Hair loss drug PP405 is a FAILED SCAM: Incoming financial IMPLOSION of Pelage Pharmaceuticals

[Prøphet]

Last month the WHO listed the developing hair loss treatment PP405 under the name “suvomipic”

While classifying the molecule, they revealed that it is the same as JXL069. PP405 is JXL069. Pelage Pharma lied to the public when they earlier stated that PP405 is a different molecule.

JXL069 has been sold on the grey market for a long time now. And the consensus across several different sources and users is that it does not work at all.

Pelage is in absolute shambles and will be utterly evaporated within a year. Needless to say, anti-dut norwood victims are currently on suicide watch reading this. It seems like the last hope of any new treatments this decade has been shattered. Now it makes complete sense why Pelage has refused to release any raw data from their Phase 2 trials, instead sharing only vague and manipulated percentages. This is so brutal honestly I had a lump in my throat when I found out. We can now officially add PP405 to the list of failed drugs, beaten by the Norwood Reaper.

*The 16 year old Norwood 3 survivor reading this post*

 

[Prøphet]

@combatingNorwooding Did you hear about this

 

[sonic55555]

Hm. Im not interested in a hair loss drug tho. I want a hair regrowth drug

 

[Prøphet]

Hm. Im not interested in a hair loss drug tho. I want a hair regrowth drug

This was meant for hair regrowth. Supposedly it regrew 30% of hair in 20% of clinical trial patients. But now we know through real world data that this statistic is manipulated and probably just normal hair cycles.

 

[sonic55555]

This was meant for hair regrowth. Supposedly it regrew 30% of hair in 20% of clinical trial patients. But now we know through real world data that this statistic is manipulated and probably just normal hair cycles.

Well dang

 

[Prøphet]

Well dang

The company has hundreds of millions of dollars invested in it by Google. They’re going to be so pissed lol.

 

[sonic55555]

The company has hundreds of millions of dollars invested in it by Google. They’re going to be so pissed lol.

im convinced that 99% of science is a giant hoax. Look at everything around you, have computers gotten alot better since 10 years ago? No. Even cars have barely gotten better and it took a supergenius to make electric cars a thing

Science is so useless. Where's the cure for cancer? How hard can it be to cure fking cancer when you have a million scientists of the supposedly highest iq people the world working 24/7 to find a cure, yet nothing.

I have zero hope in a hair loss drug being invented. I think a hair system is the way to go

 

[CheezyPoof]

If there is already fin min and dut (+ the RU drug with the numbers) why would they need a new drug for this?

They should develop a drug that will prevent pubes and armpit hair so people don’t have to shave anymore that would be a good investment

 

[nocajebudala]

anything but fin lol ofc no peptide is going to regrow nw5

 

[sonic55555]

If there is already fin min and dut (+ the RU drug with the numbers) why would they need a new drug for this?

They should develop a drug that will prevent pubes and armpit hair so people don’t have to shave anymore that would be a good investment

twink fag poster

 

[Prøphet]

im convinced that 99% of science is a giant hoax. Look at everything around you, have computers gotten alot better since 10 years ago? No. Even cars have barely gotten better and it took a supergenius to make electric cars a thing

Science is so useless. Where's the cure for cancer? How hard can it be to cure fking cancer when you have a million scientists of the supposedly highest iq people the world working 24/7 to find a cure, yet nothing.

I have zero hope in a hair loss drug being invented. I think a hair system is the way to go

Well I think computers have gotten better but that’s about it. We’re certainly in a plateau compared to the post war-information age period, 1940s to I would say 2000s. Maybe there’s some economic reason things have stagnated so badly. Honestly the only hope left is breezula, but even that is looking like a scam as well due to the company’s refusal to share the data. Not to mention years of anecdotal evidence that clascoterone is too weak. So we’re back to waiting for some new mechanism, which once discovered is going to take 5 years to come to market. So basically everything’s fucked.

 

[Prøphet]

anything but fin lol ofc no peptide is going to regrow nw5

It wasn’t a peptide, it used a totally novel mechanism of action to push hairs into anagen

 

[sonic55555]

Well I think computers have gotten better but that’s about it. We’re certainly in a plateau compared to the post war-information age period, 1940s to I would say 2000s. Maybe there’s some economic reason things have stagnated so badly. Honestly the only hope left is breezula, but even that is looking like a scam as well due to the company’s refusal to share the data. Not to mention years of anecdotal evidence that clascoterone is too weak. So we’re back to waiting for some new mechanism, which once discovered is going to take 5 years to come to market. So basically everything’s fucked.

 

[nocajebudala]

It wasn’t a peptide, it used a totally novel mechanism of action to push hairs into anagen

besides that, shits now useless

 

[Prøphet]

If there is already fin min and dut (+ the RU drug with the numbers) why would they need a new drug for this?

They should develop a drug that will prevent pubes and armpit hair so people don’t have to shave anymore that would be a good investment

I would estimate 5% of people can’t tolerate 5ar inhibitors

And lets say, for another 10% of people, 5ar inhibitors aren’t strong enough

If you look at how common male pattern baldness is, and how increasingly necessary it is for men to preserve their hair, it financially makes sense to develop new treatments that can be stacked or used in substitute for others

 

[Prøphet]

@norwoodingmanlet

 

[Bipolar2Cel]

If there is already fin min and dut (+ the RU drug with the numbers) why would they need a new drug for this?

They should develop a drug that will prevent pubes and armpit hair so people don’t have to shave anymore that would be a good investment

RU is a garbage cope drug too, from what I saw quoted it has WORSE binding affinity to AR than both T and DHT does, no wonder most guys seem to fail with it let alone use it on roid stacks with fin/dut + minoxidil + RU and go bald anyway, probably it competes at AR even worse vs systemic synthetic super potent androgens lmfao.. it is mostly a cope drug that many don't even know how it should be used when using it anyway and just guessing, plus topical absorption is poor compared to systemic androgen deliveries directly to hair follicles lol.

Fin/dut + minoxidil are still the golden standards of MPB treatment most anything else are copes or seem to be useless even lol. Obviously if you value your hair you shouldn't even be doing roids or at worst only stick to T + dutasteride + minoxidil and hope those superphysiological levels of T don't slowly miniaturize your hair follicles anyway.

 

[Prøphet]

RU is a garbage cope drug too, from what I saw quoted it has WORSE binding affinity to AR than both T and DHT does, no wonder most guys seem to fail with it let alone use it on roid stacks with fin/dut + minoxidil + RU and go bald anyway, probably it competes at AR even worse vs systemic synthetic super potent androgens lmfao.. it is mostly a cope drug that many don't even know how it should be used when using it anyway and just guessing, plus topical absorption is poor compared to systemic androgen deliveries directly to hair follicles lol.

Fin/dut + minoxidil are still the golden standards of MPB treatment most anything else are copes or seem to be useless even lol. Obviously if you value your hair you shouldn't even be doing roids or at worst only stick to T + dutasteride + minoxidil and hope those superphysiological levels of T don't slowly miniaturize your hair follicles anyway.

I mean binding affinity isn’t everything. Look at pyrilutamide, iirc it’s binding affinity is much higher than endogenous androgens, yet it doesn’t perform any better than placebo, while RU outperformed even finasteride in macaque monkeys. Appparently there could be other factors like sheer volume of the molecules for example.

RU has decades of anecdotal evidence that it works at least more than placebo. The more worrying thing about it is the unknown cardiac effects.

 

[Bipolar2Cel]

I mean binding affinity isn’t everything. Look at pyrilutamide, iirc it’s binding affinity is much higher than endogenous androgens, yet it doesn’t perform any better than placebo, while RU outperformed even finasteride in macaque monkeys. Appparently there could be other factors like sheer volume of the molecules for example.

RU has decades of anecdotal evidence that it works at least more than placebo. The more worrying thing about it is the unknown cardiac effects.

Better to use what is known to work than cope.

 

[Richard Cheese]

still coping about hair loss in big 2026.

MUH hair cloning. MUH vertoporfin. MUH whatever the fuck. any 5 more years now.
Instead of coping how about you JUST TAKE FIN OR DUT like we've done for 30 YEARS.

 

[Bipolar2Cel]

still coping about hair loss in big 2026.

MUH hair cloning. MUH vertoporfin. MUH whatever the fuck. any 5 more years now.
Instead of coping how about you JUST TAKE FIN OR DUT like we've done for 30 YEARS.

Plus minoxidil, just helps keeping hair follicle even more healthy and boosted and keeping more hair follicles actively growing always. Prolongs anagen phase and ability to grow length AND literally fucking boosts hair shaft diameter. Makes miniaturized and intermediate hairs longer and thicker too which provides even more visual density and thickness lol. Feels like such a no-brainer addition to fin/dut to me.

 

[choppedpajeet]

straight from haircafe butanyways all these anti fin/dut will start using all this shit as soon as they hit NW3 OR 4 its a cannon event

 

[combatingNorwooding]

@combatingNorwooding Did you hear about this

Yes. Haircafe already debunked this. PP is cope