I cant think of anything more enraging than those who reply to @vermilioncore , @thompsonz and @frendly fairy threads

[HOLYFUARK]

How retarded can you be to actually read and reply to their threads?

They havent shared a single piece of useful information , all of their threads are bales and shitposts carefully elaborated by their dopamine deprived minds while mashing their cum and grease stained fingers on the keyboard the whole day.

@Thompsonz was born in the elephant foot (chernobyl) at a very young age , his profile is a testament to all the successful careers he partake in a matter of months

Sins vs Thompirla mogbattle of the century






@Vermilioncore apparently can use metamorphosis , sometimes he s an inel piece of shit

And sometimes a chad piece of shit

Last but not least the abused son @frendly who is pitymaxxing on the forum by narrating how his father tortures and forces him to feed the unicorns in his backyard . His female relatives walk naked in the house and inspect his penis.

And there are people who actually believe these guys

All in all they could land a job very easily

MIRIN DISNEY.ORG

 

[Lihito]

god i hate this fucking goof faucci

 

[Incellectually_Shy]

They havent shared a single piece of useful information , all of their threads are bales and shitposts carefully elaborated by their dopamine deprived minds while mashing their cum and grease stained fingers on the keyboard the whole day.

I'm not in a state to start a meaningful discussion. TCF4 excerpts are the best I can offer you...Yes?

 

[Deleted member 13332]

nigga you take this shit way too serious

 

[Deleted member 13332]

@Vermilioncore @ropemax

 

[HOLYFUARK]

nigga you take this shit way too serious

 

[Deleted member 17525]

I'm not here for "useful information" nigger

 

[Deleted member 13332]

View attachment 1632884

what you made me laugh nigga

are u really retarted or what

 

[Incellectually_Shy]

Methylphenidate and atomoxetine enhance sensory-evoked neuronal activity in the visual thalamus of male rats​

Although six weeks of treatment with MPH significantly reduced symptomatology as well as improved daily life functioning in our patients, it neither significantly affected PPI, P50 suppression nor sensitization, but habituation unexpectedly decreased. The absence of PPI and P50 suppression deficits in our patients in the psychostimulant-naïve state indicates no gating deficits. In turn, this suggests that the difficulties to inhibit distraction of attention by irrelevant stimuli that many patients with (adult) ADHD report, have a different origin than the theoretical causes of sensory overload frequently reported in studies on patients with schizophrenia.

Yes...however, we are referring to ASD, not ADHD.

Given the ability of MPH and ATX to improve cognitive performance in humans and rodent assays of attention, we were interested in their influence on early sensory processing in the dorsal lateral geniculate nucleus (dLGN), the primary thalamic relay for visual information from the retina to the visual cortex. In male rats, dLGN neuronal responses to light stimuli were altered in multiple ways after doses of MPH or ATX observed to enhance performance in visually guided assays of attention (MPH = 2 mg/kg; ATX = 0.5 mg/kg). Latencies to response onset and to the peak of the primary response were decreased, while the peak intensity and area of the primary response were increased. In addition, some cells that were unresponsive to light stimuli prior to drug treatment displayed a "gating effect," wherein prominent responses to light stimuli were evident after drug administration. Our results begin to reveal unique effects of MPH and ATX in enhancing sensory signal transmission through visual circuitry, and may yield new insights for understanding the pathophysiology of certain cognitive disorders and inform development of improved therapeutic treatments for these conditions.

My form of ASD:

Cognitive and sensorimotor gating impairments in transgenic mice overexpressing the schizophrenia susceptibility gene Tcf4 in the brain​

Background: The combined analysis of several large genome-wide association studies identified the basic helix-loop-helix (bHLH) transcription factor TCF4 as one of the most significant schizophrenia susceptibility genes. Its function in the adult brain, however, is not known. TCF4 belongs to the E-protein subfamily known to be involved in neurodevelopment. The messenger RNA expression of Tcf4 is sustained in the adult mouse brain, suggesting a function in the adult nervous system. Tcf4 null mutant mice die perinatally, and haploinsufficiency of TCF4 in humans causes severe mental retardation.

Methods: To investigate the possible function of TCF4 in the adult central nervous system, we generated transgenic mice that moderately overexpress TCF4 postnatally in the brain to reduce the risk of developmental effects possibly interfering with adult brain functions. Tcf4 transgenic mice were characterized with molecular, histological, and behavioral methods.

Results: Tcf4 transgenic mice display profound deficits in contextual and cued fear conditioning and sensorimotor gating. Furthermore, we show that TCF4 interacts with the neurogenic bHLH factors NEUROD and NDRF in vivo. Molecular analyses revealed the dynamic circadian deregulation of neuronal bHLH factors in the adult hippocampus.

Conclusions: We conclude that TCF4 likely acts in concert with other neuronal bHLH transcription factors contributing to higher-order cognitive processing. Moderate transcriptional deregulation of Tcf4 in the brain interferes with cognitive functions and might alter circadian processes in mice. These observations provide insight for the first time into the physiological function of TCF4 in the adult brain and its possible contributions to neuropsychiatric disease conditions.

Theoretically, the effect of MPH should help my condition, if it is indeed partially the result of sensorimotor deficits from ASD.

 

[ropemax]

they are all medically retarded

 

[HOLYFUARK]

nigga you take this shit way too serious

what you made me laugh nigga

 

[Deleted member 18819]

@Thompsonz is white.

Problem?

 

[Deleted member 13332]

what?

 

[Vermilioncore]