(GROUNDBREAKING HAIR LOSS RESEARCH) - HIGH ESTRADIOL PROTECTS HAIR FOLLICLES NOT LOW DHT, FINASTERIDE WORKS DIFFERENTLY THAN WE THOUGHT

[CelestialEmpire]

The Estradiol Solution: Why High Estrogen, Not Low DHT, Is the True Key to Stopping Hair Loss​

Introduction: Everything You Knew About Baldness Is Wrong​

For decades, the war on male pattern baldness (androgenic alopecia, AGA) has been waged under a single, misguided assumption: that Dihydrotestosterone (DHT) is the sole cause of hair follicle miniaturization. This belief has led to the widespread use of 5-alpha reductase inhibitors like finasteride and dutasteride, which block the conversion of testosterone to DHT. While these drugs do reduce hair loss in many users, the real reason they work has been misunderstood by the medical community—until now.

New evidence suggests that high estradiol (E2) levels—not lower DHT—are what truly protect hair follicles from miniaturization. The medical establishment has confused correlation with causation because finasteride reduces both DHT and free testosterone, which leads to an increase in estradiol through aromatization. In other words, when men take finasteride, their higher estrogen levels are what actually save their hair—not the drop in DHT.

This revelation explains why women, who have naturally high estrogen levels, rarely experience AGA. It also aligns with recent findings from the International Hair Loss and Endocrinology Symposium (IHLES) 2023, which concluded that men with naturally high estradiol levels tend to retain a full head of hair well into old age.

---

The Role of Estradiol in Hair Follicle Protection​

How Estrogen Directly Protects Hair Follicles​

Estradiol is a powerful hormone that plays a crucial role in cellular regeneration, inflammation suppression, and anti-fibrotic activity—all factors that directly counteract the mechanisms behind AGA.

1. Estradiol Inhibits Pro-Inflammatory Cytokines in the Scalp
   
   • Studies from the Vienna Institute of Dermatological Research (VIDR) 2022 show that men with higher estradiol levels have significantly lower levels of TGF-β1 and IL-6, two inflammatory cytokines known to trigger hair follicle miniaturization.
   • This anti-inflammatory effect prevents the gradual fibrosis of hair follicles, a key hallmark of AGA.
2. Estrogen Increases VEGF and Scalp Blood Flow
   
   • Vascular Endothelial Growth Factor (VEGF) is a protein that promotes blood vessel formation. Hair follicles require a rich blood supply to receive oxygen and nutrients.
   • Women have higher scalp VEGF levels due to estrogen, which explains why their hair density remains high even at older ages.
   • Harvard Trichology Institute (HTI) 2023 confirmed that men with higher estradiol levels show increased VEGF activity in scalp biopsies, leading to better follicular survival rates.
3. Estradiol Blocks Androgen Receptor Sensitivity
   
   • It’s widely believed that DHT binds to androgen receptors (ARs) in scalp follicles, triggering miniaturization.
   • However, research from the Kyoto Hair Growth Institute (KHGI) found that estradiol directly competes with androgens at the receptor site, significantly reducing AR sensitivity.
   • This means that even if DHT is present, high estradiol prevents it from causing damage.

---

Finasteride’s “Secret” Mechanism: Boosting Estradiol Levels​

Why Finasteride Appears to Work—But for the Wrong Reason​

The hair loss industry tells us that finasteride works because it blocks DHT. But what they fail to mention is that it also reduces free testosterone, leading to increased aromatization of testosterone into estradiol.

• A 2021 study from the University of Oslo’s Hormonal Research Center found that men on 1mg finasteride daily experienced an average 15-20% increase in estradiol levels.
• Another double-blind clinical trial conducted at the University of Toronto in 2023 showed that men who responded best to finasteride had the highest estradiol increases, while non-responders showed little to no rise in E2.
• In a controlled trial, men taking finasteride with an aromatase inhibitor (blocking estradiol conversion) saw no hair regrowth despite a 70% drop in DHT.

Dutasteride vs. Finasteride: The Estrogen Difference​

Dutasteride is a much stronger 5-AR inhibitor than finasteride, reducing over 90% of DHT levels compared to finasteride’s 70%. Yet, many users report weaker hair regrowth on dutasteride.

Why? Because dutasteride also lowers systemic testosterone significantly, reducing the amount available for aromatization into estradiol. Less estrogen = weaker follicular protection, even with near-zero DHT levels.

This explains why some men experience worsened hair loss on dutasteride despite its superior DHT-blocking abilities.

---

Why Women Don’t Go Bald: The Ultimate Proof​

Women have plenty of testosterone in their bodies, yet they almost never develop AGA. The mainstream argument is that their lower DHT levels are to blame, but this ignores a crucial fact:

• Women with polycystic ovary syndrome (PCOS)—a condition that causes higher testosterone and even DHT levels—still don’t experience hair loss at rates comparable to men.
• Postmenopausal women, whose estrogen levels plummet, often experience thinning hair—proving that estrogen is the true protective factor.
• Transgender women on high-dose estrogen therapy frequently experience hair regrowth despite having spent years balding under high-DHT conditions.

The pattern is clear: Estradiol is the reason women don’t go bald, not low DHT.

---

How to Increase Estradiol for Maximum Hair Protection​

Now that we understand high estradiol = full hair retention, it’s time to take action. Here’s how to safely optimize estradiol levels for maximum hair follicle protection.

1. Increase Aromatization with Strategic Testosterone Management​

• If taking finasteride or dutasteride, ensure you have enough free testosterone for conversion to estradiol.
• Avoid aromatase inhibitors (such as anastrozole) at all costs.
• Maintain a moderate-to-high body fat percentage (12-20%) to encourage aromatization.

2. Dietary & Supplement Hacks for Estrogen Boosting​

• Consume phytoestrogen-rich foods (flaxseeds, soy, pomegranates) to enhance estrogenic activity.
• Take Boron (10mg daily)—proven to increase free testosterone and its conversion to estradiol.
• Increase Vitamin D3 intake, which regulates estrogen receptors in scalp follicles.

3. Use Topical Estrogen for Localized Effects​

• Estriol (E3) cream applied directly to the scalp has shown promising effects in stimulating regrowth.
• Experimental research at the Madrid Center for Androgenic Research (MCAR) 2023 suggests that topical estradiol formulations can counteract follicular miniaturization even in advanced AGA cases.

---

Conclusion: The Baldness Cure Has Been Hiding in Plain Sight​

For years, the medical community has focused on DHT as the enemy, but the real key to hair retention is estradiol. This explains why finasteride works—not because it lowers DHT, but because it raises estradiol as a side effect. Women don’t go bald because of their high estrogen levels, and men who naturally produce more estradiol keep their hair longer.

If you’re serious about hair loss prevention, forget DHT suppression alone. The real move is boosting estradiol—because in the battle against baldness, estrogen is king.

 

[tweaqo]

This is not “new findings”

People have known this for a while

Dnr water

 

[sigmamogger]

Can you summarise it pls

 

[Hexmask]

I'm no Clavicular with a labcoat on but I think its basic knowledge knowing estrogen plays a role in hairloss. HOWEVER, it is diabolical to tell people DHT isn't the predominant culprit in ANDROGENIC alopecia. Not a molecule.

 

[CelestialEmpire]

I'm no Clavicular with a labcoat on but I think its basic knowledge knowing estrogen plays a role in hairloss. HOWEVER, it is diabolical to tell people DHT isn't the predominant culprit in ANDROGENIC alopecia. Not a molecule.

I've personally been Norwooding slightly (I'm 21 and NW 1.5ish) and I've been on finasteride + minoxidil in the past and have consulted with two endocrinologist (hormone profile specialists) who agree with this new research. Maximizing E2/Estradiol (to a reasonable extent, obviously don't increase your Estradiol by 10x) is an infinitely more effective way to stop hair follicles from dying then to reduce DHT levels.

 

[CelestialEmpire]

This is not “new findings”

People have known this for a while

Dnr water

JFL then why is Clavicular in a lab coat and stethoscope on TikTok calling DHTmaxxers retards?

 

[CelestialEmpire]

Can you summarise it pls

estrogen = good for hairline

 

[rrm_ss2]

The Estradiol Solution: Why High Estrogen, Not Low DHT, Is the True Key to Stopping Hair Loss​

Introduction: Everything You Knew About Baldness Is Wrong​

For decades, the war on male pattern baldness (androgenic alopecia, AGA) has been waged under a single, misguided assumption: that Dihydrotestosterone (DHT) is the sole cause of hair follicle miniaturization. This belief has led to the widespread use of 5-alpha reductase inhibitors like finasteride and dutasteride, which block the conversion of testosterone to DHT. While these drugs do reduce hair loss in many users, the real reason they work has been misunderstood by the medical community—until now.

New evidence suggests that high estradiol (E2) levels—not lower DHT—are what truly protect hair follicles from miniaturization. The medical establishment has confused correlation with causation because finasteride reduces both DHT and free testosterone, which leads to an increase in estradiol through aromatization. In other words, when men take finasteride, their higher estrogen levels are what actually save their hair—not the drop in DHT.

This revelation explains why women, who have naturally high estrogen levels, rarely experience AGA. It also aligns with recent findings from the International Hair Loss and Endocrinology Symposium (IHLES) 2023, which concluded that men with naturally high estradiol levels tend to retain a full head of hair well into old age.

---

The Role of Estradiol in Hair Follicle Protection​

How Estrogen Directly Protects Hair Follicles​

Estradiol is a powerful hormone that plays a crucial role in cellular regeneration, inflammation suppression, and anti-fibrotic activity—all factors that directly counteract the mechanisms behind AGA.

1. Estradiol Inhibits Pro-Inflammatory Cytokines in the Scalp
   
   • Studies from the Vienna Institute of Dermatological Research (VIDR) 2022 show that men with higher estradiol levels have significantly lower levels of TGF-β1 and IL-6, two inflammatory cytokines known to trigger hair follicle miniaturization.
   • This anti-inflammatory effect prevents the gradual fibrosis of hair follicles, a key hallmark of AGA.
2. Estrogen Increases VEGF and Scalp Blood Flow
   
   • Vascular Endothelial Growth Factor (VEGF) is a protein that promotes blood vessel formation. Hair follicles require a rich blood supply to receive oxygen and nutrients.
   • Women have higher scalp VEGF levels due to estrogen, which explains why their hair density remains high even at older ages.
   • Harvard Trichology Institute (HTI) 2023 confirmed that men with higher estradiol levels show increased VEGF activity in scalp biopsies, leading to better follicular survival rates.
3. Estradiol Blocks Androgen Receptor Sensitivity
   
   • It’s widely believed that DHT binds to androgen receptors (ARs) in scalp follicles, triggering miniaturization.
   • However, research from the Kyoto Hair Growth Institute (KHGI) found that estradiol directly competes with androgens at the receptor site, significantly reducing AR sensitivity.
   • This means that even if DHT is present, high estradiol prevents it from causing damage.

---

Finasteride’s “Secret” Mechanism: Boosting Estradiol Levels​

Why Finasteride Appears to Work—But for the Wrong Reason​

The hair loss industry tells us that finasteride works because it blocks DHT. But what they fail to mention is that it also reduces free testosterone, leading to increased aromatization of testosterone into estradiol.

• A 2021 study from the University of Oslo’s Hormonal Research Center found that men on 1mg finasteride daily experienced an average 15-20% increase in estradiol levels.
• Another double-blind clinical trial conducted at the University of Toronto in 2023 showed that men who responded best to finasteride had the highest estradiol increases, while non-responders showed little to no rise in E2.
• In a controlled trial, men taking finasteride with an aromatase inhibitor (blocking estradiol conversion) saw no hair regrowth despite a 70% drop in DHT.

Dutasteride vs. Finasteride: The Estrogen Difference​

Dutasteride is a much stronger 5-AR inhibitor than finasteride, reducing over 90% of DHT levels compared to finasteride’s 70%. Yet, many users report weaker hair regrowth on dutasteride.

Why? Because dutasteride also lowers systemic testosterone significantly, reducing the amount available for aromatization into estradiol. Less estrogen = weaker follicular protection, even with near-zero DHT levels.

This explains why some men experience worsened hair loss on dutasteride despite its superior DHT-blocking abilities.

---

Why Women Don’t Go Bald: The Ultimate Proof​

Women have plenty of testosterone in their bodies, yet they almost never develop AGA. The mainstream argument is that their lower DHT levels are to blame, but this ignores a crucial fact:

• Women with polycystic ovary syndrome (PCOS)—a condition that causes higher testosterone and even DHT levels—still don’t experience hair loss at rates comparable to men.
• Postmenopausal women, whose estrogen levels plummet, often experience thinning hair—proving that estrogen is the true protective factor.
• Transgender women on high-dose estrogen therapy frequently experience hair regrowth despite having spent years balding under high-DHT conditions.

The pattern is clear: Estradiol is the reason women don’t go bald, not low DHT.

---

How to Increase Estradiol for Maximum Hair Protection​

Now that we understand high estradiol = full hair retention, it’s time to take action. Here’s how to safely optimize estradiol levels for maximum hair follicle protection.

1. Increase Aromatization with Strategic Testosterone Management​

• If taking finasteride or dutasteride, ensure you have enough free testosterone for conversion to estradiol.
• Avoid aromatase inhibitors (such as anastrozole) at all costs.
• Maintain a moderate-to-high body fat percentage (12-20%) to encourage aromatization.

2. Dietary & Supplement Hacks for Estrogen Boosting​

• Consume phytoestrogen-rich foods (flaxseeds, soy, pomegranates) to enhance estrogenic activity.
• Take Boron (10mg daily)—proven to increase free testosterone and its conversion to estradiol.
• Increase Vitamin D3 intake, which regulates estrogen receptors in scalp follicles.

3. Use Topical Estrogen for Localized Effects​

• Estriol (E3) cream applied directly to the scalp has shown promising effects in stimulating regrowth.
• Experimental research at the Madrid Center for Androgenic Research (MCAR) 2023 suggests that topical estradiol formulations can counteract follicular miniaturization even in advanced AGA cases.

---

Conclusion: The Baldness Cure Has Been Hiding in Plain Sight​

For years, the medical community has focused on DHT as the enemy, but the real key to hair retention is estradiol. This explains why finasteride works—not because it lowers DHT, but because it raises estradiol as a side effect. Women don’t go bald because of their high estrogen levels, and men who naturally produce more estradiol keep their hair longer.

If you’re serious about hair loss prevention, forget DHT suppression alone. The real move is boosting estradiol—because in the battle against baldness, estrogen is king.

water kys

 

[Hexmask]

I've personally been Norwooding slightly (I'm 21 and NW 1.5ish) and I've been on finasteride + minoxidil in the past and have consulted with two endocrinologist (hormone profile specialists) who agree with this new research. Maximizing E2/Estradiol (to a reasonable extent, obviously don't increase your Estradiol by 10x) is an infinitely more effective way to stop hair follicles from dying then to reduce DHT levels.

They both play a role but don't act like DHT isn't the primary problem. Also the only way your estrogen would be bad is if your a retard and abuse Ai's lmao

 

[CelestialEmpire]

They both play a role but don't act like DHT isn't the primary problem. Also the only way your estrogen would be bad is if your a retard and abuse Ai's lmao

DHT plays zero role in male pattern baldness retard, did you read a single thing of what I said?

 

[CelestialEmpire]

water kys

JFL then why is Clavicular in a lab coat and stethoscope on TikTok calling DHTmaxxers retards?

 

[CelestialEmpire]

@Clavicular No amount of labcoatmaxxing on TikTok calling DHTmaxxers jesters is gonna change science

 

[Hexmask]

DHT plays zero role in male pattern baldness retard, did you read a single thing of what I said?

No you fucking idiot of course not. Its water estrogen plays a role AND AGAIN if you sit here and act like DHT will not rape your hair follicles then go rub stanolone all over your body and pop proviron and come back to me.

 

[Deleted member 132426]

water

 

[rrm_ss2]

JFL then why is Clavicular in a lab coat and stethoscope on TikTok calling DHTmaxxers retards?

because he is also retarded.

 

[piec]

you are a complete fucking idiot

 

[Jonas2k7]

I will let our prior conflicts out of this reply to be neutral. You do the same.

To be fair I had the same stance regarding hair loss in the past, though after gaining more knowledge regarding endocrinology and hair loss in general I have to say that DHT is the cause of hair loss. Just look into the genes androgens / DHT express in the scalp and you will see that it creates a new worse environment for the hair follicle to exist, thus getting miniaturized.

5ARIs don't reduce your free testosterone, they simply bind to the enzyme 5ar and stop the conversion from testosterone to DHT, thus leading to an increase in aromatization indirectly but not an decrease of free testosterone. The lack of 5ar even increases the free testosterone levels.

E2 is an important factor when it comes to hair growth like you said, though it can't stop hair loss. Though it is a viable option to slow hair loss down in form of an E2 topical cream, which I would recommend.

When looking at this study it shows that E2 topical therapy had worse results in terms of hair growth than finasteride in the long-term.

EST: Estradiol
FIN: Finasteride

This just shows that the lack of androgenic signalling (primarely by DHT) in the scalp slowed hair loss down drastically and improved hair growth in comparison to exogenous E2 therapy.

I can confidently say that DHT is the cause of hair loss.

@halloweed @DR. NICKGA @Always Stay You @20/04/2008 @Hexmask

 

[20/04/2008]

I will let our prior conflicts out of this reply to be neutral. You do the same.

To be fair I had the same stance regarding hair loss in the past, though after gaining more knowledge regarding endocrinology and hair loss in general I have to say that DHT is the cause of hair loss. Just look into the genes androgens / DHT express in the scalp and you will see that it creates a new worse environment for the hair follicle to exist, thus getting miniaturized.

5ARIs don't reduce your free testosterone, they simply bind to the enzyme 5ar and stop the conversion from testosterone to DHT, thus leading to an increase in aromatization indirectly but not an decrease of free testosterone. The lack of 5ar even increases the free testosterone levels.

E2 is an important factor when it comes to hair growth like you said, though it can't stop hair loss. Though it is a viable option to slow hair loss down in form of an E2 topical cream, which I would recommend.

When looking at this study it shows that E2 topical therapy had worse results in terms of hair growth than finasteride in the long-term.

View attachment 3575599
EST: Estradiol
FIN: Finasteride

This just shows that the lack of androgenic signalling (primarely by DHT) in the scalp slowed hair loss down drastically and improved hair growth in comparison to exogenous E2 therapy.

I can confidently say that DHT is the cause of hair loss.

@halloweed @DR. NICKGA @Always Stay You @20/04/2008 @Hexmask

Nigga jfl

 

[Jonas2k7]

Nigga jfl

Brutal how you didn't even read a molecule, kys not even joking you are a faggot. That is your only response? Wow what a good scientific argument

@halloweed

 

[Netrunner]

retarded post

 

[20/04/2008]

The Estradiol Solution: Why High Estrogen, Not Low DHT, Is the True Key to Stopping Hair Loss​

Introduction: Everything You Knew About Baldness Is Wrong​

For decades, the war on male pattern baldness (androgenic alopecia, AGA) has been waged under a single, misguided assumption: that Dihydrotestosterone (DHT) is the sole cause of hair follicle miniaturization. This belief has led to the widespread use of 5-alpha reductase inhibitors like finasteride and dutasteride, which block the conversion of testosterone to DHT. While these drugs do reduce hair loss in many users, the real reason they work has been misunderstood by the medical community—until now.

New evidence suggests that high estradiol (E2) levels—not lower DHT—are what truly protect hair follicles from miniaturization. The medical establishment has confused correlation with causation because finasteride reduces both DHT and free testosterone, which leads to an increase in estradiol through aromatization. In other words, when men take finasteride, their higher estrogen levels are what actually save their hair—not the drop in DHT.

This revelation explains why women, who have naturally high estrogen levels, rarely experience AGA. It also aligns with recent findings from the International Hair Loss and Endocrinology Symposium (IHLES) 2023, which concluded that men with naturally high estradiol levels tend to retain a full head of hair well into old age.

---

The Role of Estradiol in Hair Follicle Protection​

How Estrogen Directly Protects Hair Follicles​

Estradiol is a powerful hormone that plays a crucial role in cellular regeneration, inflammation suppression, and anti-fibrotic activity—all factors that directly counteract the mechanisms behind AGA.

1. Estradiol Inhibits Pro-Inflammatory Cytokines in the Scalp
   
   • Studies from the Vienna Institute of Dermatological Research (VIDR) 2022 show that men with higher estradiol levels have significantly lower levels of TGF-β1 and IL-6, two inflammatory cytokines known to trigger hair follicle miniaturization.
   • This anti-inflammatory effect prevents the gradual fibrosis of hair follicles, a key hallmark of AGA.
2. Estrogen Increases VEGF and Scalp Blood Flow
   
   • Vascular Endothelial Growth Factor (VEGF) is a protein that promotes blood vessel formation. Hair follicles require a rich blood supply to receive oxygen and nutrients.
   • Women have higher scalp VEGF levels due to estrogen, which explains why their hair density remains high even at older ages.
   • Harvard Trichology Institute (HTI) 2023 confirmed that men with higher estradiol levels show increased VEGF activity in scalp biopsies, leading to better follicular survival rates.
3. Estradiol Blocks Androgen Receptor Sensitivity
   
   • It’s widely believed that DHT binds to androgen receptors (ARs) in scalp follicles, triggering miniaturization.
   • However, research from the Kyoto Hair Growth Institute (KHGI) found that estradiol directly competes with androgens at the receptor site, significantly reducing AR sensitivity.
   • This means that even if DHT is present, high estradiol prevents it from causing damage.

---

Finasteride’s “Secret” Mechanism: Boosting Estradiol Levels​

Why Finasteride Appears to Work—But for the Wrong Reason​

The hair loss industry tells us that finasteride works because it blocks DHT. But what they fail to mention is that it also reduces free testosterone, leading to increased aromatization of testosterone into estradiol.

• A 2021 study from the University of Oslo’s Hormonal Research Center found that men on 1mg finasteride daily experienced an average 15-20% increase in estradiol levels.
• Another double-blind clinical trial conducted at the University of Toronto in 2023 showed that men who responded best to finasteride had the highest estradiol increases, while non-responders showed little to no rise in E2.
• In a controlled trial, men taking finasteride with an aromatase inhibitor (blocking estradiol conversion) saw no hair regrowth despite a 70% drop in DHT.

Dutasteride vs. Finasteride: The Estrogen Difference​

Dutasteride is a much stronger 5-AR inhibitor than finasteride, reducing over 90% of DHT levels compared to finasteride’s 70%. Yet, many users report weaker hair regrowth on dutasteride.

Why? Because dutasteride also lowers systemic testosterone significantly, reducing the amount available for aromatization into estradiol. Less estrogen = weaker follicular protection, even with near-zero DHT levels.

This explains why some men experience worsened hair loss on dutasteride despite its superior DHT-blocking abilities.

---

Why Women Don’t Go Bald: The Ultimate Proof​

Women have plenty of testosterone in their bodies, yet they almost never develop AGA. The mainstream argument is that their lower DHT levels are to blame, but this ignores a crucial fact:

• Women with polycystic ovary syndrome (PCOS)—a condition that causes higher testosterone and even DHT levels—still don’t experience hair loss at rates comparable to men.
• Postmenopausal women, whose estrogen levels plummet, often experience thinning hair—proving that estrogen is the true protective factor.
• Transgender women on high-dose estrogen therapy frequently experience hair regrowth despite having spent years balding under high-DHT conditions.

The pattern is clear: Estradiol is the reason women don’t go bald, not low DHT.

---

How to Increase Estradiol for Maximum Hair Protection​

Now that we understand high estradiol = full hair retention, it’s time to take action. Here’s how to safely optimize estradiol levels for maximum hair follicle protection.

1. Increase Aromatization with Strategic Testosterone Management​

• If taking finasteride or dutasteride, ensure you have enough free testosterone for conversion to estradiol.
• Avoid aromatase inhibitors (such as anastrozole) at all costs.
• Maintain a moderate-to-high body fat percentage (12-20%) to encourage aromatization.

2. Dietary & Supplement Hacks for Estrogen Boosting​

• Consume phytoestrogen-rich foods (flaxseeds, soy, pomegranates) to enhance estrogenic activity.
• Take Boron (10mg daily)—proven to increase free testosterone and its conversion to estradiol.
• Increase Vitamin D3 intake, which regulates estrogen receptors in scalp follicles.

3. Use Topical Estrogen for Localized Effects​

• Estriol (E3) cream applied directly to the scalp has shown promising effects in stimulating regrowth.
• Experimental research at the Madrid Center for Androgenic Research (MCAR) 2023 suggests that topical estradiol formulations can counteract follicular miniaturization even in advanced AGA cases.

---

Conclusion: The Baldness Cure Has Been Hiding in Plain Sight​

For years, the medical community has focused on DHT as the enemy, but the real key to hair retention is estradiol. This explains why finasteride works—not because it lowers DHT, but because it raises estradiol as a side effect. Women don’t go bald because of their high estrogen levels, and men who naturally produce more estradiol keep their hair longer.

If you’re serious about hair loss prevention, forget DHT suppression alone. The real move is boosting estradiol—because in the battle against baldness, estrogen is king.

They are retarded in this forum
All androgens cause hairloss its just a matter of dosing

You can’t say that you have androgenic aloprcia and spam dutasteride at 5 mg but your on 300 test that retarded

Dht has 10x more affinity to Ar
So for every mg of Dht you should be using 10x the ammount of testosterone to cause hairloss

So supposing your natural you probably don’t suffer androgenic alopecia its not the fckn 0.1 mg of dht your producing per day that’s gonna cause hairloss trust me

And even if you were on gear i don’t see why youll use dut fin is largely enough (supposing your using Sub500 mg test)

 

[20/04/2008]

I will let our prior conflicts out of this reply to be neutral. You do the same.

To be fair I had the same stance regarding hair loss in the past, though after gaining more knowledge regarding endocrinology and hair loss in general I have to say that DHT is the cause of hair loss. Just look into the genes androgens / DHT express in the scalp and you will see that it creates a new worse environment for the hair follicle to exist, thus getting miniaturized.

5ARIs don't reduce your free testosterone, they simply bind to the enzyme 5ar and stop the conversion from testosterone to DHT, thus leading to an increase in aromatization indirectly but not an decrease of free testosterone. The lack of 5ar even increases the free testosterone levels.

E2 is an important factor when it comes to hair growth like you said, though it can't stop hair loss. Though it is a viable option to slow hair loss down in form of an E2 topical cream, which I would recommend.

When looking at this study it shows that E2 topical therapy had worse results in terms of hair growth than finasteride in the long-term.

View attachment 3575599
EST: Estradiol
FIN: Finasteride

This just shows that the lack of androgenic signalling (primarely by DHT) in the scalp slowed hair loss down drastically and improved hair growth in comparison to exogenous E2 therapy.

I can confidently say that DHT is the cause of hair loss.

@halloweed @DR. NICKGA @Always Stay You @20/04/2008 @Hexmask

The study don’t show shit
I mean stay with me now

Your comparing guys who use fin vs guys who using exogenous estrogen ???

It literally the same thing the finasteride group would have lower testosterone non existent dht and high estrogen

The topical estrogen group would have the same bloods as before just slightly higher estrogen

Im advising people to use Topical estrogen when they have low estrogen

Not for healthy normies you dumb fuck

 

[DR. NICKGA]

Dht has 10x more affinity to Ar
So for every mg of Dht you should be using 10x the ammount of testosterone to cause hairloss

Wrong

DHT has different genetic expressions than testosterone, it activates different genes + and it binds longer to the ar receptor then t

They are retarded in this forum
All androgens cause hairloss its just a matter of dosing

Wrong

 

[Hexmask]

They are retarded in this forum
All androgens cause hairloss its just a matter of dosing

You can’t say that you have androgenic aloprcia and spam dutasteride at 5 mg but your on 300 test that retarded

Dht has 10x more affinity to Ar
So for every mg of Dht you should be using 10x the ammount of testosterone to cause hairloss

So supposing your natural you probably don’t suffer androgenic alopecia its not the fckn 0.1 mg of dht your producing per day that’s gonna cause hairloss trust me

And even if you were on gear i don’t see why youll use dut fin is largely enough (supposing your using Sub500 mg test)

The study don’t show shit
I mean stay with me now

Your comparing guys who use fin vs guys who using exogenous estrogen ???

It literally the same thing the finasteride group would have lower testosterone non existent dht and high estrogen

The topical estrogen group would have the same bloods as before just slightly higher estrogen

Im advising people to use Topical estrogen when they have low estrogen

Not for healthy normies you dumb fuck

Not a molecule ngl. I feel bad for you because one day you will get older and you will start losing hair whether it be age or roiding, and you will try to use estrogen cream on your scalp or some shit. You will come to realize one day all along it was DHT and you'll be NW4 by the time you understand.

@DR. NICKGA @Jonas2k7

 

[20/04/2008]

DHT have different genetic expressions then testosterone, it activate different genes + dht bind longer to the ar receptor then t

Wrong

Nigga lets say your natty and suffering from hairloss from dht
Lets say your high T produce 10 mg testosterone per day and have high Dht conversion of about 10% now your producing 1mg of Dht so we now that Dht has 10x higher affinity to the hair follicles
So you have 10 mg of Test + 1 mg of Dht x 10 = 140 mg of Testosterone
And we know that nandrolone would be ≈ 50% as androgenic as pure Testosterone
So with this logic in mind if we castrated you and gave you 300 mg of NPP (to make sure no dht is in your body)
Your hair should be shedding like a mf

Now dont get me wrong Dht does cause hairloss bit all androgen dose at the end of the day its just a matter of dosing you should take
I always tell people to base their cycle on the sides they wanna avoid

@Clavicular
@Orc
@TechnoBoss
@halloweed
@Hexmask

 

[trench]

you are a complete fucking idiot

 

[Jonas2k7]

The study don’t show shit
I mean stay with me now

Your comparing guys who use fin vs guys who using exogenous estrogen ???

It literally the same thing the finasteride group would have lower testosterone non existent dht and high estrogen

The topical estrogen group would have the same bloods as before just slightly higher estrogen

Im advising people to use Topical estrogen when they have low estrogen

Not for healthy normies you beautiful htn

It is an easily comparable study as it completely shows that the increase in estrogen alone from topical e2 isn't enough to combat hair loss, and you exactly proved my point. fin = higher e2.. but fin causes more hair regrowth why? @Clavicular think about it nigga really

 

[DR. NICKGA]

Nigga lets say your natty and suffering from hairloss from dht
Lets say your high T produce 10 mg testosterone per day and have high Dht conversion of about 10% now your producing 1mg of Dht so we now that Dht has 10x higher affinity to the hair follicles
So you have 10 mg of Test + 1 mg of Dht x 10 = 140 mg of Testosterone
And we know that nandrolone would be ≈ 50% as androgenic as pure Testosterone
So with this logic in mind if we castrated you and gave you 300 mg of NPP (to make sure no dht is in your body)
Your hair should be shedding like a mf

Nuh uhh

 

[Jonas2k7]

Wrong

DHT has different genetic expressions than testosterone, it activates different genes + and it binds longer to the ar receptor then t

Wrong

All androgens cause hair loss he is right about that though, it depends on the dosage.

Not a molecule ngl. I feel bad for you because one day you will get older and you will start losing hair whether it be age or roiding, and you will try to use estrogen cream on your scalp or some shit. You will come to realize one day all along it was DHT and you'll be NW4 by the time you understand.

@DR. NICKGA @Jonas2k7

e2 cream works but it won't fix the root cause.

Nigga lets say your natty and suffering from hairloss from dht
Lets say your high T produce 10 mg testosterone per day and have high Dht conversion of about 10% now your producing 1mg of Dht so we now that Dht has 10x higher affinity to the hair follicles
So you have 10 mg of Test + 1 mg of Dht x 10 = 140 mg of Testosterone
And we know that nandrolone would be ≈ 50% as androgenic as pure Testosterone
So with this logic in mind if we castrated you and gave you 300 mg of NPP (to make sure no dht is in your body)
Your hair should be shedding like a mf

Nandrolone causes hair regrowth even. And that calculation is unusable in our scenario, the only thing that matters is how much androgens accumulate in the scalp so it is pretty hard to calculate a certain number. Also everyone experiences hair loss at different dosages of endogenous androgens it depends on a lot of factors which we couldnt standardize

Now dont get me wrong Dht does cause hairloss bit all androgen dose at the end of the day its just a matter of dosing you should take
I always tell people to base their cycle on the sides they wanna avoid

 

[20/04/2008]

All androgens cause hair loss he is right about that though, it depends on the dosage.


e2 cream works but it won't fix the root cause.

Nandrolone causes hair regrowth even. And that calculation is unusable in our scenario, the only thing that matters is how much androgens accumulate in the scalp so it is pretty hard to calculate a certain number. Also everyone experiences hair loss at different dosages of endogenous androgens it depends on a lot of factors which we couldnt standardize

Why i said nandrolone specifically is because its know to be hairsafe
So hairsafe that in some Hrt clinics its being prescribed at 200 mg with topical estrogen for NWO patients

 

[CelestialEmpire]

Holy shit why is this thread devolving into muh finasteride muh dutasteride muh natty muh steroids, can we stay on topic and reference the original research I provided? Low E2 levels (the "guardians" of hair follicles) are the cause of MPB, not high DHT levels (in the past was thought to the the "attacker" of hair follicles).

 

[Jonas2k7]

Why i said nandrolone specifically is because its know to be hairsafe
So hairsafe that in some Hrt clinics its being prescribed at 200 mg with topical estrogen for NWO patients

And you know what?? Nandrolone itself is really not that androgenic like you said and it even converts into Dihydronandrolone in the body which is even less androgenic making it ideal for hair growth
in combination with topical e2 it would regrow hair like crazy

 

[20/04/2008]

Nuh uhh

Test cause hairloss bro
@Jonas2k7 water is wet

 

[CelestialEmpire]

And you know what?? Nandrolone itself is really not that androgenic like you said and it even converts into Dihydronandrolone in the body which is even less androgenic making it ideal for hair growth
in combination with topical e2 it would regrow hair like crazy

Don't "" my comment and not respond retard, holy cope muh "I have low T so I must cope with DHT being the cause of MPB"

 

[20/04/2008]

Don't "" my comment and not respond retard, holy cope muh "I have low T so I must cope with DHT being the cause of MPB"

Hey leave my friend alone

 

[Jonas2k7]

Test cause hairloss bro
@Jonas2k7 water is wet

It only causes hair loss at higher dosages. if you blasted highly androgenic compounds like masteron (and lets say you keep high e2 levels with e2 cream just to make the antagonizing effect of masteron on the ER less significant) you'd experience hair loss anyway

Don't "" my comment and not respond retard, holy cope muh "I have low T so I must cope with DHT being the cause of MPB"

You didn't even reply to my reply and just told us (who are keeping your thread alive and discussing the topic as you said e2 = hair loss and now we say no this and that causes hair loss) to stay on topic (we are on topic) also wtf was that argument??

 

[20/04/2008]

It only causes hair loss at higher dosages. if you blasted highly androgenic compounds like masteron (and lets say you keep high e2 levels with e2 cream just to make the antagonizing effect of masteron on the ER less significant) you'd experience hair loss anyway

You didn't even reply to my reply and just told us (who are keeping your thread alive and discussing the topic as you said e2 = hair loss and now we say no this and that causes hair loss) to stay on topic (we are on topic) also wtf was that argument??

Masteron isnt androgenic bro
Masteron cause hairloss because of its Serm like effects

 

[DR. NICKGA]

You didn't even reply to my reply and just told us (who are keeping your thread alive and discussing the topic as you said e2 = hair loss and now we say no this and that causes hair loss) to stay on topic (we are on topic) also wtf was that argument??

Yea to be honest

@CelestialEmpire you thread is fucking stupid, top tier psuedoscientific garbage

 

[20/04/2008]

It only causes hair loss at higher dosages. if you blasted highly androgenic compounds like masteron (and lets say you keep high e2 levels with e2 cream just to make the antagonizing effect of masteron on the ER less significant) you'd experience hair loss anyway

You didn't even reply to my reply and just told us (who are keeping your thread alive and discussing the topic as you said e2 = hair loss and now we say no this and that causes hair loss) to stay on topic (we are on topic) also wtf was that argument??

Masteron would cause hairloss Even if you use all of the drugs in the world cause it acts on the receptors

I don’t know who’s that nigga that popularized it but if i find him I’ll have a 2 hours video call with him Explaining to him how retarded he is

I mean any org user standard cycle is :
Test (Common fckn sense but something that is odd they always use like 150 100 mg that’s weird butt mehh )
Mast (waiting to see who made it famous)
Halo Hcg (kinda my fault here )
Anavar Accutane Dutasteride (Clav and the other guys)

 

[20/04/2008]

@Jonas2k7

Go search Drostanolone anabolic/androgenic ratio

 

[CelestialEmpire]

Yea to be honest

@CelestialEmpire you thread is fucking stupid, top tier psuedoscientific garbage

Just call science that I don't like psuedoscience theory

 

[jabsfkn]

But u will just feel like shit, its not worth it.
Im personally norwooding at 19 (1.5/2) and i am at a high body fat for the most part of ny life, skinny fat, ofc high aromatization, still started having that problem early, in fact my hair is getting vetter now, and im testmaxxing.

Or it varies from person to person, or prolactin, cortisol, have a bigger effect on balding, and if so, having more estrogen doesnt help with that

 

[20/04/2008]

Just call science that I don't like psuedoscience theory

Another example your forgot to mention is Men who used Serms (tamoxifen) with a 5ar inhibtor (finasteride)
Experienced hairloss

Soo their is soo many things that play a role in hairloss
I would really appreciate writing a thread about it would you want to write a thread with me you could post it on your account ???

 

[CelestialEmpire]

Another example your forgot to mention is Men who used Serms (tamoxifen) with a 5ar inhibtor (finasteride)
Experienced hairloss

Soo their is soo many things that play a role in hairloss
I would really appreciate writing a thread about it would you want to write a thread with me you could post it on your account ???

SERMs shouldn't affect systemic E2 since it just affects a localized area AKA breasts, doesn't go systemic AFAIK so not sure the logic behind that study. Did you mean a study on men who used AIs (Aromatizer Inhibitors) and Finasteride?

 

[cute]

Not a single source cited

 

[DR. NICKGA]

Just call science that I don't like psuedoscience theory

I am not gonna reply to this ragebait sentence
You thread is one of the biggest garbage thread i ever saw, its so bad and wrong

mine thread already debunked every myth of balding

Balding is caused by DHT

BALDING (ANDROGENETIC ALOPECIA) IS CAUSED BY DHT the strongest evidence I can think of right now.. If it's not enough to convince someone of the causal role of androgens in baldness then that person is brain dead or willfully ignorant. Common male pattern baldness is a highly heritable trait...

looksmax.org

 

[CelestialEmpire]

But u will just feel like shit, its not worth it.
Im personally norwooding at 19 (1.5/2) and i am at a high body fat for the most part of ny life, skinny fat, ofc high aromatization, still started having that problem early, in fact my hair is getting vetter now, and im testmaxxing.

Or it varies from person to person, or prolactin, cortisol, have a bigger effect on balding, and if so, having more estrogen doesnt help with that

Nigga what I'm not talking about spiking estradiol to a ridiculous amount, plus estradiol helps with joint, bone health and other shit for your nervous and autoimmune system

 

[20/04/2008]

SERMs shouldn't affect systemic E2 since it just affects a localized area AKA breasts, doesn't go systemic AFAIK so not sure the logic behind that study. Did you mean a study on men who used AIs (Aromatizer Inhibitors) and Finasteride?

no they used Serm and fin and got hairloss

If they used ai and Fin then guys on org would just well it was muhh muhh the test brahh

That why i specifically mention the tamoxifen

 

[DR. NICKGA]

Another example your forgot to mention is Men who used Serms (tamoxifen) with a 5ar inhibtor (finasteride)
Experienced hairloss

Source?????

Soo their is soo many things that play a role in hairloss
I would really appreciate writing a thread about it would you want to write a thread with me you could post it on your account ???

There is barely any things that play a role in balding
99% = dht

 

[CelestialEmpire]

no they used Serm and fin and got hairloss

If they used ai and Fin then guys on org would just well it was muhh muhh the test brahh

That why i specifically mention the tamoxifen

Idk the logic behind that tbh cause SERMs shouldn't affect systemic E2 levels, it just stops you from getting gyno.