Corpuscula
5'9 heightseeker
- Joined
- Oct 31, 2024
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I'm tired of tryna make my threads look good, so I'll get straight to the point.
- Lithium for heightmaxxing
" After treated by inhibitor SB86[the GSK-3B inhibitor], the overall length of growth plate was not changed. However, growth of tibia in SB86 group was increased by 31 %, the length of resting and proliferating was increased 13 %, whereas the length of hypertrophic was decreased by 57 %. Besides, the mineralized length was found to be significant longer than the control group."
This proves that GSK-3B is detrimental to height growth and that inhibiting it will result in you being taller.
But it's not all there is to it.
GSK-3B is a negative regulator of the WNT pathway, activating the WNT pathway will make your bones grow more but also inhibit adipogenesis (can't create fat tissue) while not being detrimental to bone growth (which is one of the very few things that can do both at the same time, by the way)
We all know that more adipose tissue ('fat') = More Aromatase = More aromatase activity = More estrogen = Your epiphysis closes faster so you end up with a shorter final adult height. So, by reducing estrogen, Lithium can indirectly make you taller through another way.
- Lithium for other stuff
So it will help you in both ways.
But it seems that Lithium is biphasic so you can't just take more for more effects, there is a dose that works the best for it.
By the way, Lithium will also improve muscle fatigue resistance.
"Conversely, GSK3 inhibition is required for IGF‐1 induced myotube hypertrophy (Rommel et al., 2001)"
Meaning that Lithium may also help you build muscle, myotubes are immature multinucleated muscle cells.
And they eventually turn into muscle fibers.
Maybe Lithium goes beyond heightmaxxing and could also help you ascend?
- Dose:
10mg/kg/day, it's lower than the therapeutic dose but has been shown to still affect GSK-3B and other stuff.
- Lithium for heightmaxxing
" After treated by inhibitor SB86[the GSK-3B inhibitor], the overall length of growth plate was not changed. However, growth of tibia in SB86 group was increased by 31 %, the length of resting and proliferating was increased 13 %, whereas the length of hypertrophic was decreased by 57 %. Besides, the mineralized length was found to be significant longer than the control group."
This proves that GSK-3B is detrimental to height growth and that inhibiting it will result in you being taller.
But it's not all there is to it.
GSK-3B is a negative regulator of the WNT pathway, activating the WNT pathway will make your bones grow more but also inhibit adipogenesis (can't create fat tissue) while not being detrimental to bone growth (which is one of the very few things that can do both at the same time, by the way)
We all know that more adipose tissue ('fat') = More Aromatase = More aromatase activity = More estrogen = Your epiphysis closes faster so you end up with a shorter final adult height. So, by reducing estrogen, Lithium can indirectly make you taller through another way.
- Lithium for other stuff
So it will help you in both ways.
But it seems that Lithium is biphasic so you can't just take more for more effects, there is a dose that works the best for it.
By the way, Lithium will also improve muscle fatigue resistance.
"Conversely, GSK3 inhibition is required for IGF‐1 induced myotube hypertrophy (Rommel et al., 2001)"
Meaning that Lithium may also help you build muscle, myotubes are immature multinucleated muscle cells.
And they eventually turn into muscle fibers.
Maybe Lithium goes beyond heightmaxxing and could also help you ascend?
- Dose:
10mg/kg/day, it's lower than the therapeutic dose but has been shown to still affect GSK-3B and other stuff.
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