sigmablud42069
6'1 14
- Joined
- Feb 25, 2026
- Posts
- 576
- Reputation
- 503
IGF-1 or (insulin like growth factor 1) is often takeld about and used as a “muscle building peptide”, while there is evidence of it increasing skeletal muscle tissue via many pathways, increasing muscle satellite cells, increasing NO in your muscles and other anabolic effects. i haven’t heard of it being used for insulin sensitivity. It is mainly used in literature for IGF-1 deficient kids. But there are many studies showing that it effectively increases insulin sensitivity in HIV and diabetes type 2 people. It was proposed as a “cure” to diabetes type 2. I would definitely use IGF-1 over something like berberine or metformin as it could definitely have some muscle growth promoting effects so why not. I would even use it over GLPs unless your a fat fuck as IGF-1 also showed some lipolitic effects. I’d prolly wouldn’t use IGF-1 LR3 as the binding protein also were a part of the insulin sensitivity increasing effect so increlex only.
Could be useful synergistically with HGH as HGH reduces insulin senstivty. That use was actually suggested in a study I read
I can show the studies and explain the proposed mechanisms it but cbf
Could be useful synergistically with HGH as HGH reduces insulin senstivty. That use was actually suggested in a study I read
I can show the studies and explain the proposed mechanisms it but cbf