Insulin Thread: A Complete Guide to Bodybuilding Use

Punjabi Waffen

Punjabi Waffen

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Insulin Thread:
A Complete Guide to Bodybuilding Use


14693


What This Guide Covers

This is a step by step walkthrough for roiders interested in insulin use. We will cover what insulin is, why bodybuilders use it, the different types, dosing, safety measures, diet requirements, side effects, and everything you need to know before using this compound.

small continuation of
Thread 'The MOST Underrated Bodybuilding Compound - An Introduction to Insulin' https://looksmax.org/threads/the-mo...-compound-an-introduction-to-insulin.1913581/


14693


What Is Insulin and Why Bodybuilders Use It

14684


Insulin is a hormone produced by your pancreas. Its main job is to regulate blood sugar by moving glucose from your blood into your cells. Without insulin your cells starve even when your blood is full of sugar. This is what happens in Type 1 diabetes.

But here is why bodybuilders care about
it. Insulin is one of the most anabolic hormones in the human body. It drives nutrients into muscle cells


Protein
carbs
creatine
amino acids


Everything your muscles need to grow. It also suppresses muscle breakdown which means it is anti catabolic too.

The anabolic potential of insulin has been recognized since it was first used for diabetes treatment. It exerts these effects by increasing the transport of glucose and amino acids into skeletal muscle fibers, thereby increasing protein synthesis and decreasing protein degradation. Insulin binds to its receptor, causing phosphorylation of insulin receptor substrate proteins, which activates the PI3K/Akt pathway. This pathway is a key mediator contributing to muscle protein synthesis and can be activated by growth factor signaling such as insulin and IGF1.

Now here is the thing about protein synthesis.

Research shows that insulin at normal physiological levels
does not actually stimulate muscle protein synthesis directly in healthy humans in the postabsorptive state.
What it does is


suppress muscle protein breakdown

achieves muscle protein anabolism by inhibiting muscle protein breakdown


not by ramping up synthesis.

However, when amino acid levels are elevated, such as after a protein rich meal, insulin can stimulate muscle protein synthesis as long as it concomitantly increases muscle blood flow and amino acid delivery. This is why the meal timing and carb loading around insulin use is so critical. You need those amino acids present for insulin to do its anabolic work.

Bodybuilders also use insulin because it creates insane muscle pumps. Your muscles look fuller and rounder because glycogen and water are forced into the cells. This is why competitors use it before shows. It also directs where your calories go.

With insulin, more calories go to muscle and fewer go to fat.
This assumes your diet is clean and your training is intense

if you eat like garbage, insulin will store everything as fat.

Insulin also amplifies the effects of growth hormone and IGF1. Many advanced bodybuilders stack all three for maximum growth. The combination is called


the holy trinity of bodybuilding

GH raises blood sugar
Insulin lowers it.

They balance each other.

GH increases IGF1 production
Insulin drives IGF1 into cells



14693


Types of Insulin

Not all insulin is the same

Different types have different onset times, peaks, and durations. Bodybuilders primarily use fast acting insulins because they are predictable and controllable.



14686


Humalog (insulin lispro)
is the most popular choice for bodybuilders.

Onset is 15 minutes

Peak is 30 to 90 minutes
Duration is 3 to 5 hours


Fast onset
manageable duration
predictable.



Novolog (insulin aspart)
very similar to Humalog

Onset is 10 to 20 minutes

Peak is 1 to 3 hours
Duration is 3 to 5 hours


Some users report slightly faster onset.
If Humalog is not available
Novolog is a direct substitute.

Apidra (insulin glulisine)
the fastest rapid acting insulin.

Onset is 10 to 15 minutes

Peak is 1 to 2 hours
Duration is 3 to 5 hours


Good for pre workout use when you want the fastest possible nutrient delivery.

Humulin R (regular insulin)

old school

Onset is 30 minutes
Peak is 2 to 4 hours
Duration is 5 to 8 hours


Slower than the analogs above. Some old school bodybuilders still prefer it. Requires more planning because the window is longer. If you use Humulin R you need to be eating carbs for a longer period.

Lantus (insulin glargine)
long acting basal insulin.


Onset is 1 to 2 hours
No verified peak
Duration is 20 to 24 hours


Some bodybuilders use it for background anabolism throughout the day.

Much harder to control and higher risk of nocturnal hypoglycemia

I do not recommend this for beginners



NPH (intermediate acting)

has an onset of 1 to 2 hours

peak of 4 to 8 hours
and a duration of 12 to 18 hours


Not commonly used in bodybuilding. Unpredictable peak makes dosing difficult.

Avoid this.

If you are starting out, use Humalog or Novolog. They are fast, predictable, and forgiving.

Avoid NPH until you have extensive experience.

and just avoid Lantus entirely unless you have a medical reason.


14693



Dosing Protocols

Never start high.


14688


2 to 4 IU is the standard beginner dose.
some other people on other bodybuilding forums recommend
starting at 1 IU to assess sensitivity, but theyre just pussies:lul:

You can always increase

users with some experience typically run 5 to 10 IU per injection.

Advanced users go 10 to 20 IU.


Elite professionals use 20 to 40 plus IU per injection

Higher doses require
more carbs
more monitoring
more experience

Do not jump to high doses because you read chad does it. Chad has teams of doctors slaves and coaches monitoring him around the clock.

You probably do not becuase youre subhuman and no one wants to be your coach nor doctor yet alone a slave

The most common timing protocol is pre workout.

You inject 15 to 20 minutes before training.

Then you consume 10 grams of carbs per IU of insulin within 15 minutes of injection.

You train for 60 to 90 minutes.

Then you consume another 10 grams of carbs per IU immediately post workout.

Then you eat a full meal 60 to 90 minutes post workout.


So if you use 5 IU Humalog pre workout, that is 50 grams carbs pre, 50 grams carbs post, then a full meal.

Some people prefer post workout protocol

Inject immediately after training. Consume 10 grams of carbs per IU right away.
Eat a full meal 30 to 60 minutes later.


This is simpler because you are already at the gym and your post workout shake is ready.

Intra workout protocol

injecting at the start of training and sipping a carb drink throughout the workout at 10 grams carbs per IU.

Then eating a full meal immediately after.


This works well if you have a long training session and want constant nutrient delivery.

Advanced users sometimes do multiple daily injections.

Morning, pre workout, post workout, before bed.

This keeps insulin levels elevated throughout the day.

Much higher risk.


The Lantus protocol

injecting once daily in the morning at 10 to 30 IU depending on body weight and experience.

You eat consistent meals every 3 to 4 hours.

You monitor blood glucose constantly.

You have fast carbs available at all times.

Again, I do not recommend this. The risk of nocturnal hypoglycemia is too high,


INB4 slin is safe muh self administer

i dont care you little jeet i want you to reduce the harm


14693


Diet and Carb Requirements

14690


Insulin without carbs is a death sentence. You must eat enough carbs to match your insulin dose. This is the number one rule. Break this rule and you will end up in the hospital or worse.

Start with
10 grams of carbs per IU of insulin.


This is the conservative baseline.

Some users need more. Some need less.
You figure this out through blood glucose monitoring.

Never guess. Always test.

Always have fast acting carbs within arm's reach when insulin is active.

Glucose tablets are 4 grams each and have the fastest absorption.

Fruit juice is 20 to 30 grams per cup.


Honey is 17 grams per tablespoon.

Candy like Skittles or gummy bears works.

Regular soda like Coke or Sprite is 40 grams per can.

Your pre workout meal should be complex carbs, protein, and moderate fat.

Intra workout should be simple carbs only.
Dextrose, maltodextrin, or cyclic dextrin.

Post workout should be fast carbs plus protein.
Whey isolate, white rice, potatoes.

Then your follow up meal should be complex carbs, protein, and if you can handle them, vegetables.

Insulin drives amino acids into muscle cells too.

Aim for 1 to 2 grams of protein per pound of bodyweight daily.
Spread across 5 to 6 meals.


Whey isolate post workout is ideal because it digests fast and gets those amino acids into your bloodstream when insulin is peaking.

Keep fat low around insulin injections.

Fat slows carb absorption and makes timing unpredictable.

Keep pre and post workout meals low fat.

Higher fat meals are fine when insulin is not active.

This is why you see bodybuilders eating egg whites and chicken breast around workouts but steak and nuts later in the day.


14693


Blood Glucose Monitoring

This is non negotiable.

You must monitor your blood glucose every time you use insulin.
No exceptions.
Not once in a while.

Every
single
time.


You need a glucometer.

Any pharmacy brand works.
OneTouch, AccuChek, Contour.


14692


Buy test strips in bulk. You will use many. You also need lancets for finger pricks.

Test before injection to get your baseline.

Test 15 minutes after injection

Test 30 minutes after injection

Test every 30 minutes during insulin activity

Test before bed if insulin was used within 4 hours


This sounds like a lot. It is.
But it is what keeps you alive.

i dont want you dying on me


Normal fasting blood glucose is 70 to 100 mg/dL.
Post meal should be under 140 mg/dL.


On insulin, never let yourself drop below 70 mg/dL.

Hypoglycemia is the main danger.

shakiness
sweating
confusion
rapid heartbeat
hunger
irritability
blurred vision
dizziness.

Below 50 mg/dL you can lose consciousness.


Below 40 mg/dL you can have seizures or die.

I am not exaggerating, on chinas soul

Hyperglycemia is less immediately dangerous but causes long term damage.

excessive thirst
frequent urination
fatigue
blurred vision.


If your blood sugar drops, consume 15 to 20 grams of fast carbs immediately.

Wait 15 minutes. Retest.


If still below 70, consume another 15 to 20 grams. Repeat until blood glucose is above 80.

Then eat a balanced meal once stable.


If you pass out, whoever is with you needs to call emergency services.

If they have glucagon, they should administer it.


14693



Safety Rules

Rule 1, Never use insulin alone. Always have someone nearby (wouldnt reccomend girlfriend if you have one) who knows you are using it and what to do if you pass out. Tell them where your glucose tablets are. Show them how to use your glucometer.

Rule 2. Fast carbs within reach everywhere. Glucose tablets in your pocket. Juice in your gym bag. Candy on your nightstand. Everywhere insulin is active, fast carbs must be within 30 seconds reach.

Rule 3. Start low. 2 to 4 IU maximum for your first time. Do not increase until you have used that dose multiple times without issues. Increase by 1 to 2 IU at a time. Not 5 or 10.

Rule 4. No alcohol. Alcohol lowers blood sugar.
Combining with insulin is extremely dangerous. Do not drink on insulin days.

Rule 5. Test before bed.
If insulin was active within 4 hours of bedtime, test your blood glucose before sleeping. If it is below 100, eat a slow carb snack like oatmeal or toast with peanut butter. This prevents nocturnal hypoglycemia. Dying in your sleep is very bad.


Rule 6. Know your insulin duration. Humalog and Novolog last 3 to 5 hours. Do not inject again until at least 5 hours have passed unless you are an advanced user with constant monitoring.

Rule 7. Do not skip meals, you anorexic bitch.
If you inject insulin,
you must eat. No exceptions. Even if you are not hungry. Even if you feel sick. The insulin will drop your blood sugar regardless.



14693


Side Effects and Risks

Hypoglycemia is the number one risk.

seizures
brain damage
coma
death


Most insulin related deaths in bodybuilding are from hypoglycemia, not long term complications. This happens when someone miscalculates carbs, skips a meal, or trains harder than expected and burns through glucose too fast.


Insulin resistance is the long term danger.

Chronic high dose insulin use can make your body resistant to its own insulin.

This leads to Type 2 diabetes.

Risk increases with


dose
duration
bf%


Constant physical exercise prevents insulin resistance in the short term. But the long term effects of repeated insulin abuse are not fully understood.

Stay lean mothafuckaaaa
Cycle insulin
Do not use year round, youre not pro


Water retention happens to everyone.
Insulin causes subcutaneous water retention, You look puffy and bloated.

This is temporary

Some bodybuilders use diuretics before shows to shed water

Gyno can occur because insulin can increase estrogen indirectly by raising IGF1 and promoting aromatization.
if you are prone to gyno, monitor for lump formation and use an aromatase inhibitor if needed.

Insulin promotes fat storage in arteries and increases inflammation

Lipohypertrophy
repeated injections in the same spot cause fat lumps under the skin.

"Research confirms that repeated insulin injection without site rotation increases skin thickness and causes subcutaneous nodules."

These lumps can alter insulin absorption and make dosing unpredictable.

Rotate injection sites

Abdomen
thighs
deltoids

dem as cheeks

Do not inject into lumps.


14693


Stacking and Synergy

Insulin plus GH is the classic stack.

as said before

GH raises blood sugar.
Insulin lowers it.
They balance each other.

Time insulin around meals and workouts.

Insulin plus IGF1 LR3 is even more potent.

IGF1 LR3 is a synthetic version of insulin like growth factor 1.
It directly stimulates muscle growth.
Combined with insulin,
the effect is amplified.

IGF1 can cause gut growth and organ enlargement. You do not want a distended abdomen.

Insulin plus anabolic steroids is the standard.
Test, tren, bold,
and other AAS
increase protein synthesis.

Insulin increases nutrient delivery.


Together they create the perfect nectar given by gods for muscle growth.




Insulin plus metformin is also pretty good, for health.

Metformin improves insulin sensitivity, Some users take metformin on off days to keep their natural insulin response sharp.
Dose 500 to 1000mg daily.


Not mandatory but helpful for long term health.



14693


Injection Technique


Insulin syringes are 1cc capacity, 29 to 31 gauge, half inch length.

These are tiny needles. Almost painless.

If you use insulin pens, 4mm to 8mm pen needles are even smaller and more convenient.

The abdomen is the standard site.

Fastest absorption

Avoid the exact center, so rotate it.


Clean the site with alcohol and let it dry.

Pinch a fold of skin.

Insert the needle at 90 degrees.

Inject slowly.

Hold for 5 to 10 seconds before withdrawing.

Do not rub the site after.

This can alter absorption speed.

Unopened insulin should be refrigerated at 2 to 8 degrees Celsius. Do not freeze.
Opened insulin can stay at room temperature for 28 days. Keep away from heat and sunlight.


14693


Cycling and Duration


Most bodybuilders use insulin in cycles of 4 to 8 weeks.
Some extend to 12 weeks.

Year round use is retarded and leads to insulin resistance.

Take equal or longer time off.

8 weeks on, 8 to 12 weeks off.

Use the off time to restore insulin sensitivity. Metformin and berberine help during off periods.

Use insulin primarily during bulking phases
The extra calories and insulin create maximum growth


Do not use insulin during cutting, the risk of hypoglycemia is higher in a calorie deficit.

Your body has less glucose to work with.

Do not use insulin if you have a history of hypoglycemia

Do not use if you have diabetes or prediabetes

Do not use if you cannot commit to strict diet and monitoring



14693


Pain Management and Ancillary

This covers drugs that can help with recovery, side effects, and overall experience while using insulin.

Not all of these are necessary. Pick what applies to your situation.

Ibuprofen and Acetaminophen
OTC pain reliefer


Useful for injection site soreness training related joint pain
general aches


ibu 400 to 600mg every 6 hours.
Aceta 500 to 1000mg every 6 hours

Do not exceed 3200mg ibuprofen
nor
4000mg acetaminophen daily



Aromatase Inhibitors

If you are running test or other aromatizing steroids alongside insulin

Arimidex (anastrozole)
0.5mg EOD

Aromasin (exemestane) at 12.5mg EOD


Blood work confirms need.

Do not crash your estrogen.

You need it for joint health and mood
.

Cabergoline
If you are using nandrolone or tren,
prolactin can rise.

High prolactin causes gyno, sexual dysfunction, and mood issues.

Cabergoline 0.25mg twice weekly

Nolvadex (tamoxifen)

SERM
Used for gyno reversal

20mg daily

Liver Support

If using oral steroids alongside insulin, protect your liver.
TUDCA 250 to 500mg daily
NAC at 600 to 1200mg daily.


Cardiovascular support

Insulin and AAS both strain your heart.
Fish oil 3 to 6 grams daily for triglycerides
CoQ10 at 100 to 200mg daily for heart energy
Citrus bergamot for cholesterol support
Garlic extract for blood pressure

Sleep Aids
Melatonin
3 to 10mg before bed Magnesium glycinate 400mg before bed

Digestive Enzymes
Betaine HCl
with protein meals. Pancreatic enzymes with large meals. Probiotics daily for gut health.



References

Chow LS et al. Mechanism of insulin's anabolic effect on muscle: measurements of muscle protein synthesis and breakdown using aminoacyl-tRNA and other surrogate measures. Am J Physiol Endocrinol Metab.



Fujita S et al. Effect of insulin on human skeletal muscle protein synthesis is modulated by insulin induced changes in muscle blood flow and amino acid availability.



Sato T et al. Insulin does not stimulate muscle protein synthesis during increased plasma branched chain amino acids alone but still decreases whole body proteolysis in humans. Diabetes Metab Res Rev. 2017 Jan;33(1).


Sagoe D et al. The global epidemiology of AAs steroid use: a meta analysis and meta-regression analysis.



Maccarinelli G et al. Metabolic Consequences of Anabolic Steroids, Insulin, and Growth Hormone Abuse in Recreational Bodybuilders. J Clin Med. 2024



Kamei R et al. Repeated insulin injection without site rotation affects skin thickness.



Elrefaey NM et al. Ameliorating Insulin Injection Site Rotation and its Impact on Lipohypertrophy Incidence and Glycemic Control.

 

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Insulin Thread:
A Complete Guide to Bodybuilding Use


View attachment 5308513

What This Guide Covers

This is a step by step walkthrough for roiders interested in insulin use. We will cover what insulin is, why bodybuilders use it, the different types, dosing, safety measures, diet requirements, side effects, and everything you need to know before using this compound.

small continuation of
Thread 'The MOST Underrated Bodybuilding Compound - An Introduction to Insulin' https://looksmax.org/threads/the-mo...-compound-an-introduction-to-insulin.1913581/


View attachment 5308513

What Is Insulin and Why Bodybuilders Use It

View attachment 5308499

Insulin is a hormone produced by your pancreas. Its main job is to regulate blood sugar by moving glucose from your blood into your cells. Without insulin your cells starve even when your blood is full of sugar. This is what happens in Type 1 diabetes.

But here is why bodybuilders care about
it. Insulin is one of the most anabolic hormones in the human body. It drives nutrients into muscle cells


Protein
carbs
creatine
amino acids


Everything your muscles need to grow. It also suppresses muscle breakdown which means it is anti catabolic too.

The anabolic potential of insulin has been recognized since it was first used for diabetes treatment. It exerts these effects by increasing the transport of glucose and amino acids into skeletal muscle fibers, thereby increasing protein synthesis and decreasing protein degradation. Insulin binds to its receptor, causing phosphorylation of insulin receptor substrate proteins, which activates the PI3K/Akt pathway. This pathway is a key mediator contributing to muscle protein synthesis and can be activated by growth factor signaling such as insulin and IGF1.

Now here is the thing about protein synthesis.

Research shows that insulin at normal physiological levels
does not actually stimulate muscle protein synthesis directly in healthy humans in the postabsorptive state.
What it does is


suppress muscle protein breakdown

achieves muscle protein anabolism by inhibiting muscle protein breakdown


not by ramping up synthesis.

However, when amino acid levels are elevated, such as after a protein rich meal, insulin can stimulate muscle protein synthesis as long as it concomitantly increases muscle blood flow and amino acid delivery. This is why the meal timing and carb loading around insulin use is so critical. You need those amino acids present for insulin to do its anabolic work.

Bodybuilders also use insulin because it creates insane muscle pumps. Your muscles look fuller and rounder because glycogen and water are forced into the cells. This is why competitors use it before shows. It also directs where your calories go.

With insulin, more calories go to muscle and fewer go to fat.
This assumes your diet is clean and your training is intense

if you eat like garbage, insulin will store everything as fat.

Insulin also amplifies the effects of growth hormone and IGF1. Many advanced bodybuilders stack all three for maximum growth. The combination is called


the holy trinity of bodybuilding

GH raises blood sugar
Insulin lowers it.

They balance each other.

GH increases IGF1 production
Insulin drives IGF1 into cells



View attachment 5308513

Types of Insulin

Not all insulin is the same

Different types have different onset times, peaks, and durations. Bodybuilders primarily use fast acting insulins because they are predictable and controllable.



View attachment 5308463

Humalog (insulin lispro)
is the most popular choice for bodybuilders.

Onset is 15 minutes

Peak is 30 to 90 minutes
Duration is 3 to 5 hours


Fast onset
manageable duration
predictable.



Novolog (insulin aspart)
very similar to Humalog

Onset is 10 to 20 minutes

Peak is 1 to 3 hours
Duration is 3 to 5 hours


Some users report slightly faster onset.
If Humalog is not available
Novolog is a direct substitute.

Apidra (insulin glulisine)
the fastest rapid acting insulin.

Onset is 10 to 15 minutes

Peak is 1 to 2 hours
Duration is 3 to 5 hours


Good for pre workout use when you want the fastest possible nutrient delivery.

Humulin R (regular insulin)

old school

Onset is 30 minutes
Peak is 2 to 4 hours
Duration is 5 to 8 hours


Slower than the analogs above. Some old school bodybuilders still prefer it. Requires more planning because the window is longer. If you use Humulin R you need to be eating carbs for a longer period.

Lantus (insulin glargine)
long acting basal insulin.


Onset is 1 to 2 hours
No verified peak
Duration is 20 to 24 hours


Some bodybuilders use it for background anabolism throughout the day.

Much harder to control and higher risk of nocturnal hypoglycemia

I do not recommend this for beginners



NPH (intermediate acting)

has an onset of 1 to 2 hours

peak of 4 to 8 hours
and a duration of 12 to 18 hours


Not commonly used in bodybuilding. Unpredictable peak makes dosing difficult.

Avoid this.

If you are starting out, use Humalog or Novolog. They are fast, predictable, and forgiving.

Avoid NPH until you have extensive experience.

and just avoid Lantus entirely unless you have a medical reason.


View attachment 5308513


Dosing Protocols

Never start high.


View attachment 5308474

2 to 4 IU is the standard beginner dose.
some other people on other bodybuilding forums recommend
starting at 1 IU to assess sensitivity, but theyre just pussies:lul:

You can always increase

users with some experience typically run 5 to 10 IU per injection.

Advanced users go 10 to 20 IU.


Elite professionals use 20 to 40 plus IU per injection

Higher doses require
more carbs
more monitoring
more experience

Do not jump to high doses because you read chad does it. Chad has teams of doctors slaves and coaches monitoring him around the clock.

You probably do not becuase youre subhuman and no one wants to be your coach nor doctor yet alone a slave

The most common timing protocol is pre workout.

You inject 15 to 20 minutes before training.

Then you consume 10 grams of carbs per IU of insulin within 15 minutes of injection.

You train for 60 to 90 minutes.

Then you consume another 10 grams of carbs per IU immediately post workout.

Then you eat a full meal 60 to 90 minutes post workout.


So if you use 5 IU Humalog pre workout, that is 50 grams carbs pre, 50 grams carbs post, then a full meal.

Some people prefer post workout protocol

Inject immediately after training. Consume 10 grams of carbs per IU right away.
Eat a full meal 30 to 60 minutes later.


This is simpler because you are already at the gym and your post workout shake is ready.

Intra workout protocol

injecting at the start of training and sipping a carb drink throughout the workout at 10 grams carbs per IU.

Then eating a full meal immediately after.


This works well if you have a long training session and want constant nutrient delivery.

Advanced users sometimes do multiple daily injections.

Morning, pre workout, post workout, before bed.

This keeps insulin levels elevated throughout the day.

Much higher risk.


The Lantus protocol

injecting once daily in the morning at 10 to 30 IU depending on body weight and experience.

You eat consistent meals every 3 to 4 hours.

You monitor blood glucose constantly.

You have fast carbs available at all times.

Again, I do not recommend this. The risk of nocturnal hypoglycemia is too high,


INB4 slin is safe muh self administer

i dont care you little jeet i want you to reduce the harm


View attachment 5308513

Diet and Carb Requirements

View attachment 5308489

Insulin without carbs is a death sentence. You must eat enough carbs to match your insulin dose. This is the number one rule. Break this rule and you will end up in the hospital or worse.

Start with
10 grams of carbs per IU of insulin.


This is the conservative baseline.

Some users need more. Some need less.
You figure this out through blood glucose monitoring.

Never guess. Always test.

Always have fast acting carbs within arm's reach when insulin is active.

Glucose tablets are 4 grams each and have the fastest absorption.

Fruit juice is 20 to 30 grams per cup.


Honey is 17 grams per tablespoon.

Candy like Skittles or gummy bears works.

Regular soda like Coke or Sprite is 40 grams per can.

Your pre workout meal should be complex carbs, protein, and moderate fat.

Intra workout should be simple carbs only.
Dextrose, maltodextrin, or cyclic dextrin.

Post workout should be fast carbs plus protein.
Whey isolate, white rice, potatoes.

Then your follow up meal should be complex carbs, protein, and if you can handle them, vegetables.

Insulin drives amino acids into muscle cells too.

Aim for 1 to 2 grams of protein per pound of bodyweight daily.
Spread across 5 to 6 meals.


Whey isolate post workout is ideal because it digests fast and gets those amino acids into your bloodstream when insulin is peaking.

Keep fat low around insulin injections.

Fat slows carb absorption and makes timing unpredictable.

Keep pre and post workout meals low fat.

Higher fat meals are fine when insulin is not active.

This is why you see bodybuilders eating egg whites and chicken breast around workouts but steak and nuts later in the day.


View attachment 5308513

Blood Glucose Monitoring

This is non negotiable.

You must monitor your blood glucose every time you use insulin.
No exceptions.
Not once in a while.

Every
single
time.


You need a glucometer.

Any pharmacy brand works.
OneTouch, AccuChek, Contour.


View attachment 5308494

Buy test strips in bulk. You will use many. You also need lancets for finger pricks.

Test before injection to get your baseline.

Test 15 minutes after injection

Test 30 minutes after injection

Test every 30 minutes during insulin activity

Test before bed if insulin was used within 4 hours


This sounds like a lot. It is.
But it is what keeps you alive.

i dont want you dying on me


Normal fasting blood glucose is 70 to 100 mg/dL.
Post meal should be under 140 mg/dL.


On insulin, never let yourself drop below 70 mg/dL.

Hypoglycemia is the main danger.

shakiness
sweating
confusion
rapid heartbeat
hunger
irritability
blurred vision
dizziness.

Below 50 mg/dL you can lose consciousness.


Below 40 mg/dL you can have seizures or die.

I am not exaggerating, on chinas soul

Hyperglycemia is less immediately dangerous but causes long term damage.

excessive thirst
frequent urination
fatigue
blurred vision.


If your blood sugar drops, consume 15 to 20 grams of fast carbs immediately.

Wait 15 minutes. Retest.


If still below 70, consume another 15 to 20 grams. Repeat until blood glucose is above 80.

Then eat a balanced meal once stable.


If you pass out, whoever is with you needs to call emergency services.

If they have glucagon, they should administer it.


View attachment 5308513


Safety Rules

Rule 1, Never use insulin alone. Always have someone nearby (wouldnt reccomend girlfriend if you have one) who knows you are using it and what to do if you pass out. Tell them where your glucose tablets are. Show them how to use your glucometer.

Rule 2. Fast carbs within reach everywhere. Glucose tablets in your pocket. Juice in your gym bag. Candy on your nightstand. Everywhere insulin is active, fast carbs must be within 30 seconds reach.

Rule 3. Start low. 2 to 4 IU maximum for your first time. Do not increase until you have used that dose multiple times without issues. Increase by 1 to 2 IU at a time. Not 5 or 10.

Rule 4. No alcohol. Alcohol lowers blood sugar.
Combining with insulin is extremely dangerous. Do not drink on insulin days.

Rule 5. Test before bed.
If insulin was active within 4 hours of bedtime, test your blood glucose before sleeping. If it is below 100, eat a slow carb snack like oatmeal or toast with peanut butter. This prevents nocturnal hypoglycemia. Dying in your sleep is very bad.


Rule 6. Know your insulin duration. Humalog and Novolog last 3 to 5 hours. Do not inject again until at least 5 hours have passed unless you are an advanced user with constant monitoring.

Rule 7. Do not skip meals, you anorexic bitch.
If you inject insulin,
you must eat. No exceptions. Even if you are not hungry. Even if you feel sick. The insulin will drop your blood sugar regardless.



View attachment 5308513

Side Effects and Risks

Hypoglycemia is the number one risk.

seizures
brain damage
coma
death


Most insulin related deaths in bodybuilding are from hypoglycemia, not long term complications. This happens when someone miscalculates carbs, skips a meal, or trains harder than expected and burns through glucose too fast.


Insulin resistance is the long term danger.

Chronic high dose insulin use can make your body resistant to its own insulin.

This leads to Type 2 diabetes.

Risk increases with


dose
duration
bf%


Constant physical exercise prevents insulin resistance in the short term. But the long term effects of repeated insulin abuse are not fully understood.

Stay lean mothafuckaaaa
Cycle insulin
Do not use year round, youre not pro


Water retention happens to everyone.
Insulin causes subcutaneous water retention, You look puffy and bloated.

This is temporary

Some bodybuilders use diuretics before shows to shed water

Gyno can occur because insulin can increase estrogen indirectly by raising IGF1 and promoting aromatization.
if you are prone to gyno, monitor for lump formation and use an aromatase inhibitor if needed.

Insulin promotes fat storage in arteries and increases inflammation

Lipohypertrophy
repeated injections in the same spot cause fat lumps under the skin.



These lumps can alter insulin absorption and make dosing unpredictable.

Rotate injection sites

Abdomen
thighs
deltoids

dem as cheeks

Do not inject into lumps.


View attachment 5308513

Stacking and Synergy

Insulin plus GH is the classic stack.

as said before



Time insulin around meals and workouts.

Insulin plus IGF1 LR3 is even more potent.

IGF1 LR3 is a synthetic version of insulin like growth factor 1.
It directly stimulates muscle growth.
Combined with insulin,
the effect is amplified.

IGF1 can cause gut growth and organ enlargement. You do not want a distended abdomen.

Insulin plus anabolic steroids is the standard.
Test, tren, bold,
and other AAS
increase protein synthesis.

Insulin increases nutrient delivery.


Together they create the perfect nectar given by gods for muscle growth.




Insulin plus metformin is also pretty good, for health.

Metformin improves insulin sensitivity, Some users take metformin on off days to keep their natural insulin response sharp.
Dose 500 to 1000mg daily.


Not mandatory but helpful for long term health.



View attachment 5308513

Injection Technique


Insulin syringes are 1cc capacity, 29 to 31 gauge, half inch length.

These are tiny needles. Almost painless.

If you use insulin pens, 4mm to 8mm pen needles are even smaller and more convenient.

The abdomen is the standard site.

Fastest absorption

Avoid the exact center, so rotate it.


Clean the site with alcohol and let it dry.

Pinch a fold of skin.

Insert the needle at 90 degrees.

Inject slowly.

Hold for 5 to 10 seconds before withdrawing.

Do not rub the site after.

This can alter absorption speed.

Unopened insulin should be refrigerated at 2 to 8 degrees Celsius. Do not freeze.
Opened insulin can stay at room temperature for 28 days. Keep away from heat and sunlight.


View attachment 5308513

Cycling and Duration


Most bodybuilders use insulin in cycles of 4 to 8 weeks.
Some extend to 12 weeks.

Year round use is retarded and leads to insulin resistance.

Take equal or longer time off.

8 weeks on, 8 to 12 weeks off.

Use the off time to restore insulin sensitivity. Metformin and berberine help during off periods.

Use insulin primarily during bulking phases
The extra calories and insulin create maximum growth


Do not use insulin during cutting, the risk of hypoglycemia is higher in a calorie deficit.

Your body has less glucose to work with.

Do not use insulin if you have a history of hypoglycemia

Do not use if you have diabetes or prediabetes

Do not use if you cannot commit to strict diet and monitoring



View attachment 5308513

Pain Management and Ancillary

This covers drugs that can help with recovery, side effects, and overall experience while using insulin.

Not all of these are necessary. Pick what applies to your situation.

Ibuprofen and Acetaminophen
OTC pain reliefer


Useful for injection site soreness training related joint pain
general aches


ibu 400 to 600mg every 6 hours.
Aceta 500 to 1000mg every 6 hours





Aromatase Inhibitors

If you are running test or other aromatizing steroids alongside insulin

Arimidex (anastrozole)
0.5mg EOD

Aromasin (exemestane) at 12.5mg EOD


Blood work confirms need.

Do not crash your estrogen.

You need it for joint health and mood
.

Cabergoline
If you are using nandrolone or tren,
prolactin can rise.

High prolactin causes gyno, sexual dysfunction, and mood issues.

Cabergoline 0.25mg twice weekly

Nolvadex (tamoxifen)

SERM
Used for gyno reversal

20mg daily

Liver Support

If using oral steroids alongside insulin, protect your liver.
TUDCA 250 to 500mg daily
NAC at 600 to 1200mg daily.


Cardiovascular support

Insulin and AAS both strain your heart.
Fish oil 3 to 6 grams daily for triglycerides
CoQ10 at 100 to 200mg daily for heart energy
Citrus bergamot for cholesterol support
Garlic extract for blood pressure

Sleep Aids
Melatonin
3 to 10mg before bed Magnesium glycinate 400mg before bed

Digestive Enzymes
Betaine HCl
with protein meals. Pancreatic enzymes with large meals. Probiotics daily for gut health.



References




https://pubmed.ncbi.nlm.nih.gov/16705065/



https://pmc.ncbi.nlm.nih.gov/articles/PMC2804964/



https://pmc.ncbi.nlm.nih.gov/articles/PMC5241558/




https://pmc.ncbi.nlm.nih.gov/articles/PMC5723243/



https://pmc.ncbi.nlm.nih.gov/articles/PMC10973313/



https://pmc.ncbi.nlm.nih.gov/articles/PMC9153835/



https://www.sciencedirect.com/org/science/article/pii/S0250688224000033




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Insulin Thread:
A Complete Guide to Bodybuilding Use


View attachment 5308513

What This Guide Covers

This is a step by step walkthrough for roiders interested in insulin use. We will cover what insulin is, why bodybuilders use it, the different types, dosing, safety measures, diet requirements, side effects, and everything you need to know before using this compound.

small continuation of
Thread 'The MOST Underrated Bodybuilding Compound - An Introduction to Insulin' https://looksmax.org/threads/the-mo...-compound-an-introduction-to-insulin.1913581/


View attachment 5308513

What Is Insulin and Why Bodybuilders Use It

View attachment 5308499

Insulin is a hormone produced by your pancreas. Its main job is to regulate blood sugar by moving glucose from your blood into your cells. Without insulin your cells starve even when your blood is full of sugar. This is what happens in Type 1 diabetes.

But here is why bodybuilders care about
it. Insulin is one of the most anabolic hormones in the human body. It drives nutrients into muscle cells


Protein
carbs
creatine
amino acids


Everything your muscles need to grow. It also suppresses muscle breakdown which means it is anti catabolic too.

The anabolic potential of insulin has been recognized since it was first used for diabetes treatment. It exerts these effects by increasing the transport of glucose and amino acids into skeletal muscle fibers, thereby increasing protein synthesis and decreasing protein degradation. Insulin binds to its receptor, causing phosphorylation of insulin receptor substrate proteins, which activates the PI3K/Akt pathway. This pathway is a key mediator contributing to muscle protein synthesis and can be activated by growth factor signaling such as insulin and IGF1.

Now here is the thing about protein synthesis.

Research shows that insulin at normal physiological levels
does not actually stimulate muscle protein synthesis directly in healthy humans in the postabsorptive state.
What it does is


suppress muscle protein breakdown

achieves muscle protein anabolism by inhibiting muscle protein breakdown


not by ramping up synthesis.

However, when amino acid levels are elevated, such as after a protein rich meal, insulin can stimulate muscle protein synthesis as long as it concomitantly increases muscle blood flow and amino acid delivery. This is why the meal timing and carb loading around insulin use is so critical. You need those amino acids present for insulin to do its anabolic work.

Bodybuilders also use insulin because it creates insane muscle pumps. Your muscles look fuller and rounder because glycogen and water are forced into the cells. This is why competitors use it before shows. It also directs where your calories go.

With insulin, more calories go to muscle and fewer go to fat.
This assumes your diet is clean and your training is intense

if you eat like garbage, insulin will store everything as fat.

Insulin also amplifies the effects of growth hormone and IGF1. Many advanced bodybuilders stack all three for maximum growth. The combination is called


the holy trinity of bodybuilding

GH raises blood sugar
Insulin lowers it.

They balance each other.

GH increases IGF1 production
Insulin drives IGF1 into cells



View attachment 5308513

Types of Insulin

Not all insulin is the same

Different types have different onset times, peaks, and durations. Bodybuilders primarily use fast acting insulins because they are predictable and controllable.



View attachment 5308463

Humalog (insulin lispro)
is the most popular choice for bodybuilders.

Onset is 15 minutes

Peak is 30 to 90 minutes
Duration is 3 to 5 hours


Fast onset
manageable duration
predictable.



Novolog (insulin aspart)
very similar to Humalog

Onset is 10 to 20 minutes

Peak is 1 to 3 hours
Duration is 3 to 5 hours


Some users report slightly faster onset.
If Humalog is not available
Novolog is a direct substitute.

Apidra (insulin glulisine)
the fastest rapid acting insulin.

Onset is 10 to 15 minutes

Peak is 1 to 2 hours
Duration is 3 to 5 hours


Good for pre workout use when you want the fastest possible nutrient delivery.

Humulin R (regular insulin)

old school

Onset is 30 minutes
Peak is 2 to 4 hours
Duration is 5 to 8 hours


Slower than the analogs above. Some old school bodybuilders still prefer it. Requires more planning because the window is longer. If you use Humulin R you need to be eating carbs for a longer period.

Lantus (insulin glargine)
long acting basal insulin.


Onset is 1 to 2 hours
No verified peak
Duration is 20 to 24 hours


Some bodybuilders use it for background anabolism throughout the day.

Much harder to control and higher risk of nocturnal hypoglycemia

I do not recommend this for beginners



NPH (intermediate acting)

has an onset of 1 to 2 hours

peak of 4 to 8 hours
and a duration of 12 to 18 hours


Not commonly used in bodybuilding. Unpredictable peak makes dosing difficult.

Avoid this.

If you are starting out, use Humalog or Novolog. They are fast, predictable, and forgiving.

Avoid NPH until you have extensive experience.

and just avoid Lantus entirely unless you have a medical reason.


View attachment 5308513


Dosing Protocols

Never start high.


View attachment 5308474

2 to 4 IU is the standard beginner dose.
some other people on other bodybuilding forums recommend
starting at 1 IU to assess sensitivity, but theyre just pussies:lul:

You can always increase

users with some experience typically run 5 to 10 IU per injection.

Advanced users go 10 to 20 IU.


Elite professionals use 20 to 40 plus IU per injection

Higher doses require
more carbs
more monitoring
more experience

Do not jump to high doses because you read chad does it. Chad has teams of doctors slaves and coaches monitoring him around the clock.

You probably do not becuase youre subhuman and no one wants to be your coach nor doctor yet alone a slave

The most common timing protocol is pre workout.

You inject 15 to 20 minutes before training.

Then you consume 10 grams of carbs per IU of insulin within 15 minutes of injection.

You train for 60 to 90 minutes.

Then you consume another 10 grams of carbs per IU immediately post workout.

Then you eat a full meal 60 to 90 minutes post workout.


So if you use 5 IU Humalog pre workout, that is 50 grams carbs pre, 50 grams carbs post, then a full meal.

Some people prefer post workout protocol

Inject immediately after training. Consume 10 grams of carbs per IU right away.
Eat a full meal 30 to 60 minutes later.


This is simpler because you are already at the gym and your post workout shake is ready.

Intra workout protocol

injecting at the start of training and sipping a carb drink throughout the workout at 10 grams carbs per IU.

Then eating a full meal immediately after.


This works well if you have a long training session and want constant nutrient delivery.

Advanced users sometimes do multiple daily injections.

Morning, pre workout, post workout, before bed.

This keeps insulin levels elevated throughout the day.

Much higher risk.


The Lantus protocol

injecting once daily in the morning at 10 to 30 IU depending on body weight and experience.

You eat consistent meals every 3 to 4 hours.

You monitor blood glucose constantly.

You have fast carbs available at all times.

Again, I do not recommend this. The risk of nocturnal hypoglycemia is too high,


INB4 slin is safe muh self administer

i dont care you little jeet i want you to reduce the harm


View attachment 5308513

Diet and Carb Requirements

View attachment 5308489

Insulin without carbs is a death sentence. You must eat enough carbs to match your insulin dose. This is the number one rule. Break this rule and you will end up in the hospital or worse.

Start with
10 grams of carbs per IU of insulin.


This is the conservative baseline.

Some users need more. Some need less.
You figure this out through blood glucose monitoring.

Never guess. Always test.

Always have fast acting carbs within arm's reach when insulin is active.

Glucose tablets are 4 grams each and have the fastest absorption.

Fruit juice is 20 to 30 grams per cup.


Honey is 17 grams per tablespoon.

Candy like Skittles or gummy bears works.

Regular soda like Coke or Sprite is 40 grams per can.

Your pre workout meal should be complex carbs, protein, and moderate fat.

Intra workout should be simple carbs only.
Dextrose, maltodextrin, or cyclic dextrin.

Post workout should be fast carbs plus protein.
Whey isolate, white rice, potatoes.

Then your follow up meal should be complex carbs, protein, and if you can handle them, vegetables.

Insulin drives amino acids into muscle cells too.

Aim for 1 to 2 grams of protein per pound of bodyweight daily.
Spread across 5 to 6 meals.


Whey isolate post workout is ideal because it digests fast and gets those amino acids into your bloodstream when insulin is peaking.

Keep fat low around insulin injections.

Fat slows carb absorption and makes timing unpredictable.

Keep pre and post workout meals low fat.

Higher fat meals are fine when insulin is not active.

This is why you see bodybuilders eating egg whites and chicken breast around workouts but steak and nuts later in the day.


View attachment 5308513

Blood Glucose Monitoring

This is non negotiable.

You must monitor your blood glucose every time you use insulin.
No exceptions.
Not once in a while.

Every
single
time.


You need a glucometer.

Any pharmacy brand works.
OneTouch, AccuChek, Contour.


View attachment 5308494

Buy test strips in bulk. You will use many. You also need lancets for finger pricks.

Test before injection to get your baseline.

Test 15 minutes after injection

Test 30 minutes after injection

Test every 30 minutes during insulin activity

Test before bed if insulin was used within 4 hours


This sounds like a lot. It is.
But it is what keeps you alive.

i dont want you dying on me


Normal fasting blood glucose is 70 to 100 mg/dL.
Post meal should be under 140 mg/dL.


On insulin, never let yourself drop below 70 mg/dL.

Hypoglycemia is the main danger.

shakiness
sweating
confusion
rapid heartbeat
hunger
irritability
blurred vision
dizziness.

Below 50 mg/dL you can lose consciousness.


Below 40 mg/dL you can have seizures or die.

I am not exaggerating, on chinas soul

Hyperglycemia is less immediately dangerous but causes long term damage.

excessive thirst
frequent urination
fatigue
blurred vision.


If your blood sugar drops, consume 15 to 20 grams of fast carbs immediately.

Wait 15 minutes. Retest.


If still below 70, consume another 15 to 20 grams. Repeat until blood glucose is above 80.

Then eat a balanced meal once stable.


If you pass out, whoever is with you needs to call emergency services.

If they have glucagon, they should administer it.


View attachment 5308513


Safety Rules

Rule 1, Never use insulin alone. Always have someone nearby (wouldnt reccomend girlfriend if you have one) who knows you are using it and what to do if you pass out. Tell them where your glucose tablets are. Show them how to use your glucometer.

Rule 2. Fast carbs within reach everywhere. Glucose tablets in your pocket. Juice in your gym bag. Candy on your nightstand. Everywhere insulin is active, fast carbs must be within 30 seconds reach.

Rule 3. Start low. 2 to 4 IU maximum for your first time. Do not increase until you have used that dose multiple times without issues. Increase by 1 to 2 IU at a time. Not 5 or 10.

Rule 4. No alcohol. Alcohol lowers blood sugar.
Combining with insulin is extremely dangerous. Do not drink on insulin days.

Rule 5. Test before bed.
If insulin was active within 4 hours of bedtime, test your blood glucose before sleeping. If it is below 100, eat a slow carb snack like oatmeal or toast with peanut butter. This prevents nocturnal hypoglycemia. Dying in your sleep is very bad.


Rule 6. Know your insulin duration. Humalog and Novolog last 3 to 5 hours. Do not inject again until at least 5 hours have passed unless you are an advanced user with constant monitoring.

Rule 7. Do not skip meals, you anorexic bitch.
If you inject insulin,
you must eat. No exceptions. Even if you are not hungry. Even if you feel sick. The insulin will drop your blood sugar regardless.



View attachment 5308513

Side Effects and Risks

Hypoglycemia is the number one risk.

seizures
brain damage
coma
death


Most insulin related deaths in bodybuilding are from hypoglycemia, not long term complications. This happens when someone miscalculates carbs, skips a meal, or trains harder than expected and burns through glucose too fast.


Insulin resistance is the long term danger.

Chronic high dose insulin use can make your body resistant to its own insulin.

This leads to Type 2 diabetes.

Risk increases with


dose
duration
bf%


Constant physical exercise prevents insulin resistance in the short term. But the long term effects of repeated insulin abuse are not fully understood.

Stay lean mothafuckaaaa
Cycle insulin
Do not use year round, youre not pro


Water retention happens to everyone.
Insulin causes subcutaneous water retention, You look puffy and bloated.

This is temporary

Some bodybuilders use diuretics before shows to shed water

Gyno can occur because insulin can increase estrogen indirectly by raising IGF1 and promoting aromatization.
if you are prone to gyno, monitor for lump formation and use an aromatase inhibitor if needed.

Insulin promotes fat storage in arteries and increases inflammation

Lipohypertrophy
repeated injections in the same spot cause fat lumps under the skin.



These lumps can alter insulin absorption and make dosing unpredictable.

Rotate injection sites

Abdomen
thighs
deltoids

dem as cheeks

Do not inject into lumps.


View attachment 5308513

Stacking and Synergy

Insulin plus GH is the classic stack.

as said before



Time insulin around meals and workouts.

Insulin plus IGF1 LR3 is even more potent.

IGF1 LR3 is a synthetic version of insulin like growth factor 1.
It directly stimulates muscle growth.
Combined with insulin,
the effect is amplified.

IGF1 can cause gut growth and organ enlargement. You do not want a distended abdomen.

Insulin plus anabolic steroids is the standard.
Test, tren, bold,
and other AAS
increase protein synthesis.

Insulin increases nutrient delivery.


Together they create the perfect nectar given by gods for muscle growth.




Insulin plus metformin is also pretty good, for health.

Metformin improves insulin sensitivity, Some users take metformin on off days to keep their natural insulin response sharp.
Dose 500 to 1000mg daily.


Not mandatory but helpful for long term health.



View attachment 5308513

Injection Technique


Insulin syringes are 1cc capacity, 29 to 31 gauge, half inch length.

These are tiny needles. Almost painless.

If you use insulin pens, 4mm to 8mm pen needles are even smaller and more convenient.

The abdomen is the standard site.

Fastest absorption

Avoid the exact center, so rotate it.


Clean the site with alcohol and let it dry.

Pinch a fold of skin.

Insert the needle at 90 degrees.

Inject slowly.

Hold for 5 to 10 seconds before withdrawing.

Do not rub the site after.

This can alter absorption speed.

Unopened insulin should be refrigerated at 2 to 8 degrees Celsius. Do not freeze.
Opened insulin can stay at room temperature for 28 days. Keep away from heat and sunlight.


View attachment 5308513

Cycling and Duration


Most bodybuilders use insulin in cycles of 4 to 8 weeks.
Some extend to 12 weeks.

Year round use is retarded and leads to insulin resistance.

Take equal or longer time off.

8 weeks on, 8 to 12 weeks off.

Use the off time to restore insulin sensitivity. Metformin and berberine help during off periods.

Use insulin primarily during bulking phases
The extra calories and insulin create maximum growth


Do not use insulin during cutting, the risk of hypoglycemia is higher in a calorie deficit.

Your body has less glucose to work with.

Do not use insulin if you have a history of hypoglycemia

Do not use if you have diabetes or prediabetes

Do not use if you cannot commit to strict diet and monitoring



View attachment 5308513

Pain Management and Ancillary

This covers drugs that can help with recovery, side effects, and overall experience while using insulin.

Not all of these are necessary. Pick what applies to your situation.

Ibuprofen and Acetaminophen
OTC pain reliefer


Useful for injection site soreness training related joint pain
general aches


ibu 400 to 600mg every 6 hours.
Aceta 500 to 1000mg every 6 hours





Aromatase Inhibitors

If you are running test or other aromatizing steroids alongside insulin

Arimidex (anastrozole)
0.5mg EOD

Aromasin (exemestane) at 12.5mg EOD


Blood work confirms need.

Do not crash your estrogen.

You need it for joint health and mood
.

Cabergoline
If you are using nandrolone or tren,
prolactin can rise.

High prolactin causes gyno, sexual dysfunction, and mood issues.

Cabergoline 0.25mg twice weekly

Nolvadex (tamoxifen)

SERM
Used for gyno reversal

20mg daily

Liver Support

If using oral steroids alongside insulin, protect your liver.
TUDCA 250 to 500mg daily
NAC at 600 to 1200mg daily.


Cardiovascular support

Insulin and AAS both strain your heart.
Fish oil 3 to 6 grams daily for triglycerides
CoQ10 at 100 to 200mg daily for heart energy
Citrus bergamot for cholesterol support
Garlic extract for blood pressure

Sleep Aids
Melatonin
3 to 10mg before bed Magnesium glycinate 400mg before bed

Digestive Enzymes
Betaine HCl
with protein meals. Pancreatic enzymes with large meals. Probiotics daily for gut health.



References




https://pubmed.ncbi.nlm.nih.gov/16705065/



https://pmc.ncbi.nlm.nih.gov/articles/PMC2804964/



https://pmc.ncbi.nlm.nih.gov/articles/PMC5241558/




https://pmc.ncbi.nlm.nih.gov/articles/PMC5723243/



https://pmc.ncbi.nlm.nih.gov/articles/PMC10973313/



https://pmc.ncbi.nlm.nih.gov/articles/PMC9153835/



https://www.sciencedirect.com/org/science/article/pii/S0250688224000033




Sadly won't read but still high effort thread
 
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too many words...
 
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Reactions: Amuzant, Punjabi Waffen and catboy09
Insulin Thread:
A Complete Guide to Bodybuilding Use


View attachment 5308513

What This Guide Covers

This is a step by step walkthrough for roiders interested in insulin use. We will cover what insulin is, why bodybuilders use it, the different types, dosing, safety measures, diet requirements, side effects, and everything you need to know before using this compound.

small continuation of
Thread 'The MOST Underrated Bodybuilding Compound - An Introduction to Insulin' https://looksmax.org/threads/the-mo...-compound-an-introduction-to-insulin.1913581/


View attachment 5308513

What Is Insulin and Why Bodybuilders Use It

View attachment 5308499

Insulin is a hormone produced by your pancreas. Its main job is to regulate blood sugar by moving glucose from your blood into your cells. Without insulin your cells starve even when your blood is full of sugar. This is what happens in Type 1 diabetes.

But here is why bodybuilders care about
it. Insulin is one of the most anabolic hormones in the human body. It drives nutrients into muscle cells


Protein
carbs
creatine
amino acids


Everything your muscles need to grow. It also suppresses muscle breakdown which means it is anti catabolic too.

The anabolic potential of insulin has been recognized since it was first used for diabetes treatment. It exerts these effects by increasing the transport of glucose and amino acids into skeletal muscle fibers, thereby increasing protein synthesis and decreasing protein degradation. Insulin binds to its receptor, causing phosphorylation of insulin receptor substrate proteins, which activates the PI3K/Akt pathway. This pathway is a key mediator contributing to muscle protein synthesis and can be activated by growth factor signaling such as insulin and IGF1.

Now here is the thing about protein synthesis.

Research shows that insulin at normal physiological levels
does not actually stimulate muscle protein synthesis directly in healthy humans in the postabsorptive state.
What it does is


suppress muscle protein breakdown

achieves muscle protein anabolism by inhibiting muscle protein breakdown


not by ramping up synthesis.

However, when amino acid levels are elevated, such as after a protein rich meal, insulin can stimulate muscle protein synthesis as long as it concomitantly increases muscle blood flow and amino acid delivery. This is why the meal timing and carb loading around insulin use is so critical. You need those amino acids present for insulin to do its anabolic work.

Bodybuilders also use insulin because it creates insane muscle pumps. Your muscles look fuller and rounder because glycogen and water are forced into the cells. This is why competitors use it before shows. It also directs where your calories go.

With insulin, more calories go to muscle and fewer go to fat.
This assumes your diet is clean and your training is intense

if you eat like garbage, insulin will store everything as fat.

Insulin also amplifies the effects of growth hormone and IGF1. Many advanced bodybuilders stack all three for maximum growth. The combination is called


the holy trinity of bodybuilding

GH raises blood sugar
Insulin lowers it.

They balance each other.

GH increases IGF1 production
Insulin drives IGF1 into cells



View attachment 5308513

Types of Insulin

Not all insulin is the same

Different types have different onset times, peaks, and durations. Bodybuilders primarily use fast acting insulins because they are predictable and controllable.



View attachment 5308463

Humalog (insulin lispro)
is the most popular choice for bodybuilders.

Onset is 15 minutes

Peak is 30 to 90 minutes
Duration is 3 to 5 hours


Fast onset
manageable duration
predictable.



Novolog (insulin aspart)
very similar to Humalog

Onset is 10 to 20 minutes

Peak is 1 to 3 hours
Duration is 3 to 5 hours


Some users report slightly faster onset.
If Humalog is not available
Novolog is a direct substitute.

Apidra (insulin glulisine)
the fastest rapid acting insulin.

Onset is 10 to 15 minutes

Peak is 1 to 2 hours
Duration is 3 to 5 hours


Good for pre workout use when you want the fastest possible nutrient delivery.

Humulin R (regular insulin)

old school

Onset is 30 minutes
Peak is 2 to 4 hours
Duration is 5 to 8 hours


Slower than the analogs above. Some old school bodybuilders still prefer it. Requires more planning because the window is longer. If you use Humulin R you need to be eating carbs for a longer period.

Lantus (insulin glargine)
long acting basal insulin.


Onset is 1 to 2 hours
No verified peak
Duration is 20 to 24 hours


Some bodybuilders use it for background anabolism throughout the day.

Much harder to control and higher risk of nocturnal hypoglycemia

I do not recommend this for beginners



NPH (intermediate acting)

has an onset of 1 to 2 hours

peak of 4 to 8 hours
and a duration of 12 to 18 hours


Not commonly used in bodybuilding. Unpredictable peak makes dosing difficult.

Avoid this.

If you are starting out, use Humalog or Novolog. They are fast, predictable, and forgiving.

Avoid NPH until you have extensive experience.

and just avoid Lantus entirely unless you have a medical reason.


View attachment 5308513


Dosing Protocols

Never start high.


View attachment 5308474

2 to 4 IU is the standard beginner dose.
some other people on other bodybuilding forums recommend
starting at 1 IU to assess sensitivity, but theyre just pussies:lul:

You can always increase

users with some experience typically run 5 to 10 IU per injection.

Advanced users go 10 to 20 IU.


Elite professionals use 20 to 40 plus IU per injection

Higher doses require
more carbs
more monitoring
more experience

Do not jump to high doses because you read chad does it. Chad has teams of doctors slaves and coaches monitoring him around the clock.

You probably do not becuase youre subhuman and no one wants to be your coach nor doctor yet alone a slave

The most common timing protocol is pre workout.

You inject 15 to 20 minutes before training.

Then you consume 10 grams of carbs per IU of insulin within 15 minutes of injection.

You train for 60 to 90 minutes.

Then you consume another 10 grams of carbs per IU immediately post workout.

Then you eat a full meal 60 to 90 minutes post workout.


So if you use 5 IU Humalog pre workout, that is 50 grams carbs pre, 50 grams carbs post, then a full meal.

Some people prefer post workout protocol

Inject immediately after training. Consume 10 grams of carbs per IU right away.
Eat a full meal 30 to 60 minutes later.


This is simpler because you are already at the gym and your post workout shake is ready.

Intra workout protocol

injecting at the start of training and sipping a carb drink throughout the workout at 10 grams carbs per IU.

Then eating a full meal immediately after.


This works well if you have a long training session and want constant nutrient delivery.

Advanced users sometimes do multiple daily injections.

Morning, pre workout, post workout, before bed.

This keeps insulin levels elevated throughout the day.

Much higher risk.


The Lantus protocol

injecting once daily in the morning at 10 to 30 IU depending on body weight and experience.

You eat consistent meals every 3 to 4 hours.

You monitor blood glucose constantly.

You have fast carbs available at all times.

Again, I do not recommend this. The risk of nocturnal hypoglycemia is too high,


INB4 slin is safe muh self administer

i dont care you little jeet i want you to reduce the harm


View attachment 5308513

Diet and Carb Requirements

View attachment 5308489

Insulin without carbs is a death sentence. You must eat enough carbs to match your insulin dose. This is the number one rule. Break this rule and you will end up in the hospital or worse.

Start with
10 grams of carbs per IU of insulin.


This is the conservative baseline.

Some users need more. Some need less.
You figure this out through blood glucose monitoring.

Never guess. Always test.

Always have fast acting carbs within arm's reach when insulin is active.

Glucose tablets are 4 grams each and have the fastest absorption.

Fruit juice is 20 to 30 grams per cup.


Honey is 17 grams per tablespoon.

Candy like Skittles or gummy bears works.

Regular soda like Coke or Sprite is 40 grams per can.

Your pre workout meal should be complex carbs, protein, and moderate fat.

Intra workout should be simple carbs only.
Dextrose, maltodextrin, or cyclic dextrin.

Post workout should be fast carbs plus protein.
Whey isolate, white rice, potatoes.

Then your follow up meal should be complex carbs, protein, and if you can handle them, vegetables.

Insulin drives amino acids into muscle cells too.

Aim for 1 to 2 grams of protein per pound of bodyweight daily.
Spread across 5 to 6 meals.


Whey isolate post workout is ideal because it digests fast and gets those amino acids into your bloodstream when insulin is peaking.

Keep fat low around insulin injections.

Fat slows carb absorption and makes timing unpredictable.

Keep pre and post workout meals low fat.

Higher fat meals are fine when insulin is not active.

This is why you see bodybuilders eating egg whites and chicken breast around workouts but steak and nuts later in the day.


View attachment 5308513

Blood Glucose Monitoring

This is non negotiable.

You must monitor your blood glucose every time you use insulin.
No exceptions.
Not once in a while.

Every
single
time.


You need a glucometer.

Any pharmacy brand works.
OneTouch, AccuChek, Contour.


View attachment 5308494

Buy test strips in bulk. You will use many. You also need lancets for finger pricks.

Test before injection to get your baseline.

Test 15 minutes after injection

Test 30 minutes after injection

Test every 30 minutes during insulin activity

Test before bed if insulin was used within 4 hours


This sounds like a lot. It is.
But it is what keeps you alive.

i dont want you dying on me


Normal fasting blood glucose is 70 to 100 mg/dL.
Post meal should be under 140 mg/dL.


On insulin, never let yourself drop below 70 mg/dL.

Hypoglycemia is the main danger.

shakiness
sweating
confusion
rapid heartbeat
hunger
irritability
blurred vision
dizziness.

Below 50 mg/dL you can lose consciousness.


Below 40 mg/dL you can have seizures or die.

I am not exaggerating, on chinas soul

Hyperglycemia is less immediately dangerous but causes long term damage.

excessive thirst
frequent urination
fatigue
blurred vision.


If your blood sugar drops, consume 15 to 20 grams of fast carbs immediately.

Wait 15 minutes. Retest.


If still below 70, consume another 15 to 20 grams. Repeat until blood glucose is above 80.

Then eat a balanced meal once stable.


If you pass out, whoever is with you needs to call emergency services.

If they have glucagon, they should administer it.


View attachment 5308513


Safety Rules

Rule 1, Never use insulin alone. Always have someone nearby (wouldnt reccomend girlfriend if you have one) who knows you are using it and what to do if you pass out. Tell them where your glucose tablets are. Show them how to use your glucometer.

Rule 2. Fast carbs within reach everywhere. Glucose tablets in your pocket. Juice in your gym bag. Candy on your nightstand. Everywhere insulin is active, fast carbs must be within 30 seconds reach.

Rule 3. Start low. 2 to 4 IU maximum for your first time. Do not increase until you have used that dose multiple times without issues. Increase by 1 to 2 IU at a time. Not 5 or 10.

Rule 4. No alcohol. Alcohol lowers blood sugar.
Combining with insulin is extremely dangerous. Do not drink on insulin days.

Rule 5. Test before bed.
If insulin was active within 4 hours of bedtime, test your blood glucose before sleeping. If it is below 100, eat a slow carb snack like oatmeal or toast with peanut butter. This prevents nocturnal hypoglycemia. Dying in your sleep is very bad.


Rule 6. Know your insulin duration. Humalog and Novolog last 3 to 5 hours. Do not inject again until at least 5 hours have passed unless you are an advanced user with constant monitoring.

Rule 7. Do not skip meals, you anorexic bitch.
If you inject insulin,
you must eat. No exceptions. Even if you are not hungry. Even if you feel sick. The insulin will drop your blood sugar regardless.



View attachment 5308513

Side Effects and Risks

Hypoglycemia is the number one risk.

seizures
brain damage
coma
death


Most insulin related deaths in bodybuilding are from hypoglycemia, not long term complications. This happens when someone miscalculates carbs, skips a meal, or trains harder than expected and burns through glucose too fast.


Insulin resistance is the long term danger.

Chronic high dose insulin use can make your body resistant to its own insulin.

This leads to Type 2 diabetes.

Risk increases with


dose
duration
bf%


Constant physical exercise prevents insulin resistance in the short term. But the long term effects of repeated insulin abuse are not fully understood.

Stay lean mothafuckaaaa
Cycle insulin
Do not use year round, youre not pro


Water retention happens to everyone.
Insulin causes subcutaneous water retention, You look puffy and bloated.

This is temporary

Some bodybuilders use diuretics before shows to shed water

Gyno can occur because insulin can increase estrogen indirectly by raising IGF1 and promoting aromatization.
if you are prone to gyno, monitor for lump formation and use an aromatase inhibitor if needed.

Insulin promotes fat storage in arteries and increases inflammation

Lipohypertrophy
repeated injections in the same spot cause fat lumps under the skin.



These lumps can alter insulin absorption and make dosing unpredictable.

Rotate injection sites

Abdomen
thighs
deltoids

dem as cheeks

Do not inject into lumps.


View attachment 5308513

Stacking and Synergy

Insulin plus GH is the classic stack.

as said before



Time insulin around meals and workouts.

Insulin plus IGF1 LR3 is even more potent.

IGF1 LR3 is a synthetic version of insulin like growth factor 1.
It directly stimulates muscle growth.
Combined with insulin,
the effect is amplified.

IGF1 can cause gut growth and organ enlargement. You do not want a distended abdomen.

Insulin plus anabolic steroids is the standard.
Test, tren, bold,
and other AAS
increase protein synthesis.

Insulin increases nutrient delivery.


Together they create the perfect nectar given by gods for muscle growth.




Insulin plus metformin is also pretty good, for health.

Metformin improves insulin sensitivity, Some users take metformin on off days to keep their natural insulin response sharp.
Dose 500 to 1000mg daily.


Not mandatory but helpful for long term health.



View attachment 5308513

Injection Technique


Insulin syringes are 1cc capacity, 29 to 31 gauge, half inch length.

These are tiny needles. Almost painless.

If you use insulin pens, 4mm to 8mm pen needles are even smaller and more convenient.

The abdomen is the standard site.

Fastest absorption

Avoid the exact center, so rotate it.


Clean the site with alcohol and let it dry.

Pinch a fold of skin.

Insert the needle at 90 degrees.

Inject slowly.

Hold for 5 to 10 seconds before withdrawing.

Do not rub the site after.

This can alter absorption speed.

Unopened insulin should be refrigerated at 2 to 8 degrees Celsius. Do not freeze.
Opened insulin can stay at room temperature for 28 days. Keep away from heat and sunlight.


View attachment 5308513

Cycling and Duration


Most bodybuilders use insulin in cycles of 4 to 8 weeks.
Some extend to 12 weeks.

Year round use is retarded and leads to insulin resistance.

Take equal or longer time off.

8 weeks on, 8 to 12 weeks off.

Use the off time to restore insulin sensitivity. Metformin and berberine help during off periods.

Use insulin primarily during bulking phases
The extra calories and insulin create maximum growth


Do not use insulin during cutting, the risk of hypoglycemia is higher in a calorie deficit.

Your body has less glucose to work with.

Do not use insulin if you have a history of hypoglycemia

Do not use if you have diabetes or prediabetes

Do not use if you cannot commit to strict diet and monitoring



View attachment 5308513

Pain Management and Ancillary

This covers drugs that can help with recovery, side effects, and overall experience while using insulin.

Not all of these are necessary. Pick what applies to your situation.

Ibuprofen and Acetaminophen
OTC pain reliefer


Useful for injection site soreness training related joint pain
general aches


ibu 400 to 600mg every 6 hours.
Aceta 500 to 1000mg every 6 hours





Aromatase Inhibitors

If you are running test or other aromatizing steroids alongside insulin

Arimidex (anastrozole)
0.5mg EOD

Aromasin (exemestane) at 12.5mg EOD


Blood work confirms need.

Do not crash your estrogen.

You need it for joint health and mood
.

Cabergoline
If you are using nandrolone or tren,
prolactin can rise.

High prolactin causes gyno, sexual dysfunction, and mood issues.

Cabergoline 0.25mg twice weekly

Nolvadex (tamoxifen)

SERM
Used for gyno reversal

20mg daily

Liver Support

If using oral steroids alongside insulin, protect your liver.
TUDCA 250 to 500mg daily
NAC at 600 to 1200mg daily.


Cardiovascular support

Insulin and AAS both strain your heart.
Fish oil 3 to 6 grams daily for triglycerides
CoQ10 at 100 to 200mg daily for heart energy
Citrus bergamot for cholesterol support
Garlic extract for blood pressure

Sleep Aids
Melatonin
3 to 10mg before bed Magnesium glycinate 400mg before bed

Digestive Enzymes
Betaine HCl
with protein meals. Pancreatic enzymes with large meals. Probiotics daily for gut health.



References




https://pubmed.ncbi.nlm.nih.gov/16705065/



https://pmc.ncbi.nlm.nih.gov/articles/PMC2804964/



https://pmc.ncbi.nlm.nih.gov/articles/PMC5241558/




https://pmc.ncbi.nlm.nih.gov/articles/PMC5723243/



https://pmc.ncbi.nlm.nih.gov/articles/PMC10973313/



https://pmc.ncbi.nlm.nih.gov/articles/PMC9153835/



https://www.sciencedirect.com/org/science/article/pii/S0250688224000033




Dnr BOTB material good thread
 
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Unicorn font colors fuck me
 
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will read
 
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@tuberculosisinmybal @Pony @Gengar’s Ghost

plz move to looksmax
 
can the mods do their fucking job
 
@0ogrpostcel @negative
 
good user
gonna read this

you remind me of @A
 
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good user
gonna read this

you remind me of @A
i sadly posted it in offtopic and no one wants to put it in looksmax
 
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i sadly posted it in offtopic and no one wants to put it in looksmax
just wait some time you will be actually getting reps u wouldn't get in looksmax
 
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dnr but im mirin the effort
 
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@Sadist Did he pop off with this one
 
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DNR bookmarked will read later
 
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