D
Deleted member 4946
Diamond
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thought the same for a long time. But ever since I came across drugs-forum.com I've been exposed to a bunch of super-intelligent dudes who know a lot on pharmacology and pharmacokinetics. After long-drawn-out exposure to antagonists, receptors eventually downregulate instead of upregulating. The fact that that strike cunt JFL'd at this post thinking he btfo'd me is comical.

Pharmacokinetics and safety after once and twice a day doses of meclizine hydrochloride administered to children with achondroplasia
Achondroplasia (ACH) is the most common short-limbed skeletal dysplasia caused by activating mutations in the fibroblast growth factor receptor 3 (FGFR3) gene. We identified that meclizine hydrochloride inhibited FGFR3 signaling in various chondrocytic ...

'Oral administration of meclizine once a day or twice a day seemed to be safe and well tolerated with no serious adverse events in ACH children'
Case closed, move onto your next cope