How to use peptides- CJC , GHK-cu and more- the truth about peptides

Aryan Incel

Aryan Incel

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In the recent times peptides have gained a lot of popularity/ attention for their uses and how they could become a more natural alternative to things like roids and HGH. In this thread I will discuss the most popular and useful peptides and whether they should be used.

IMG 7607


a peptide is a short chain of 2 to about 100 amino acids linked together by peptide bonds, acting as fundamental building blocks for proteins and carrying out various cellular functions, from signaling to providing structural support

It stimulates the pigment cells in your skin to produce more melanin, and this makes the skin look darker. This process also makes you more uv protective over time



IMG_7595.jpeg
Facial Flushing


DermNethttps://dermnetnz.orgMelanotan II


Appetite Suppression

This is a rare side effect and shouldn't be relied upon for this effect and you should use proper appetite suppresses like glp-1 antagonists


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govActivation of the central melanocortin system chronically reduces body ...


Darkening Of Moles & Freckles

you should keep watch over any old or new moles to check if they change in shape or colour, if they do, get them checked by a healthcare professional. This is the most dangerously side effect


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govChanges of melanocytic lesions inducedby Melanotan injections ...


Lethargy, Nausea and Dizziness


Healthlinehttps://www.healthline.comTanning Nasal Spray: Should You Skip It?
For injection


For doses of less than 500mcg it would be best to use 2ml of water.

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 syringe

1 alcohol swab


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper. Wipe with the swab.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw your water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves, you can swirl or tilt the vial to help.


For Nasal

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 empty nasal spray bottle or 1 OTC nasal mist

1 syringe


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw 50 units of water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves,

6. Insert the syringe again and turn upside down.

7. Withdraw all of the liquid and remove the syringe.

8. Unscrew the cap of your nasal spray and slowly inject the liquid into the bottle.

9. If using an empty bottle you can now transfer the remainder of the water. Wait 2 hours before use.
When in freeze dried form they can be stored in many ways;

Room temperature – 12 months
Refrigerated – 48 months

Freezer – 48 months+


When reconstituted with sodium chloride it can be stored either;

Refrigerated – 1 month

Freezer – 48 months


When reconstituted with bacteriostatic water it should be stored;

Room temperature – 2 months

Refrigerated – 48 months
Melanotan 2 has a half life of ~33 hours, this allows you to be very flexible with dosing. However, it will always be better to inject in the morning or midday if getting natural UV exposure. If you are using sunbeds then inject about 20 minutes before exposure.


Recommended dosages start at 250mcg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 500mcg and stick at this point.


You can increase the dose as far as about 1mg but it is generally not advised - any higher and you'll be overdosing.
Once you have reached your desired level of tan then you can enter what is known as the 'maintenance phase'.


Although the level is different for most people it levels out at around 500mcg every 3 or 4 days and a sunbed session with every or every other dose.


This will allow you to maintain your tan through winter without much work.


If you notice at any point you're becoming darker, reduce the dose.


If you notice you are getting lighter, add in an extra dose or take up the second sunbed session if you didn't already.
MT2 is very useful for getting a tan and should be used as it has few drawbacks. However if you’re ethnic it should not be used under any circumstances as darker skin will failo

It works by binding with copper ions, acting as a naturally occurring human signaling peptide that promotes cell repair, regeneration, and tissue remodeling.

IMG_7596.jpeg
Effective in removing acne scars

https://www.researchgate.net/public...ns (3)-,References (29),group, respectively. ...


Anti aging

https://en.wikipedia.org/wiki/Coppe...y used in anti-aging,of copper peptide GHK-Cu.


Collagen

https://pmc.ncbi.nlm.nih.gov/articl...histidyl,disease, and metastatic colon cancer.


While GHK-Cu is not a direct DHT blocker like Dutasteride, some research suggests that it may promote follicular resilience, reducing the negative impact of DHT on hair growth

https://tressless.com/learn/ghk-cu/what-is-ghk-cu-and-why-is-it-said-to-be-a-miracle-for-hair-1rqkj


Great for muscle/ tissue repair. So great for recovery post surgery.


https://www.liebertpub.com/doi/10.1...,this compound affects irradiated fibroblasts.
Less bioavailable than the other two forms of GHK cu

https://pmc.ncbi.nlm.nih.gov/articl...ly or orally when encapsulated into liposomes.


Less effective dues to the worse bioavailability


Anecdotally more some people have seen some like nausea, liver damage and fatigue
Directly targets the skin

https://pmc.ncbi.nlm.nih.gov/articl...r of clinical studies,aged skin, Krüger et al.


And proven to improve collagen

National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govRegenerative and Protective Actions of the GHK-Cu Peptide in the Light ...


However the amount absorbed by the skin is debatable and definitely not as effective as injectable GHK cu but could be used as well as injectable GHK cu
It has all the benefits I listed above in the benefit section


IMPORTANT
For best results inject it in your face. probably cheeks, jaw or scalp are best
Use around 3ml (300 units) of water per 50 mg of GHK cu


First, gather your supplies;

1 vial of GHK cu (50 mg)

1 vial/ampule of water (use bacteriostatic if you’re only concerned with collagen/ skin but use Phosphate Buffered Saline if you want all the benefits)

1 syringe

1 alcohol swab


1. Take your GHK cu vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.Draw 3.0 mL of bacteriostatic water/ Phosphate Buffered Saline into a sterile syringe.

3.Inject the water slowly along the vial wall to reduce foaming.

4.Gently swirl the vial—avoid vigorous shaking.

5.Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
When in freeze dried form it can be stored in many ways;

Refrigerated (has to be below 4 C) – 24 months

Freezer – 36 months


When reconstituted with Phosphate Buffered Saline it can be stored either;

Refrigerated - 1-8 weeks

Freezer – 3 to 12 months


When reconstituted with bacteriostatic water it should be stored;

Refrigerated – 6-8 weeks

Freezer- 6-12 months
GHK cu has a half life of ~2 hours, means you’re less flexible with dosing. It’s for this reason best to inject twice a day, once in the morning and again at night. For example 2.5 mg in the morning and 2.5 mg at night.


Recommended dosages start at 1-2.5 mg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 5 mg and stick at this point.

You can increase the dose as far as about 10 mg but it is generally not advised - any higher and you'll be get barely any extra benefits.
Once you have reached what you find to be a ideal dose for GHK cu you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
GHK cu is a very good peptide which everyone should be injecting.


Taking topical as well could improve collagen even more but it has been proven and is up for debate.


Oral shouldn’t be used under any circumstance.

These peptides increase certain hormones like igf1 and HGH. However the effects are less powerful/ significant than just using HGH.


This study shows HGH increases by 46% using CJC

https://pubmed.ncbi.nlm.nih.gov/163...estimated half-life of CJC-1295 was 5.8-8.1 d.


This would be equivalent of going from 1 IU per day (this is what your body produces naturally) to 1.5 IU at the upper end


Compare this to how you could just inject HGH which will give much better results (4 IU +)


The reason that peptides will never be able to complete with something like HGH is because they it has a cap on how much you can improve which is because of your body.


In addition peptides are the same cost as roid/ gh something like HGH costs $2-$3 per day ($0.5 per 1 IU) compared to $1.75 per day ($80 per vial of 5 mg) with a CJC and ipamorelin blend


To conclude you should not use any peptides for muscle growth because they will give you worse results and just as expensive as something like HGH

It works by binding directly to the androgen receptors in the skin and hair and BLOCKS them so that no other androgen can bind. In this way, it can block both testosterone and DHT from damaging hair.

IMG_7608.jpeg
Stops androgen binding to your hair follicles

Harley Street Hair Transplant Clinicshttps://www.harleystreethairtransplant.co.ukRU58841 For Hair Loss - A New Finasteride Alternative?


Could potentially stop synthetic androgen from binding to your hair like tren

https://pubmed.ncbi.nlm.nih.gov/979...t that,, androgenetic alopecia, and hirsutism.


99% gets broken down instantly into inert molecules with no effect on the body. Only 1% of the breakdown product acts as a systemic anti-androgen.
First, gather your supplies;

Dipropylene glycol

95% ethanol

Azelaic acid

A jewelery scale

RU58841 powder

Minoxodil powder

100 mL tinted glass bottles

1-2 mL eye dropper

Smidgen measuring spoon

Mini funnel

alcohol swab


1)The first step is to mix up some the solvent. You can do this approximately. It doesn't have to be perfect. Pour 20 mL of dipropylene glycol into the mini measure shot glass. Pour this into your 100 mL tinted glass bottle (using the funnel). Then measure 30 mL of ethanol in the shot glass, and also pour this into your 100 mL tinted bottle. You now have 50 mL of 60/40 ethanol/dipropylene-glycol solution. If you want more, repeat this process once more into the same bottle and you have 100 mL which will last almost 2 months.

2)Use your pipette and draw up ~2 mL of the 60/40 solvent. Put it in the shot glass. You will be mixing your day’s application in this shot glass in this way each day.

3)A dose of 100 mg RU58841 daily works best. You can go as low as 50 mg if you're lucky. Or as high as 150 mg whatever works best. Use 2 flat smidgens of RU58841 which works out to almost exactly 100 mg.

4)do the same with the minox

5)and azelaic acid

6)Dump all those flat smidgen scoops of your powders into the shot glass containing 2 mL solvent.

7)Swirl it to mix. Letting it sit 5-10 minutes often helps.

8)Next once it is fully mixed, use the dropper to draw up ~0.25 mL of solution at a time and apply to scalp, one area at a time. Rub it in each time to spread it around. You’ll want to make sure you especially get the frontal hairline, temples, corners, and crown. 2 mL is just enough to get a good coverage. If you want to be sure you are covering well enough, 2.5 mL is good too.
When in powder form it can be stored in many ways;

Room temp -2 years

Refrigerated – almost indefinitely

Freezer – almost indefinitely
RU 58841 has a half life of ~1 hours, when used orally in mice, however no data has been done for topical use but we could estimate it would last around 12-24 hours means you’re flexible with dosing. It’s for this reason best to use once a day.

Recommended dosages start at use between 50-150 mg daily
Once you have reached what you find to be a ideal dose for RU you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
RU 58841 should be used by everyone especially if you are dealing with hair loss.


With isnt only negative being how tedious it is to make.


However the benefits and potential shows it could potentially mog something like Dutasteride

Most of the information came from @Sadist and @Copercel threads so credit to them for this section


Epitalon enhances telomerase activity, which protects telomeres from shortening during cell division.

IMG_7598.jpeg
Use around 1 ml of BAC to a 10 mg vial


First, gather your supplies;

1 vial of epitalon (10mg)

1 vial/ampule of water

1 syringe

1 alcohol swab


1)Clean everything with alcohol pads: vial tops, your hands, etc.

2)Draw up 1-2 mL of bacteriostatic waterusing a sterile syringe.

3)Slowly inject the water into the Epitalonvial (aim against the glass wall to avoid foaming).

4)Let the powder dissolve gently, do not shake. Swirl lightly if needed.

5)Store the reconstituted vial in the fridge
When in freeze dried form;

Room temp- 3 weeks

Refrigerated – 48 months+

Freezer – 48 months+


When reconstituted;

Refrigerated - 20-30 days

Freezer – 3 to 12 months
Epitalon should be injected twice a day, once in the morning and again at night. You should take 5 mg a day and should be cycled for 20 days every 3 months for best results
Do it once every 3 months and you should be good. If you don’t like the 20 day 5 mg cycle you could always switch to a 10 mg 10 day cycle but whatever works for you
No question everyone should be cycling Epitalon. If you consider yourself a looksmaxxer and don’t cycle Epitalon from now on you’re doing yourself a disservice.

@FlotPSL @Zagro @MaracasMogs
 
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In the recent times peptides have gained a lot of popularity/ attention for their uses and how they could become a more natural alternative to things like roids and HGH. In this thread I will discuss the most popular and useful peptides and whether they should be used.


a peptide is a short chain of 2 to about 100 amino acids linked together by peptide bonds, acting as fundamental building blocks for proteins and carrying out various cellular functions, from signaling to providing structural support

It stimulates the pigment cells in your skin to produce more melanin, and this makes the skin look darker. This process also makes you more uv protective over time



View attachment 4135577
Facial Flushing


DermNethttps://dermnetnz.orgMelanotan II


Appetite Suppression

This is a rare side effect and shouldn't be relied upon for this effect and you should use proper appetite suppresses like glp-1 antagonists


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govActivation of the central melanocortin system chronically reduces body ...


Darkening Of Moles & Freckles

you should keep watch over any old or new moles to check if they change in shape or colour, if they do, get them checked by a healthcare professional. This is the most dangerously side effect


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govChanges of melanocytic lesions inducedby Melanotan injections ...


Lethargy, Nausea and Dizziness


Healthlinehttps://www.healthline.comTanning Nasal Spray: Should You Skip It?
For injection


For doses of less than 500mcg it would be best to use 2ml of water.

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 syringe

1 alcohol swab


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper. Wipe with the swab.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw your water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves, you can swirl or tilt the vial to help.


For Nasal

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 empty nasal spray bottle or 1 OTC nasal mist

1 syringe


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw 50 units of water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves,

6. Insert the syringe again and turn upside down.

7. Withdraw all of the liquid and remove the syringe.

8. Unscrew the cap of your nasal spray and slowly inject the liquid into the bottle.

9. If using an empty bottle you can now transfer the remainder of the water. Wait 2 hours before use.
When in freeze dried form they can be stored in many ways;

Room temperature – 12 months
Refrigerated – 48 months

Freezer – 48 months+


When reconstituted with sodium chloride it can be stored either;

Refrigerated – 1 month

Freezer – 48 months


When reconstituted with bacteriostatic water it should be stored;

Room temperature – 2 months

Refrigerated – 48 months
Melanotan 2 has a half life of ~33 hours, this allows you to be very flexible with dosing. However, it will always be better to inject in the morning or midday if getting natural UV exposure. If you are using sunbeds then inject about 20 minutes before exposure.


Recommended dosages start at 250mcg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 500mcg and stick at this point.


You can increase the dose as far as about 1mg but it is generally not advised - any higher and you'll be overdosing.
Once you have reached your desired level of tan then you can enter what is known as the 'maintenance phase'.


Although the level is different for most people it levels out at around 500mcg every 3 or 4 days and a sunbed session with every or every other dose.


This will allow you to maintain your tan through winter without much work.


If you notice at any point you're becoming darker, reduce the dose.


If you notice you are getting lighter, add in an extra dose or take up the second sunbed session if you didn't already.
MT2 is very useful for getting a tan and should be used as it has few drawbacks. However if you’re ethnic it should not be used under any circumstances as darker skin will failo

It works by binding with copper ions, acting as a naturally occurring human signaling peptide that promotes cell repair, regeneration, and tissue remodeling.

View attachment 4135623
Less bioavailable than the other two forms of GHK cu

https://pmc.ncbi.nlm.nih.gov/articles/PMC3359723/#:~:text=Therapeutic Administration of GHK-Cu&text=The peptide could be administered intravenously or orally when encapsulated into liposomes.


Less effective dues to the worse bioavailability


Anecdotally more some people have seen some like nausea, liver damage and fatigue
Directly targets the skin

https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/#:~:text=A number of clinical studies,aged skin, Krüger et al.


And proven to improve collagen

National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govRegenerative and Protective Actions of the GHK-Cu Peptide in the Light ...


However the amount absorbed by the skin is debatable and definitely not as effective as injectable GHK cu but could be used as well as injectable GHK cu
It has all the benefits I listed above in the benefit section


IMPORTANT
For best results inject it in your face. probably cheeks, jaw or scalp are best
Use around 3ml (300 units) of water per 50 mg of GHK cu


First, gather your supplies;

1 vial of GHK cu (50 mg)

1 vial/ampule of water (use bacteriostatic if you’re only concerned with collagen/ skin but use Phosphate Buffered Saline if you want all the benefits)

1 syringe

1 alcohol swab


1. Take your GHK cu vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.Draw 3.0 mL of bacteriostatic water/ Phosphate Buffered Saline into a sterile syringe.

3.Inject the water slowly along the vial wall to reduce foaming.

4.Gently swirl the vial—avoid vigorous shaking.

5.Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
When in freeze dried form it can be stored in many ways;

Refrigerated (has to be below 4 C) – 24 months

Freezer – 36 months


When reconstituted with Phosphate Buffered Saline it can be stored either;

Refrigerated - 1-8 weeks

Freezer – 3 to 12 months


When reconstituted with bacteriostatic water it should be stored;

Refrigerated – 6-8 weeks

Freezer- 6-12 months
GHK cu has a half life of ~2 hours, means you’re less flexible with dosing. It’s for this reason best to inject twice a day, once in the morning and again at night. For example 2.5 mg in the morning and 2.5 mg at night.


Recommended dosages start at 1-2.5 mg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 5 mg and stick at this point.

You can increase the dose as far as about 10 mg but it is generally not advised - any higher and you'll be get barely any extra benefits.
Once you have reached what you find to be a ideal dose for GHK cu you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
GHK cu is a very good peptide which everyone should be injecting.


Taking topical as well could improve collagen even more but it has been proven and is up for debate.


Oral shouldn’t be used under any circumstance.

These peptides increase certain hormones like igf1 and HGH. However the effects are less powerful/ significant than just using HGH.


This study shows HGH increases by 46% using CJC

https://pubmed.ncbi.nlm.nih.gov/16352683/#:~:text=Results: After a single injection of CJC-1295,,estimated half-life of CJC-1295 was 5.8-8.1 d.


This would be equivalent of going from 1 IU per day (this is what your body produces naturally) to 1.5 IU at the upper end


Compare this to how you could just inject HGH which will give much better results (4 IU +)


The reason that peptides will never be able to complete with something like HGH is because they it has a cap on how much you can improve which is because of your body.


In addition peptides are the same cost as roid/ gh something like HGH costs $2-$3 per day ($0.5 per 1 IU) compared to $1.75 per day ($80 per vial of 5 mg) with a CJC and ipamorelin blend


To conclude you should not use any peptides for muscle growth because they will give you worse results and just as expensive as something like HGH

It works by binding directly to the androgen receptors in the skin and hair and BLOCKS them so that no other androgen can bind. In this way, it can block both testosterone and DHT from damaging hair.

View attachment 4136325
Stops androgen binding to your hair follicles

Harley Street Hair Transplant Clinicshttps://www.harleystreethairtransplant.co.ukRU58841 For Hair Loss - A New Finasteride Alternative?


Could potentially stop synthetic androgen from binding to your hair like tren

https://pubmed.ncbi.nlm.nih.gov/9798729/#:~:text=Together our results suggest that,, androgenetic alopecia, and hirsutism.


99% gets broken down instantly into inert molecules with no effect on the body. Only 1% of the breakdown product acts as a systemic anti-androgen.
First, gather your supplies;

Dipropylene glycol

95% ethanol

Azelaic acid

A jewelery scale

RU58841 powder

Minoxodil powder

100 mL tinted glass bottles

1-2 mL eye dropper

Smidgen measuring spoon

Mini funnel

alcohol swab


1)The first step is to mix up some the solvent. You can do this approximately. It doesn't have to be perfect. Pour 20 mL of dipropylene glycol into the mini measure shot glass. Pour this into your 100 mL tinted glass bottle (using the funnel). Then measure 30 mL of ethanol in the shot glass, and also pour this into your 100 mL tinted bottle. You now have 50 mL of 60/40 ethanol/dipropylene-glycol solution. If you want more, repeat this process once more into the same bottle and you have 100 mL which will last almost 2 months.

2)Use your pipette and draw up ~2 mL of the 60/40 solvent. Put it in the shot glass. You will be mixing your day’s application in this shot glass in this way each day.

3)A dose of 100 mg RU58841 daily works best. You can go as low as 50 mg if you're lucky. Or as high as 150 mg whatever works best. Use 2 flat smidgens of RU58841 which works out to almost exactly 100 mg.

4)do the same with the minox

5)and azelaic acid

6)Dump all those flat smidgen scoops of your powders into the shot glass containing 2 mL solvent.

7)Swirl it to mix. Letting it sit 5-10 minutes often helps.

8)Next once it is fully mixed, use the dropper to draw up ~0.25 mL of solution at a time and apply to scalp, one area at a time. Rub it in each time to spread it around. You’ll want to make sure you especially get the frontal hairline, temples, corners, and crown. 2 mL is just enough to get a good coverage. If you want to be sure you are covering well enough, 2.5 mL is good too.
When in powder form it can be stored in many ways;

Room temp -2 years

Refrigerated – almost indefinitely

Freezer – almost indefinitely
RU 58841 has a half life of ~1 hours, when used orally in mice, however no data has been done for topical use but we could estimate it would last around 12-24 hours means you’re flexible with dosing. It’s for this reason best to use once a day.

Recommended dosages start at use between 50-150 mg daily
Once you have reached what you find to be a ideal dose for RU you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
RU 58841 should be used by everyone especially if you are dealing with hair loss.


With isnt only negative being how tedious it is to make.


However the benefits and potential shows it could potentially mog something like Dutasteride

Most of the information came from @Sadist and @Copercel threads so credit to them for this section


Epitalon enhances telomerase activity, which protects telomeres from shortening during cell division.

View attachment 4136336
Use around 1 ml of BAC to a 10 mg vial


First, gather your supplies;

1 vial of epitalon (10mg)

1 vial/ampule of water

1 syringe

1 alcohol swab


1)Clean everything with alcohol pads: vial tops, your hands, etc.

2)Draw up 1-2 mL of bacteriostatic waterusing a sterile syringe.

3)Slowly inject the water into the Epitalonvial (aim against the glass wall to avoid foaming).

4)Let the powder dissolve gently, do not shake. Swirl lightly if needed.

5)Store the reconstituted vial in the fridge
When in freeze dried form;

Room temp- 3 weeks

Refrigerated – 48 months+

Freezer – 48 months+


When reconstituted;

Refrigerated - 20-30 days

Freezer – 3 to 12 months
Epitalon should be injected twice a day, once in the morning and again at night. You should take 5 mg a day and should be cycled for 20 days every 3 months for best results
Do it once every 3 months and you should be good. If you don’t like the 20 day 5 mg cycle you could always switch to a 10 mg 10 day cycle but whatever works for you
No question everyone should be cycling Epitalon. If you consider yourself a looksmaxxer and don’t cycle Epitalon from now on you’re doing yourself a disservice.

@FlotPSL @Zagro @MaracasMogs
high effort thread :feelsyay:
 
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tagging a couple more people (don’t ban me pls mods :feelswah:) @chadisbeingmade @Stacyslayerᛉ @SlayerJonas @iblamegenetics7681
 
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Reactions: Zagro, Stacyslayerᛉ and BigBallsLarry
In the recent times peptides have gained a lot of popularity/ attention for their uses and how they could become a more natural alternative to things like roids and HGH. In this thread I will discuss the most popular and useful peptides and whether they should be used.


a peptide is a short chain of 2 to about 100 amino acids linked together by peptide bonds, acting as fundamental building blocks for proteins and carrying out various cellular functions, from signaling to providing structural support

It stimulates the pigment cells in your skin to produce more melanin, and this makes the skin look darker. This process also makes you more uv protective over time



View attachment 4135577
Facial Flushing


DermNethttps://dermnetnz.orgMelanotan II


Appetite Suppression

This is a rare side effect and shouldn't be relied upon for this effect and you should use proper appetite suppresses like glp-1 antagonists


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govActivation of the central melanocortin system chronically reduces body ...


Darkening Of Moles & Freckles

you should keep watch over any old or new moles to check if they change in shape or colour, if they do, get them checked by a healthcare professional. This is the most dangerously side effect


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govChanges of melanocytic lesions inducedby Melanotan injections ...


Lethargy, Nausea and Dizziness


Healthlinehttps://www.healthline.comTanning Nasal Spray: Should You Skip It?
For injection


For doses of less than 500mcg it would be best to use 2ml of water.

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 syringe

1 alcohol swab


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper. Wipe with the swab.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw your water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves, you can swirl or tilt the vial to help.


For Nasal

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 empty nasal spray bottle or 1 OTC nasal mist

1 syringe


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw 50 units of water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves,

6. Insert the syringe again and turn upside down.

7. Withdraw all of the liquid and remove the syringe.

8. Unscrew the cap of your nasal spray and slowly inject the liquid into the bottle.

9. If using an empty bottle you can now transfer the remainder of the water. Wait 2 hours before use.
When in freeze dried form they can be stored in many ways;

Room temperature – 12 months
Refrigerated – 48 months

Freezer – 48 months+


When reconstituted with sodium chloride it can be stored either;

Refrigerated – 1 month

Freezer – 48 months


When reconstituted with bacteriostatic water it should be stored;

Room temperature – 2 months

Refrigerated – 48 months
Melanotan 2 has a half life of ~33 hours, this allows you to be very flexible with dosing. However, it will always be better to inject in the morning or midday if getting natural UV exposure. If you are using sunbeds then inject about 20 minutes before exposure.


Recommended dosages start at 250mcg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 500mcg and stick at this point.


You can increase the dose as far as about 1mg but it is generally not advised - any higher and you'll be overdosing.
Once you have reached your desired level of tan then you can enter what is known as the 'maintenance phase'.


Although the level is different for most people it levels out at around 500mcg every 3 or 4 days and a sunbed session with every or every other dose.


This will allow you to maintain your tan through winter without much work.


If you notice at any point you're becoming darker, reduce the dose.


If you notice you are getting lighter, add in an extra dose or take up the second sunbed session if you didn't already.
MT2 is very useful for getting a tan and should be used as it has few drawbacks. However if you’re ethnic it should not be used under any circumstances as darker skin will failo

It works by binding with copper ions, acting as a naturally occurring human signaling peptide that promotes cell repair, regeneration, and tissue remodeling.

View attachment 4135623
Less bioavailable than the other two forms of GHK cu

https://pmc.ncbi.nlm.nih.gov/articles/PMC3359723/#:~:text=Therapeutic Administration of GHK-Cu&text=The peptide could be administered intravenously or orally when encapsulated into liposomes.


Less effective dues to the worse bioavailability


Anecdotally more some people have seen some like nausea, liver damage and fatigue
Directly targets the skin

https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/#:~:text=A number of clinical studies,aged skin, Krüger et al.


And proven to improve collagen

National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govRegenerative and Protective Actions of the GHK-Cu Peptide in the Light ...


However the amount absorbed by the skin is debatable and definitely not as effective as injectable GHK cu but could be used as well as injectable GHK cu
It has all the benefits I listed above in the benefit section


IMPORTANT
For best results inject it in your face. probably cheeks, jaw or scalp are best
Use around 3ml (300 units) of water per 50 mg of GHK cu


First, gather your supplies;

1 vial of GHK cu (50 mg)

1 vial/ampule of water (use bacteriostatic if you’re only concerned with collagen/ skin but use Phosphate Buffered Saline if you want all the benefits)

1 syringe

1 alcohol swab


1. Take your GHK cu vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.Draw 3.0 mL of bacteriostatic water/ Phosphate Buffered Saline into a sterile syringe.

3.Inject the water slowly along the vial wall to reduce foaming.

4.Gently swirl the vial—avoid vigorous shaking.

5.Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
When in freeze dried form it can be stored in many ways;

Refrigerated (has to be below 4 C) – 24 months

Freezer – 36 months


When reconstituted with Phosphate Buffered Saline it can be stored either;

Refrigerated - 1-8 weeks

Freezer – 3 to 12 months


When reconstituted with bacteriostatic water it should be stored;

Refrigerated – 6-8 weeks

Freezer- 6-12 months
GHK cu has a half life of ~2 hours, means you’re less flexible with dosing. It’s for this reason best to inject twice a day, once in the morning and again at night. For example 2.5 mg in the morning and 2.5 mg at night.


Recommended dosages start at 1-2.5 mg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 5 mg and stick at this point.

You can increase the dose as far as about 10 mg but it is generally not advised - any higher and you'll be get barely any extra benefits.
Once you have reached what you find to be a ideal dose for GHK cu you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
GHK cu is a very good peptide which everyone should be injecting.


Taking topical as well could improve collagen even more but it has been proven and is up for debate.


Oral shouldn’t be used under any circumstance.

These peptides increase certain hormones like igf1 and HGH. However the effects are less powerful/ significant than just using HGH.


This study shows HGH increases by 46% using CJC

https://pubmed.ncbi.nlm.nih.gov/16352683/#:~:text=Results: After a single injection of CJC-1295,,estimated half-life of CJC-1295 was 5.8-8.1 d.


This would be equivalent of going from 1 IU per day (this is what your body produces naturally) to 1.5 IU at the upper end


Compare this to how you could just inject HGH which will give much better results (4 IU +)


The reason that peptides will never be able to complete with something like HGH is because they it has a cap on how much you can improve which is because of your body.


In addition peptides are the same cost as roid/ gh something like HGH costs $2-$3 per day ($0.5 per 1 IU) compared to $1.75 per day ($80 per vial of 5 mg) with a CJC and ipamorelin blend


To conclude you should not use any peptides for muscle growth because they will give you worse results and just as expensive as something like HGH

It works by binding directly to the androgen receptors in the skin and hair and BLOCKS them so that no other androgen can bind. In this way, it can block both testosterone and DHT from damaging hair.

View attachment 4136325
Stops androgen binding to your hair follicles

Harley Street Hair Transplant Clinicshttps://www.harleystreethairtransplant.co.ukRU58841 For Hair Loss - A New Finasteride Alternative?


Could potentially stop synthetic androgen from binding to your hair like tren

https://pubmed.ncbi.nlm.nih.gov/9798729/#:~:text=Together our results suggest that,, androgenetic alopecia, and hirsutism.


99% gets broken down instantly into inert molecules with no effect on the body. Only 1% of the breakdown product acts as a systemic anti-androgen.
First, gather your supplies;

Dipropylene glycol

95% ethanol

Azelaic acid

A jewelery scale

RU58841 powder

Minoxodil powder

100 mL tinted glass bottles

1-2 mL eye dropper

Smidgen measuring spoon

Mini funnel

alcohol swab


1)The first step is to mix up some the solvent. You can do this approximately. It doesn't have to be perfect. Pour 20 mL of dipropylene glycol into the mini measure shot glass. Pour this into your 100 mL tinted glass bottle (using the funnel). Then measure 30 mL of ethanol in the shot glass, and also pour this into your 100 mL tinted bottle. You now have 50 mL of 60/40 ethanol/dipropylene-glycol solution. If you want more, repeat this process once more into the same bottle and you have 100 mL which will last almost 2 months.

2)Use your pipette and draw up ~2 mL of the 60/40 solvent. Put it in the shot glass. You will be mixing your day’s application in this shot glass in this way each day.

3)A dose of 100 mg RU58841 daily works best. You can go as low as 50 mg if you're lucky. Or as high as 150 mg whatever works best. Use 2 flat smidgens of RU58841 which works out to almost exactly 100 mg.

4)do the same with the minox

5)and azelaic acid

6)Dump all those flat smidgen scoops of your powders into the shot glass containing 2 mL solvent.

7)Swirl it to mix. Letting it sit 5-10 minutes often helps.

8)Next once it is fully mixed, use the dropper to draw up ~0.25 mL of solution at a time and apply to scalp, one area at a time. Rub it in each time to spread it around. You’ll want to make sure you especially get the frontal hairline, temples, corners, and crown. 2 mL is just enough to get a good coverage. If you want to be sure you are covering well enough, 2.5 mL is good too.
When in powder form it can be stored in many ways;

Room temp -2 years

Refrigerated – almost indefinitely

Freezer – almost indefinitely
RU 58841 has a half life of ~1 hours, when used orally in mice, however no data has been done for topical use but we could estimate it would last around 12-24 hours means you’re flexible with dosing. It’s for this reason best to use once a day.

Recommended dosages start at use between 50-150 mg daily
Once you have reached what you find to be a ideal dose for RU you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
RU 58841 should be used by everyone especially if you are dealing with hair loss.


With isnt only negative being how tedious it is to make.


However the benefits and potential shows it could potentially mog something like Dutasteride

Most of the information came from @Sadist and @Copercel threads so credit to them for this section


Epitalon enhances telomerase activity, which protects telomeres from shortening during cell division.

View attachment 4136336
Use around 1 ml of BAC to a 10 mg vial


First, gather your supplies;

1 vial of epitalon (10mg)

1 vial/ampule of water

1 syringe

1 alcohol swab


1)Clean everything with alcohol pads: vial tops, your hands, etc.

2)Draw up 1-2 mL of bacteriostatic waterusing a sterile syringe.

3)Slowly inject the water into the Epitalonvial (aim against the glass wall to avoid foaming).

4)Let the powder dissolve gently, do not shake. Swirl lightly if needed.

5)Store the reconstituted vial in the fridge
When in freeze dried form;

Room temp- 3 weeks

Refrigerated – 48 months+

Freezer – 48 months+


When reconstituted;

Refrigerated - 20-30 days

Freezer – 3 to 12 months
Epitalon should be injected twice a day, once in the morning and again at night. You should take 5 mg a day and should be cycled for 20 days every 3 months for best results
Do it once every 3 months and you should be good. If you don’t like the 20 day 5 mg cycle you could always switch to a 10 mg 10 day cycle but whatever works for you
No question everyone should be cycling Epitalon. If you consider yourself a looksmaxxer and don’t cycle Epitalon from now on you’re doing yourself a disservice.

@FlotPSL @Zagro @MaracasMogs
Bro is pumping out threads :feelswhat:

Mirin contributor maxxing :feelshmm:

I should post more :feelswhat:
 
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Reactions: Zagro and Aryan Incel
Bro is pumping out threads :feelswhat:

Mirin contributor maxxing :feelshmm:

I should post more :feelswhat:
nigga... Me, you and him all pretty much made the same thread about peptides, we need some new crazy shit in here
 
  • +1
Reactions: Zagro, Aryan Incel and Jattgymmaxx
nigga... Me, you and him all pretty much made the same thread about peptides, we need some new crazy shit in here
I’m gonna make a aqualayx guide but I’m too broke to buy

I’ll make a lgd cycle guide once I’m finished in like 10 weeks
 
  • +1
  • JFL
Reactions: Zagro, Aryan Incel and Linus1888
In the recent times peptides have gained a lot of popularity/ attention for their uses and how they could become a more natural alternative to things like roids and HGH. In this thread I will discuss the most popular and useful peptides and whether they should be used.


a peptide is a short chain of 2 to about 100 amino acids linked together by peptide bonds, acting as fundamental building blocks for proteins and carrying out various cellular functions, from signaling to providing structural support

It stimulates the pigment cells in your skin to produce more melanin, and this makes the skin look darker. This process also makes you more uv protective over time



View attachment 4135577
Facial Flushing


DermNethttps://dermnetnz.orgMelanotan II


Appetite Suppression

This is a rare side effect and shouldn't be relied upon for this effect and you should use proper appetite suppresses like glp-1 antagonists


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govActivation of the central melanocortin system chronically reduces body ...


Darkening Of Moles & Freckles

you should keep watch over any old or new moles to check if they change in shape or colour, if they do, get them checked by a healthcare professional. This is the most dangerously side effect


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govChanges of melanocytic lesions inducedby Melanotan injections ...


Lethargy, Nausea and Dizziness


Healthlinehttps://www.healthline.comTanning Nasal Spray: Should You Skip It?
For injection


For doses of less than 500mcg it would be best to use 2ml of water.

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 syringe

1 alcohol swab


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper. Wipe with the swab.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw your water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves, you can swirl or tilt the vial to help.


For Nasal

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 empty nasal spray bottle or 1 OTC nasal mist

1 syringe


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw 50 units of water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves,

6. Insert the syringe again and turn upside down.

7. Withdraw all of the liquid and remove the syringe.

8. Unscrew the cap of your nasal spray and slowly inject the liquid into the bottle.

9. If using an empty bottle you can now transfer the remainder of the water. Wait 2 hours before use.
When in freeze dried form they can be stored in many ways;

Room temperature – 12 months
Refrigerated – 48 months

Freezer – 48 months+


When reconstituted with sodium chloride it can be stored either;

Refrigerated – 1 month

Freezer – 48 months


When reconstituted with bacteriostatic water it should be stored;

Room temperature – 2 months

Refrigerated – 48 months
Melanotan 2 has a half life of ~33 hours, this allows you to be very flexible with dosing. However, it will always be better to inject in the morning or midday if getting natural UV exposure. If you are using sunbeds then inject about 20 minutes before exposure.


Recommended dosages start at 250mcg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 500mcg and stick at this point.


You can increase the dose as far as about 1mg but it is generally not advised - any higher and you'll be overdosing.
Once you have reached your desired level of tan then you can enter what is known as the 'maintenance phase'.


Although the level is different for most people it levels out at around 500mcg every 3 or 4 days and a sunbed session with every or every other dose.


This will allow you to maintain your tan through winter without much work.


If you notice at any point you're becoming darker, reduce the dose.


If you notice you are getting lighter, add in an extra dose or take up the second sunbed session if you didn't already.
MT2 is very useful for getting a tan and should be used as it has few drawbacks. However if you’re ethnic it should not be used under any circumstances as darker skin will failo

It works by binding with copper ions, acting as a naturally occurring human signaling peptide that promotes cell repair, regeneration, and tissue remodeling.

View attachment 4135623
Less bioavailable than the other two forms of GHK cu

https://pmc.ncbi.nlm.nih.gov/articles/PMC3359723/#:~:text=Therapeutic Administration of GHK-Cu&text=The peptide could be administered intravenously or orally when encapsulated into liposomes.


Less effective dues to the worse bioavailability


Anecdotally more some people have seen some like nausea, liver damage and fatigue
Directly targets the skin

https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/#:~:text=A number of clinical studies,aged skin, Krüger et al.


And proven to improve collagen

National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govRegenerative and Protective Actions of the GHK-Cu Peptide in the Light ...


However the amount absorbed by the skin is debatable and definitely not as effective as injectable GHK cu but could be used as well as injectable GHK cu
It has all the benefits I listed above in the benefit section


IMPORTANT
For best results inject it in your face. probably cheeks, jaw or scalp are best
Use around 3ml (300 units) of water per 50 mg of GHK cu


First, gather your supplies;

1 vial of GHK cu (50 mg)

1 vial/ampule of water (use bacteriostatic if you’re only concerned with collagen/ skin but use Phosphate Buffered Saline if you want all the benefits)

1 syringe

1 alcohol swab


1. Take your GHK cu vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.Draw 3.0 mL of bacteriostatic water/ Phosphate Buffered Saline into a sterile syringe.

3.Inject the water slowly along the vial wall to reduce foaming.

4.Gently swirl the vial—avoid vigorous shaking.

5.Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
When in freeze dried form it can be stored in many ways;

Refrigerated (has to be below 4 C) – 24 months

Freezer – 36 months


When reconstituted with Phosphate Buffered Saline it can be stored either;

Refrigerated - 1-8 weeks

Freezer – 3 to 12 months


When reconstituted with bacteriostatic water it should be stored;

Refrigerated – 6-8 weeks

Freezer- 6-12 months
GHK cu has a half life of ~2 hours, means you’re less flexible with dosing. It’s for this reason best to inject twice a day, once in the morning and again at night. For example 2.5 mg in the morning and 2.5 mg at night.


Recommended dosages start at 1-2.5 mg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 5 mg and stick at this point.

You can increase the dose as far as about 10 mg but it is generally not advised - any higher and you'll be get barely any extra benefits.
Once you have reached what you find to be a ideal dose for GHK cu you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
GHK cu is a very good peptide which everyone should be injecting.


Taking topical as well could improve collagen even more but it has been proven and is up for debate.


Oral shouldn’t be used under any circumstance.

These peptides increase certain hormones like igf1 and HGH. However the effects are less powerful/ significant than just using HGH.


This study shows HGH increases by 46% using CJC

https://pubmed.ncbi.nlm.nih.gov/16352683/#:~:text=Results: After a single injection of CJC-1295,,estimated half-life of CJC-1295 was 5.8-8.1 d.


This would be equivalent of going from 1 IU per day (this is what your body produces naturally) to 1.5 IU at the upper end


Compare this to how you could just inject HGH which will give much better results (4 IU +)


The reason that peptides will never be able to complete with something like HGH is because they it has a cap on how much you can improve which is because of your body.


In addition peptides are the same cost as roid/ gh something like HGH costs $2-$3 per day ($0.5 per 1 IU) compared to $1.75 per day ($80 per vial of 5 mg) with a CJC and ipamorelin blend


To conclude you should not use any peptides for muscle growth because they will give you worse results and just as expensive as something like HGH

It works by binding directly to the androgen receptors in the skin and hair and BLOCKS them so that no other androgen can bind. In this way, it can block both testosterone and DHT from damaging hair.

View attachment 4136325
Stops androgen binding to your hair follicles

Harley Street Hair Transplant Clinicshttps://www.harleystreethairtransplant.co.ukRU58841 For Hair Loss - A New Finasteride Alternative?


Could potentially stop synthetic androgen from binding to your hair like tren

https://pubmed.ncbi.nlm.nih.gov/9798729/#:~:text=Together our results suggest that,, androgenetic alopecia, and hirsutism.


99% gets broken down instantly into inert molecules with no effect on the body. Only 1% of the breakdown product acts as a systemic anti-androgen.
First, gather your supplies;

Dipropylene glycol

95% ethanol

Azelaic acid

A jewelery scale

RU58841 powder

Minoxodil powder

100 mL tinted glass bottles

1-2 mL eye dropper

Smidgen measuring spoon

Mini funnel

alcohol swab


1)The first step is to mix up some the solvent. You can do this approximately. It doesn't have to be perfect. Pour 20 mL of dipropylene glycol into the mini measure shot glass. Pour this into your 100 mL tinted glass bottle (using the funnel). Then measure 30 mL of ethanol in the shot glass, and also pour this into your 100 mL tinted bottle. You now have 50 mL of 60/40 ethanol/dipropylene-glycol solution. If you want more, repeat this process once more into the same bottle and you have 100 mL which will last almost 2 months.

2)Use your pipette and draw up ~2 mL of the 60/40 solvent. Put it in the shot glass. You will be mixing your day’s application in this shot glass in this way each day.

3)A dose of 100 mg RU58841 daily works best. You can go as low as 50 mg if you're lucky. Or as high as 150 mg whatever works best. Use 2 flat smidgens of RU58841 which works out to almost exactly 100 mg.

4)do the same with the minox

5)and azelaic acid

6)Dump all those flat smidgen scoops of your powders into the shot glass containing 2 mL solvent.

7)Swirl it to mix. Letting it sit 5-10 minutes often helps.

8)Next once it is fully mixed, use the dropper to draw up ~0.25 mL of solution at a time and apply to scalp, one area at a time. Rub it in each time to spread it around. You’ll want to make sure you especially get the frontal hairline, temples, corners, and crown. 2 mL is just enough to get a good coverage. If you want to be sure you are covering well enough, 2.5 mL is good too.
When in powder form it can be stored in many ways;

Room temp -2 years

Refrigerated – almost indefinitely

Freezer – almost indefinitely
RU 58841 has a half life of ~1 hours, when used orally in mice, however no data has been done for topical use but we could estimate it would last around 12-24 hours means you’re flexible with dosing. It’s for this reason best to use once a day.

Recommended dosages start at use between 50-150 mg daily
Once you have reached what you find to be a ideal dose for RU you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
RU 58841 should be used by everyone especially if you are dealing with hair loss.


With isnt only negative being how tedious it is to make.


However the benefits and potential shows it could potentially mog something like Dutasteride

Most of the information came from @Sadist and @Copercel threads so credit to them for this section


Epitalon enhances telomerase activity, which protects telomeres from shortening during cell division.

View attachment 4136336
Use around 1 ml of BAC to a 10 mg vial


First, gather your supplies;

1 vial of epitalon (10mg)

1 vial/ampule of water

1 syringe

1 alcohol swab


1)Clean everything with alcohol pads: vial tops, your hands, etc.

2)Draw up 1-2 mL of bacteriostatic waterusing a sterile syringe.

3)Slowly inject the water into the Epitalonvial (aim against the glass wall to avoid foaming).

4)Let the powder dissolve gently, do not shake. Swirl lightly if needed.

5)Store the reconstituted vial in the fridge
When in freeze dried form;

Room temp- 3 weeks

Refrigerated – 48 months+

Freezer – 48 months+


When reconstituted;

Refrigerated - 20-30 days

Freezer – 3 to 12 months
Epitalon should be injected twice a day, once in the morning and again at night. You should take 5 mg a day and should be cycled for 20 days every 3 months for best results
Do it once every 3 months and you should be good. If you don’t like the 20 day 5 mg cycle you could always switch to a 10 mg 10 day cycle but whatever works for you
No question everyone should be cycling Epitalon. If you consider yourself a looksmaxxer and don’t cycle Epitalon from now on you’re doing yourself a disservice.

@FlotPSL @Zagro @MaracasMogs
Peptides are cope and are the equivalent of getting 1 more hour of sleep a night JFL this shit ain't helping anyone other then 14 year olds
 
  • Hmm...
  • +1
Reactions: Zagro and Linus1888
I’m gonna make a aqualayx guide but I’m too broke to buy

I’ll make a lgd cycle guide once I’m finished in like 10 weeks
guide, guide, guide. Nigga put the blue checkmark in the bag
Fw carti but that fanbase been so annoying ever since wlr v0 qahycxw0nh8a1
 
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  • JFL
Reactions: Zagro and Jattgymmaxx
Peptides are cope and are the equivalent of getting 1 more hour of sleep a night JFL this shit ain't helping anyone other then 14 year olds
yeah nigga 1 hour of sleep gets me the same tan as melanotan 2. 1 hour of sleep gives me clearer skin than ghk-cu.

wtf you smokin lil ass nigga?
 
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Reactions: Zagro and Tigermoggerlol
yeah nigga 1 hour of sleep gets me the same tan as melanotan 2. 1 hour of sleep gives me clearer skin than ghk-cu.

wtf you smokin lil ass nigga?
I was talking Abt the ipam and cjc and all the GS. But yeah mela is good if u wanna look like a shitskin and ghk-cu is good yeah
 
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Reactions: Zagro
In the recent times peptides have gained a lot of popularity/ attention for their uses and how they could become a more natural alternative to things like roids and HGH. In this thread I will discuss the most popular and useful peptides and whether they should be used.


a peptide is a short chain of 2 to about 100 amino acids linked together by peptide bonds, acting as fundamental building blocks for proteins and carrying out various cellular functions, from signaling to providing structural support

It stimulates the pigment cells in your skin to produce more melanin, and this makes the skin look darker. This process also makes you more uv protective over time



View attachment 4135577
Facial Flushing


DermNethttps://dermnetnz.orgMelanotan II


Appetite Suppression

This is a rare side effect and shouldn't be relied upon for this effect and you should use proper appetite suppresses like glp-1 antagonists


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govActivation of the central melanocortin system chronically reduces body ...


Darkening Of Moles & Freckles

you should keep watch over any old or new moles to check if they change in shape or colour, if they do, get them checked by a healthcare professional. This is the most dangerously side effect


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govChanges of melanocytic lesions inducedby Melanotan injections ...


Lethargy, Nausea and Dizziness


Healthlinehttps://www.healthline.comTanning Nasal Spray: Should You Skip It?
For injection


For doses of less than 500mcg it would be best to use 2ml of water.

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 syringe

1 alcohol swab


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper. Wipe with the swab.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw your water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves, you can swirl or tilt the vial to help.


For Nasal

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 empty nasal spray bottle or 1 OTC nasal mist

1 syringe


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw 50 units of water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves,

6. Insert the syringe again and turn upside down.

7. Withdraw all of the liquid and remove the syringe.

8. Unscrew the cap of your nasal spray and slowly inject the liquid into the bottle.

9. If using an empty bottle you can now transfer the remainder of the water. Wait 2 hours before use.
When in freeze dried form they can be stored in many ways;

Room temperature – 12 months
Refrigerated – 48 months

Freezer – 48 months+


When reconstituted with sodium chloride it can be stored either;

Refrigerated – 1 month

Freezer – 48 months


When reconstituted with bacteriostatic water it should be stored;

Room temperature – 2 months

Refrigerated – 48 months
Melanotan 2 has a half life of ~33 hours, this allows you to be very flexible with dosing. However, it will always be better to inject in the morning or midday if getting natural UV exposure. If you are using sunbeds then inject about 20 minutes before exposure.


Recommended dosages start at 250mcg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 500mcg and stick at this point.


You can increase the dose as far as about 1mg but it is generally not advised - any higher and you'll be overdosing.
Once you have reached your desired level of tan then you can enter what is known as the 'maintenance phase'.


Although the level is different for most people it levels out at around 500mcg every 3 or 4 days and a sunbed session with every or every other dose.


This will allow you to maintain your tan through winter without much work.


If you notice at any point you're becoming darker, reduce the dose.


If you notice you are getting lighter, add in an extra dose or take up the second sunbed session if you didn't already.
MT2 is very useful for getting a tan and should be used as it has few drawbacks. However if you’re ethnic it should not be used under any circumstances as darker skin will failo

It works by binding with copper ions, acting as a naturally occurring human signaling peptide that promotes cell repair, regeneration, and tissue remodeling.

View attachment 4135623
Less bioavailable than the other two forms of GHK cu

https://pmc.ncbi.nlm.nih.gov/articles/PMC3359723/#:~:text=Therapeutic Administration of GHK-Cu&text=The peptide could be administered intravenously or orally when encapsulated into liposomes.


Less effective dues to the worse bioavailability


Anecdotally more some people have seen some like nausea, liver damage and fatigue
Directly targets the skin

https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/#:~:text=A number of clinical studies,aged skin, Krüger et al.


And proven to improve collagen

National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govRegenerative and Protective Actions of the GHK-Cu Peptide in the Light ...


However the amount absorbed by the skin is debatable and definitely not as effective as injectable GHK cu but could be used as well as injectable GHK cu
It has all the benefits I listed above in the benefit section


IMPORTANT
For best results inject it in your face. probably cheeks, jaw or scalp are best
Use around 3ml (300 units) of water per 50 mg of GHK cu


First, gather your supplies;

1 vial of GHK cu (50 mg)

1 vial/ampule of water (use bacteriostatic if you’re only concerned with collagen/ skin but use Phosphate Buffered Saline if you want all the benefits)

1 syringe

1 alcohol swab


1. Take your GHK cu vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.Draw 3.0 mL of bacteriostatic water/ Phosphate Buffered Saline into a sterile syringe.

3.Inject the water slowly along the vial wall to reduce foaming.

4.Gently swirl the vial—avoid vigorous shaking.

5.Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
When in freeze dried form it can be stored in many ways;

Refrigerated (has to be below 4 C) – 24 months

Freezer – 36 months


When reconstituted with Phosphate Buffered Saline it can be stored either;

Refrigerated - 1-8 weeks

Freezer – 3 to 12 months


When reconstituted with bacteriostatic water it should be stored;

Refrigerated – 6-8 weeks

Freezer- 6-12 months
GHK cu has a half life of ~2 hours, means you’re less flexible with dosing. It’s for this reason best to inject twice a day, once in the morning and again at night. For example 2.5 mg in the morning and 2.5 mg at night.


Recommended dosages start at 1-2.5 mg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 5 mg and stick at this point.

You can increase the dose as far as about 10 mg but it is generally not advised - any higher and you'll be get barely any extra benefits.
Once you have reached what you find to be a ideal dose for GHK cu you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
GHK cu is a very good peptide which everyone should be injecting.


Taking topical as well could improve collagen even more but it has been proven and is up for debate.


Oral shouldn’t be used under any circumstance.

These peptides increase certain hormones like igf1 and HGH. However the effects are less powerful/ significant than just using HGH.


This study shows HGH increases by 46% using CJC

https://pubmed.ncbi.nlm.nih.gov/16352683/#:~:text=Results: After a single injection of CJC-1295,,estimated half-life of CJC-1295 was 5.8-8.1 d.


This would be equivalent of going from 1 IU per day (this is what your body produces naturally) to 1.5 IU at the upper end


Compare this to how you could just inject HGH which will give much better results (4 IU +)


The reason that peptides will never be able to complete with something like HGH is because they it has a cap on how much you can improve which is because of your body.


In addition peptides are the same cost as roid/ gh something like HGH costs $2-$3 per day ($0.5 per 1 IU) compared to $1.75 per day ($80 per vial of 5 mg) with a CJC and ipamorelin blend


To conclude you should not use any peptides for muscle growth because they will give you worse results and just as expensive as something like HGH

It works by binding directly to the androgen receptors in the skin and hair and BLOCKS them so that no other androgen can bind. In this way, it can block both testosterone and DHT from damaging hair.

View attachment 4136325
Stops androgen binding to your hair follicles

Harley Street Hair Transplant Clinicshttps://www.harleystreethairtransplant.co.ukRU58841 For Hair Loss - A New Finasteride Alternative?


Could potentially stop synthetic androgen from binding to your hair like tren

https://pubmed.ncbi.nlm.nih.gov/9798729/#:~:text=Together our results suggest that,, androgenetic alopecia, and hirsutism.


99% gets broken down instantly into inert molecules with no effect on the body. Only 1% of the breakdown product acts as a systemic anti-androgen.
First, gather your supplies;

Dipropylene glycol

95% ethanol

Azelaic acid

A jewelery scale

RU58841 powder

Minoxodil powder

100 mL tinted glass bottles

1-2 mL eye dropper

Smidgen measuring spoon

Mini funnel

alcohol swab


1)The first step is to mix up some the solvent. You can do this approximately. It doesn't have to be perfect. Pour 20 mL of dipropylene glycol into the mini measure shot glass. Pour this into your 100 mL tinted glass bottle (using the funnel). Then measure 30 mL of ethanol in the shot glass, and also pour this into your 100 mL tinted bottle. You now have 50 mL of 60/40 ethanol/dipropylene-glycol solution. If you want more, repeat this process once more into the same bottle and you have 100 mL which will last almost 2 months.

2)Use your pipette and draw up ~2 mL of the 60/40 solvent. Put it in the shot glass. You will be mixing your day’s application in this shot glass in this way each day.

3)A dose of 100 mg RU58841 daily works best. You can go as low as 50 mg if you're lucky. Or as high as 150 mg whatever works best. Use 2 flat smidgens of RU58841 which works out to almost exactly 100 mg.

4)do the same with the minox

5)and azelaic acid

6)Dump all those flat smidgen scoops of your powders into the shot glass containing 2 mL solvent.

7)Swirl it to mix. Letting it sit 5-10 minutes often helps.

8)Next once it is fully mixed, use the dropper to draw up ~0.25 mL of solution at a time and apply to scalp, one area at a time. Rub it in each time to spread it around. You’ll want to make sure you especially get the frontal hairline, temples, corners, and crown. 2 mL is just enough to get a good coverage. If you want to be sure you are covering well enough, 2.5 mL is good too.
When in powder form it can be stored in many ways;

Room temp -2 years

Refrigerated – almost indefinitely

Freezer – almost indefinitely
RU 58841 has a half life of ~1 hours, when used orally in mice, however no data has been done for topical use but we could estimate it would last around 12-24 hours means you’re flexible with dosing. It’s for this reason best to use once a day.

Recommended dosages start at use between 50-150 mg daily
Once you have reached what you find to be a ideal dose for RU you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
RU 58841 should be used by everyone especially if you are dealing with hair loss.


With isnt only negative being how tedious it is to make.


However the benefits and potential shows it could potentially mog something like Dutasteride

Most of the information came from @Sadist and @Copercel threads so credit to them for this section


Epitalon enhances telomerase activity, which protects telomeres from shortening during cell division.

View attachment 4136336
Use around 1 ml of BAC to a 10 mg vial


First, gather your supplies;

1 vial of epitalon (10mg)

1 vial/ampule of water

1 syringe

1 alcohol swab


1)Clean everything with alcohol pads: vial tops, your hands, etc.

2)Draw up 1-2 mL of bacteriostatic waterusing a sterile syringe.

3)Slowly inject the water into the Epitalonvial (aim against the glass wall to avoid foaming).

4)Let the powder dissolve gently, do not shake. Swirl lightly if needed.

5)Store the reconstituted vial in the fridge
When in freeze dried form;

Room temp- 3 weeks

Refrigerated – 48 months+

Freezer – 48 months+


When reconstituted;

Refrigerated - 20-30 days

Freezer – 3 to 12 months
Epitalon should be injected twice a day, once in the morning and again at night. You should take 5 mg a day and should be cycled for 20 days every 3 months for best results
Do it once every 3 months and you should be good. If you don’t like the 20 day 5 mg cycle you could always switch to a 10 mg 10 day cycle but whatever works for you
No question everyone should be cycling Epitalon. If you consider yourself a looksmaxxer and don’t cycle Epitalon from now on you’re doing yourself a disservice.

@FlotPSL @Zagro @MaracasMogs
Bro how tf do you do this so fast
 
  • JFL
  • +1
Reactions: Zagro and Aryan Incel
Mirin but were not jonas
 
  • +1
Reactions: Zagro and Aryan Incel
mirin the effort
 
  • +1
Reactions: Zagro, MaracasMogs and Aryan Incel
Bump
 
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Reactions: MaracasMogs, unon and Zagro
Bump :Comfy:
 
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Reactions: Aryan Incel, MaracasMogs and unon
In the recent times peptides have gained a lot of popularity/ attention for their uses and how they could become a more natural alternative to things like roids and HGH. In this thread I will discuss the most popular and useful peptides and whether they should be used.


a peptide is a short chain of 2 to about 100 amino acids linked together by peptide bonds, acting as fundamental building blocks for proteins and carrying out various cellular functions, from signaling to providing structural support

It stimulates the pigment cells in your skin to produce more melanin, and this makes the skin look darker. This process also makes you more uv protective over time



View attachment 4135577
Facial Flushing


DermNethttps://dermnetnz.orgMelanotan II


Appetite Suppression

This is a rare side effect and shouldn't be relied upon for this effect and you should use proper appetite suppresses like glp-1 antagonists


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govActivation of the central melanocortin system chronically reduces body ...


Darkening Of Moles & Freckles

you should keep watch over any old or new moles to check if they change in shape or colour, if they do, get them checked by a healthcare professional. This is the most dangerously side effect


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govChanges of melanocytic lesions inducedby Melanotan injections ...


Lethargy, Nausea and Dizziness


Healthlinehttps://www.healthline.comTanning Nasal Spray: Should You Skip It?
For injection


For doses of less than 500mcg it would be best to use 2ml of water.

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 syringe

1 alcohol swab


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper. Wipe with the swab.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw your water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves, you can swirl or tilt the vial to help.


For Nasal

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 empty nasal spray bottle or 1 OTC nasal mist

1 syringe


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw 50 units of water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves,

6. Insert the syringe again and turn upside down.

7. Withdraw all of the liquid and remove the syringe.

8. Unscrew the cap of your nasal spray and slowly inject the liquid into the bottle.

9. If using an empty bottle you can now transfer the remainder of the water. Wait 2 hours before use.
When in freeze dried form they can be stored in many ways;

Room temperature – 12 months
Refrigerated – 48 months

Freezer – 48 months+


When reconstituted with sodium chloride it can be stored either;

Refrigerated – 1 month

Freezer – 48 months


When reconstituted with bacteriostatic water it should be stored;

Room temperature – 2 months

Refrigerated – 48 months
Melanotan 2 has a half life of ~33 hours, this allows you to be very flexible with dosing. However, it will always be better to inject in the morning or midday if getting natural UV exposure. If you are using sunbeds then inject about 20 minutes before exposure.


Recommended dosages start at 250mcg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 500mcg and stick at this point.


You can increase the dose as far as about 1mg but it is generally not advised - any higher and you'll be overdosing.
Once you have reached your desired level of tan then you can enter what is known as the 'maintenance phase'.


Although the level is different for most people it levels out at around 500mcg every 3 or 4 days and a sunbed session with every or every other dose.


This will allow you to maintain your tan through winter without much work.


If you notice at any point you're becoming darker, reduce the dose.


If you notice you are getting lighter, add in an extra dose or take up the second sunbed session if you didn't already.
MT2 is very useful for getting a tan and should be used as it has few drawbacks. However if you’re ethnic it should not be used under any circumstances as darker skin will failo

It works by binding with copper ions, acting as a naturally occurring human signaling peptide that promotes cell repair, regeneration, and tissue remodeling.

View attachment 4135623
Less bioavailable than the other two forms of GHK cu

https://pmc.ncbi.nlm.nih.gov/articles/PMC3359723/#:~:text=Therapeutic Administration of GHK-Cu&text=The peptide could be administered intravenously or orally when encapsulated into liposomes.


Less effective dues to the worse bioavailability


Anecdotally more some people have seen some like nausea, liver damage and fatigue
Directly targets the skin

https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/#:~:text=A number of clinical studies,aged skin, Krüger et al.


And proven to improve collagen

National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govRegenerative and Protective Actions of the GHK-Cu Peptide in the Light ...


However the amount absorbed by the skin is debatable and definitely not as effective as injectable GHK cu but could be used as well as injectable GHK cu
It has all the benefits I listed above in the benefit section


IMPORTANT
For best results inject it in your face. probably cheeks, jaw or scalp are best
Use around 3ml (300 units) of water per 50 mg of GHK cu


First, gather your supplies;

1 vial of GHK cu (50 mg)

1 vial/ampule of water (use bacteriostatic if you’re only concerned with collagen/ skin but use Phosphate Buffered Saline if you want all the benefits)

1 syringe

1 alcohol swab


1. Take your GHK cu vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.Draw 3.0 mL of bacteriostatic water/ Phosphate Buffered Saline into a sterile syringe.

3.Inject the water slowly along the vial wall to reduce foaming.

4.Gently swirl the vial—avoid vigorous shaking.

5.Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
When in freeze dried form it can be stored in many ways;

Refrigerated (has to be below 4 C) – 24 months

Freezer – 36 months


When reconstituted with Phosphate Buffered Saline it can be stored either;

Refrigerated - 1-8 weeks

Freezer – 3 to 12 months


When reconstituted with bacteriostatic water it should be stored;

Refrigerated – 6-8 weeks

Freezer- 6-12 months
GHK cu has a half life of ~2 hours, means you’re less flexible with dosing. It’s for this reason best to inject twice a day, once in the morning and again at night. For example 2.5 mg in the morning and 2.5 mg at night.


Recommended dosages start at 1-2.5 mg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 5 mg and stick at this point.

You can increase the dose as far as about 10 mg but it is generally not advised - any higher and you'll be get barely any extra benefits.
Once you have reached what you find to be a ideal dose for GHK cu you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
GHK cu is a very good peptide which everyone should be injecting.


Taking topical as well could improve collagen even more but it has been proven and is up for debate.


Oral shouldn’t be used under any circumstance.

These peptides increase certain hormones like igf1 and HGH. However the effects are less powerful/ significant than just using HGH.


This study shows HGH increases by 46% using CJC

https://pubmed.ncbi.nlm.nih.gov/16352683/#:~:text=Results: After a single injection of CJC-1295,,estimated half-life of CJC-1295 was 5.8-8.1 d.


This would be equivalent of going from 1 IU per day (this is what your body produces naturally) to 1.5 IU at the upper end


Compare this to how you could just inject HGH which will give much better results (4 IU +)


The reason that peptides will never be able to complete with something like HGH is because they it has a cap on how much you can improve which is because of your body.


In addition peptides are the same cost as roid/ gh something like HGH costs $2-$3 per day ($0.5 per 1 IU) compared to $1.75 per day ($80 per vial of 5 mg) with a CJC and ipamorelin blend


To conclude you should not use any peptides for muscle growth because they will give you worse results and just as expensive as something like HGH

It works by binding directly to the androgen receptors in the skin and hair and BLOCKS them so that no other androgen can bind. In this way, it can block both testosterone and DHT from damaging hair.

View attachment 4136325
Stops androgen binding to your hair follicles

Harley Street Hair Transplant Clinicshttps://www.harleystreethairtransplant.co.ukRU58841 For Hair Loss - A New Finasteride Alternative?


Could potentially stop synthetic androgen from binding to your hair like tren

https://pubmed.ncbi.nlm.nih.gov/9798729/#:~:text=Together our results suggest that,, androgenetic alopecia, and hirsutism.


99% gets broken down instantly into inert molecules with no effect on the body. Only 1% of the breakdown product acts as a systemic anti-androgen.
First, gather your supplies;

Dipropylene glycol

95% ethanol

Azelaic acid

A jewelery scale

RU58841 powder

Minoxodil powder

100 mL tinted glass bottles

1-2 mL eye dropper

Smidgen measuring spoon

Mini funnel

alcohol swab


1)The first step is to mix up some the solvent. You can do this approximately. It doesn't have to be perfect. Pour 20 mL of dipropylene glycol into the mini measure shot glass. Pour this into your 100 mL tinted glass bottle (using the funnel). Then measure 30 mL of ethanol in the shot glass, and also pour this into your 100 mL tinted bottle. You now have 50 mL of 60/40 ethanol/dipropylene-glycol solution. If you want more, repeat this process once more into the same bottle and you have 100 mL which will last almost 2 months.

2)Use your pipette and draw up ~2 mL of the 60/40 solvent. Put it in the shot glass. You will be mixing your day’s application in this shot glass in this way each day.

3)A dose of 100 mg RU58841 daily works best. You can go as low as 50 mg if you're lucky. Or as high as 150 mg whatever works best. Use 2 flat smidgens of RU58841 which works out to almost exactly 100 mg.

4)do the same with the minox

5)and azelaic acid

6)Dump all those flat smidgen scoops of your powders into the shot glass containing 2 mL solvent.

7)Swirl it to mix. Letting it sit 5-10 minutes often helps.

8)Next once it is fully mixed, use the dropper to draw up ~0.25 mL of solution at a time and apply to scalp, one area at a time. Rub it in each time to spread it around. You’ll want to make sure you especially get the frontal hairline, temples, corners, and crown. 2 mL is just enough to get a good coverage. If you want to be sure you are covering well enough, 2.5 mL is good too.
When in powder form it can be stored in many ways;

Room temp -2 years

Refrigerated – almost indefinitely

Freezer – almost indefinitely
RU 58841 has a half life of ~1 hours, when used orally in mice, however no data has been done for topical use but we could estimate it would last around 12-24 hours means you’re flexible with dosing. It’s for this reason best to use once a day.

Recommended dosages start at use between 50-150 mg daily
Once you have reached what you find to be a ideal dose for RU you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
RU 58841 should be used by everyone especially if you are dealing with hair loss.


With isnt only negative being how tedious it is to make.


However the benefits and potential shows it could potentially mog something like Dutasteride

Most of the information came from @Sadist and @Copercel threads so credit to them for this section


Epitalon enhances telomerase activity, which protects telomeres from shortening during cell division.

View attachment 4136336
Use around 1 ml of BAC to a 10 mg vial


First, gather your supplies;

1 vial of epitalon (10mg)

1 vial/ampule of water

1 syringe

1 alcohol swab


1)Clean everything with alcohol pads: vial tops, your hands, etc.

2)Draw up 1-2 mL of bacteriostatic waterusing a sterile syringe.

3)Slowly inject the water into the Epitalonvial (aim against the glass wall to avoid foaming).

4)Let the powder dissolve gently, do not shake. Swirl lightly if needed.

5)Store the reconstituted vial in the fridge
When in freeze dried form;

Room temp- 3 weeks

Refrigerated – 48 months+

Freezer – 48 months+


When reconstituted;

Refrigerated - 20-30 days

Freezer – 3 to 12 months
Epitalon should be injected twice a day, once in the morning and again at night. You should take 5 mg a day and should be cycled for 20 days every 3 months for best results
Do it once every 3 months and you should be good. If you don’t like the 20 day 5 mg cycle you could always switch to a 10 mg 10 day cycle but whatever works for you
No question everyone should be cycling Epitalon. If you consider yourself a looksmaxxer and don’t cycle Epitalon from now on you’re doing yourself a disservice.

@FlotPSL @Zagro @MaracasMogs
Wouldn't touch any of these besides ghk possibly melanotan. Just roid bru
 
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  • +1
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In the recent times peptides have gained a lot of popularity/ attention for their uses and how they could become a more natural alternative to things like roids and HGH. In this thread I will discuss the most popular and useful peptides and whether they should be used.


a peptide is a short chain of 2 to about 100 amino acids linked together by peptide bonds, acting as fundamental building blocks for proteins and carrying out various cellular functions, from signaling to providing structural support

It stimulates the pigment cells in your skin to produce more melanin, and this makes the skin look darker. This process also makes you more uv protective over time



View attachment 4135577
Facial Flushing


DermNethttps://dermnetnz.orgMelanotan II


Appetite Suppression

This is a rare side effect and shouldn't be relied upon for this effect and you should use proper appetite suppresses like glp-1 antagonists


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govActivation of the central melanocortin system chronically reduces body ...


Darkening Of Moles & Freckles

you should keep watch over any old or new moles to check if they change in shape or colour, if they do, get them checked by a healthcare professional. This is the most dangerously side effect


National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govChanges of melanocytic lesions inducedby Melanotan injections ...


Lethargy, Nausea and Dizziness


Healthlinehttps://www.healthline.comTanning Nasal Spray: Should You Skip It?
For injection


For doses of less than 500mcg it would be best to use 2ml of water.

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 syringe

1 alcohol swab


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper. Wipe with the swab.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw your water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves, you can swirl or tilt the vial to help.


For Nasal

First, gather your supplies;

1 vial of Melanotan

1 vial/ampule of water

1 empty nasal spray bottle or 1 OTC nasal mist

1 syringe


1. Take your Melanotan vial and take off the top of the vial to reveal the rubber stopper.

2.a. If using bacteriostatic water, pop off the top of the vial to reveal the rubber stopper.

b. If using sodium chloride, twist off the top of the ampule

3. Next insert a syringe into the vial/ampule and hold it upside down.

4. Withdraw 50 units of water and inject it slowly into the Melanotan vial aiming at the side, not the powder.

5. Place in the fridge for a few hours or overnight while the powder dissolves,

6. Insert the syringe again and turn upside down.

7. Withdraw all of the liquid and remove the syringe.

8. Unscrew the cap of your nasal spray and slowly inject the liquid into the bottle.

9. If using an empty bottle you can now transfer the remainder of the water. Wait 2 hours before use.
When in freeze dried form they can be stored in many ways;

Room temperature – 12 months
Refrigerated – 48 months

Freezer – 48 months+


When reconstituted with sodium chloride it can be stored either;

Refrigerated – 1 month

Freezer – 48 months


When reconstituted with bacteriostatic water it should be stored;

Room temperature – 2 months

Refrigerated – 48 months
Melanotan 2 has a half life of ~33 hours, this allows you to be very flexible with dosing. However, it will always be better to inject in the morning or midday if getting natural UV exposure. If you are using sunbeds then inject about 20 minutes before exposure.


Recommended dosages start at 250mcg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 500mcg and stick at this point.


You can increase the dose as far as about 1mg but it is generally not advised - any higher and you'll be overdosing.
Once you have reached your desired level of tan then you can enter what is known as the 'maintenance phase'.


Although the level is different for most people it levels out at around 500mcg every 3 or 4 days and a sunbed session with every or every other dose.


This will allow you to maintain your tan through winter without much work.


If you notice at any point you're becoming darker, reduce the dose.


If you notice you are getting lighter, add in an extra dose or take up the second sunbed session if you didn't already.
MT2 is very useful for getting a tan and should be used as it has few drawbacks. However if you’re ethnic it should not be used under any circumstances as darker skin will failo

It works by binding with copper ions, acting as a naturally occurring human signaling peptide that promotes cell repair, regeneration, and tissue remodeling.

View attachment 4135623
Less bioavailable than the other two forms of GHK cu

https://pmc.ncbi.nlm.nih.gov/articles/PMC3359723/#:~:text=Therapeutic Administration of GHK-Cu&text=The peptide could be administered intravenously or orally when encapsulated into liposomes.


Less effective dues to the worse bioavailability


Anecdotally more some people have seen some like nausea, liver damage and fatigue
Directly targets the skin

https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/#:~:text=A number of clinical studies,aged skin, Krüger et al.


And proven to improve collagen

National Institutes of Health (NIH) | (.gov)https://pmc.ncbi.nlm.nih.govRegenerative and Protective Actions of the GHK-Cu Peptide in the Light ...


However the amount absorbed by the skin is debatable and definitely not as effective as injectable GHK cu but could be used as well as injectable GHK cu
It has all the benefits I listed above in the benefit section


IMPORTANT
For best results inject it in your face. probably cheeks, jaw or scalp are best
Use around 3ml (300 units) of water per 50 mg of GHK cu


First, gather your supplies;

1 vial of GHK cu (50 mg)

1 vial/ampule of water (use bacteriostatic if you’re only concerned with collagen/ skin but use Phosphate Buffered Saline if you want all the benefits)

1 syringe

1 alcohol swab


1. Take your GHK cu vial and take off the top of the vial to reveal the rubber stopper. Wipe with the antibacterial swab.

2.Draw 3.0 mL of bacteriostatic water/ Phosphate Buffered Saline into a sterile syringe.

3.Inject the water slowly along the vial wall to reduce foaming.

4.Gently swirl the vial—avoid vigorous shaking.

5.Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
When in freeze dried form it can be stored in many ways;

Refrigerated (has to be below 4 C) – 24 months

Freezer – 36 months


When reconstituted with Phosphate Buffered Saline it can be stored either;

Refrigerated - 1-8 weeks

Freezer – 3 to 12 months


When reconstituted with bacteriostatic water it should be stored;

Refrigerated – 6-8 weeks

Freezer- 6-12 months
GHK cu has a half life of ~2 hours, means you’re less flexible with dosing. It’s for this reason best to inject twice a day, once in the morning and again at night. For example 2.5 mg in the morning and 2.5 mg at night.


Recommended dosages start at 1-2.5 mg every day to help your body acclimatize to the peptide and minimize the side effects. You can continue with this dose indefinitely if you are intending to do a low dosage regimen.


If you want to dose higher, after 2-4 days, whenever you feel comfortable, up the dose to 5 mg and stick at this point.

You can increase the dose as far as about 10 mg but it is generally not advised - any higher and you'll be get barely any extra benefits.
Once you have reached what you find to be a ideal dose for GHK cu you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
GHK cu is a very good peptide which everyone should be injecting.


Taking topical as well could improve collagen even more but it has been proven and is up for debate.


Oral shouldn’t be used under any circumstance.

These peptides increase certain hormones like igf1 and HGH. However the effects are less powerful/ significant than just using HGH.


This study shows HGH increases by 46% using CJC

https://pubmed.ncbi.nlm.nih.gov/16352683/#:~:text=Results: After a single injection of CJC-1295,,estimated half-life of CJC-1295 was 5.8-8.1 d.


This would be equivalent of going from 1 IU per day (this is what your body produces naturally) to 1.5 IU at the upper end


Compare this to how you could just inject HGH which will give much better results (4 IU +)


The reason that peptides will never be able to complete with something like HGH is because they it has a cap on how much you can improve which is because of your body.


In addition peptides are the same cost as roid/ gh something like HGH costs $2-$3 per day ($0.5 per 1 IU) compared to $1.75 per day ($80 per vial of 5 mg) with a CJC and ipamorelin blend


To conclude you should not use any peptides for muscle growth because they will give you worse results and just as expensive as something like HGH

It works by binding directly to the androgen receptors in the skin and hair and BLOCKS them so that no other androgen can bind. In this way, it can block both testosterone and DHT from damaging hair.

View attachment 4136325
Stops androgen binding to your hair follicles

Harley Street Hair Transplant Clinicshttps://www.harleystreethairtransplant.co.ukRU58841 For Hair Loss - A New Finasteride Alternative?


Could potentially stop synthetic androgen from binding to your hair like tren

https://pubmed.ncbi.nlm.nih.gov/9798729/#:~:text=Together our results suggest that,, androgenetic alopecia, and hirsutism.


99% gets broken down instantly into inert molecules with no effect on the body. Only 1% of the breakdown product acts as a systemic anti-androgen.
First, gather your supplies;

Dipropylene glycol

95% ethanol

Azelaic acid

A jewelery scale

RU58841 powder

Minoxodil powder

100 mL tinted glass bottles

1-2 mL eye dropper

Smidgen measuring spoon

Mini funnel

alcohol swab


1)The first step is to mix up some the solvent. You can do this approximately. It doesn't have to be perfect. Pour 20 mL of dipropylene glycol into the mini measure shot glass. Pour this into your 100 mL tinted glass bottle (using the funnel). Then measure 30 mL of ethanol in the shot glass, and also pour this into your 100 mL tinted bottle. You now have 50 mL of 60/40 ethanol/dipropylene-glycol solution. If you want more, repeat this process once more into the same bottle and you have 100 mL which will last almost 2 months.

2)Use your pipette and draw up ~2 mL of the 60/40 solvent. Put it in the shot glass. You will be mixing your day’s application in this shot glass in this way each day.

3)A dose of 100 mg RU58841 daily works best. You can go as low as 50 mg if you're lucky. Or as high as 150 mg whatever works best. Use 2 flat smidgens of RU58841 which works out to almost exactly 100 mg.

4)do the same with the minox

5)and azelaic acid

6)Dump all those flat smidgen scoops of your powders into the shot glass containing 2 mL solvent.

7)Swirl it to mix. Letting it sit 5-10 minutes often helps.

8)Next once it is fully mixed, use the dropper to draw up ~0.25 mL of solution at a time and apply to scalp, one area at a time. Rub it in each time to spread it around. You’ll want to make sure you especially get the frontal hairline, temples, corners, and crown. 2 mL is just enough to get a good coverage. If you want to be sure you are covering well enough, 2.5 mL is good too.
When in powder form it can be stored in many ways;

Room temp -2 years

Refrigerated – almost indefinitely

Freezer – almost indefinitely
RU 58841 has a half life of ~1 hours, when used orally in mice, however no data has been done for topical use but we could estimate it would last around 12-24 hours means you’re flexible with dosing. It’s for this reason best to use once a day.

Recommended dosages start at use between 50-150 mg daily
Once you have reached what you find to be a ideal dose for RU you should continue with it indefinitely, the ideal dose will vary person to person so I can’t say exactly what it will be but you can find it through trial and error.


If you experience any adverse side effects lowering the dosage seems to fix most of these in a couple of days/ weeks.
RU 58841 should be used by everyone especially if you are dealing with hair loss.


With isnt only negative being how tedious it is to make.


However the benefits and potential shows it could potentially mog something like Dutasteride

Most of the information came from @Sadist and @Copercel threads so credit to them for this section


Epitalon enhances telomerase activity, which protects telomeres from shortening during cell division.

View attachment 4136336
Use around 1 ml of BAC to a 10 mg vial


First, gather your supplies;

1 vial of epitalon (10mg)

1 vial/ampule of water

1 syringe

1 alcohol swab


1)Clean everything with alcohol pads: vial tops, your hands, etc.

2)Draw up 1-2 mL of bacteriostatic waterusing a sterile syringe.

3)Slowly inject the water into the Epitalonvial (aim against the glass wall to avoid foaming).

4)Let the powder dissolve gently, do not shake. Swirl lightly if needed.

5)Store the reconstituted vial in the fridge
When in freeze dried form;

Room temp- 3 weeks

Refrigerated – 48 months+

Freezer – 48 months+


When reconstituted;

Refrigerated - 20-30 days

Freezer – 3 to 12 months
Epitalon should be injected twice a day, once in the morning and again at night. You should take 5 mg a day and should be cycled for 20 days every 3 months for best results
Do it once every 3 months and you should be good. If you don’t like the 20 day 5 mg cycle you could always switch to a 10 mg 10 day cycle but whatever works for you
No question everyone should be cycling Epitalon. If you consider yourself a looksmaxxer and don’t cycle Epitalon from now on you’re doing yourself a disservice.

@FlotPSL @Zagro @MaracasMogs
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