T
TriFFF
Iron
- Joined
- Oct 23, 2025
- Posts
- 4
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- 3
Igf1lr3 is so fucking ass. And it’s not even just bc of the igfbps
Because if it’s systemic nature and day long half life, it is constantly activating receptors.
Igf1 receptors are incredibly sensitive and send negative feedback loops to the pituitary very quickly. So, within the same day you pin lr3, you’re no longer producing more than half the growth you made before. And in 3 days you may aswel have none at all.
But doesn’t that mean we can just permablast above baseline? No.
Igf1 receptors desensitise insanely fast. This is why gh is kinda only made at night whilst asleep- when your awake the receptors recalibrate.
But lr3 shits in the face of this and just tanks the receptor sense, making every milligram worth a microgram by one week.
Ts is why short acting ghrps mog the fuck out of day long peptides. Fuck mk, fuck Cjc with DAC, and FUCK LR3.
Yuh I used a bunch of hyperbole but whatever
Because if it’s systemic nature and day long half life, it is constantly activating receptors.
Igf1 receptors are incredibly sensitive and send negative feedback loops to the pituitary very quickly. So, within the same day you pin lr3, you’re no longer producing more than half the growth you made before. And in 3 days you may aswel have none at all.
But doesn’t that mean we can just permablast above baseline? No.
Igf1 receptors desensitise insanely fast. This is why gh is kinda only made at night whilst asleep- when your awake the receptors recalibrate.
But lr3 shits in the face of this and just tanks the receptor sense, making every milligram worth a microgram by one week.
Ts is why short acting ghrps mog the fuck out of day long peptides. Fuck mk, fuck Cjc with DAC, and FUCK LR3.
Yuh I used a bunch of hyperbole but whatever