Corpuscula
5'9 heightseeker
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I researched more about it and it really seems lithium can make you grow taller?I'm tired of tryna make my threads look good, so I'll get straight to the point.
- Lithium for heightmaxxing
" After treated by inhibitor SB86[the GSK-3B inhibitor], the overall length of growth plate was not changed. However, growth of tibia in SB86 group was increased by 31 %, the length of resting and proliferating was increased 13 %, whereas the length of hypertrophic was decreased by 57 %. Besides, the mineralized length was found to be significant longer than the control group."
This proves that GSK-3B is detrimental to height growth and that inhibiting it will result in you being taller.
But it's not all there is to it.
GSK-3B is a negative regulator of the WNT pathway, activating the WNT pathway will make your bones grow more but also inhibit adipogenesis (can't create fat tissue) while not being detrimental to bone growth (which is one of the very few things that can do both at the same time, by the way)
We all know that more adipose tissue ('fat') = More Aromatase = More aromatase activity = More estrogen = Your epiphysis closes faster so you end up with a shorter final adult height. So, by reducing estrogen, Lithium can indirectly make you taller through another way.
- Lithium for other stuff
So it will help you in both ways.
But it seems that Lithium is biphasic so you can't just take more for more effects, there is a dose that works the best for it.
By the way, Lithium will also improve muscle fatigue resistance.
"Conversely, GSK3 inhibition is required for IGF‐1 induced myotube hypertrophy (Rommel et al., 2001)"
Meaning that Lithium may also help you build muscle, myotubes are immature multinucleated muscle cells.
And they eventually turn into muscle fibers.
Maybe Lithium goes beyond heightmaxxing and could also help you ascend?
- Dose:
10mg/kg/day, it's lower than the therapeutic dose but has been shown to still affect GSK-3B and other stuff.
yeah, it's also used to treat bipolar disorderLike the stuff in batteries?
i'll take anything at this point to get taller honestly might convince me to chew on batteriesI'm tired of tryna make my threads look good, so I'll get straight to the point.
- Lithium for heightmaxxing
" After treated by inhibitor SB86[the GSK-3B inhibitor], the overall length of growth plate was not changed. However, growth of tibia in SB86 group was increased by 31 %, the length of resting and proliferating was increased 13 %, whereas the length of hypertrophic was decreased by 57 %. Besides, the mineralized length was found to be significant longer than the control group."
This proves that GSK-3B is detrimental to height growth and that inhibiting it will result in you being taller.
But it's not all there is to it.
GSK-3B is a negative regulator of the WNT pathway, activating the WNT pathway will make your bones grow more but also inhibit adipogenesis (can't create fat tissue) while not being detrimental to bone growth (which is one of the very few things that can do both at the same time, by the way)
We all know that more adipose tissue ('fat') = More Aromatase = More aromatase activity = More estrogen = Your epiphysis closes faster so you end up with a shorter final adult height. So, by reducing estrogen, Lithium can indirectly make you taller through another way.
- Lithium for other stuff
So it will help you in both ways.
But it seems that Lithium is biphasic so you can't just take more for more effects, there is a dose that works the best for it.
By the way, Lithium will also improve muscle fatigue resistance.
"Conversely, GSK3 inhibition is required for IGF‐1 induced myotube hypertrophy (Rommel et al., 2001)"
Meaning that Lithium may also help you build muscle, myotubes are immature multinucleated muscle cells.
And they eventually turn into muscle fibers.
Maybe Lithium goes beyond heightmaxxing and could also help you ascend?
- Dose:
10mg/kg/day, it's lower than the therapeutic dose but has been shown to still affect GSK-3B and other stuff.
nettspend refFuck cancer
My nose is normal so I don’t care if it grows that much. If it’s that bad then I can always get a rhino
IF only I had a scientist friend who I could pay to get KY13982 and vosoride for me
?nettspend ref
send wtv u foundI researched more about it and it really seems lithium can make you grow taller?
probally very minimal but shit I'll take anything
How will he get ectopic calcification if everything is dosed correctly? Vosortide doesn’t even effect osteoblast differentiation or cartilage that aren’t in epiphesial platesBro ur gonna be famous for overdosing on a height stack, even if u take every possible ancillaries and do everything correctly ectopic calcification and tumorigenesis are both almost guaranteed cause of the paths affected by the stack
I mean it definitely could make u tall if ur young enough, and if ur gonna take all those than u may aswell take everything there is
Ill reply to part of this cuz i feel i have to even tho its retarded, first ectopic isnt dependent on direct effects from either of those 2 things, also dosing doesnt account for individual variables in endo + para signals, even if u micro manage doses too much gp stim would still cause mineralelaization issues especially if runx2 is activated offtarget, also he listed multiple drugs not just 1 i didnt specifically say voso does this i said stacking any drug will still cause an overlap in pathsHow will he get ectopic calcification if everything is dosed correctly? Vosortide doesn’t even effect osteoblast differentiation or cartilage that aren’t in epiphesial plates
Rigged I have ape brain and am likely medically classified as retared if I ever got tested so thank you for replying to me. What I am saying is that (in my thought process) at reasonable doses of gh this shouldn’t cause too much ectopic bone growth. Besides gh I could see very high doses of ky causing ectopic growth but again that would be at reasonably large dosages. Also saying “depending on parathyroid and endocrinological factors” is a little bit water in my opinion because most peoples values in blood tests won’t fall super outside reference ranges for most endocrinological and parathyroid blood panels and if they did it’s likely they would know. What pathways cross from ky and voso? If you reply thank you again, I have few synapses within my skull cavity and need guidance on my heightmaxxing journey (pinning untested raw powders from made-in-china.com)Ill reply to part of this cuz i feel i have to even tho its retarded, first ectopic isnt dependent on direct effects from either of those 2 things, also dosing doesnt account for individual variables in endo + para signals, even if u micro manage doses too much gp stim would still cause mineralelaization issues especially if runx2 is activated offtarget, also he listed multiple drugs not just 1 i didnt specifically say voso does this i said stacking any drug will still cause an overlap in paths
wake up to geneticsI'm tired of tryna make my threads look good, so I'll get straight to the point.
- Lithium for heightmaxxing
" After treated by inhibitor SB86[the GSK-3B inhibitor], the overall length of growth plate was not changed. However, growth of tibia in SB86 group was increased by 31 %, the length of resting and proliferating was increased 13 %, whereas the length of hypertrophic was decreased by 57 %. Besides, the mineralized length was found to be significant longer than the control group."
This proves that GSK-3B is detrimental to height growth and that inhibiting it will result in you being taller.
But it's not all there is to it.
GSK-3B is a negative regulator of the WNT pathway, activating the WNT pathway will make your bones grow more but also inhibit adipogenesis (can't create fat tissue) while not being detrimental to bone growth (which is one of the very few things that can do both at the same time, by the way)
We all know that more adipose tissue ('fat') = More Aromatase = More aromatase activity = More estrogen = Your epiphysis closes faster so you end up with a shorter final adult height. So, by reducing estrogen, Lithium can indirectly make you taller through another way.
- Lithium for other stuff
So it will help you in both ways.
But it seems that Lithium is biphasic so you can't just take more for more effects, there is a dose that works the best for it.
By the way, Lithium will also improve muscle fatigue resistance.
"Conversely, GSK3 inhibition is required for IGF‐1 induced myotube hypertrophy (Rommel et al., 2001)"
Meaning that Lithium may also help you build muscle, myotubes are immature multinucleated muscle cells.
And they eventually turn into muscle fibers.
Maybe Lithium goes beyond heightmaxxing and could also help you ascend?
- Dose:
10mg/kg/day, it's lower than the therapeutic dose but has been shown to still affect GSK-3B and other stuff.
ripRigged I have ape brain and am likely medically classified as retared if I ever got tested so thank you for replying to me.
GH doesnt work on its own it affects igf which has pleiotropic affects on tissue, it also stims osteoblast activity systemically, in scenerios where some specific things exist it would contribute to ectopicWhat I am saying is that (in my thought process) at reasonable doses of gh this shouldn’t cause too much ectopic bone growth.
No at any dose KY being a Wnt/B activator predisposes it to osteogenesis at pretty much any doseBesides gh I could see very high doses of ky causing ectopic growth but again that would be at reasonably large dosages.
Ur right for the most part but ur forgetting localized environments in ectopic cal, systemic bloods wont show subtle imbalances in PTHAlso saying “depending on parathyroid and endocrinological factors” is a little bit water in my opinion because most peoples values in blood tests won’t fall super outside reference ranges for most endocrinological and parathyroid blood panels and if they did it’s likely they would know.
BMP/Wnt, KY activates BMP which is already indirectly upgregulared by voso supressing FGFR3, both of them also interacy with RUNX2, and igf boosts both BMP/WNT, which just creates a feedback loopWhat pathways cross from ky and voso?
For sure man, tbh just stick to the basics if ur young enough more will be better for height but itll also be more expensive and riskierIf you reply thank you again, I have few synapses within my skull cavity and need guidance on my heightmaxxing journey (pinning untested raw powders from made-in-china.com)
Thanks man. I understand the igf-1 conversion of gh but in my opinion if you only dose at night and stay away from long half life ghrps and ghrhs it seems pretty hard to get acromegaly. The few cases I have seen of people actually getting acromegaly from heightmaxxing attempts have almost all involved cjc-dac which half life is over a week. I don’t think it’s possible for your body to convert enough gh to igf-1 if administration is just once daily unless your using some very good somatostatin inhibitors. Also I may be remembering wrong but ky had dose dependent effect on rats od bone growth. Thats what was kinda behind my original through process. I’m getting old man I am already 17 so I don’t think I can get away with just gh and ai to get to 6”3 (5”11 current) altho I am on both. My current aim right now is to induce as much growth to the actual epiphyseal plates and cartilage that I can as of right now since my facial bones are already pretty robust and I would become ogre with more ecto bone growth; I am trying to keep it as longitudinal as possible. Guess dwarf medication vosortritide it is for merip
GH doesnt work on its own it affects igf which has pleiotropic affects on tissue, it also stims osteoblast activity systemically, in scenerios where some specific things exist it would contribute to ectopic
No at any dose KY being a Wnt/B activator predisposes it to osteogenesis at pretty much any dose
Ur right for the most part but ur forgetting localized environments in ectopic cal, systemic bloods wont show subtle imbalances in PTH
BMP/Wnt, KY activates BMP which is already indirectly upgregulared by voso supressing FGFR3, both of them also interacy with RUNX2, and igf boosts both BMP/WNT, which just creates a feedback loop
For sure man, tbh just stick to the basics if ur young enough more will be better for height but itll also be more expensive and riskier
yeah ur right we should now delete the whole website since 500 said sowake up to genetics
I know your joking
the thread isnt a joke...I know your joking
But low dose lithium has so many benefits