Dave1
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Disclaimer:
This thread is for informational purposes only.
The use of any medications, including growth hormones, aromatase inhibitors (like anastrozole or letrozole), or other drugs, for the purpose of increasing height should only be done under the supervision of a qualified healthcare professional.
Self-prescribing or using medications without medical guidance can lead to serious health risks, including but not limited to hormonal imbalances, bone health issues, and long-term complications.
Using these drugs for non-medical purposes, such as attempting to increase height in healthy individuals, can result in unintended consequences and potential legal implications.
If you or someone you know is considering any form of height-enhancing treatment, it is essential to consult with a licensed healthcare provider (such as an endocrinologist) to discuss the risks, benefits, and suitability of such treatments.
The information shared in this thread is not intended as medical advice. Always seek professional guidance before making decisions related to medications or treatments.
All these drugs are to be used throughout the whole heightmaxxing timeframe except anavar. Doses of all these drugs can vary. There is no one-size-fits-all approach, and the doses given here are just examples.
These drugs will provide an increase in adult height ONLY if your growth plates are open.
Do NOT use anavar if you cannot use testosterone. Anavar will cause suppression of testosterone, the TRT dose is there to replace the testosterone you will not have once you start using anavar. Either use all of the drugs listed or only use HGH + AI.
Testosterone
(WARNING: WILL SUPRESS HPTA, PCT NECESSERY AFTER HEIGHTMAXXING PROTCOL ENDS)
(use only if you're ok with the risks, not compulsory)
Binds to androgen receptors (AR) on chondrocytes within long bones. Promotes chondrocyte proliferation, differentiation, and maturation. This causes hypertrophy in long bones causing growth. Testosterone works synergistically with HGH since it increases growth hormone receptor expression in chondrocytes, increasing localised igf1 production. (1)
Usage:
Can differ between people but usually just above TRT dose such as 125 to 200mg. Pinning ED is important for stable testosterone blood levels.
Recommended regimen: 150mg testosterone cypionate pinned ED.
HGH (2)
HGH goes to your liver and makes it produce IGF-1. IGF1 directly promotes growth through chondrocyte proliferation and differentiation in the growth plates, leading to bone lengthening and height increase. However using IGF1 LR3 is suboptimal BECAUSE: chondrocytes have localised HGH receptors meaning when HGH binds to the IGF-1R receptors on chondrocytes it further stimulates local production of IGF1 directly promoting growth.
Recommended regimen: 5 (min) to 10 ius pinned ED before bed.
Anavar (3)
(WARNING: WILL SUPRESS HPTA, PCT NECESSERY AFTER HEIGHTMAXXING PROTCOL ENDS)
Increases protein synthesis, also in cartilage on long bones, contributing to elongation of bones.
Recommended regimen as used in study (3): 0.25 mg/kg/day e.g, if you're 65kg: 16.25mg ED
Anavar however is hepatoxic, to avoid this you can use anavar for 10 weeks then 10 weeks off. Counteracting hepatoxicity can be done with: (ran while on anavar)
- Milk thistle
- NAC
- TUDCA
Aromatase inhibitors (AI):
Many AI's exist however studies on anastrozole prove it's effectiveness (4)
AI's are used since when testosterone is produced, it's converted into estrogen. Estrogen binds to receptors on growth plate chondrocytes such as ERα and ERβ. This promotes conversion of chondrocytes into osteoblasts. This change from cartilate to bone leads to the closure of growth plates. Furthermore, estrogen triggers apoptosis in growth plate cartilage cells. This contributes to the gradual disapearance of cartilage and the formation of bone, leading to growth plate fusion. For this reason AI's such as anastrozole are used since they reduce the conversion of testosterone to estrogen by reducing the amount of 5a reductase which is an enzyme that converts testosterone to estrogen.
Estrogen closes growth plates (5)
Recommended regimen: 1mg ED, however blood tests can give a more precise dose as you want your estrogen to be between 10 to 15pg/mL.
Another AI that can be used is letrozole, studies prove IT'S effectiveness aswell. (6)
Recommended regimen: 1mg ED
(1)
Pubertal growth and epiphyseal fusion - PMC
The complex networks of nutritional, cellular, paracrine, and endocrine factors are closely related with pubertal growth and epiphyseal fusion. Important influencing factors include chondrocyte differentiation capacity, multiple molecular pathways ...
pmc.ncbi.nlm.nih.gov
(2)
Growth hormone significantly increases the adult height of children with idiopathic short stature: comparison of subgroups and benefit - PMC
Children with Idiopathic Short Stature do not attain a normal adult height. The improvement of adult height with treatment with recombinant human growth hormone (rhGH), at doses of 0.16 to 0.28 mg/kg/week is modest, usually less that 4 cm, and they ...
pmc.ncbi.nlm.nih.gov
"The age at start of treatment ranged between 4.7 years and 16 years, 11.9 ± 3.3 years for the 68 males and 12 ± 1.9 years for the 20 females."
(3)
Studies of anabolic steroids: v. effect of prolonged oxandrolone administration on growth in children and adolescents with uncomplicated short stature - PubMed
A total of 130 patients with uncomplicated short stature (4 to 17 years of age) were treated with oxandrolone, 0.25 mg/kg/day, for up to four years. Oxandrolone therapy resulted in a two-fold increase in mean growth velocity in the first six months of therapy and was an effective growth...
pubmed.ncbi.nlm.nih.gov
(4)
Anastrozole increases predicted adult height of short adolescent males treated with growth hormone: a randomized, placebo-controlled, multicenter trial for one to three years - PubMed
Anastrozole increases adult height potential of adolescent boys on GH therapy while maintaining normal pubertal progression after 2-3 yr. This treatment offers an alternative in promoting growth in GH-deficient boys in puberty. Long-term follow up is needed to elucidate fully the safety and...
pubmed.ncbi.nlm.nih.gov
(5)
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(6)
Letrozole Effect on Final Height of Patients with Constitutional Delay of Growth and Puberty - PMC
The inhibitory effect of aromatase on predicted adult height and near final height has been studied in patients with constitutional delay of growth and puberty (CDGP). This is the first study aimed at verifying the letrozole (Lz) effect on final ...
pmc.ncbi.nlm.nih.gov
(pls rep
)
