Hgh only with open plates

[ttrragz]

I have read the hgh 101 thread and several others. I am confused as I keep seeing that there is an indirect correlation with hgh possibly increasing estradiol but I want to know if that’s true and is AI really needed during

 

[tensor]

No, rhGH does not convert to estrogen because it doesn’t aromatize. That only applies to some androgens.

Use non-steroid based aromatase inhibitors alongside it to delay growth plate closure.

 

[ttrragz]

No, rhGH does not convert to estrogen because it doesn’t aromatize. That only applies to some androgens.

Use non-steroid based aromatase inhibitors alongside it to delay growth plate closure.

Yes not convert but indirectly can increase activity it says here

Growth hormone (GH) activity is associated with increased serum oestradiol and reduced anti-Müllerian hormone in healthy male volunteers treated with GH and a GH antagonist - PubMed

Growth hormone (GH) and insulin-like growth factor I (IGF-I) receptors are present on pituitary gonadotrophs and on testicular Leydig and Sertoli cells. Thus, the GH/IGF-I system may modulate the pituitary-gonadal axis in males. This is a randomized cross-over study. Eight healthy male...

pubmed.ncbi.nlm.nih.gov

 

[ttrragz]

bump

 

[yordancel]

I have read the hgh 101 thread and several others. I am confused as I keep seeing that there is an indirect correlation with hgh possibly increasing estradiol but I want to know if that’s true and is AI really needed during

Hgh is more likely to give you premature epiphyseal closure if you're not deficient pal

 

[yordancel]

Hgh is more likely to give you premature epiphyseal closure if you're not deficient pal

I have read the hgh 101 thread and several others. I am confused as I keep seeing that there is an indirect correlation with hgh possibly increasing estradiol but I want to know if that’s true and is AI really needed during

If you pair hgh with other compounds like aromatase inhibs and fgfr3 inhibs then there's a good chance it could work for you. Don't walk in empty or you're cucking your growth

 

[terlound]

I have read the hgh 101 thread and several others. I am confused as I keep seeing that there is an indirect correlation with hgh possibly increasing estradiol but I want to know if that’s true and is AI really needed during

HGH has been shown to decrease final adult height, it speeds up growth velocity but ALSO bone maturation, this is why when its clinically used its pretty much ALWAYS been paired with an aromatise inhibitor. if u want evidence of this lmk i can link u some studies

 

[ttrragz]

If you pair hgh with other compounds like aromatase inhibs and fgfr3 inhibs then there's a good chance it could work for you. Don't walk in empty or you're cucking your growth

do you think it would be fine if I only took hgh and ai no fgfr3 inhib? Cause their expensive

 

[ttrragz]

HGH has been shown to decrease final adult height, it speeds up growth velocity but ALSO bone maturation, this is why when its clinically used its pretty much ALWAYS been paired with an aromatise inhibitor. if u want evidence of this lmk i can link u some studies

Sure send me some

 

[terlound]

Comparative efficacy of growth hormone, aromatase inhibitors, and gonadotropin-releasing hormone agonists in idiopathic short stature with advanced bone age | ECEESPE2025 | Joint Congress of the European Society for Paediatric Endocrinology (ESPE)

www.endocrine-abstracts.org

Frontiers | Evolving growth hormone deficiency: proof of concept

We present the evolution of GHD in adolescent males with persistent growth failure, in whom the diagnosis was established after a second GH stimulation test ...

www.frontiersin.org

Aromatase Inhibitors Treatment Alone or with GH Increases Final Height in Short-statured Pubertal Boys - Real-world Data

cris.tau.ac.il

most these sources disagree with me actually i think i was wrong. it doesnt decrease final adult height but it proportionally ages ur bones with the height you get, so ur final adult height stays around the same. ALL of the sources agree that aromatise inhibitors + hgh increase final height by a significant margin, rather than just hgh which i think gives an average of +0.5cm on final adult height