High IQ excerpt from hair loss forum

[Carolus]

A few reasons for hair loss include:

1. Androgen receptor polymorphisms and differences in androgen receptor concentrations and steroid-converting enzymes as the principal contributors to male androgenic alopecia (R).
2. Derangement of the internal cellular environment is primarily caused by the accumulation of free radicals, the reactive oxygen species (ROS) along with poor repair and restoration of the damaged cells due to essential nutrient deficiencies.
3. “An initial experimental study by Eun[40] discovered that DHT does not directly cause inhibition of hair growth but it induces the release of transforming growth factor beta 1 (TGFß1) which results in the miniaturization and hair loss. Shin et al.[41] followed this research further with cultured androgen sensitive dermal papilla cells and the addition of DHT to this androgen sensitive cell caused an accumulation of free radicles ROS within the cultured cells, which in turn induced the release of TGFß1.” So a better approach than lowering DHT is to:
   • Positively modulate the skin microbiome (think sunlight, micronutrients, clean environment, etc.)
   • Inhibit excess ROS production
   • Prevent excess activation of TGFß1
   • Reduce stress

Entire thread: https://www.hairlosstalk.com/intera...t-finasteride-side-effects-eventually.130765/

Read the thread before you comment something stupid like ''finasteride has no sides''

 

[fras]

 

[redfacccee]

so basically a reason why every incel is balding is bc they dont go outside gotcha bro

 

[Deleted member 14543]

A few reasons for hair loss include:

1. Androgen receptor polymorphisms and differences in androgen receptor concentrations and steroid-converting enzymes as the principal contributors to male androgenic alopecia (R).
2. Derangement of the internal cellular environment is primarily caused by the accumulation of free radicals, the reactive oxygen species (ROS) along with poor repair and restoration of the damaged cells due to essential nutrient deficiencies.
3. “An initial experimental study by Eun[40] discovered that DHT does not directly cause inhibition of hair growth but it induces the release of transforming growth factor beta 1 (TGFß1) which results in the miniaturization and hair loss. Shin et al.[41] followed this research further with cultured androgen sensitive dermal papilla cells and the addition of DHT to this androgen sensitive cell caused an accumulation of free radicles ROS within the cultured cells, which in turn induced the release of TGFß1.” So a better approach than lowering DHT is to:
   • Positively modulate the skin microbiome (think sunlight, micronutrients, clean environment, etc.)
   • Inhibit excess ROS production
   • Prevent excess activation of TGFß1
   • Reduce stress

Entire thread: https://www.hairlosstalk.com/intera...t-finasteride-side-effects-eventually.130765/

Read the thread before you comment something stupid like ''finasteride has no sides''

in laymans terms?

 

[PURE ARYAN GENETICS]

nice. tldr guide?