How I Defeated Acne & Making Massive Progress Towards Glass Skin: My Story, My Lessons, My Advice.

[yesimog420]

@yesimog420 @org3cel.RR @Scriggan @2marc1

Beautiful thread thank you

 

[ultimatebpconsumer]

this thread made me bust all over my screen tbh

 

[Napoleon1800]

Introduction
Unfortunately, most of my looksmaxing efforts have been dedicated to the extirpation of comedones. Despite being past my puberty years, comedone formation would persist, and it seemed like no matter what I did, I would never find full relief from it.

• I have tried the stereotypical skincare routine, which consist of; cleansers, moisturizers, and spot treatments.
• I have tried megadosing retinyl palmitate (200,000 IUs/day).
• I have tried using salicylic acid.
• I have tried using Accutane.
• I have tried using spearmint supplements.
• I have tried taking Omega-3 supplements.
• I have tried taking Multivitamins.
• I have tried drinking plenty of water.
• I have tried changing my diet (keto, cutting out certain foods).

Over the course of a little more than a year, and only a few of them have granted me salvation from comedonal acne. Within the past four months, I have accidentally stumbled on a solution which has granted me a pretty solid salvation from comedonal acne. Before I explain the solution I stumbled on, I need to go into the cell and molecular biology of how comedones form.

Comedonal Formation
Androgens are a class of hormones ( play a significant role in hormonal comedonal acne formation, and hormonal acne begins with androgens binding to the androgen receptor of sebocytes. Once the androgen binds to the androgen receptor on a sebocyte, it tells the sebocyte to produce sebum, if you have an excess of free testosterone, your sebocytes can produce an excess amount of sebum.

View attachment 3660453

High levels of free testosterone can be caused by high insulin spikes (diet issue and/or insulin resistance), puberty, anabolic steroids, selective androgen receptor modulators, low levels of sex-hormone binding globulin (SHBG) and/or genetics, among others.

If there is an excess amount of sebum inside of a hair follicle, a harmless bacteria called cutibacterium acnes begins metabolizing the excess sebum, rapidly reproduces, and becomes a problem. Once your white blood cells take note of this, they begin to flood the area and fight the excess bacteria. All of this mess creates pus, and a comedone.

Non-Hormonal Comedone Formation
The probability that you have non-hormonal acne is slim. If you do have non-hormonal acne, chances are, you are applying comedone forming substances on your skin (hair products, skin products, coconut oil, etc.). I recommend that you type every single ingredient you apply on your skin into ChatGPT and ask for comedogenic ratings.

View attachment 3660454

Things That Do Not Work
In my experience, skincare will not defeat acne. At best, it can reduce acne significantly by preventing new breakouts. Omega-3 fatty acids have not helped me, they help reduce inflammation and decrease sebum production, thereby reducing (but not defeating) acne. Same goes for multivitamins, salicylic acid (helps get rid of acne quickly though), cleansers, moisturizers and spot treatments.

View attachment 3660456

Things That Do Work/Help Significantly
A good diet that does not cause a massive insulin spike (does not cause your skin to become greasy or oily 5 minutes after taking a bite) or increases free testosterone levels to excessive levels definitely helps in my experience (I don't know the amount which constitutes excessive free testosterone sadly).

In my case, my acne formation primarily consisted of...

Eat something I should not have eaten -> aggressive insulin spike -> spike in free testosterone -> spike in sebum, often too much -> comedone formation.

Ketogenic diets are what helped me keep relatively clear skin last summer, due to their low carbohydrate content and thus, does not really trigger heavy insulin spikes. The foods I have on my "suspicious" list are: pasta, cheese, bread, rice (especially white) and anything with any form of starch. Those foods consistently give me the greasy face effect indicative of an aggressive insulin spike. Being healthy and eating in such a manner that counteracts metabolic issues like insulin resistance certainly helps.

View attachment 3660458

Retinoids are a class of substances (retinol, tretinoin, isotretinoin, adapalene, retinaldehyde) that increase skin cell turnover (rate of acne healing) and decrease sebum production. Using retinoids are definitely key in defeating acne. I have had good experiences with tretinoin last summer, Vitamin A megadosing (retinyl palmitate, 200,00 IU/day, closest thing to isotretinoin for brokies) and isotretinoin currently. Isotretinoin is by far the strongest sebum production inhibitor I have tried but they all work, and work well.

View attachment 3660466

Spearmint is truly impressive! It increases sex-hormone binding globulin (SHBG), which reduces the amount of free testosterone by binding to testosterone, therefore making it inactive. Think of it like a police officer (SHBG) putting a criminal (testosterone) in a cop car, making the criminal "inactive". With higher SHBG levels, the amount of androgens binding to androgen receptors at sebocytes are reduced significantly. I have taken at least 1000 mg daily for the past 2 weeks now (in supplement form, although spearmint tea works just as well). This has enabled me to eat foods that would have left me looking like a comedone chipped cookie the next day with negligible issues. Yesterday, I ate macaroni and cheese (Chick-fil-A), Little Caesar's Crazy Puffs, and a Chick-fil-A sandwich, with only 1 small acne and 8-10 ultra-small pimples, all which will resolve themselves in 3 days maximum and were barely noticeable. Spearmint is truly a weapon. I'm considering buying spearmint oil and adding a drop into my skincare products. I think the reason I am acne-prone in the first place is a combination of insulin issues and low SHBG.

View attachment 3660467

Being in peak health & having hormone balance is certainly beneficial. Not getting deep, refreshing sleep every night is a health risk in it of itself and it also lowers your SHBG, makes your insulin spikes more intense, and in general, increases your risk for acne by a fair amount due the body's ability to regulate itself being impaired. Master your sleep, nutrition, and fitness habits.

View attachment 3660494


And finally, once you've defeated acne, use Matrixyl, Copper Peptides, Vitamin C Serum, or any other collagen-boosting item and use it for a few months. This will increase your skin's collagen and elastin to glass skin levels! I'm using Matrixyl right now, and used Vitamin C in the past, and they helped so much so quickly!

---

Dear pubertycels: this could inhibit your development.

P.S. I do not really have a skincare routine. I just take Isotretinoin (will swap for retinyl palmitate supplements when I'm done with it) and Spearmint everyday and avoid the suspicious foods listed above, on top of using sunscreen, moisturizer and Matrixyl.

Any ideas on how to clear mild scarring and PIE? I got rid of most of my active acne but these fucking spots won’t go away. My only remaining option seems to be accutane

 

[looks>books]

Do you have progress pics

 

[Cubancel]

good thread botb worthy dnr tho kys

 

[MikeShinoda]

And.. you just use isotretinoin, thats it, everything besides that - water

 

[copernico]

Introducción
Desafortunadamente, la mayoría de mis esfuerzos para maximizar mi apariencia se han dedicado a la extirpación de comedones. A pesar de haber pasado la pubertad, la formación de comedones persistía, y parecía que, hiciera lo que hiciera, nunca encontraría alivio completo.

• He probado la rutina estereotipada de cuidado de la piel, que consiste en: limpiadores, humectantes y tratamientos localizados.
• He probado una megadosis de palmitato de retinilo (200.000 UI/día).
• He probado a usar ácido salicílico.
• He intentado usar Accutane.
• He intentado usar suplementos de menta verde.
• He intentado tomar suplementos de Omega-3.
• He intentado tomar multivitaminas.
• He intentado beber mucha agua.
• He intentado cambiar mi dieta (ceto, eliminando ciertos alimentos).

En poco más de un año, y solo unos pocos me han salvado del acné comedónico. En los últimos cuatro meses, he encontrado accidentalmente una solución que me ha salvado bastante bien del acné comedónico. Antes de explicar la solución que encontré, necesito explicar la biología celular y molecular de la formación de los comedones.

Formación de comedones
Los andrógenos son una clase de hormonas (juegan un papel importante en la formación del acné comedónico hormonal, y el acné hormonal comienza con la unión de los andrógenos al receptor de andrógenos de los sebocitos. Una vez que el andrógeno se une al receptor de andrógenos en un sebocito, le dice al sebocito que produzca sebo; si tiene un exceso de testosterona libre , sus sebocitos pueden producir una cantidad excesiva de sebo.

View attachment 3660453

Los niveles altos de testosterona libre pueden ser causados por picos altos de insulina (problema de dieta y/o resistencia a la insulina), pubertad, esteroides anabólicos, moduladores selectivos del receptor de andrógenos, niveles bajos de globulina transportadora de hormonas sexuales (SHBG) y/o genética, entre otros.

Si hay un exceso de sebo dentro de un folículo piloso, una bacteria inofensiva llamada Cutibacterium acnes comienza a metabolizar el exceso de sebo, se reproduce rápidamente y se convierte en un problema. Una vez que los glóbulos blancos lo detectan, comienzan a inundar la zona y a combatir el exceso de bacterias. Todo este desorden crea pus y un comedón.

Formación de comedones no hormonales
La probabilidad de que tengas acné no hormonal es mínima. Si lo tienes, lo más probable es que te estés aplicando sustancias que forman comedones (productos para el cabello, productos para la piel, aceite de coco, etc.). Te recomiendo que escribas cada ingrediente que te aplicas en ChatGPT y preguntes por su clasificación comedogénica.

View attachment 3660454

Cosas que no funcionan
En mi experiencia, el cuidado de la piel no combate el acné. En el mejor de los casos, puede reducirlo significativamente al prevenir nuevos brotes. Los ácidos grasos omega-3 no me han ayudado; ayudan a reducir la inflamación y la producción de sebo, reduciendo así (pero no combatiendo) el acné. Lo mismo ocurre con los multivitamínicos, el ácido salicílico (aunque ayuda a eliminar el acné rápidamente), los limpiadores, las cremas hidratantes y los tratamientos localizados.

View attachment 3660456

Cosas que sí funcionan/ayudan significativamente
Una buena dieta que no cause un pico masivo de insulina (que no haga que tu piel se vuelva grasosa o aceitosa 5 minutos después de tomar un bocado) o que aumente los niveles de testosterona libre a niveles excesivos definitivamente ayuda en mi experiencia (lamentablemente, no sé la cantidad que constituye un exceso de testosterona libre).

En mi caso, la formación de mi acné consistió principalmente en...

Comí algo que no debería haber comido -> pico agresivo de insulina -> pico de testosterona libre -> pico de sebo, a menudo demasiado -> formación de comedones.

Las dietas cetogénicas me ayudaron a mantener una piel relativamente limpia el verano pasado, gracias a su bajo contenido en carbohidratos, lo que evita picos de insulina intensos. Los alimentos que tengo en mi lista de "sospechosos" son: pasta, queso, pan, arroz (sobre todo blanco) y cualquier alimento con almidón. Estos alimentos me producen constantemente el efecto de cara grasosa, indicativo de un pico de insulina intenso. Mantener una alimentación saludable que contrarreste problemas metabólicos como la resistencia a la insulina sin duda ayuda.

View attachment 3660458

Los retinoides son una clase de sustancias (retinol, tretinoína, isotretinoína, adapaleno, retinaldehído) que aumentan la renovación celular de la piel (la velocidad de curación del acné) y disminuyen la producción de sebo. Usar retinoides es fundamental para combatir el acné. Tuve buenas experiencias con la tretinoína el verano pasado, con megadosis de vitamina A (palmitato de retinilo, 200.000 UI/día, lo más parecido a la isotretinoína para los caballos) y con la isotretinoína actualmente. La isotretinoína es, con diferencia, el inhibidor de la producción de sebo más potente que he probado, pero todos funcionan, y funcionan bien.

View attachment 3660466

¡ La hierbabuena es realmente impresionante! Aumenta la globulina transportadora de hormonas sexuales (SHBG), que reduce la cantidad de testosterona libre al unirse a la testosterona, inactivándola. Imagínatelo como si un policía (SHBG) subiera a un criminal (testosterona) a un coche patrulla, dejándolo "inactivo". Con niveles más altos de SHBG, la cantidad de andrógenos que se unen a los receptores de andrógenos en los sebocitos se reduce significativamente. He tomado al menos 1000 mg al día durante las últimas dos semanas (en suplemento, aunque el té de hierbabuena funciona igual de bien). Esto me ha permitido comer alimentos que al día siguiente me habrían dejado con el aspecto de una galleta con comedones, sin apenas problemas. Ayer comí macarrones con queso (Chick-fil-A), Little Caesar's Crazy Puffs y un sándwich de Chick-fil-A, y solo tuve un pequeño acné y entre 8 y 10 granitos ultrapequeños. Todos se curan solos en 3 días como máximo y apenas se notan. La hierbabuena es un arma poderosa. Estoy considerando comprar aceite de hierbabuena y añadir una gota a mis productos de cuidado facial. Creo que la razón principal por la que tengo tendencia al acné es una combinación de problemas de insulina y una baja concentración de SHBG.

View attachment 3660467

Tener una salud óptima y un equilibrio hormonal es sin duda beneficioso. No dormir profunda y reparadoramente cada noche es en sí mismo un riesgo para la salud, ya que también reduce la SHBG, intensifica los picos de insulina y, en general, aumenta considerablemente el riesgo de acné debido a la disminución de la capacidad del cuerpo para regularse. Domina tus hábitos de sueño, nutrición y ejercicio.

View attachment 3660494


Y finalmente, una vez que hayas vencido el acné, usa Matrixyl, péptidos de cobre, suero de vitamina C o cualquier otro producto que potencie el colágeno y úsalo durante unos meses. ¡Esto aumentará el colágeno y la elastina de tu piel a niveles de cristal! Estoy usando Matrixyl ahora mismo y antes usé vitamina C, ¡y me ayudaron muchísimo enseguida!

---

Queridos pubertycels: esto podría inhibir su desarrollo.

PD: La verdad es que no tengo una rutina de cuidado de la piel. Solo tomo isotretinoína (la cambiaré por suplementos de palmitato de retinilo cuando termine) y hierbabuena todos los días, y evito los alimentos sospechosos mencionados, además de usar protector solar, crema hidratante y Matrixyl.

Don't sunscreens cause skin cancer?

 

[Cyframe]

Hmm interesting, thanks for the guide. Will try implementing it.

 

[Jonasㅤㅤ]

if you have an excess of free testosterone, your sebocytes can produce an excess amount of sebum.

It is fucking DHT causing an upregulation of sebum production, not testosterone.

inb4 he tells the kids here to limit T.

High levels of free testosterone can be caused by high insulin spikes (diet issue and/or insulin resistance), puberty, anabolic steroids, selective androgen receptor modulators, low levels of sex-hormone binding globulin (SHBG) and/or genetics, among others.

Higher levels of free testosterone are caused by reduced SHBG, no other factor plays a major role.

Steroids and SARMs obviously cause drops in SHBG.

Spearmint is truly impressive! It increases sex-hormone binding globulin (SHBG)

Or just take an 5ARi you utter subhuman.

use Matrixyl, Copper Peptides, Vitamin C Serum, or any other collagen-boosting item and use it for a few months.

This will increase your skin's collagen and elastin to glass skin levels!

No shit like you didn't just mention it.

I just take Isotretinoin and Spearmint everyday

Isotretinoin does the major work, not fucking spearmint.

Just take isotretinoin and dutasteride or shoot yourself in the head.

Never write a guide again you fucking AI keyboard warrior.

@chadbeingmade @Eltrē @imontheloose @trenace450 @loyolaxavvierretard @Zagro

 

[imontheloose]

It is fucking DHT causing an upregulation of sebum production, not testosterone.

inb4 he tells the kids here to limit T.

Higher levels of free testosterone are caused by reduced SHBG, no other factor plays a major role.

Steroids and SARMs obviously cause drops in SHBG.

Or just take an 5ARi you utter subhuman.


No shit like you didn't just mention it.

Isotretinoin does the major work, not fucking spearmint.

Just take isotretinoin and dutasteride or shoot yourself in the head.

Never write a guide again you fucking AI keyboard warrior.

@chadbeingmade @Eltrē @imontheloose @trenace450 @loyolaxavvierretard @Zagro

I’m more confused how topical, synthetic forms of vitamin C boost collagen’s production rate. I’ve never heard of it.

 

[enchanted_elixir]

I’m more confused how topical, synthetic forms of vitamin C boost collagen’s production rate. I’ve never heard of it.

Just put it on your skin and see how it goes.

 

[imontheloose]

Just put it on your skin and see how it goes.

I have used vitamin C serums before, quite a couple of the synthetic forms. Any collagen-boost you’re noticing is the consequence of using a retinoid. If I’m wrong, tell me the MOA of the vitamin C boosting collagen. You know the main problem with it and why there is so many forms of it is because it’s incredibly unstable in light and has awful times even getting absorbed into your skin, right? I doubt it’s going to affect collagen in the slightest. I can’t reason it biochemically.

Have the rest of the Mongolian triplets ever heard of this phenomenon? @chadbeingmade @Jonasㅤㅤ

 

[enchanted_elixir]

I have used vitamin C serums before, quite a couple of the synthetic forms. Any collagen-boost you’re noticing is the consequence of using a retinoid. If I’m wrong, tell me the MOA of the vitamin C boosting collagen. You know the main problem with it and why there is so many forms of it is because it’s incredibly unstable in light and has awful times even getting absorbed into your skin, right? I doubt it’s going to affect collagen in the slightest. I can’t reason it biochemically.

Have the rest of the Mongolian triplets ever heard of this phenomenon? @chadbeingmade @Jonasㅤㅤ

I used ascorbic acid, in a black, uv protecting bottle.

 

[chadbeingmade]

Just put it on your skin and see how it goes.

“Just put it on your skin bro and you will see the collagen production rate increase right before your very eyes”

 

[imontheloose]

I used ascorbic acid, in a black, uv protecting bottle.

Yeah but you’re not in a black, light-resistant vial. Still no MOA. Just rub shit on your face and trust me bro.

 

[Jonasㅤㅤ]

I have used vitamin C serums before, quite a couple of the synthetic forms. Any collagen-boost you’re noticing is the consequence of using a retinoid. If I’m wrong, tell me the MOA of the vitamin C boosting collagen. You know the main problem with it and why there is so many forms of it is because it’s incredibly unstable in light and has awful times even getting absorbed into your skin, right? I doubt it’s going to affect collagen in the slightest. I can’t reason it biochemically.

Have the rest of the Mongolian triplets ever heard of this phenomenon? @chadbeingmade @Jonasㅤㅤ

Wanted to mention this point, but our lovely user @enchanted_elixir is most likely just baiting with his guides.

There is no way he recommends spearmint to decrease testosterone or free T to combat acne.

It's like buying a truck to transport a kitten instead of a transport box for cats.

The @truthhurts

@chadbeingmade

 

[enchanted_elixir]

“Just put it on your skin bro and you will see the collagen production rate increase right before your very eyes”
View attachment 3860274

Let me be even more precise, because now it seems like if i don't, it will be mass-broadcasted for humiliation purposes.

I have used L-ascorbic acid on my face, and since it's the original form, devoid of stabilizers that would make it hard to absorb, it absorbed in my skin pretty quickly and gave me a change in collagen in 15 minutes.

So, I recommend to just try it out. I expect that you will experience something similar.

 

[imontheloose]

Wanted to mention this point, but our lovely user @enchanted_elixir is most likely just baiting with his guides.

There is no way he recommends spearmint to decrease testosterone or free T to combat acne.

It's like buying a truck to transport a kitten instead of a transport box for cats.

The @truthhurts

@chadbeingmade

Trust me bro, high effort guides bro. I’m gatekeeping bro. Rub it on your face bro.

 

[imontheloose]

gave me a change in collagen in 15 minutes.

@chadbeingmade @Jonasㅤㅤ

 

[chadbeingmade]

it absorbed in my skin pretty quickly and gave me a change in collagen in 15 minutes

@enchanted_elixir after 15 minutes:

 

[imontheloose]

@enchanted_elixir after 15 minutes:
View attachment 3860288

This forum has never failed to bemuse me. Sounds like one of them 2013 YouTube videos.

 

[enchanted_elixir]

@enchanted_elixir after 15 minutes:
View attachment 3860288

Why don't you go try it out or research instead of just trolling me about it?

 

[Jonasㅤㅤ]

Trust me bro, high effort guides bro. I’m gatekeeping bro. Rub it on your face bro.

High effort low quality.

@enchanted_elixir after 15 minutes:
View attachment 3860288

Is the collagen synthesis in the room with us bro?

Edit: My apologies for that poor guy who was used for this edit back in 2024

@menas @loyolaxavvierretard @truthhurts @Eltrē @Toggle9877

 

[imontheloose]

Why don't you go try it out or research instead of just trolling me about it?

Synthetic variants of vitamin C have cool benefits. But not collagen production. You’re mistaking the brightening effects of it as being collagen, sir.

 

[imontheloose]

Is the collagen synthesis in the room with us bro?

I feel bad for OP. This nigga has been associated with every subhuman off r/roastme.

 

[chadbeingmade]

Why don't you go try it out or research instead of just trolling me about it?

You do understand that shiny skin or glass skin effect or brightening of skin =/= increased collagen, right?

 

[imontheloose]

You do understand that shiny skin or glass skin effect or brightening of skin =/= increased collagen, right?

Synthetic variants vitamin C have cool benefits. But not collagen production. You’re mistaking the brightening effects of it as being collagen, sir.

We really are Shanghai triplets.

 

[enchanted_elixir]

Synthetic variants vitamin C have cool benefits. But not collagen production. You’re mistaking the brightening effects of it as being collagen, sir.

I didn't use synthetic Vitamin C, where did you get that from?
I told you, I used L-ascorbic acid. The active form of Vitamin C.

 

[imontheloose]

I didn't use synthetic Vitamin C, where did you get that from?
I told you, I used L-ascorbic acid. The active form of Vitamin C.

Same thing applies no matter what variant of vitamin C you use.

 

[Toggle9877]

The Shanghai triplets stays undefeated

 

[imontheloose]

The Shanghai triplets stays undefeated

@chadbeingmade @Jonasㅤㅤ

 

[enchanted_elixir]

Same thing applies no matter what variant of vitamin C you use.

Alas, brother! faggot-ethyl-nigger-curry ascorbic acid phosphatase norduckerase also gives the "same thing"

 

[imontheloose]

Alas, brother! faggot-ethyl-nigger-curry ascorbic acid phosphatase norduckerase also gives the "same thing"

Believe it or not, the properties are almost identical. They merely try optimise it for absorption and sensitivity to light. Instead of frothing on your keyboard like an infantile retard, you should just admit you made some shit up and think bright skin = collagen.

 

[chadbeingmade]

@chadbeingmade @Jonasㅤㅤ

 

[imontheloose]

View attachment 3860302
View attachment 3860303

I would say you should make one of these for all the Shanghai triplet victims, but half of looksmaxxing questions would be in there.

 

[enchanted_elixir]

Same thing applies no matter what variant of vitamin C you use.

Evaluation of statement 1: "Brightening and collagen are mediated by different chains of causality" (paraphrase) -> Collagenated skin reflects more light, and vitamin C (l-ascorbic acid) serum is a serum that increases collagen production. The brightening effects are caused by the increase in collagen content in the skin.

Evaluation of statement 2: "Same thing applies no matter what variant of vitamin C you use." -> either you never took an undergraduate chemistry class (or textbook, or educational resource) or have a non-stellar IQ/forgot what you learned. Adding chemical groups to molecules change their nature and the effects they cause.

 

[enchanted_elixir]

Alas, brother! faggot-ethyl-nigger-curry ascorbic acid phosphatase norduckerase also gives the "same thing"

This comment is sarcasm.
The use of slurs are solely intended to exaggerate the sarcasm.

 

[enchanted_elixir]

Believe it or not, the properties are almost identical. They merely try optimise it for absorption and sensitivity to light. Instead of frothing on your keyboard like an infantile retard, you should just admit you made some shit up and think bright skin = collagen.

Let's terminate this chat, no need for a "winner".
I want to log out now. My brain is already rotting since my brief "Return"

 

[imontheloose]

Evaluation of statement 1: "Brightening and collagen are mediated by different chains of causality" (paraphrase) -> Collagenated skin reflects more light, and vitamin C (l-ascorbic acid) serum is a serum that increases collagen production. The brightening effects are caused by the increase in collagen content in the skin.

Evaluation of statement 2: "Same thing applies no matter what variant of vitamin C you use." -> either you never took an undergraduate chemistry class (or textbook, or educational resource) or have a non-stellar IQ/forgot what you learned. Adding chemical groups to molecules change their nature and the effects they cause.

Right listen here, nignog. Let me teach you some basics. Brightening of the skin’s main pathway is via melanin suppression. That’s literally the point of LAA. Firmer skin or plumper, however you wanna call it, is through the pathway of collagen I and III biosynthesis. Got it, niggy?

Light scattering from collagen is, no joke, totally negligible when you compare it to melanin dilution.

And you’re so fucking stupidly patronising when you’re quite literally wrong. I’ll show you exactly how it works with some derivatives, fag bag. MAP (phosphate ester), SAP (same shit, a Na+ salt), AG (glucose linked at C-2), AP (16-C fatty acid ester), etc.. Each of these essentially result in the same thing. I would bother explaining to you the mechanism of each, but there is not much point granted you lack the comprehension, so I’ll dumb it down.

Here’s a rule of thumb: Derivative (cutaneous enzymes) -> up goes LAA -> down goes melanin. Change the side-chain? You just change the solubility, penetrability, and perhaps shelf-life, not the fucking intracellular mechanism. If derivative X never liberates LAA (poor esterase activity for example), then brightening won’t happen. Simple. Chemically grafting ester/ether groups doesn’t change the ultimate mechanism. I feel like I’m teaching a special-ed child.

Your down syndrome, 5th percentile IQ, academic charlatan-self even stated you noticed collagen increase in 15 minutes, and I am the one miseducated in chemistry? Collagen takes months to build up. Your claim of 15 minutes is physiologically impossible. The observed radiance is melanin suppression and maybe some antioxidant reversal of oxidised chromophores not magical, instant neocollagenesis.

Fucking molested by a Shanghai soldier. PREPARE FOR DRILLING YOU UTTER SUBHUMAN!