GHK-CU, it's loss of potency issue and how you can fix it

[HtnGymcel]

I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.

How to properly use GHK-Cu

GHK-Cu, on paper, seems to be the single best looksmaxxing compound there is (perfect skin, anti-aging, surgery recovery, neurogenesis⁹,¹¹ etc)¹, yet no one seems to be reaping any of its benefits. What’s even more bizarre is that injection-related pain is massively reported, more consistently...

looksmax.org

however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.

 

[FlotPSL]

I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.

How to properly use GHK-Cu

GHK-Cu, on paper, seems to be the single best looksmaxxing compound there is (perfect skin, anti-aging, surgery recovery, neurogenesis⁹,¹¹ etc)¹, yet no one seems to be reaping any of its benefits. What’s even more bizarre is that injection-related pain is massively reported, more consistently...

looksmax.org

however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.

BOTB

 

[HtnGymcel]

BOTB

Not even close but thank you!

 

[SoNotFunny]

Good thread but JFL at not using PBS as mentioned in the linked thread. "But sterilization!" Low iqcels don't realize the chances of infection from using PBS is minimal. Even if you do get an infection, the extra copper from using PBS should heal it, GHK-CU heals wounds after all

 

[Whirr22222]

Good thread but JFL at not using PBS as mentioned in the linked thread. "But sterilization!" Low iqcels don't realize the chances of infection from using PBS is minimal. Even if you do get an infection, the extra copper from using PBS should heal it, GHK-CU heals wounds after all

Ur talking about an infection like its just nothing and not life threatening. Bro science remedy for it at aswell, yeah the copper will just heal the infection

I agree that PBS is vastly superior but u have to know what ur doing.

 

[ectomorpher]

I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.

How to properly use GHK-Cu

GHK-Cu, on paper, seems to be the single best looksmaxxing compound there is (perfect skin, anti-aging, surgery recovery, neurogenesis⁹,¹¹ etc)¹, yet no one seems to be reaping any of its benefits. What’s even more bizarre is that injection-related pain is massively reported, more consistently...

looksmax.org

however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.

So what do you recommend to reconstitute it with?

 

[Justakid]

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

I'm so confused where do I keep the main vial refrigerated then? In my ass? The fridge is the only thing I have to refrigeratare things.

Nice thread though

 

[Deleted member 241950]

I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.

How to properly use GHK-Cu

GHK-Cu, on paper, seems to be the single best looksmaxxing compound there is (perfect skin, anti-aging, surgery recovery, neurogenesis⁹,¹¹ etc)¹, yet no one seems to be reaping any of its benefits. What’s even more bizarre is that injection-related pain is massively reported, more consistently...

looksmax.org

however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.

Half wrong GHK-Cu is not simply going bad after seven days in the fridge and can still be effective if it is stored properly. The speed at which it loses potency is influenced mostly by factors such as light, air, and pH rather than time alone.

 

[afghanincel]

I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.

How to properly use GHK-Cu

GHK-Cu, on paper, seems to be the single best looksmaxxing compound there is (perfect skin, anti-aging, surgery recovery, neurogenesis⁹,¹¹ etc)¹, yet no one seems to be reaping any of its benefits. What’s even more bizarre is that injection-related pain is massively reported, more consistently...

looksmax.org

however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.

hmm i use my ghk cu with pbs around 16-17 days and still see some results

 

[Joe.789]

I recently posted a thread about the usage of a few peptides which included GHK-CU. I got a few answers which made me do some research, and if you are using GHK-Cu or planning to, this may be relevant.

Most peptides are mixed with BAC water (bacteriostatic water) because it contains a small amount of benzyl alcohol, which prevents bacteria growth and keeps the peptide sterile and stable for longer (usually up to 28 days).

In the case of GHK-CU, BAC water is not the best solution. Read this thread regarding what to use, as it is the best on here and the user made a way better thread than i ever could.

How to properly use GHK-Cu

GHK-Cu, on paper, seems to be the single best looksmaxxing compound there is (perfect skin, anti-aging, surgery recovery, neurogenesis⁹,¹¹ etc)¹, yet no one seems to be reaping any of its benefits. What’s even more bizarre is that injection-related pain is massively reported, more consistently...

looksmax.org

however, if you're planning on using BAC-water anyways, here is the best way to do it.

GHK-Cu in BAC water loses stability quickly because benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.
At 2–8 °C, expect 3–5 days of near-full activity, with noticeable degradation by day 7.

So basically after 7 days in the fridge, your GHK is ruined.

What you should do is:
Draw your 3–4 days’ worth of syringes, store those in the fridge (2–8 °C).
Keep the main vial refrigerated, not frozen, until it’s empty.
If you need to store solution longer than a week, make separate small vials or aliquots, freeze those once, and thaw each only once when needed.

Best solution is to read the thread linked to get the best result possible, however if you're in a situation where you already mixed it with bac, this may help.

I rly like ur content gng, but pbs is not necessary for ghk. It is a big misconception due to that one thread and its mostly speculations and not backed by studies
It does indeed degrade slightly slower if reconstituted in PBS, but the difference is so small you tend to use the entire vial before the difference becomes noticeable

 

[HtnGymcel]

I rly like ur content gng, but pbs is not necessary for ghk. It is a big misconception due to that one thread and its mostly speculations and not backed by studies
It does indeed degrade slightly slower if reconstituted in PBS, but the difference is so small you tend to use the entire vial before the difference becomes noticeable

Love your shit too bro
Sure but science is science. It's a fact that benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.

 

[Joe.789]

Love your shit too bro
Sure but science is science. It's a fact that benzyl alcohol and the copper ion both catalyze oxidation and peptide bond hydrolysis.

Yes Ur Right pbs is in General better, but the the Oxidation does not happen that quickly and its js a common misconception
And tbh ghk with pbs is not worth my effort for the bit more potency I am getting
U usually also tend to use up the vial bf the potency loss become noticable

 

[HtnGymcel]

Yes Ur Right pbs is in General better, but the the Oxidation does not happen that quickly and its js a common misconception
And tbh ghk with pbs is not worth my effort for the bit more potency I am getting
U usually also tend to use up the vial bf the potency loss bc noticable

Yeah i mean it starts degrading with time.
I also mix with bac i can't even bother getting pbs

 

[Jatt]

Keep the main vial refrigerated, not frozen, until it’s empty.

you think i should do this but with pbs water i think it would be the same

like imma do 3ml pbs water and inject that then preload in syringe 2mg each syringe

but problem would be hiding but i could find a hidden area tbh

 

[MastR]

Yeah i mean it starts degrading with time.
I also mix with bac i can't even bother getting pbs

Hey, so Ive read your thread & multiple others including the main one on using ghk cu with PBS and most of all of the replys on all of them, although I am left with a few questions. It would be so helpful if you could help me out on what im curious on.

My first question is, would freezing those extra vials keep them stable with the PBS indefinitely? and if not around how long of a time period could I keep them in with PBS while keeping each vial as effective copper wise & bacteria wise as possible? I read that with the fride & PBS they last around 17-20ish days.

2nd question, how many mg should I be injecting daily? Now I know that that could be a very varied answer but ive seen people be told that doing it at 2.5mg and even 5mg is not great because it isnt enough. So I was thinking on using 7.5/10mg daily, and want the confirmation that, that is an appropriate and surly effective amount. Ive also seen somebody say they get rid of their 100ml PBS after every reconstitution of their ghk cu because of safety and they buy a whole new one.

(it is cheap for them at €7 but isnt for me, and I would like to know if it makes perfect sense for me to just get the 100ml pbs for 5 vials of ghk cu then reconstitute and put them all in the freezer except 1, with the remaining 1 being put in the fridge.)

I deeply appreciate you reading all of this, and am thankful for any advise and insight given.

 

[Son of gigachad]

nice job bro, crucial info i been trying to find to no avail if true, copy pasting my ckmment from the other thread for any thoughts by anyone here , also researchpeptideseurope sells it (un reconstituted thankfully ) with third party COAs

"amazing thread brother , as someone who researched just about any supplement/peptide that exist, ghk cu is truly a silver bullet on paper for health Maxxing and looksmaxing. the amount of crucial genes it upregulates and downregulates is insane, and the way it drops as we age does suggest potential causality in aging itself once you understand its mechanistics, and with special emphasis on glycosaminoglycans and glycocalyx, but also bioavailable copper at the center of bioenergetics. AI also told me about PBS when i did my own research, but do you agree it is safe intranasally? alternatively , what about nanoliposomes by liposense sold by mcsformulas in the netherlands? seems promising even orally mechanistically no?"