HDAC Inhibition during puberty -epigenetic enhancement of growth and development

hdac inhibitors could be used to boost natural growth + development during puberty

not like gh or steroids — this is epigenetic, not hormonal
basically you’re not forcing growth, you’re just taking the brakes off your dna during the time your body’s already trying to grow


what’s an hdac inhibitor?
hdacs = enzymes that keep certain genes “switched off” by tightening the dna

when you inhibit them, the dna loosens and more genes can activate — especially ones involved in bone growth, muscle development, and facial structure

so instead of adding more hormones, you just make your existing growth system work better

why puberty matters:

puberty is the only time where:

your growth plates are open (so bones can still lengthen)
testosterone is increasing naturally
face bones are shaping (jawline, cheekbones etc)
muscles respond better to training and diet
tissue remodels faster

hdac inhibitors during this window could (in theory) amplify all that

possible benefits of hdac inhibition during puberty (if done right):

denser bones (better cheekbones, jaw, orbital rims)
slightly taller height (growth plates stay active longer)
more lean muscle growth from same test levels
faster tissue recovery/remodeling
long-term changes that might stick (epigenetic memory)

what compounds do this?
these are drugs already used in medicine (like for epilepsy or cancer):

valporic acid (VPA) – known hdac inhibitor
vorinostat / trichostatin A – very potent, mostly research use
givinostat – newer, more selective version

most of these are not safe for casual use — they affect brain chemistry and other systems, so any actual use would have to be super controlled and spaced out (like once every few weeks in microdoses)

example theoretical use (vpa):

250–500mg per day for 5–7 days
then take 2–3 weeks off
only during early–mid puberty (13–17)
idea is to hit short windows without causing damage

why it’s interesting:
hdac inhibition isn’t about adding more fuel (like gear) it’s about removing the limiters your dna puts on certain growth genes
it could make your natural growth hit harder, without pushing it past your genetic limit
@jeff1234
 
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Damn so u just dumped some money to India and didn’t get shit
well i got a trackng number I might have jsut gotten unlucky bc it didnt pass customs bc india is so fucking shit at packaging at least chinese UGLs can pack it somewhat discretely.
 
come on bud give me some lenience, they sell furosemide and i bought a sht ton from there.
dam lol here lasix is sold in normal pharmacies
 
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combining hdac inhibitors with pth analogs and hormones during puberty could amplify bone growth

hdac inhibitors unlock growth genes, pth analogs directly stimulate bone formation

and hormones like test/gh fuel the whole process; it’d be a high-risk, high-reward stack if timed perfectly, but could easily cause permanent dysregulation if misused.
i'm already on roids, u think ill benefit if i take like 1g off sodium valproate for 7-8 days and hop off for 2 weeks and repeat (17yo btw)
 
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i'm already on roids, u think ill benefit if i take like 1g off sodium valproate for 7-8 days and hop off for 2 weeks and repeat (17yo btw)
are your growth plates still open or closed
 
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hdac inhibitors could be used to boost natural growth + development during puberty

not like gh or steroids — this is epigenetic, not hormonal
basically you’re not forcing growth, you’re just taking the brakes off your dna during the time your body’s already trying to grow


what’s an hdac inhibitor?
hdacs = enzymes that keep certain genes “switched off” by tightening the dna

when you inhibit them, the dna loosens and more genes can activate — especially ones involved in bone growth, muscle development, and facial structure

so instead of adding more hormones, you just make your existing growth system work better

why puberty matters:

puberty is the only time where:

your growth plates are open (so bones can still lengthen)
testosterone is increasing naturally
face bones are shaping (jawline, cheekbones etc)
muscles respond better to training and diet
tissue remodels faster

hdac inhibitors during this window could (in theory) amplify all that

possible benefits of hdac inhibition during puberty (if done right):

denser bones (better cheekbones, jaw, orbital rims)
slightly taller height (growth plates stay active longer)
more lean muscle growth from same test levels
faster tissue recovery/remodeling
long-term changes that might stick (epigenetic memory)

what compounds do this?
these are drugs already used in medicine (like for epilepsy or cancer):

valporic acid (VPA) – known hdac inhibitor
vorinostat / trichostatin A – very potent, mostly research use
givinostat – newer, more selective version

most of these are not safe for casual use — they affect brain chemistry and other systems, so any actual use would have to be super controlled and spaced out (like once every few weeks in microdoses)

example theoretical use (vpa):

250–500mg per day for 5–7 days
then take 2–3 weeks off
only during early–mid puberty (13–17)
idea is to hit short windows without causing damage

why it’s interesting:
hdac inhibition isn’t about adding more fuel (like gear) it’s about removing the limiters your dna puts on certain growth genes
it could make your natural growth hit harder, without pushing it past your genetic limitlook at this thread
Mirin new drugs
 
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I will take Test E, HGH, HPAC inhibitor, PTH analog, AI and everything that could help me ascend and report back. I have nothing to lose but i don't expect much since im 18. If anyone has researched more about this dm me.
 
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I will take Test E, HGH, HPAC inhibitor, PTH analog, AI and everything that could help me ascend and report back. I have nothing to lose but i don't expect much since im 18. If anyone has researched more about this dm me.
Update
 

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