Halotestin
17aa oral / fluoxymesterone
THIS IS GENERAL INFO, RESEARCH MORE IN DEPTH BY YOURSELF I DO NOT TAKE ANY RESPONSABILITIES IF YOU FUCK YOURSELF UP
17aa oral / fluoxymesterone
THIS IS GENERAL INFO, RESEARCH MORE IN DEPTH BY YOURSELF I DO NOT TAKE ANY RESPONSABILITIES IF YOU FUCK YOURSELF UP
there are no modern trials and nothing recent about it,
dont fuck with 17aa orals if you dont know what youre doing for the love of god, its not the same as "oh ill just run test im just low inhib and chad", i see many retards running tren + halo as their first exogenous compounds. your liver is still adapting LIPID PROFILE LIVES MATTER
Halotestin is fluoxymesterone. It is one of the most androgenic orals ever synthesized in history. It gives you strength and aggression out of proportion to muscle gain. It also rapes your liver, crushes your lipids and mainly shuts you down
dont fuck with 17aa orals if you dont know what youre doing for the love of god, its not the same as "oh ill just run test im just low inhib and chad", i see many retards running tren + halo as their first exogenous compounds. your liver is still adapting LIPID PROFILE LIVES MATTER
Halotestin is fluoxymesterone. It is one of the most androgenic orals ever synthesized in history. It gives you strength and aggression out of proportion to muscle gain. It also rapes your liver, crushes your lipids and mainly shuts you down
its full name is 17 alpha alkylated oral androgen. The 17aa modification lets it survive first pass of liver metabolism, which is why it works orally but also why it messes your liver up. It was developed in the 1950s for hypogonadism, delayed puberty, and breast cancer in women. Medical use has declined to nearly zero because better options exist and have developed.
It binds the androgen receptor with high affinity.
No aromatization
No water weight
No gyno
The weird part, is the strength gains exceed the muscle gains, which means you lift more without necessarily looking bigger
It binds the androgen receptor with high affinity.
No aromatization
No water weight
No gyno
The weird part, is the strength gains exceed the muscle gains, which means you lift more without necessarily looking bigger
Enters cell through membrane diffusion, binds cytosolic androgen receptor, the complex undergoes conformational change, shifts to nucleus, binds androgen response elements on DNA.
Upregulates myosin heavy chain expression, igf1 signaling components, erythropoietin pathways. Downregulates catabolic machinery possibly via glucocorticoid antagonism, though this is less certain and not supported well by studies.
Primary effect is AR activation
Secondary is CNS stimulation, it likely involves dopamine and serotonin modulation, not fully characterized, possibly indirect through androgen receptor presence in neural tissue.
Tertiary is the anti glucocorticoid effect. so it may reduce muscle breakdown during stress.
The strength without size comes from increased motor neuron excitability. Your nervous system fires motor units harder and more synchronously. Your muscles do not grow much, they just contract harder, meaning you should stack it with something else.
Upregulates myosin heavy chain expression, igf1 signaling components, erythropoietin pathways. Downregulates catabolic machinery possibly via glucocorticoid antagonism, though this is less certain and not supported well by studies.
Primary effect is AR activation
Secondary is CNS stimulation, it likely involves dopamine and serotonin modulation, not fully characterized, possibly indirect through androgen receptor presence in neural tissue.
Tertiary is the anti glucocorticoid effect. so it may reduce muscle breakdown during stress.
The strength without size comes from increased motor neuron excitability. Your nervous system fires motor units harder and more synchronously. Your muscles do not grow much, they just contract harder, meaning you should stack it with something else.
Muscle sees increased contractile protein synthesis, but hypertrophy is limited compared to testosterone or nandrolone. You get stronger without getting much bigger. Powerlifters use this for peaking
Nervous system gets
increased drive, aggression, focus, motor control. some users on other forums report back near immediate effects within days.
On the blood : increased red blood cell production, higher hematocrit, thicker blood. This aids oxygen delivery but raises clot risk, especially if you are already dehydrated or have other risk factors.
on the liver : oxidative stress, cholestasis, bile salt export pump disruption from the 17aa structure. Enzymes rise, bilirubin may rise, jaundice can occur. This is dose and duration dependent, this said for almost everything but the margin is narrow
on the Endocrine : complete hypothalamic pituitary gonadal axis shutdown. GnRH pulse frequency drops, LH and FSH collapse, test shutdown.
Nervous system gets
increased drive, aggression, focus, motor control. some users on other forums report back near immediate effects within days.
On the blood : increased red blood cell production, higher hematocrit, thicker blood. This aids oxygen delivery but raises clot risk, especially if you are already dehydrated or have other risk factors.
on the liver : oxidative stress, cholestasis, bile salt export pump disruption from the 17aa structure. Enzymes rise, bilirubin may rise, jaundice can occur. This is dose and duration dependent, this said for almost everything but the margin is narrow
on the Endocrine : complete hypothalamic pituitary gonadal axis shutdown. GnRH pulse frequency drops, LH and FSH collapse, test shutdown.
Oral bioavailability is high due to 17aa structure. Half life roughly 6 to 9 hours, some sources say up to 12. Split dosing twice daily since it helps maintain levels, though many users take it once pre workout for the CNS effect.
Clinical range was 2 to 20 mg daily. Lower end for replacement, higher end for cancer palliation. sources pushes 30 to 40 mg.
For a 90 kg male the clinical range is 0.02 to 0.22 mg per kg.
If you attempted to scale from rat data like a chad at 1 mg per kg, human equivalent dose would be roughly 0.16 mg per kg using standard allometric conversion.
use is often 10 to 20 mg daily for 2 to 4 weeks before competition, not for entire training cycles, like DNP (is mostly) to shed a few KGs off before competition
Clinical range was 2 to 20 mg daily. Lower end for replacement, higher end for cancer palliation. sources pushes 30 to 40 mg.
For a 90 kg male the clinical range is 0.02 to 0.22 mg per kg.
If you attempted to scale from rat data like a chad at 1 mg per kg, human equivalent dose would be roughly 0.16 mg per kg using standard allometric conversion.
use is often 10 to 20 mg daily for 2 to 4 weeks before competition, not for entire training cycles, like DNP (is mostly) to shed a few KGs off before competition
17 alpha alkylated steroids are the worst category for liver stress. Halotestin is among the most toxic within that category, possibly second only to methyltrienolone.
Serious issues
cholestatic jaundice
elevated transaminases
peliosis hepatis hepatic adenomas
The liver stress can be severe enough to require hospitalization or cause permanent damage
Dyslipidemia is severe
HDL cholesterol drops 30 -50% within weeks
LDL rises
Apolipoprotein wrosen
Cardiovascular risk accumulates easily
Polycycythemia develops reliably
Hematocrit rises
blood viscosity increases
clot risk rises
Jfl you can donate blood to combat this
Serious issues
cholestatic jaundice
elevated transaminases
peliosis hepatis hepatic adenomas
The liver stress can be severe enough to require hospitalization or cause permanent damage
Dyslipidemia is severe
HDL cholesterol drops 30 -50% within weeks
LDL rises
Apolipoprotein wrosen
Cardiovascular risk accumulates easily
Polycycythemia develops reliably
Hematocrit rises
blood viscosity increases
clot risk rises
Jfl you can donate blood to combat this
CYP3A4 inhibitors such as ketoconazole, itraconazole, and some macrolide antibiotics raise fluoxymesterone levels and extend half life. This increases toxicity risk.
Additive liver stress with alcohol, acetaminophen, and other hepatotoxins. The combination of halotestin and heavy drinking is a reliable path to jaundice.
Additive liver stress with alcohol, acetaminophen, and other hepatotoxins. The combination of halotestin and heavy drinking is a reliable path to jaundice.
If you use it anyway despite this information, keep cycles short, two to four weeks maximum. Monitor liver enzymes and lipids before, during, and after. Have GOOD pct. Do not drink alcohol during use or for weeks after. Do not combine with other oral steroids. Stay hydrated to manage hematocrit. Consider blood donation if hematocrit rises above 52 percent. Stop immediately if you develop yellowing of skin or eyes, severe fatigue, or right upper quadrant pain.
