the same downstream target of erk/mapk. both the cnp pathway and fgfr3 crosstalk there hence why vosoritide is used in achondroplasia.

 

[pedro218]

0.25mg/kg/day was found effective and safe in dwarf children, u prolly could push it to 0.4mg/kg if you manage phosphate levels since 0.25mg/kg was found to be effective in dwarf kids not normal kids, dwarfs obviously will need a much lower dose to increase velocity since their fgfr3 is so hyperactive that even a 30% inhibition could lead to dramatic results.

i'll buy today

 

[Kklars]

i'll buy today

from where?? dm gng

 

[pedro218]

send your discord to me

from where?? dm gng

 

[Kklars]

send your discord to me

@Kklars

 

[plutolock]

send your discord to me

can u add me too, my discord is plutoverified

 

[pedro218]

can u add me too, my discord is plutoverified

sent

 

[theprogresspath]

you can you message me the source to

 

[arrzsz]

sent

sent

U think I could get it too?

 

[pedro218]

U think I could get it too?

yea

 

[benal22]

yea

tell me bro

 

[pedro218]

tell me bro

everyone that wanna ask me about things, add me on discord, coriolano._.