hard caps vs gel caps dutasteride bioavailability difference

[avgsub5human]

sup brahs, I have both avodart pills 0.5mg that are obv gel caps however its expensive like a motherfucker so I got my hands on hard cap ones that quite literally is 10x cheaper, im aware that hard caps have slight less bioavailability and some say to take either mct oil or eat a fatty meal beforehand but I usually take my pills in the morning fasted, would for example taking 2x 0.5mg hard caps (1mg) be around the same effective dose as 0.5mg gel caps even if im fasted? or should I go for something like 1.5mg-2.5mg (I know 2.5mg mogs anything to oblivion but im moreso asking about the bioavailability)

if any of you know how big the difference actually please lmk so I dont underdose it

 

[PepsAreNatty]

Idk but just find your med cap with one of your hb and then just lower that until you stop overdosing

 

[ICL]

this source is cheap
pctzone.is

 

[avgsub5human]

this source is cheap
pctzone.is

pct only has hardcaps last time I checked

 

[ICL]

pct only has hardcaps last time I checked

Last time you checked


I've sourced a new one
https://pctzone.net/warehouse/india/dutasteride-100mg/

 

[avgsub5human]

Last time you checked


I've sourced a new one
https://pctzone.net/warehouse/india/dutasteride-100mg/

mirin thx brah but sadly I doubt india shit will get thru EU customs unless they warehouse it here

 

[ICL]

mirin thx brah but sadly I doubt india shit will get thru EU customs unless they warehouse it here

....

dude


you were supposed to click the link

It was a redirect to pornhub

 

[starborn3995]

this source is cheap
pctzone.is

thats a scam site.......

 

[ICL]

thats a scam site.......

It was actually a redirect to pornhub

 

[AlexRz]

sup brahs, I have both avodart pills 0.5mg that are obv gel caps however its expensive like a motherfucker so I got my hands on hard cap ones that quite literally is 10x cheaper, im aware that hard caps have slight less bioavailability and some say to take either mct oil or eat a fatty meal beforehand but I usually take my pills in the morning fasted, would for example taking 2x 0.5mg hard caps (1mg) be around the same effective dose as 0.5mg gel caps even if im fasted? or should I go for something like 1.5mg-2.5mg (I know 2.5mg mogs anything to oblivion but im moreso asking about the bioavailability)

if any of you know how big the difference actually please lmk so I dont underdose it

Did you figure this out?

 

[avgsub5human]

Did you figure this out?

for the most part no, not via the forum at least

for the most part hardcaps are still quite effective from around ~80% compared to gel caps, so if you wanna round it down alot you could say 50% and just take 1mg hardcaps if ur goal is to equal 0.5mg gelcap for example. Besides, more dut the better

if ur going for 2.5mg I would probably take 3mg since if each pill is about 80% of the 0.5mg you gotta take abit more if you get what im saying.

if you just wanna try to make them more bioavailable eat them with a fat meal, or have it with mct oil (which is kinda cope but whatever works)

you should also check the batch for verification and cerificate if you get it from example indiamart, idk about wwb etc

 

[AlexRz]

for the most part no, not via the forum at least

for the most part hardcaps are still quite effective from around ~80% compared to gel caps, so if you wanna round it down alot you could say 50% and just take 1mg hardcaps if ur goal is to equal 0.5mg gelcap for example. Besides, more dut the better

if ur going for 2.5mg I would probably take 3mg since if each pill is about 80% of the 0.5mg you gotta take abit more if you get what im saying.

if you just wanna try to make them more bioavailable eat them with a fat meal, or have it with mct oil (which is kinda cope but whatever works)

you should also check the batch for verification and cerificate if you get it from example indiamart, idk about wwb etc

Why do you say MCT oil is cope does it not actually work? That’s what I was thinking on using but I can’t find how effective it truly is.

Although higher dut dosages mog, I’m interested in trying 0.1mg/ml daily since it was proven to be as effective as 1mg fin daily. Bioavailability would be a bigger concern for me however since the dose is smaller. Perhaps it doesn’t matter with it’s long half life but I still wanted to make sure

 

[avgsub5human]

Why do you say MCT oil is cope does it not actually work? That’s what I was thinking on using but I can’t find how effective it truly is.

Although higher dut dosages mog, I’m interested in trying 0.1mg/ml daily since it was proven to be as effective as 1mg fin daily. Bioavailability would be a bigger concern for me however since the dose is smaller. Perhaps it doesn’t matter with it’s long half life but I still wanted to make sure

nah it does work, but I meant gel caps are more convient and you can trust it more over eating a fat meal or mct oil, but its better to do either of those two things over not doing them so

powder solution with oil is supposed to be very effective aswell so I wouldnt be concerned if thats what ur running, why lowdose it at 0.1mg though? do uve sides on fin?

 

[AlexRz]

nah it does work, but I meant gel caps are more convient and you can trust it more over eating a fat meal or mct oil, but its better to do either of those two things over not doing them so

powder solution with oil is supposed to be very effective aswell so I wouldnt be concerned if thats what ur running, why lowdose it at 0.1mg though? do uve sides on fin?

Yeah I guess I was mostly worried about it’s effectiveness due to my low dose. If it only has a 50% bioavailability for example in my MCT oil then that’s 0.05mg which is probably too low to be effective. Hopefully it’s close to 0.1mg though and the long half life will compensate. I’ve heard that even with 0 oils (hard caps) it’s still 80% the bioavailability of gel caps. Not sure how accurate that is though.

I use topical fin + min and it doesn’t seem really effective and Im unsure if I have mild sides from it. The reason I don’t go with oral fin is because I was a retard with substances when I was younger and got sides so I want to avoid affecting my brain further. From the theories I’ve developed dut should barely cross the blood brain barrier, and if it does cross, the amount that would get in the brain from 0.1mg daily would have such a negligible effect on it that your brain chemistry wouldn’t even be altered and you couldn’t get brain sides. However fin does cross the BBB very well which is why I think some people get sides on fin but not on dut.

 

[avgsub5human]

Yeah I guess I was mostly worried about it’s effectiveness due to my low dose. If it only has a 50% bioavailability for example in my MCT oil then that’s 0.05mg which is probably too low to be effective. Hopefully it’s close to 0.1mg though and the long half life will compensate. I’ve heard that even with 0 oils (hard caps) it’s still 80% the bioavailability of gel caps. Not sure how accurate that is though.

I use topical fin + min and it doesn’t seem really effective and Im unsure if I have mild sides from it. The reason I don’t go with oral fin is because I was a retard with substances when I was younger and got sides so I want to avoid affecting my brain further. From the theories I’ve developed dut should barely cross the blood brain barrier, and if it does cross, the amount that would get in the brain from 0.1mg daily would have such a negligible effect on it that your brain chemistry wouldn’t even be altered and you couldn’t get brain sides. However fin does cross the BBB very well which is why I think some people get sides on fin but not on dut.

watch this;


topical fin almost always goes systemic, same for topical dut but the sides are not as bad as you think, obv some do get erectile dysfunction but that in itself is rare. But I do understand where ur coming from medications are not to fuck around with, and if ur already "fragile" mentally or how you wanna call it makes it kinda easier for you to develop nocebo effects.

before you go on oral dut id honestly just begin with fin, since if you do get sides on a 5ar blocker getting it on fin would mean they should be gone fast, whereas on dut it will last longer since the halflife is so long but if ur only concerne is BBB then you could try out dut, just be aware that if you do get sides (which you prob wont) it will be there for a tiny bit longer.

and don't read r/tressless or some bullshit stories about post finasteride syndrome its all bullshit, watch more of haircafes videos if youre interested he goes into detail of it more with sources

 

[AlexRz]

watch this;


topical fin almost always goes systemic, same for topical dut but the sides are not as bad as you think, obv some do get erectile dysfunction but that in itself is rare. But I do understand where ur coming from medications are not to fuck around with, and if ur already "fragile" mentally or how you wanna call it makes it kinda easier for you to develop nocebo effects.

before you go on oral dut id honestly just begin with fin, since if you do get sides on a 5ar blocker getting it on fin would mean they should be gone fast, whereas on dut it will last longer since the halflife is so long but if ur only concerne is BBB then you could try out dut, just be aware that if you do get sides (which you prob wont) it will be there for a tiny bit longer.

and don't read r/tressless or some bullshit stories about post finasteride syndrome its all bullshit, watch more of haircafes videos if youre interested he goes into detail of it more with sources

Yeah I watched that video and it matches well with the research I made prior to the video being released. When comparing other molecules that are similar to dutasteride it seems like it barely crosses the BBB or if it does then it’s not in a significant matter.

I’m not too worried about sexual sides effects, I’d just rather it not affect my brain. Another interesting thing is that DHT is mostly made locally, so perhaps DHT levels in the brain will also be unaffected. Sexual side effects can be because of hormones in the brain so that’s also reassuring.