TrueLabRat
Iron
- Joined
- Oct 22, 2025
- Posts
- 104
- Reputation
- 43
no this is not CJC-1295 and not Ipamorelin.
the peptide Im talking about is VSPPLTLGQLLS also known as Peptide P3.
many of you have probably heard of FGF in the context of height..
well amongst them, hides FGFR3 - one of the main height suppresors in our body, and in the field of FGF's, the ones that affects our height the most.
and also one of the core factors that determine a person's genetic height potential.
BUT the major problem of the inhibiton of FGFR3 is that most of the modern accesible medications that do it affectively are used for tumour prevention and th result is that they don't stirctly inhibit FGFR3 but inhibit ALL of the FGFR's which are essential for growth and the complete inhibition of all of them causes outrages risks.
but recently a treatment has been approved for children who suffer from chronically high levels of FGFR3
resulting in a very short statue - vosoritide.
a small molecule that effectively downregulates FGFR3 levels in the blood by activating the CNP pathway that upregulates SOX9 and downregulates FGFR3 resulting in a taller statue. the Problem? the treatment is offered for a price of 500,000$. not because it is that expensive to produce but because the field of the condition is very niche and affects a small population of the world. and for the exact same reason, no other medication has been approved for human trials in this field.
this is where P3 steps in.
the simple, barely recognised peptide made up of 12 cheap amino acids has been shown to effectively INHIBIT FGFR3 (not just downregulate) production in the body constantly thorugh out many instances and even completely prevented the certain death of an infant mouse with thanatophoric dysplasia a condition that causes mice to shortly die after birth as a result of their abnormally high FGFR3 levels in the blood.
what makes it so special?
1. shown to effectively operate when delivered systematically (IP injection) at very low doses (in mice trials)
2. has shown no toxicity at very high doses
3. is dirt cheap compared to other compounds with similar mechanisms
and the most impressive of the bunch -
4. has been proven to strictly inhibit FGFR3 and not other pathways which makes it one of a kind amongst its brothers.
as of now there arent any human trials and it is more than likely that it will stay this way in the future because of how huge companies operate when it comes to conditions of this kind.
so as of now, its long-term risks for height maxxing purposes remain unkown but it still remains as one of the if not the most promising compound by its mechanisms and its animal trials in the context of inhibiting FGFR3.
the peptide Im talking about is VSPPLTLGQLLS also known as Peptide P3.
many of you have probably heard of FGF in the context of height..
well amongst them, hides FGFR3 - one of the main height suppresors in our body, and in the field of FGF's, the ones that affects our height the most.
and also one of the core factors that determine a person's genetic height potential.
BUT the major problem of the inhibiton of FGFR3 is that most of the modern accesible medications that do it affectively are used for tumour prevention and th result is that they don't stirctly inhibit FGFR3 but inhibit ALL of the FGFR's which are essential for growth and the complete inhibition of all of them causes outrages risks.
but recently a treatment has been approved for children who suffer from chronically high levels of FGFR3
resulting in a very short statue - vosoritide.
a small molecule that effectively downregulates FGFR3 levels in the blood by activating the CNP pathway that upregulates SOX9 and downregulates FGFR3 resulting in a taller statue. the Problem? the treatment is offered for a price of 500,000$. not because it is that expensive to produce but because the field of the condition is very niche and affects a small population of the world. and for the exact same reason, no other medication has been approved for human trials in this field.
this is where P3 steps in.
the simple, barely recognised peptide made up of 12 cheap amino acids has been shown to effectively INHIBIT FGFR3 (not just downregulate) production in the body constantly thorugh out many instances and even completely prevented the certain death of an infant mouse with thanatophoric dysplasia a condition that causes mice to shortly die after birth as a result of their abnormally high FGFR3 levels in the blood.
what makes it so special?
1. shown to effectively operate when delivered systematically (IP injection) at very low doses (in mice trials)
2. has shown no toxicity at very high doses
3. is dirt cheap compared to other compounds with similar mechanisms
and the most impressive of the bunch -
4. has been proven to strictly inhibit FGFR3 and not other pathways which makes it one of a kind amongst its brothers.
as of now there arent any human trials and it is more than likely that it will stay this way in the future because of how huge companies operate when it comes to conditions of this kind.
so as of now, its long-term risks for height maxxing purposes remain unkown but it still remains as one of the if not the most promising compound by its mechanisms and its animal trials in the context of inhibiting FGFR3.
