Guys, this is driving me absolutely crazy and no one can give a straight answer *HIGH IQ GTFIH*

[DR. NICKGA]

finasteride inhibits type 2 5-alpha-reductase reduces DHT production mainly in tissues like the scalp and prostate, facial bones are likely fused at 17 so no it doesn't affect it, Bone expresses type 1 5-alpha-reductase Finasteride’s weak effect on type 1 means DHT production in bone is hugely preserved, your growth plates have likely fused but clavicle bones end growth at 25 same with spine so it might effect your shoulder width, still bone relies on type 1 5-alpha-reductase not finasterides target but still affects it a little bit. your take on dht supporters is so overestimated it's funny, bone relies more on testosterone for masculinity than DHT it's still up to you in using it or not.

Thats what i said

 

[poloralf]

Does DHT have any notable influence on bone mass/forward growth/facial structure, or is that testosterone's job?

My hairline started receding at 16, and Im now on finasteride at 17 to combat it. Im at norwood 2 right now, and have a strong family history of balding. My question is, will blocking type 2 5-alpha-reductase have a negative effect on the growth and masculinization of my facial bones specifically? Also my frame and growth plates.

DHT haters say: DHT is a paracrine and intracrine hormone that works in the male reproductive and integumentary system to act on the prostate, skin, and genitalia. Testosterone, not DHT, is the androgen that affects bones.

DHT supporters say: In addition to that, DHT also works as an androgen within the skeletal system to affect bone growth in a way that other hormones (testosterone, IGF1) cannot. Blocking 5 alpha reductase 2 will result in less bone growth and development than allowing the enzyme to interact with testosterone.

I want to know which of these stances is more physiologically correct. Please no tiktok knowledge, I want actual answers instead of slideshow knowledge. I know DHT has 5x more affinity for the androgen receptor than testosterone, but does it work on androgen receptors in a similar way to testosterone all throughout the body, or does it work on androgen receptors in a more specialized and isolated way differently than testosterone?

it does, but the mainstream cope is that "it doesnt" you'll turn into a eunuch that cant get it up with immobile liquid sperm, your behavior will become cucked too.
Use ru58841 topically mixed with minoxidil, it doesnt lower dht but competes and binds to follicles in a stronger way than dht in your scalp and stops the balding from happening.

 

[m0ss26]

@m0ss26 help this tard

My hairline started receding at 16, and Im now on finasteride at 17 to combat it. Im at norwood 2 right now, and have a strong family history of balding. My question is, will blocking type 2 5-alpha-reductase have a negative effect on the growth and masculinization of my facial bones specifically? Also my frame and growth plates.

DHT has no affect on frame, keep taking fin ur not missing shit

 

[Lawton88]

If you are balding at 16 no power on this earth will save you from the Norwood Reaper. Don't nuke DHT and develop the most you can and use a hair system.

 

[HandsomeOrDeath]

Thats what Im doing, I just need to know that Im not fucking myself out of facial gains

I have researched this topic thoroughly in years past. The answer is: Only DHT type 1 is involved with bone formation. Type 2 is involved with penis growth and body/face hair development. Finasteride only lowers type 2 dht and leaves type 1 unaffected. Dutasteride lowers both types of Dht. Don't take dutasteride until 23ish. Finasteride is safe once puberty ends 16/17ish.

 

[AverageCurryEnjoyer]

Ru55841 topical or topical shit for hairline and that solves the issue. Take some var or oral dht to get it back and run a test base. Pretty much solved.