Finasterdie and brain

Peroxide

Peroxide

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I heard that fin can damage your brain. How the fin exactly works with brain and which areas of brain can fin fuck up?
 
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don't know about brain but the libido can surely take a hit
 
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gymislife said:
don't know about brain but the libido can surely take a hit
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Thats for sure, but i wonder how exactly it affects brain and is there some way to prevent brain sides like brain fogs
 
DHT is anxiolytic, it's the reason why men have less anxiety than foids.
Some men develop anxiety disorders while on fin.
 
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Stare said:
DHT is anxiolytic, it's the reason why men have less anxiety than foids.
Some men develop anxiety disorders while on fin.
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fuck dat
 
I don’t think balding is good for your brain baldcel
 
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Look at Connor murphy he became a nut job.
But tbh I would still take it I would rather be crazy and have hair than be bald.
 
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Peroxide said:
Thats for sure, but i wonder how exactly it affects brain and is there some way to prevent brain sides like brain fogs
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en.wikipedia.org

Finasteride - Wikipedia

en.wikipedia.org en.wikipedia.org
Finasteride may cause persistent adverse sexual, neurological and physical effects in a subset of men.[13][14] This has been called post-finasteride syndrome, characterized by reported sexual and physical symptoms such as loss of libido, erectile dysfunction, ejaculatory disorders, reduction in penis size, penile curvature, reduced sensation, male breast enlargement, muscular atrophy, fatigue and severely dry skin. People with post-finasteride syndrome may experience depression and anxiety, cognitive impairment and suicidal thoughts.[14]

Post-finasteride syndrome may also have reduced levels of neurosteroids such as allopregnanolone in their cerebrospinal fluid. One study found that 1.4% developed persistent sexual dysfunction.[13]
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The central effects associated with the use of finasteride, include cognitive and affective/psychological changes. Yet, these effects are not well studied compared to AEs on sexual function, partly because of the implicit, but incorrect, assumption that finasteride does not target brain 5α-reductase. As in the present report, the self-reported central symptoms can include mental cloudiness, difficulties with attention/focus, and memory problems (Ganzer et al., 2015). There is also evidence of finasteride altering other complex cognitive behaviors, such as motivation and reward. This has been observed in case studies and clinical reports showing that finasteride can reduce symptoms across different neuropsychiatric or neurodegenerative disorders (reviewed in Traish et al., 2015; Paba et al., 2011). For example, finasteride reduced, tics, a major symptom, in Tourette Syndrome (Muroni, Paba, Puligheddu, Marrosu, & Bortolato, 2011). In another case study, problem gambling (as a potential adverse effect of treatment for Parkinson’s disease with dopaminergic agents) was reduced with finasteride administration (Bortolato et al., 2012). These studies demonstrate direct evidence to suggest that finasteride has effects on 5α-reductase in the brain.
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There is also ample evidence of adverse psychological or mood effects of finasteride following its discontinuation. In the recently published pilot study using a survey method to characterize psychological (and other) symptoms in men who used finasteride to treat MPB, the cohort reported high rates of psychological symptoms (Ganzer et al., 2015); these effects are much like what we report here using a different approach. Moreover, a recent report has corroborated and extended these results to assess specifically mood symptoms (Ganzer & Jacobs, 2016). Further, in a clinical study, significantly increased depression symptoms and suicidality were reported by three-quarters of the subject group that had discontinued finasteride, compared to about 10% of the control group (Irwig, 2012a). Among patients that have discontinued finasteride treatment, there was depression, mood disturbances, and changes in steroid levels in plasma and cerebrospinal fluid (Melcangi et al., 2013). Another study evaluated the hypothalamic-pituitary-gonadal (HPG) axis, irreversible suppression of SRD5A1 (5α-reductase gene), off-target suppression of androgen receptor (AR) action, effects on brain regions that regulate sexual function and mood, cognitive function, and sexual function in symptomatic finasteride users, asymptomatic finasteride users, and a control group (healthy men under 50 years of age; Basaria et al. 2016). Overall, Basaria et al. found no hormonal or genetic correlate as the causative factor for PFS. However, they observed subjective differences in personality/mood, sexual function, and cognitive function. Importantly, neural activity as determined by functional magnetic resonance imaging blood oxygen level-dependent (fMRI BOLD) activity, showed abnormal neural activity in regions associated with sexual function and major depression only in symptomatic finasteride users. Based on the comprehensive assessment by Basaria et al., it is likely that PFS may be due to a persistent rewiring of neural circuitry that may or may not have a hormonal correlate. Thus, these studies in people show that there are physical and central effects of finasteride that can be persistent, and the hormonal correlates have been hinted at and need further investigation.
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Whatever sides, it's worse being bald.
 
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gymislife said:
There is also ample evidence of adverse psychological or mood effects of finasteride following its discontinuation.
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well no fucking shit
 
calvitieddd said:
Ok so op this is your new place :

r/bald

r/bald:
reddit.com reddit.com

:feelskek:
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Peroxide said:
I heard that fin can damage your brain. How the fin exactly works with brain and which areas of brain can fin fuck up?
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I don't know about you guys but if I go bald in my early 20s I'll get depressed 100%, and the chance of getting depression from fin is like 1% so it's not a hard choice, atleast for me :D
 
gymislife said:
I don't know about you guys but if I go bald in my early 20s I'll get depressed 100%, and the chance of getting depression from fin is like 1% so it's not a hard choice, atleast for me :D
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Trust me I have insane hairloss at 22 and without fin I think I should taking jewpills (anti depressant)
 
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Schizoidcel said:
www.ncbi.nlm.nih.gov

The corpus cavernosum after treatment with dutasteride or finasteride: A histomorphometric study in a benign prostatic hyperplasia rodent model

Erectile dysfunction is a common side effect of finasteride and dutasteride treatments. The objective of this study was to investigate the structural changes in the penis using a benign prostatic hyperplasia (BPH) rodent model treated with dutasteride ...
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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I would still take it if i was a balding mouse.
 
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keep finning, keep winning
porn watchers 7 days a week x 365days a year will blame finn for loss of libido
Clinton
 
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waiting for the meme of the ‘fin is poison! i will never take fin’ then he’s NW7
 
keep finning keep winning
Finasteride
 
the fincope army summed it up pretty well

losing your hair is horrific and fin has the potential to be pretty bad too



fin does have the potential to effect a bunch of neurosteroids - hence the brain fog and mood sides that people experience

1609302295808


iirc the big one here is allopregnanolone

its not optimal but losing hair is a death sentence.
 
TurboFixer said:
the fincope army summed it up pretty well

losing your hair is horrific and fin has the potential to be pretty bad too



fin does have the potential to effect a bunch of neurosteroids - hence the brain fog and mood sides that people experience

View attachment 898244

iirc the big one here is allopregnanolone

its not optimal but losing hair is a death sentence.
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I bet you could take 5a-DHP and a low dose of HCG with finasteride and not get as many sides. And many Cabergoline.
 
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