
Mariuszek
Iron
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- May 25, 2025
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for educational purposes only, I am not responsible for any harm
1.What is Intermittent Hypoxic Training (IHT)?
Intermittent Hypoxic Training (IHT) is a biohacking technique where you voluntarily expose your body to short bursts of low oxygen. To trigger adaptive responses like increased bone mineral density, improved blood flow to facial tissues and enhanced GH/TESTOSTERONE production all which can enchance facial structure and also skin health.
2.How it works?
When you expose your body to low oxygen controlled (hypoxia) for short time, cupple powerful phsiological adaptations are triggered:
1.HIF-1α Activation (Hypoxia-Inducible Factor 1-alpha)
-Hypoxia activates HIF-1α a gene transcription factor
-HIF-1α boosts production of:
-VEGF (Vascular Endothelial Growth Factor) - it increases blood vessel growth
-EPO (Erythropoietin) – it stimulates red blood cell production.
-IGF-1 -anabolic hormone for tissue growth
-What does it do:
-improved blood circulation to skin and bones.
-increased nutrient delivery to your facial bones and skin

Source of the image: https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2022.1067411/full
This Image shows the cellular mechanisms triggered by hypoxia (Low O2 levels) and hyperoxia (High O2 levels) This helps understand how IHT works
What does it show?:
-On the Hyperoxia side (left)(High O2):
-Excess oxygen leads to ROS(Reactive Oxygen Species) production
-ROS activates the Nrf2 pathway which promotes:
Antioxidant gene expression.
Anti inflammatory responses.
Growth factor production.
Metabolic support and cell survival.
-On the Hypoxia side (right)(Low O2):
-Low oxygen also generates ROS, though in lower amounts.
-Hypoxia triggers HIF-α activation:
-HIF-α binds with HIF-β, stimulating genes related to:
VEGF- angiogenesis (new blood vessels)
iNOS -> NO-> vasodilation (expansion of blood vessels)
CBF regultion (cerebral blood flow)
Metabolic adaptation
cell survival
IGF-1 Production - anabolic effects, bone growth collagen synthesis
2. Bone Remodeling and Mineralization
-hypoxia stresses bones at the cellular level
-osteoblast activity increases as an adaptive response
What are the results: increased bone mineral density (BMD), making facial bones denser and more prominent.Stronger jawline,cheekbones,and overall facial structure
3. Hormonal boost:
-Short hypoxic strss triggers natural spike in GH (Growth Hormone)
-May also increase testosterone production indirectly , improved sleep quality and stress adaptation
-These hormones support collagen production and facial bone mass.
4.Improved Skin Blood Circulation
-Causes vasodilation when oxygen returns to normal levels more blood rushes to the skin which results in improved facial skin tone and healthier appearance.

Source of image: https://www.optimusmedica.com/intermittent-hypoxic-training-iht/
WARNING!!:
Overdoing it may cause dizzines z fainting and excessive oxidative stress
for educational purposes only