GHK-CU, it's loss of potency issue and how you can fix it

HtnGymcel

HtnGymcel

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I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.


however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.
 
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I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.


however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.
BOTB
 
Good thread but JFL at not using PBS as mentioned in the linked thread. "But sterilization!" Low iqcels don't realize the chances of infection from using PBS is minimal. Even if you do get an infection, the extra copper from using PBS should heal it, GHK-CU heals wounds after all
 
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Good thread but JFL at not using PBS as mentioned in the linked thread. "But sterilization!" Low iqcels don't realize the chances of infection from using PBS is minimal. Even if you do get an infection, the extra copper from using PBS should heal it, GHK-CU heals wounds after all
Ur talking about an infection like its just nothing and not life threatening. Bro science remedy for it at aswell, yeah the copper will just heal the infection :feelshah:

I agree that PBS is vastly superior but u have to know what ur doing.
 
I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.


however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.
So what do you recommend to reconstitute it with?
 
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What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.
I'm so confused where do I keep the main vial refrigerated then? In my ass? The fridge is the only thing I have to refrigeratare things. :feelsgah:

Nice thread though
 
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Reactions: Blue Steel
I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.


however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.
Half wrong GHK-Cu is not simply going bad after seven days in the fridge and can still be effective if it is stored properly. The speed at which it loses potency is influenced mostly by factors such as light, air, and pH rather than time alone.
 
I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.


however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.
hmm i use my ghk cu with pbs around 16-17 days and still see some results:ogre:
 
I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.


however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.
I rly like ur content gng, but pbs is not necessary for ghk. It is a big misconception due to that one thread and its mostly speculations and not backed by studies
It does indeed degrade slightly slower if reconstituted in PBS, but the difference is so small you tend to use the entire vial before the difference becomes noticeable
 
I rly like ur content gng, but pbs is not necessary for ghk. It is a big misconception due to that one thread and its mostly speculations and not backed by studies
It does indeed degrade slightly slower if reconstituted in PBS, but the difference is so small you tend to use the entire vial before the difference becomes noticeable
Love your shit too bro
Sure but science is science. It's a fact that benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
 
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Love your shit too bro
Sure but science is science. It's a fact that benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
Yes Ur Right pbs is in General better, but the the Oxidation does not happen that quickly and its js a common misconception
And tbh ghk with pbs is not worth my effort for the bit more potency I am getting
U usually also tend to use up the vial bf the potency loss become noticable
 
Yes Ur Right pbs is in General better, but the the Oxidation does not happen that quickly and its js a common misconception
And tbh ghk with pbs is not worth my effort for the bit more potency I am getting
U usually also tend to use up the vial bf the potency loss bc noticable
Yeah i mean it starts degrading with time.
I also mix with bac i can't even bother getting pbs
 
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