Looksmax.meOg2019
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FGFR3 Inhibitor effects on muscle and how we ———————can fix this issue———————
FGFR3 underactivation leads to decreased PISK Akt signaling
This results in lower mTOR and higher atrogin1 and MuRF1
less mtor and higher
atrogin1+MuRF1-less muscle hypertrophy, more catabolism, worse muscle quality, induced weakness
so what do we do to not have shit muscles on fgfr3i?
literally the easiest thing to prevent xD
So in summary Just pin roid and GH
FGFR3 underactivation leads to decreased PISK Akt signaling
This results in lower mTOR and higher atrogin1 and MuRF1
less mtor and higher
atrogin1+MuRF1-less muscle hypertrophy, more catabolism, worse muscle quality, induced weakness
so what do we do to not have shit muscles on fgfr3i?
literally the easiest thing to prevent xD
- Androgens (increase mTOR and decrease overall catabolism)
- Insulin
- IGF-1 gained from HGH
So in summary Just pin roid and GH
