Sayori
ascend or die
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Dosing's are for 400mg test c weekly
This will prob be my only and last androgen related guide, roids are cool and shii just boring and water
There is so much info out there already like mpmd YT channel
Table of contents:
This will prob be my only and last androgen related guide, roids are cool and shii just boring and water
There is so much info out there already like mpmd YT channel
Table of contents:
| DHT conversion |
| Collagen and elastin destruction |
| Oxidative stress |
| Shit Estrogen levels |
| Hematocrit |
| Bonus bust most effective anti aging compound |
Introduction:
First off, let's clarify that there is a distinction between aging and masculinization! Aging is skin thinning, hairline recession, leathery skin texture, puffiness, and loss of elasticity. While masculation is just how it sounds, getting a stronger jaw, definition, robustness, etc.
Mechanism of supraphysiological test aging:
Top 5:
- DHT conversion
- Collagen and elastin destruction
- Oxidative stress
- Shit Estrogen levels
- Hematocrit
Explanation of each aging mechanism from test:
DHT conversion
So testosterone converts to DHT ( dihydrotestrone ) through an enzyme named “ 5 alpha reductase”. DHT androgenic mogs test, it outcompetes it at the androgen receptors. DHT is responsible for your norwooding and shit skin. It will make your hair fall out and thin, your skin
will become coarse from it which means no more smooth mogger skin.
How to rape this useless compound named DHT:
For users on 400mg of test weekly or at least in a supraphysiological range, you should be taking at least 0.5 to 2.5 mg of dut daily!
Even .5 mg dut daily blocks out 94.7 % of type 1 and type 2 DHT, as shown in the study below where natties took .5mg daily. We will be taking 2.5 mg as we are not natties running natty dosages.
In this study below it shows natties raping 94.7& of their dht with .5 mg dut daily:
Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
Collagen and elastin destruction
How does our friend “testosterone” downregulate type 1 and type 3 collagen synthesis? Its pretty simple actually, Derma fibroblasts contain androgen receptors, now then when the androgens circulating through these receptors reach supraphysiological ranges it changes the gene expression through “transcription level down regulation”.
Listen, so supraphysiological levels of androgens bind to the androgen receptors within the dermal fibroblast, this causes downregulated transcription of the genes responsible for type 1 and 3 procollagen chains. In summer, less type 1 and 3 collagen in your skin because of this.
Now the second method in which high level of androgens suppress/shit on ur skin, they interfere with TGF-B which is a beta growth factor. Its the primary chemical that makes fibroblast build new extracellular matrix. The high levels of androgens blocks or dampens the signaling, lil note this makes it much easier to develop brootal scaring dude.
Now lastly, the two things above paired with fricking sun damage is even more brootal jfl, imagen having low uv protection and then the sun hits your skin and damages it. This then should lead to ur skin sending signals to repair this damage but guess what nga ur TGF-B is fried from high level androgens jfl. So its GG for ur skin!
Gen took me forever to generate a cool looking one, explaining this process (if only gpt wasnt jew, I had to resort to img generating on gemini err)
Must do to heavily prevent this:
- Ingest 2G of vitamin C daily
- Astaxanthin 12mg daily
- Glycine 10g Daily
- Accutane 10mg daily or trazodone/tretinoin (up to the highest level you can tolerate)
- SPF 50 or higher daily, every two fucking ours nga!!!
Oxidative stress
Now this is the little boy shit, it's easy to cover luckily
Supraphysocyclical androgen levels increase ROS (reactive oxygen species) production systemically. ROS rapes cellular membranes, mitochondrial dna, and the extracellular matrix. This will zap the life out ur skin G. It also just ages u over all, literally makes u older faster dude.
I'm not going to go deep into the mechanism here since there are many and im tired asf rn, its 2:50 am rn here in cali. Just imagine the more ROS = uglier and older.
Ight ngas its a different day, I didnt sleep for shii but im still trying to make this shit for u little grey’s. If this shit was made before I finish it im roping nga, I literally stayed up reading for this fuck ass shit!!!
Evil and bad things that high androgens cause, oxidative stress version:
- Mitochondrial Electron transport chain dysfunction and electron leakage
- Free radical induced lipid peroxidation of polyunsaturated fatty acids
- Oxidative mutagenesis of mitochondrial DNA (mtDNA)
Mitochondrial Electron transport chain dysfunction and electron leakage:
“During mitochondrial respiration, a small fraction of oxygen can be converted to superoxide due to electron leakage from the electron transport chain. However, the extent of superoxide generation is highly dependent on the metabolic state, substrates utilized, oxygen availability “ did you reed that nga this is showing that during mitochondrial respiration “superoxide” is created. But guess what G, supraphysiological levels of test force this process into overdrive, thus creating so much fucking Superoxide which is a type of ROS. This wouldn't be bad if your body didn't get overwhelmed by the sheer amount and it all starts converiting into Hydroxyl radicals (OH). These radicals target anything so it damages and mutates shit in ur body. I mean anything nga, these little fucks will cook you so hard so watch out. This all leads to a domino effect, everything falls bruh so follow to the tea what I instruct below.
If you want to find this for yourself here is the link and a helpful screen shot:
Full article: Mitochondrial antioxidant enzyme (SOD2) at the crossroads of redox signaling and cancer progression
There is more shit but im bored and I know you grey ngas aint read all ts yap, jfl
What to take:
- NAC 1200mg daily + glutathione IM 400 mg 3x weekly
- R ALA 600 mg daily
- CoQ10 ubiquinol 400mg daily
- Vitamin C, and astaxanthin with all this shii together ( but you should be taking it already as I mentioned taking this above)
Shit Estrogen levels
- Pin daily jfl and you'll be good
Lil info:
Estrogen keeps our skin hydrated, thick, and collagen levels up so you don't want it low. That does not mean you want it high tho as you will retain too much water, or even get gyno lolers. Low E2 will make you look dry, weird, thin skin. Basically not a robust pretty boy or pretty boy at all.
Hematocrit
Your blood sends oxygen to everything so imagine having shit blood that doesn't send much oxygen. Ur gonna feel like shit and look like you feel + if this goes bad it will kill you G.
We all want that little reddish glow that oxygenated blood gives us
Num 1 thing you can do for this:
Drink over 4 liters of water daily, this is the most effective method. No! Blood donation will not save you faggot, drink ur fucking water pussy
Anyways take your tadalafil as well 10 mg for a dosage of 400mg test c weekly and your fish oils
What to take:
Above 4 L water daily ( nothing will beat this ever)
Tadalafil 10mg daily
Fish oil epa/dha 5000 mg daily
Bonus bust most effective anti aging compound
Its called rapamycin, ik sadist or sum shit made a thread about it. Anyways take at least 5 mg of that weekly minimum.
I give up on this thread, idc for it ! search up what this shit does for urself
I am not writing the list of the protocol together, at least read the thread
tldr:
@AgentAngularity is a cuck
Tags:
@goku21 @Starborn @illusion @Diyorldar @coolman985
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and dht blockers if you’re past puberty
