has anybody used fgfr3 inhibitors/cnp analogs

[diddybluddenJOI]

title, did it work and how was the experience

 

[ccwb]

title, did it work and how was the experience

Yeah bro we not rich like that

 

[adamcell]

title, did it work and how was the experience

yep i did

 

[BeatleJuiceFanBoy10]

Does it actually work cuz i heard it doesnt work for ppl that genetically have too much of those receptors (achondroplasia).

 

[exsttttt]

Does it actually work cuz i heard it doesnt work for ppl that genetically have too much of those receptors (achondroplasia).

works better for them + u do NOT have achondroplasia, if u did ud be dwarf

 

[BeatleJuiceFanBoy10]

works better for them + u do NOT have achondroplasia, if u did ud be dwarf

Where did i ever suggest i have achondroplasia. I just said for these people that a FGFR3 inhibitor doesnt work, by extent it also shouldnt work for us is what I was suggesting.

 

[exsttttt]

Where did i ever suggest i have achondroplasia. I just said for these people that a FGFR3 inhibitor doesnt work, by extent it also shouldnt work for us is what I was suggesting.

no, it works better for them and worse for normal humans

 

[diddybluddenJOI]

yep i did

how was fhe experience did it work and were there any side effects

 

[adamcell]

how was fhe experience did it work and were there any side effects

dm me

 

[BeatleJuiceFanBoy10]

no, it works better for them and worse for normal humans

Where is your evidence backing up this claim? Never heard it work personally.

 

[exsttttt]

Where is your evidence backing up this claim? Never heard it work personally.

dont keep askin questions and when they are answered you ask for evidence, if u think im bluffin do ur own research and stop makin people answer your questions AND provide evidence

 

[antifoid111]

Using CNP or vosoritide takes years to show results using HGH + Aromasin is much better.

 

[BeatleJuiceFanBoy10]

dont keep askin questions and when they are answered you ask for evidence, if u think im bluffin do ur own research and stop makin people answer your questions AND provide evidence

Why are you so hostile lol, I litterly just searched for the research on this and found no real complete evidence showing it works for treating achondroplasia let alone normal ppl. Thats why I asked for yours. Making ridiculous statements isnt an answer either.

 

[exsttttt]

Why are you so hostile lol, I litterly just searched for the research on this and found no real complete evidence showing it works for treating achondroplasia let alone normal ppl. Thats why I asked for yours. Making ridiculous statements isnt an answer either.

lol? alright then im wrong if u say so, but i aint wrong, ur just retarded and didnt search hard enough.

 

[BeatleJuiceFanBoy10]

lol? alright then im wrong if u say so, but i aint wrong, ur just retarded and didnt search hard enough.

Buddy you are wrong except if you are a mice, which checks out with the way you reply. And even on mice it hardly treats the symptoms of achondroplasia.

 

[exsttttt]

Buddy you are wrong except if you are a mice, which checks out with the way you reply. And even on mice it hardly treats the symptoms of achondroplasia.

if you had it in you to do the research deeply on ur own, why are you asking ? u clearly know what ur talkin abt

 

[BeatleJuiceFanBoy10]

if you had it in you to do the research deeply on ur own, why are you asking ? u clearly know what ur talkin abt

That is because in the first year of the bachelors this was a large part of my curriculum. We studied there that FGFR3 has no medicine and FGFR3 currently did not work on mice. However that was last year, so maybe I thought you found new studies showing that it worked. WHICH is why I asked if you had new evidence proving it actually does work. I can also see you did your research about this on your (free) time which is commendable but statements require proof that works on humans, tall guy.

 

[exsttttt]

That is because in the first year of the bachelors this was a large part of my curriculum. We studied there that FGFR3 has no medicine and FGFR3 currently did not work on mice. However that was last year, so maybe I thought you found new studies showing that it worked. WHICH is why I asked if you had new evidence proving it actually does work. I can also see you did your research about this on your (free) time which is commendable but statements require proof that works on humans, tall guy.

fgfr3 has no medicine? hmm i wonder why cnp analogs for achondroplasia exist and work, i wonder why infigratinib is used in pediatric treatment and rescue

 

[BeatleJuiceFanBoy10]

fgfr3 has no medicine? hmm i wonder why cnp analogs for achondroplasia exist and work, i wonder why infigratinib is used in pediatric treatment and rescue

I meant achondroplasia has no medicine but you prob get the point and im stating this for my country and the current state of medicine for it. As of 2026, there is no treatment for achondroplasia and FGFR antagonist while promising are not yet giving for achondroplasia in atleast my country. Far less for a potential height gain for normal ppl.

 

[adamcell]

Using CNP or vosoritide takes years to show results using HGH + Aromasin is much better.

LOL

 

[exsttttt]

I meant achondroplasia has no medicine but you prob get the point and im stating this for my country and the current state of medicine for it. As of 2026, there is no treatment for achondroplasia and FGFR antagonist while promising are not yet giving for achondroplasia in atleast my country. Far less for a potential height gain for normal ppl.

your country doesnt mean the whole word, there are countless studies on infigratinib given for off label achondroplasia showing effectiveness at low doses.

 

[antifoid111]

LOL

????

 

[BeatleJuiceFanBoy10]

your country doesnt mean the whole word, there are countless studies on infigratinib given for off label achondroplasia showing effectiveness at low doses.

Yes but there are different stages of a study, there could be countless confounders why it works early on. There is a reason not everyone out there gets this and still it still hasnt shown anything for regular ppl.

 

[exsttttt]

Yes but there are different stages of a study, there could be countless confounders why it works early on. There is a reason not everyone out there gets this and still it still hasnt shown anything for regular ppl.

erda did for regular people, same w tyra, although tyra is pretty expensive, but both demonstrate proof of concept

 

[BeatleJuiceFanBoy10]

erda did for regular people, same w tyra, although tyra is pretty expensive, but both demonstrate proof of concept

yes but correlation doesnt mean causation. And while it does sound righ, it could not work for regular ppl. Just like HGH doesnt work for ppl who arent deficient. (See alot of ppl believing it does, if it did government would give it to everyone, they'd make alot of profit that way).

 

[exsttttt]

yes but correlation doesnt mean causation. And while it does sound righ, it could not work for regular ppl. Just like HGH doesnt work for ppl who arent deficient. (See alot of ppl believing it does, if it did government would give it to everyone, they'd make alot of profit that way).

you are an absolute moron, tyra and erda work on NORMAL HEALTHY HUMANS well not healthy if they got cancer BUT they do not have an overactive fgfr3 yet see immense results, as for ur point on gh, the goverment doesnt see a lot of profit on getting kids on HGH as there are sides such as organomegaly, even if it was side effect free it is not very profitable since not all age groups have open growth plates you moron.

 

[BeatleJuiceFanBoy10]

you are an absolute moron, tyra and erda work on NORMAL HEALTHY HUMANS well not healthy if they got cancer BUT they do not have an overactive fgfr3 yet see immense results, as for ur point on gh, the goverment doesnt see a lot of profit on getting kids on HGH as there are sides such as organomegaly, even if it was side effect free it is not very profitable since not all age groups have open growth plates you moron.

dang you called me a moron twice, just goes to proof my point. There are no studies proving it works on normal humans and there are studies showing that HGH on a large scale dont work. Now go back to the pile of dung you crawled out of.

 

[exsttttt]

dang you called me a moron twice, just goes to proof my point. There are no studies proving it works on normal humans and there are studies showing that HGH on a large scale dont work. Now go back to the pile of dung you crawled out of.

yk what? yeah ur right, all these pathways are cope and all the data is false, actually there are no data like u said. now lets just rewind back to ur first message, proves my point, firstly ur english is dogshit, secondly, u dont even know which receptors cause achondroplasia, let alone have done research to prove that there arent studies showing the drugs work. jfl

 

[BeatleJuiceFanBoy10]

yk what? yeah ur right, all these pathways are cope and all the data is false, actually there are no data like u said. now lets just rewind back to ur first message, proves my point, firstly ur english is dogshit, secondly, u dont even know which receptors cause achondroplasia, let alone have done research to prove that there arent studies showing the drugs work. jfl

English is not my first language and idgaf about what you think about my english. FGFR gain of function mutation causes achondroplasia ofcourse its not the only cause just like these drugs do not always not work. But odds are that a normal person it wont work on, you didnt provide any study showing it worked either. So plz go to school instead of staying around these forums getting fed misinformation

 

[BeatleJuiceFanBoy10]

yk what? yeah ur right, all these pathways are cope and all the data is false, actually there are no data like u said. now lets just rewind back to ur first message, proves my point, firstly ur english is dogshit, secondly, u dont even know which receptors cause achondroplasia, let alone have done research to prove that there arent studies showing the drugs work. jfl

On the first one I was asking you for your research, like I said a while ago if you actually paid attention to the convo. However you never provided any type of evidence of it working

 

[exsttttt]

English is not my first language and idgaf about what you think about my english. FGFR gain of function mutation causes achondroplasia ofcourse its not the only cause just like these drugs do not always not work. But odds are that a normal person it wont work on, you didnt provide any study showing it worked either. So plz go to school instead of staying around these forums getting fed misinformation

getting fed misinformation? lol the following is the easiest data u can find just by typing erdafitinib adolscent growth plates on fucking google, but i dont even think u can read a simple graph but here we go:

Accelerated Linear Growth during Erdafitinib Treatment: An FGFR-Related, but Growth Factor and Sex Steroid-Independent Mechanism? - PMC

Growth acceleration during postnatal growth only occurs during puberty as a physiological event and during catch-up growth mediated by growth-promoting therapies in growth disorders. Here we report on novel observations of skeletal symptoms during ...

pmc.ncbi.nlm.nih.gov

 

[BeatleJuiceFanBoy10]

getting fed misinformation? lol the following is the easiest data u can find just by typing erdafitinib adolscent growth plates on fucking google, but i dont even think u can read a simple graph but here we go:

Accelerated Linear Growth during Erdafitinib Treatment: An FGFR-Related, but Growth Factor and Sex Steroid-Independent Mechanism? - PMC

Growth acceleration during postnatal growth only occurs during puberty as a physiological event and during catch-up growth mediated by growth-promoting therapies in growth disorders. Here we report on novel observations of skeletal symptoms during ...

pmc.ncbi.nlm.nih.gov

Two kids with cancer as sample lmao, if you think this also applies to you. You are indeed getting fed misinformation.

 

[exsttttt]

Two kids with cancer as sample lmao, if you think this also applies to you. You are indeed getting fed misinformation.

the fact that they had cancer makes it even more bulletproof, u dont grow like crazy when u have cancer do you, besides GH was being administered which produced not very signficant increases in velocity, as soon as erda was introduced, you can see the results. this is the most bulletproof paper to prove the drug works. again if you think this is not enough proof, then by all means go fuck urself, talkin about getting fed misinformation while saying " i heard it doesnt work for people who genetically have too much of those receptors" jfl

achondroplasia is induced by OVERACTIVE receptors, a gain of function, not simply more receptors.

not gonna keep arguing with a mentally retarded faggot go fuck urself

 

[BeatleJuiceFanBoy10]

the fact that they had cancer makes it even more bulletproof, u dont grow like crazy when u have cancer do you, besides GH was being administered which produced not very signficant increases in velocity, as soon as erda was introduced, you can see the results. this is the most bulletproof paper to prove the drug works. again if you think this is not enough proof, then by all means go fuck urself, talkin about getting fed misinformation while saying " i heard it doesnt work for people who genetically have too much of those receptors" jfl

achondroplasia is induced by OVERACTIVE receptors, a gain of function, not simply more receptors.

not gonna keep arguing with a mentally retarded faggot go fuck urself

Yeah neither am I with you, you have no concept what medicine terms or scientific research means. Yet you make outrageous claims about drugs. Plz go hide in a corner and never come out for society's sake

 

[lmnopq]

yep i did

You advertise a site that is blatantly scamming. No cnp analogue is being sold for only 175 a kit. Extend.wtf is obviously a fake scam sight someone needs to ban you