GOONING LOWERS T BY 50%!!!

[Deleted member 19101]

TLDR IF YOU MASTURBATED EVERY OTHER DAY YOU ARE LOSING 30% - - 50% TESTOSTERONE FOR 48 HOURS WHICH MEANS IF YOU NEVER STOPPED MASTURBATING EVERY DAY YOU LOST 30% OF YOUR TOTAL TEST, AT LEAST!!!

 

[futureashtray]

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TLDR IF YOU MASTURBATED EVERY OTHER DAY YOU ARE LOSING 30% - - 50% TESTOSTERONE FOR 48 HOURS WHICH MEANS IF YOU NEVER STOPPED MASTURBATING EVERY DAY YOU LOST 30% OF YOUR TOTAL TEST, AT LEAST!!!

I am not a rat

 

[alurmo]

im not a fag so this is false

 

[Deleted member 19101]

I am not a rat

Theres a reason they test rats for human medications… we have similar endocrine systems

 

[futureashtray]

Theres a reason they test rats for human medications… we have similar endocrine systems

I AM NOT A RAT

 

[ICXCLuvr]

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TLDR IF YOU MASTURBATED EVERY OTHER DAY YOU ARE LOSING 30% - - 50% TESTOSTERONE FOR 48 HOURS WHICH MEANS IF YOU NEVER STOPPED MASTURBATING EVERY DAY YOU LOST 30% OF YOUR TOTAL TEST, AT LEAST!!!

ii will never goon.

 

[Deleted member 19101]

ii will never goon.

 

[Prettyboymog]

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TLDR IF YOU MASTURBATED EVERY OTHER DAY YOU ARE LOSING 30% - - 50% TESTOSTERONE FOR 48 HOURS WHICH MEANS IF YOU NEVER STOPPED MASTURBATING EVERY DAY YOU LOST 30% OF YOUR TOTAL TEST, AT LEAST!!!

Wat bout edging? I don’t watch porn tho

 

[mog_or_be_mogged]

chad jerks off 15 times every day and loses 0 testosterone

 

[Latinolooksmaxxer]

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TLDR IF YOU MASTURBATED EVERY OTHER DAY YOU ARE LOSING 30% - - 50% TESTOSTERONE FOR 48 HOURS WHICH MEANS IF YOU NEVER STOPPED MASTURBATING EVERY DAY YOU LOST 30% OF YOUR TOTAL TEST, AT LEAST!!!

study should be done with humans though

vast majority of other mammals in adulthood go in heat and only engage in sexual activities in that period

but great apes have consistently high sexual libido - chimpanzees for an example constantly masturbate. queer "scientific divulgators" and feministcucks use to focus on female chimpanzee maturbation when talking about it but the statistics are similar to our species - the vast majority of male chimpanzees (nearly 90%) masturbate and only a fraction of the females masturbate (around 1 third) and with less frequency

the bigger the sexual organs compared to the body the more the great apes masturbate. for an example gorillas have microdicks so they dont masturbate as often, but chimpanzees have almost the same dick and balls size as us and so they masturbate quite often

and we have the biggest sexual organs amongst all great apes and we masturbate the most

 

[Deleted member 19101]

study should be done with humans though

vast majority of other mammals in adulthood go in heat and only engage in sexual activities in that period

but great apes have consistently high sexual libido - chimpanzees for an example constantly masturbate. queer "scientific divulgators" and feministcucks use to focus on female chimpanzee maturbation when talking about it but the statistics are similar to our species - the vast majority of male chimpanzees (nearly 90%) masturbate and only a fraction of the females masturbate (around 1 third) and with less frequency

the bigger the sexual organs compared to the body the more the great apes masturbate. for an example gorillas have microdicks so they dont masturbate as often, but chimpanzees have almost the same dick and balls size as us and so they masturbate quite often

and we have the biggest sexual organs amongst all great apes and we masturbate the most

The ligand binding domain of human AR (aa 661-920) shares 100% aa sequence identity with mouse and rat AR. AR (Androgen receptor) is a 99 kDa (predicted) member of the NR3 subfamily, nuclear hormone receptor family of proteins. Due to a high number of Gln and Pro residues, it runs anomalously at 100‑120 kDa in SDS-PAGE. It is widely expressed, being found in neurons, endothelial cells, osteoblasts, chrondrocytes, mascrophages, adipocytes, and prostate epithelium. Human AR is 919 amino acids (aa) in length. It contains three discrete domains: a "modulating" N‑terminus (aa 1‑553) that is rich in Gln, Pro and Gly, a Zn-finger DNA-binding region (aa 554‑635), and a ligand-binding domain (aa 672‑917). AR is highly polymorphic at the N‑terminus, with total Gln and Gly residues differing by seven or more residues among individuals. Multiple potential splice forms exist, including an alternative start site at Met189 and a seven aa substitution for aa 1‑538 that generates a 45 kDa isoform. AR does homodimerize, apparently with multiple isotypes. Over aa 661‑920, human and mouse are identical in aa sequence.

https://www.rndsystems.com/products/human-mouse-rat-androgen-r-nr3c4-antibody_af5876#:~:text=The%20ligand%20binding%20domain%20of,are%20identical%20in%20aa%20sequence.

https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1749-6632.1989.tb25887.x

we share very similar androgen receptors, so that means the same effect of the rat masturbation studies would apply to humans.

 

[Latinolooksmaxxer]

The ligand binding domain of human AR (aa 661-920) shares 100% aa sequence identity with mouse and rat AR. AR (Androgen receptor) is a 99 kDa (predicted) member of the NR3 subfamily, nuclear hormone receptor family of proteins. Due to a high number of Gln and Pro residues, it runs anomalously at 100‑120 kDa in SDS-PAGE. It is widely expressed, being found in neurons, endothelial cells, osteoblasts, chrondrocytes, mascrophages, adipocytes, and prostate epithelium. Human AR is 919 amino acids (aa) in length. It contains three discrete domains: a "modulating" N‑terminus (aa 1‑553) that is rich in Gln, Pro and Gly, a Zn-finger DNA-binding region (aa 554‑635), and a ligand-binding domain (aa 672‑917). AR is highly polymorphic at the N‑terminus, with total Gln and Gly residues differing by seven or more residues among individuals. Multiple potential splice forms exist, including an alternative start site at Met189 and a seven aa substitution for aa 1‑538 that generates a 45 kDa isoform. AR does homodimerize, apparently with multiple isotypes. Over aa 661‑920, human and mouse are identical in aa sequence.

https://www.rndsystems.com/products/human-mouse-rat-androgen-r-nr3c4-antibody_af5876#:~:text=The%20ligand%20binding%20domain%20of,are%20identical%20in%20aa%20sequence.

https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1749-6632.1989.tb25887.x

we share very similar androgen receptors, so that means the same effect of the rat masturbation studies would apply to humans.

makes sense but you dont lose total or free testosterone (as you imply in OP) but only receptors in the brain

effects are different amongst the two as theres androgen receptors in other tissues such as skeletal and muscular

 

[Deleted member 19101]

makes sense but you dont lose total or free testosterone (as you imply in OP) but only receptors in the brain

simplified from chatgpt:

The androgen receptor (AR) is a protein found in many types of cells in the body, like nerve cells, blood vessel cells, bone cells, and prostate cells. AR helps cells respond to hormones, especially male hormones like testosterone. The human AR protein is made of 919 smaller building blocks called amino acids (aa). It has three main parts: the first part (aa 1-553) helps control the protein’s activity, the middle part (aa 554-635) binds to DNA, and the last part (aa 672-917) binds to hormones.

In humans, this protein can change slightly between different people, especially in the first part, because of differences in some amino acids. There are also different versions of the AR protein that come from the same gene. Some of these versions start at a different place in the sequence or have small changes in the amino acids. One version is much smaller, weighing about 45 kDa.

Even though there are these differences, the part of the AR protein that binds to hormones (aa 661-920) is exactly the same in humans, mice, and rats. This section of the protein is important because it allows the protein to work the same way in these different species.

 

[Deleted member 91529]

i masturbate like 10 times a day, dont sleep at all, and eat chips all day

 

[Latinolooksmaxxer]

simplified from chatgpt:

The androgen receptor (AR) is a protein found in many types of cells in the body, like nerve cells, blood vessel cells, bone cells, and prostate cells. AR helps cells respond to hormones, especially male hormones like testosterone. The human AR protein is made of 919 smaller building blocks called amino acids (aa). It has three main parts: the first part (aa 1-553) helps control the protein’s activity, the middle part (aa 554-635) binds to DNA, and the last part (aa 672-917) binds to hormones.

In humans, this protein can change slightly between different people, especially in the first part, because of differences in some amino acids. There are also different versions of the AR protein that come from the same gene. Some of these versions start at a different place in the sequence or have small changes in the amino acids. One version is much smaller, weighing about 45 kDa.

Even though there are these differences, the part of the AR protein that binds to hormones (aa 661-920) is exactly the same in humans, mice, and rats. This section of the protein is important because it allows the protein to work the same way in these different species.

If masturbation leads to a reduction of androgen receptor activity due to some mechanism that impairs a protein found in all receptors then it would impair all receptors

but the study provided cites 'specific regions of the brain' so I'd assume its more of a mechanism to regulate libido and dont make the animal lose itself in mating than an overall entire body effect on adrogen receptors

 

[FascisstChad]

Yes goon, goon everyday

 

[Deleted member 19101]

If masturbation leads to a reduction of androgen receptor activity due to some mechanism that impairs a protein found in all receptors then it would impair all receptors

but the study provided cites 'specific regions of the brain' so I'd assume its more of a mechanism to regulate libido and dont make the animal lose itself in mating than an overall entire body effect on adrogen receptors

its interesting non the less

 

[Latinolooksmaxxer]

its interesting non the less

ill read the entire study while gooning for maximum iqmaxxing results

 

[NZb6Air]

i masturbate like 10 times a day, dont sleep at all, and eat chips all day

*pretends to be shocked*

 

[Deleted member 19101]

If masturbation leads to a reduction of androgen receptor activity due to some mechanism that impairs a protein found in all receptors then it would impair all receptors

but the study provided cites 'specific regions of the brain' so I'd assume its more of a mechanism to regulate libido and dont make the animal lose itself in mating than an overall entire body effect on adrogen receptors

did some chat gpt research and even if the brain has reduced AR it will still affect puberty as stated here:
Androgen receptors (ARs) in the brain are important for several processes during puberty, influencing both physical and behavioral changes. In particular, ARs in regions like the hypothalamus and amygdala regulate the release of hormones and modulate sexual behavior, mood, and other physical characteristics. Here’s how ARs in the brain contribute to physical changes during puberty:

1. **Hormonal Regulation**: ARs in the hypothalamus play a crucial role in the release of gonadotropin-releasing hormone (GnRH). This hormone signals the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which stimulate the testes to produce testosterone. The increase in testosterone then drives the physical changes associated with puberty, such as muscle growth, voice deepening, and the development of secondary sexual characteristics like body hair.

2. **Growth Spurt**: The increase in testosterone, mediated by AR activity in the brain, leads to a significant growth spurt. This is partly due to ARs influencing the production of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), which are key regulators of bone growth and overall height during puberty.

3. **Muscle Development**: ARs in the brain influence testosterone levels that impact muscle growth. Testosterone binds to ARs in muscle tissues, enhancing protein synthesis and muscle mass during puberty, resulting in the characteristic increase in muscle size and strength in males.

4. **Body Composition and Fat Distribution**: ARs also contribute to changes in fat distribution. During puberty, testosterone causes fat to accumulate more in areas like the abdomen rather than the hips and thighs, which is a male-specific pattern. These changes are regulated by androgen receptor activity affecting hormonal levels and their action on fat tissue.

5. **Bone Maturation**: ARs indirectly support the fusion of growth plates in bones, leading to the end of height growth as puberty concludes. This is driven by the increased testosterone levels orchestrated by brain AR activity.

In summary, ARs in the brain are crucial for regulating testosterone production and release, which in turn drives the various physical changes seen during puberty, including muscle and bone growth, changes in fat distribution, and the onset of male secondary sexual characteristics【12†source】【13†source】.


in conclusion my original thesis is correct!!!

 

[Deleted member 19101]

Theoretically, if someone were to engage in masturbation every day without sufficient recovery time, it could potentially lead to a prolonged reduction in androgen receptor (AR) density, particularly in certain brain regions. This is based on findings from studies in rats, like the 2007 study, which showed that AR density in the brain decreased by 30-50% for up to 48 hours after sexual activity.

If this reduction happens daily, it might create a situation where AR levels are consistently lower, potentially affecting hormone signaling, as ARs are crucial for mediating testosterone’s effects on the body, including during puberty. However, whether this would have long-term consequences or significantly impair physical development is not entirely clear, particularly in humans.

There are a few important considerations:
1. **Recovery**: The rat study showed that AR density typically recovers after about 48 hours. If masturbation occurs too frequently, recovery time might not be sufficient, leading to more sustained reductions in AR density.
2. **Species Differences**: Human physiology can differ from rats, so it's uncertain whether humans would experience the same degree of AR reduction or the same time course for recovery.
3. **Context of Puberty**: Since puberty involves complex hormonal regulation and growth, a continuous reduction in AR density might interfere with the full response to testosterone, potentially slowing physical changes. However, human studies on this specific effect are lacking.

In summary, while daily masturbation could theoretically prevent AR density from fully recovering, leading to sustained lower AR levels, the actual impact on puberty or long-term development remains speculative without more evidence from human studies.


TLDR IF YOU GOON EVERY DAY!

IN THEORY YOU COULD BE REDUCING YOUR AR DENSITY AND IT WOULD RECOVER UNTIL AT LEAST 2 DAY OF NO MASTURBATION!

so for every one who masturbates every day or every other day you are ruining your puberty

 

[Deleted member 91529]

*pretends to be shocked*

and im still mogging on u lol